Cholangiocarcinoma — evolving concepts and therapeutic strategies
Ilyas, Sumera I., Khan, Shahid A., Hallemeier, Christopher L., Kelley, Robin K., Gores, Gregory J.·2018·Nature Reviews Clinical Oncology
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- Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific VulnerabilitiesAlexander Scheiter, Frederik Hierl, Ingrid Winkel, Felix Keil, Margit Klier-Richter, Cédric Coulouarn, Florian Lüke, Arne Kandulski, Matthias Evert, Wolfgang Dietmaier et al. · 2022 · Journal of Personalized Medicine
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- Systemic treatment of patients with locally advanced or metastatic cholangiocarcinoma – an Austrian expert consensus statementHossein Taghizadeh, Angela M. Djanani, Wolfgang Eisterer, Armin Gerger, Birgit Gruenberger, Thomas Gruenberger, Holger F. Rumpold, Lukas Weiß, Thomas L. Winder, Ewald Wöll et al. · 2023 · Frontiers in Oncology
- LncRNA-HANR exacerbates malignant behaviors of cholangiocarcinoma cells through activating Notch pathwayGuoqing Zhou, Hongwei He, Xu'an Wang, Qiyun Gu · 2023 · Heliyon
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- Huaier inhibits cholangiocarcinoma cells through the twist1/FBP1/Wnt/β-catenin axisLiyuan Cong, Jian Shi, Jing Zhao, Kun Li, Dongdong Dai, Bingyuan Zhang, Wei Zhao · 2024 · Molecular Biology Reports
- Identification of autoantibodies as potential non-invasive biomarkers for intrahepatic cholangiocarcinomaWachira Kajornsrichon, Jittiporn Chaisaingmongkol, Yotsawat Pomyen, Phanthakarn Tit-oon, Xin Wei Wang, Mathuros Ruchirawat, Mayuree Fuangthong · 2024 · Scientific Reports
- Associations between metabolic syndrome and cholangiocarcinoma risk: A large-scale population-based cohort studyTzu-I Chen, Minghuang Chen, Szu‐Ching Yin, Chih-Jo Lin, Tram Kim Lam, Chia-Wei Huang, Yi‐Ting Chen, Xia-Rong Liu, Yun-Zheng Gao, Wan‐Lun Hsu et al. · 2025 · Hepatology
- Proteomic profiling reveals common and region-specific protein signatures underlying tumor heterogeneity in cholangiocarcinomaSirinya Sitthirak, Sittiruk Roytrakul, Arporn Wangwiwatsin, Nisana Namwat, Poramate Klanrit, Hasaya Dokduang, Prakasit Sa-Ngiamwibool, Attapol Titapan, Apiwat Jareanrat, Vasin Thanasukarn et al. · 2025 · Scientific Reports
- Evaluation of Primary Liver Cancers Using Hepatocyte‐Specific Contrast‐Enhanced MRI : Pitfalls and Potential TipsJae Hyun Kim, Jeong Hee Yoon, Ijin Joo, Jeong Min Lee · 2020 · Journal of Magnetic Resonance Imaging
- Combining PD-1 Inhibitor with VEGF/VEGFR2 Inhibitor in Chemotherapy: Report of a Patient with End-Stage Cholangiocarcinoma and Review of LiteratureZhenjiang Ma, Heping Li, Liangshuai Liu · 2021 · Recent Patents on Anti-Cancer Drug Discovery
- A redox probe screens MTHFD1 as a determinant of gemcitabine chemoresistance in cholangiocarcinomaRuogu Pan, Zhiqing Yuan, Yingbin Liu, Xuxu Sun, Guiyang Wang, Xiaopen Wang, Junwen Qu, Jian Wang, Jie Yang, Yuzheng Zhao et al. · 2021 · Cell Death Discovery
- Minimally Invasive Surgery for Intrahepatic Cholangiocarcinoma: Patient Selection and Special ConsiderationsMackenzie Owen, Eliza Wright Beal · 2021 · Hepatic Medicine Evidence and Research
- CEACAM6 promotes cholangiocarcinoma migration and invasion by inducing epithelial‑mesenchymal transition through inhibition of the SRC/PI3K/AKT signaling pathwayChen Liu, Min Wang, Haitao Lv, Bing Liu, Xueqiang Ya, Weihong Zhao, Wenbin Wang · 2021 · Oncology Letters
- Crowberry inhibits cell proliferation and migration through a molecular mechanism that includes inhibition of DEK and Akt signaling in cholangiocarcinomaXue Wang, Xuebing Zhou, Ludan Zhang, Xin Zhang, Chunyu Yang, Yingshi Piao, Jinhua Zhao, Lili Jin, Guihua Jin, Ren‐Bo An et al. · 2022 · Chinese Medicine
- Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cellsYongfei He, Yanghong Li, Tianyi Liang, Shutian Mo, Yuan Liao, Zijun Chen, Shuqi Zhao, Qingfu Ran, Chuangye Han, Pham Thi Thai Hoa · 2022 · Journal of Gastrointestinal Oncology
- Potential of Alpha-Mangostin-Loaded PLGA Nanoparticles for Cholangiocarcinoma TreatmentAsma Tahir, Tullayakorn Plengsuriyakarn, Chuda Chittasupho, Kesara Na‐Bangchang · 2022 · Polymers
- Second-Line Chemotherapy in Elderly Patients with Advanced Biliary Tract Cancer: A Multicenter Real-World StudyAlessandro Rizzo, Massimiliano Salati, Giorgio Frega, Valeria Merz, Francesco Caputo, Alessandro Di Federico, Andrea Palloni, Riccardo Carloni, Angela Dalia Ricci, Gennaro Gadaleta‐Caldarola et al. · 2022 · Medicina
- A meta-analysis of based radiomics for predicting lymph node metastasis in patients with biliary tract cancersYuhu Ma, Yanyan Lin, Jiyuan Lu, Yulong He, Qianling Shi, Haoran Liu, Jianlong Li, Baoping Zhang, Jinduo Zhang, Yong Zhang et al. · 2023 · Frontiers in Surgery
- SSH1 promotes progression of intrahepatic cholangiocarcinoma via p38 MAPK-CXCL8 axisFanghua Chen, Ling Aye, Lei Yu, Longzi Liu, Yuming Liu, Youpei Lin, Dongmei Gao, Qiang Gao, Shu Zhang · 2023 · Carcinogenesis
- Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomasXiaohong Pu, Liang Qi, Jia Wu Yan, Zihe Ai, Ping Wu, Fei Yang, Yao Shi Fu, Xing Li, Min Zhang, Beicheng Sun et al. · 2023 · Cell & Bioscience
- Long‐term oncological results of percutaneous radiofrequency ablation for intrahepatic cholangiocarcinomaClémentine Alitti, Agnès Rode, Hervé Trillaud, Philippe Merle, Jean‐Frédéric Blanc, Lorraine Blaise, Alix Demory, G. Nkontchou, Véronique Grando, Marianne Ziol et al. · 2024 · Liver International
- Intrahepatic cholangiocarcinoma as a rare secondary malignancy after allogeneic hematopoietic stem cell transplantation for childhood acute lymphoblastic leukemia: A case reportMeghan L. Good, Parisa Malekzadeh, Isaac R. Kriley, Nirali N. Shah, David Erwin Kleiner, Katherine R. Calvo, Jonathan Matthew Hernandez, Jeremy L. Davis · 2020 · Pediatric Transplantation
- Analysis of Patients With Incidental Perihilar Cholangiocarcinoma: An Old and a Persistent Burden for Liver TransplantationMaciej Krasnodębski, Michał Grąt, Michał Wierzchowski, Michalina Szczęśniak, Marcin Morawski, Krzysztof Zając, Waldemar Patkowski, Krzysztof Zieniewicz · 2020 · Transplantation Proceedings
- Pathological aspects of mucinous cholangiocarcinoma: A single‐center experience and systematic reviewThiyaphat Laohawetwanit, Naruemon Klaikaew · 2020 · Pathology International
- SOX2 knockdown slows cholangiocarcinoma progression through inhibition of transcriptional activation of lncRNA PVT1A.M.Y. Yu, Luwen Zhao, Qingmin Kang, Jian Li, Kai Chen, Hua Fu · 2020 · Biochemical Journal
- Mesencephalic Astrocyte-Derived Neurotrophic Factor, a Prognostic Factor of Cholangiocarcinoma, Affects Sorafenib Sensitivity of Cholangiocarcinoma Cells by Deteriorating ER StressJingyi He, Guangbing Li, Xihan Liu, Liye Ma, Jiayao Zhang, Shunzhen Zheng, Jianping Wang, Jun Liu · 2020 · OncoTargets and Therapy
- Cholangiocarcinoma Therapeutics: An UpdateMai Ly Thi Nguyen, Nguyễn Lĩnh Toàn, Maria Bożko, Khắc Cường Bùi, Przemyslaw M. Bozko · 2021 · Current Cancer Drug Targets
- Current challenges to underpinning the genetic basis for cholangiocarcinomaAntonio Cigliano, Xin Chen, Diego Francesco Calvisi · 2021 · Expert Review of Gastroenterology & Hepatology
- The role of bile acid subtypes in the diagnosis of cholangiocarcinomaWei Wang, Shi‐Lin Tian, Die Jin, Bin Liu, Wujie Wang, Haiyang Chang, Chao Chen, Zhe Yu, Yong‐Zheng Wang, Yuliang Li · 2021 · Asia-Pacific Journal of Clinical Oncology
- The association of carbohydrate antigen 19‐9 response with radiologic response and survival in intrahepatic cholangiocarcinoma: A prospective cohort studyQuan‐Yu Cai, Ping Yang, Xiao‐Liang Yang, Xiang‐Hua Zhang, Lie‐Ping Guo, Xinyuan Lu, Lei Huo, Hongbin Ma, Xiangdong Wang, Huabang Zhou et al. · 2023 · Cancer
- Beyond the Bile: Exploring the Microbiome and Metabolites in CholangiocarcinomaJungnam Lee, Hanul Kim, Jin‐Seok Park · 2024 · Life
- Influence of Perineural (Pn), Lymphangio (L) and Vascular (V) Invasion on Survival after Resection of Perihilar CholangiocarcinomaRabea Margies, Lisa-Katharina Gröger, Beate Katharina Straub, F. Bartsch, Hauke Lang · 2024 · Cancers
- Prognostic role of claudin-18.2 in intrahepatic cholangiocarcinomaYu‐Hsuan Kuo, Khaa Hoo Ong, Ding‐Ping Sun, Yufeng Tian, Chia‐Ling Chou, Ti‐Chun Chan, Chung‐Hsi Hsing, Wan‐Shan Li, Chien‐Feng Li, Yow‐Ling Shiue · 2025 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
- Circ_0084927 promotes progression of intrahepatic cholangiocarcinoma by sponging miR-4725-5p to activate the PDPK1/AKT/mTOR signaling pathwayChenxi Xie, Gengping Zhou, Taiyang Chen, Qingshan Li, Hao Yuan, Yang Xu, Kai Zhang, Chunmei Wang, Xiaopei Hao, Haibo Yu · 2025 · Cellular Signalling
- IFN-γ enhances Poly(I:C)-induced necroptosis and immunogenic cell death via TLR3 upregulation in cholangiocarcinoma cellsApiwit Sae-Fung, Thanpisit Lomphithak, Nattaya Duangthim, Siriporn Jitkaew · 2025 · European Journal of Pharmaceutical Sciences
- Multiomics combined with machine learning defines unique molecular subtypes of cholangiocarcinoma and identifies TNK1 as a therapeutic targetDong‐Gi Mun, Erik Jessen, Jennifer L. Tomlinson, Danielle Marie Carlson, Rohit Budhraja, Roberto Alva‐Ruiz, Amro M. Abdelrahman, Ryan D. Watkins, Lindsey A. Gregory, Chantal E. McCabe et al. · 2025 · Hepatology
- Interventional oncology: A primer for clinicians on the role of ablation and embolization for solid tumorsMohamed E. Abdelsalam, Kamran Ahrar, Rahul A. Sheth, Ketan Y. Shah, Steven M. Yevich, Varshana Gurusamy, Bruno Calazans Odisio, Alda Lui Tam, Armeen Mahvash, Peiman Habibollahi · 2025 · CA A Cancer Journal for Clinicians
- Liquid biopsy in biliary tract cancers: early diagnosis, precision therapy, and prognostic evaluationGuanhua Wu, Xinjian Xu, Honghua Zhang, Peng Li, Chao Liu · 2025 · Frontiers in Oncology
- L-lactate-driven PSMD14 lactylation and stabilization promote lactate production and ferroptosis resistance via ENO1 in intrahepatic cholangiocarcinomaDong Cai, Guo‐Chao Zhong, Zhibo Zhao, Menglin Chen, Qing Tao, Xin Dai, Degong Jia, LVE CHENG, Zhenru Wu, Shengwei Li et al. · 2026 · Cancer Letters
- Spatiotemporal regulation of cholangiocarcinoma growth and dissemination by peritumoral myofibroblasts in a Vcam1-dependent mannerCheng Lin Tian, Liyuan Li, Qingfei Pan, Beisi Xu, Yizhen Li, Fan Li, Anthony Ray Brown, Michelle Morrison, Kaushik Dey, Jun J.J. Yang et al. · 2023 · Oncogene
- Survival trends over 20 years in patients with advanced cholangiocarcinoma: Results from a national retrospective analysis of 922 cases in ItalyAndrea Casadei Gardini, Francesco Leone, Giovanni Brandi, Mario Scartozzi, Nicola Silvestris, Daniele Santini, Luca Faloppi, Massimo Aglietta, Maria Antonietta Satolli, Alessandro Rizzo et al. · 2023 · Frontiers in Oncology
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- Molecular Biomarkers in Cholangiocarcinoma: Focus on BileAndrey D. Dolbnya, Igor A. Popov, Пеков Станислав Игоревич · 2024 · Current Topics in Medicinal Chemistry
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