Tau-based therapies in neurodegeneration: opportunities and challenges
Cites (229)
Items 201–229 of 229
- Stimulation of EphB2 attenuates tau phosphorylation through PI3K/Akt-mediated inactivation of glycogen synthase kinase-3βJun Jiang, Zhi-Hao Wang, Min Qu, Di Gao, Xiu-Ping Liu, Ling‐Qiang Zhu, Jian‐Zhi Wang · 2015 · Scientific Reports
- Ribosylation triggering A lzheimer's disease‐like T au hyperphosphorylation via activation of C a MKIIWei Yan, Chanshuai Han, Yujing Wang, Beibei Wu, Tao Su, Ying Liu, Rongqiao He · 2015 · Aging Cell
- Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathologyLixin Song, Sherry X. Lu, Xuesong Ouyang, Jerry P. Melchor, Julie Lee, Giuseppe Terracina, Xiaohai Wang, Lynn A. Hyde, J. Fred Hess, Eric M. Parker et al. · 2015 · Molecular Neurodegeneration
- Intraperitoneal Administration of a Novel TAT-BDNF Peptide Ameliorates Cognitive Impairments via Modulating Multiple Pathways in Two Alzheimer’s Rodent ModelsYuanyuan Wu, Xiaobin Luo, Xinhua Liu, Deyi Liu, Xiong Wang, Ziyuan Guo, Ling‐Qiang Zhu, Qing Tian, Xifei Yang, Jian‐Zhi Wang · 2015 · Scientific Reports
- Ginsenoside Rd attenuates beta-amyloid-induced tau phosphorylation by altering the functional balance of glycogen synthase kinase 3beta and protein phosphatase 2ALing Li, Zhirong Liu, Juanfang Liu, Xuhui Tai, Xinghua Hu, Xuedong Liu, Zhongliang Wu, Guangyun Zhang, Ming Shi, Gang Zhao · 2013 · Neurobiology of Disease
- Microtubules (tau) as an Emerging Therapeutic Target: NAP (Davunetide)Illana Gozes · 2011 · Current Pharmaceutical Design
- Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant TauD. Xia, J. M. Gutmann, J. Götz · 2016 · Scientific Reports
- Curcumin improves tau-induced neuronal dysfunction of nematodes.T. Miyasaka, Ce Xie, S. Yoshimura, Yuki Shinzaki, Sawako Yoshina, E. Kage-Nakadai, S. Mitani, Y. Ihara · 2016 · Neurobiology of Aging
- Tau Rather than TDP-43 Proteins are Potential Cerebrospinal Fluid Biomarkers for Frontotemporal Lobar Degeneration Subtypes: A Pilot StudyH. Bea Kuiperij, Alexandra A. M. Versleijen, Marijke Beenes, Nicolaas A. Verwey, Luisa Benussi, Anna Paterlini, Giuliano Gb. Binetti, Charlotte Elisabeth Teunissen, Joost Raaphorst, Helenius Jurgen Schelhaas et al. · 2016 · Journal of Alzheimer s Disease
- Diaminothiazoles Modify Tau Phosphorylation and Improve the Tauopathy in Mouse Models*Xuemei Zhang, Israel Hernández, Damien Rei, Waltraud Mair, Joydev K. Laha, Madison E. Cornwell, Gregory D. Cuny, Li‐Huei Tsai, Judith A. J. Steen, Kenneth S. Kosik · 2013 · Journal of Biological Chemistry
- Challenges, solutions, and recommendations for Alzheimer's disease combination therapyJames A. Hendrix, Randall John Bateman, H. Robert Brashear, Cynthia D. Duggan, María C. Carrillo, Lisa J. Bain, Ronald Bradley Demattos, Russell G. Katz, Susanne Ostrowitzki, Eric Siemers et al. · 2016 · Alzheimer s & Dementia
- Pittsburgh Compound‐B (PiB) binds amyloid β‐protein protofibrilsGhiam Yamin, David B. Teplow · 2016 · Journal of Neurochemistry
- Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic miceJin Chu, J. G. Li, Phillip F. Giannopoulos, Benjamin E. Blass, Wayne E. Childers, Magid A. Abou-Gharbia, Domenico Praticò · 2015 · Molecular Psychiatry
- No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin MiceAnnika van Hummel, Mian Bi, Stefania Ippati, Julia van der Hoven, Alexander M. Volkerling, Wei S. Lee, Daniel C. S. Tan, André Bongers, Arne Ittner, Yazi Diana Ke et al. · 2016 · PLoS ONE
- Truncated tau deregulates synaptic markers in rat model for human tauopathySantosh Jadhav, Stanislav Katina, Andrej Kováč, Zuzana Kazmerova, Michal Novák, Norbert Žilka · 2015 · Frontiers in Cellular Neuroscience
- Stem-cell discovery platforms yield first clinical candidatesAsher Mullard · 2015 · Nature Reviews Drug Discovery
- Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodentMiranda E. Orr, Valentina Rose Garbarino, Angelica Salinas, Rochelle Buffenstein · 2014 · Neurobiology of Aging
- Antibodies to β-Amyloid Decrease the Blood-to-Brain Transfer of β-Amyloid Peptide 1Weihong Pan, Beka Solomon, Lawrence M. Maness, Abba J. Kastin · 2002 · Experimental Biology and Medicine
- Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathiesSahabudeen Sheik Mohideen, Yasutoyo Yamasaki, Yasuhiro Omata, Leo Tsuda, Yuji Yoshiike · 2015 · Scientific Reports
- A prospective pilot study on serum cleaved tau protein as a neurological marker in severe traumatic brain injurySharad Pandey, Kulwant Singh, Vivek Sharma · 2017 · British Journal of Neurosurgery
- Amyloid-β Peptide-specific DARPins as a Novel Class of Potential Therapeutics for Alzheimer DiseaseMichael Hanenberg, Jordan McAfoose, Luka Kulic, Tobias Welt, Fabian Wirth, Petra Parizek, Lisa Strobel, Susann Cattepoel, Claudia B. Späni, Rebecca Derungs et al. · 2014 · Journal of Biological Chemistry
- Identification and characterization of natural antibodies against tau protein in an intravenous immunoglobulin productLenka Hromádková, Michala Kolarova, Barbora Jankovičová, Aleš Bartoš, Jan Říčný, Zuzana Bı́lková, Daniela Řı́pová · 2015 · Journal of Neuroimmunology
- Intravenous Immunoglobulin Reduces Tau Pathology and Preserves Neuroplastic Gene Expression in the 3xTg Mouse Model of Alzheimer’s DiseaseScott Counts, Sylvia E. Perez, Bin He, Elliott Jay Mufson · 2014 · Current Alzheimer Research
- Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitorsJason D. Katz, Andrew M. Haidle, Kaleen K. Childers, Anna A. Zabierek, James P. Jewell, Yongquan Hou, Michael D. Altman, Alexander A. Szewczak, Dapeng Chen, Andreas Harsch et al. · 2016 · Bioorganic & Medicinal Chemistry Letters
- Pharma pumps up anti-tau Alzheimer pipeline despite first Phase III failureAsher Mullard · 2016 · Nature Reviews Drug Discovery
- Activation of Autophagy by Rapamycin Does Not Protect Oligodendrocytes Against Protein Aggregate Formation and Cell Death Induced by Proteasomal InhibitionMonika Noack, Christiane Richter‐Landsberg · 2014 · Journal of Molecular Neuroscience
- Personalised and Precision Medicine in Cancer Clinical Trials: Panacea for Progress or Pandora's Box?Mark Lawler, Richard J. Sullivan · 2015 · Public Health Genomics
- Effects of Tau Domain-Specific Antibodies and Intravenous Immunoglobulin on Tau Aggregation and Aggregate DegradationJosé O. Esteves-Villanueva, Hanna Trzeciakiewicz, David A. Loeffler, Sanela Martić · 2014 · Biochemistry
- Brain Aggregates: An EffectiveIn VitroCell Culture System Modeling Neurodegenerative DiseasesMisol Ahn, Franck K. Kalume, Rose Pitstick, Abby Oehler, George A. Carlson, Stephen J. DeArmond · 2016 · Journal of Neuropathology & Experimental Neurology