The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.
Integrase inhibitors to treat HIV/Aids
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Citations
Cites
Gottlieb, M. S., Schroff, R., Schanker, H. M., Weisman, J. D., Fan, P. T., Wolf, R. A., & Saxon, A. (1981) · New England Journal of Medicine · doi:10.1056/nejm198112103052401 · Cited by 2,728
HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots
Schröder, A. R. W., Shinn, P., Chen, H., Berry, C., Ecker, J. R., & Bushman, F. (2002) · Cell · doi:10.1016/s0092-8674(02)00864-4 · Cited by 1,832
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
Song, J.-J., Smith, S. K., Hannon, G. J., & Joshua-Tor, L. (2004) · Science · doi:10.1126/science.1102514 · Cited by 1,470
Masur, H., Michelis, M. A., Greene, J. B., Onorato, I., Vande Stouwe, R. A., Holzman, R. S., Wormser, G., Brettman, L., Lange, M., Murray, H. W., et al. (1981) · New England Journal of Medicine · doi:10.1056/nejm198112103052402 · Cited by 1,434
Transcription Start Regions in the Human Genome Are Favored Targets for MLV Integration
Wu, X., Li, Y., Crise, B., & Burgess, S. M. (2003) · Science · doi:10.1126/science.1083413 · Cited by 1,305
Siegal, F. P., Lopez, C., Hammer, G. S., Brown, A. E., Kornfeld, S. J., Gold, J., Hassett, J., Hirschman, S. Z., Cunningham-Rundles, C., Adelsberg, B. R., et al. (1981) · New England Journal of Medicine · doi:10.1056/nejm198112103052403 · Cited by 1,246
Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells
Hazuda, D. J., Felock, P., Witmer, M., Wolfe, A., Stillmock, K., Grobler, J. A., Espeseth, A., Gabryelski, L., Schleif, W., Blau, C., et al. (2000) · Science · doi:10.1126/science.287.5453.646 · Cited by 1,131
Beese, L. S., & Steitz, T. A. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07917.x · Cited by 1,048
HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells
Cherepanov, P., Maertens, G., Proost, P., Devreese, B., Van Beeumen, J., Engelborghs, Y., De Clercq, E., & Debyser, Z. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209278200 · Cited by 704
Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.
Bukrinsky, M. I., Sharova, N., Dempsey, M. P., Stanwick, T. L., Bukrinskaya, A. G., Haggerty, S., & Stevenson, M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.14.6580 · Cited by 607
Research works printed but not linked: 10
- Cohen, J. Therapies. Confronting the limits of success. Science 296, 2320–2324 (2002). · doi:10.1126/science.296.5577.2320
- Werber, Y. HIV drug market. Nature Rev. Drug Discov. 2, 513–514 (2003). · doi:10.1038/nrd1135
- Brown, P. O. in Retroviruses (eds. Coffin, J. M., Hughes, S. H. & Varmus, H. E.) 161–203 (Cold Spring Harbor Press, Cold Spring Harbor, 1998).
- Kalpana, G. V. & Goff, S. P. Protein–protein interactions of HIV-1 IN: INI-1 (IN Interactor-1), a novel human gene with sequence similarity to yeast transcription factor SNF5. J. Cell. Biochem. 18B, 27 (1994).
- Dayam, R. & Neamati, N. Small-molecule HIV-1 integrase inhibitors: the 2001–2002 update. Curr Pharm Des 9, 1789–1802 (2003). · doi:10.2174/1381612033454469
- Witvrouw, M. et al. Novel inhibitors of HIV-1 integration. Curr. Drug. Metab. 5, 291–304 (2004). · doi:10.2174/1389200043335487
- Young, S. D. Inhibition of HIV-1 integrase by small molecules: the potential for a new class of AIDS chemotherapeutics. Curr. Opin. Drug Discov. Devel. 4, 402–410 (2001).
- Neamati, N. et al. Thiazolothiazepine inhibitors of HIV-1 integrase. J. Med. Chem. 42, 3334–3341 (1999). · doi:10.1021/jm990047z
- Neamati, N. et al. Depside and depsidones as inhibitors of HIV-1 integrase: Discovery of novel inhibitors through 3D database searching. J. Med. Chem. 40, 942–951 (1997). · DOI · Paper page
- Johnson, A. A. et al. Interaction between HIV-1 integrase Q148 and a viral DNA cytosine is required for strand transfer. (in the press).
Cited by
How were new medicines discovered?
Swinney, D. C., & Anthony, J. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3480 · Cited by 1,812
Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.
De Clercq, E. (2009) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2008.10.010 · Cited by 627
Novel HIV-1 Integrase Inhibitors Derived from Quinolone Antibiotics
Sato, M., Motomura, T., Aramaki, H., Matsuda, T., Yamashita, M., Ito, Y., Kawakami, H., Matsuzaki, Y., Watanabe, W., Yamataka, K., et al. (2006) · Journal of Medicinal Chemistry · doi:10.1021/jm0600139 · Cited by 328
HIV-1 Antiretroviral Resistance: Scientific Principles and Clinical Applications
Tang, M. W., & Shafer, R. W. (2012) · Drugs · doi:10.2165/11633630-000000000-00000 · Cited by 326
Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis
Sridharan, V., & Menéndez, J. C. (2010) · Chemical Reviews · doi:10.1021/cr100004p · Cited by 295
Metadata
- Authors
- Pommier, Y., Johnson, A. A., & Marchand, C.
- Venue
- Nature Reviews Drug Discovery
- Published
- 2005-02-24
- Volume
- 4
- Issue
- 3
- Pages
- 236-248
- ISSN
- 1474-1776 (ISSN-L)
- 1474-1784
- OpenAlex
- W2087400133
- Cited by
- 688
- References
- 89
- FWCI
- 10.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
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- Pommier, Y., Johnson, A. A., & Marchand, C. (2005). Integrase inhibitors to treat HIV/Aids. Nature Reviews Drug Discovery. https://doi.org/10.1038/nrd1660
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
