The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
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Cites
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Mutations of the BRAF gene in human cancer
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EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
Sarbassov, D. D., Guertin, D. A., Ali, S. M., & Sabatini, D. M. (2005) · Science · doi:10.1126/science.1106148 · Cited by 6,216
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“PTEN activity contributes to the efficacy of trastuzumab (Herceptin; Genentech) and radiation therap”
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Cited by
PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
Glaviano, A., Foo, A. S. C., Lam, H. Y., Yap, K. C. H., Jacot, W., Jones, R. H., Eng, H., Nair, M. G., Makvandi, P., Geoerger, B., et al. (2023) · Molecular Cancer · doi:10.1186/s12943-023-01827-6 · Cited by 2,138
Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation
Balla, T. (2013) · Physiological Reviews · doi:10.1152/physrev.00028.2012 · Cited by 1,638
Hyperactive Ras in developmental disorders and cancer
Schubbert, S., Shannon, K., & Bollag, G. (2007) · Nature Reviews Cancer · doi:10.1038/nrc2109 · Cited by 1,583
Carracedo, A., Ma, L., Teruya-Feldstein, J., Rojo, F., Salmena, L., Alimonti, A., Egia, A., Sasaki, A. T., Thomas, G., Kozma, S. C., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34739 · Cited by 1,381
An integrative genomic and proteomic analysis of pik3ca, pten, and akt mutations in breast cancer.
Stemke-Hale, K., Gonzalez-Angulo, A. M., Lluch, A., Neve, R. M., Kuo, W.-L., Davies, M., Carey, M., Hu, Z., Guan, Y., Sahin, A., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6854 · Cited by 1,054
Self-citation
Metadata
- Authors
- Hennessy, B. T., Smith, D. L., Ram, P. T., Lu, Y., & Mills, G. B.
- Venue
- Nature Reviews Drug Discovery
- Published
- 2005-12
- Volume
- 4
- Issue
- 12
- Pages
- 988-1004
- ISSN
- 1474-1776 (ISSN-L)
- 1474-1784
- OpenAlex
- W2087861588
- Cited by
- 2,185
- References
- 18
- FWCI
- 4.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery. https://app.cochat.ai/papers/10.1038/nrd1902
- The paper
- Hennessy, B. T., Smith, D. L., Ram, P. T., Lu, Y., & Mills, G. B. (2005). Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery. Nature Reviews Drug Discovery. https://doi.org/10.1038/nrd1902
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
