The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Phosphodiesterases in the CNS: targets for drug development
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Family of cAMP-Binding Proteins That Directly Activate Rap1
Kawasaki, H., Springett, G. M., Mochizuki, N., Toki, S., Nakaya, M., Matsuda, M., Housman, D. E., & Graybiel, A. M. (1998) · Science · doi:10.1126/science.282.5397.2275 · Cited by 1,362
Nibuya, M., Nestler, E., & Duman, R. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-07-02365.1996 · Cited by 1,206
Graybiel, A. M. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00593-5 · Cited by 1,051
Lugnier, C. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.07.003 · Cited by 870
HOUSLAY, M. D., & ADAMS, D. R. (2003) · Biochemical Journal · doi:10.1042/bj20021698 · Cited by 763
cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury
Pearse, D. D., Pereira, F. C., Marcillo, A. E., Bates, M. L., Berrocal, Y. A., Filbin, M. T., & Bunge, M. B. (2004) · Nature Medicine · doi:10.1038/nm1056 · Cited by 727
Studies on the Mechanism of Hormone Action
Sutherland, E. W. (1972) · Science · doi:10.1126/science.177.4047.401 · Cited by 687
DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling
Millar, J. K., Pickard, B. S., Mackie, S., James, R., Christie, S., Buchanan, S. R., Malloy, M. P., Chubb, J. E., Huston, E., Baillie, G. S., et al. (2005) · Science · doi:10.1126/science.1112915 · Cited by 648
Keynote review: Phosphodiesterase-4 as a therapeutic target
Houslay, M. D., Schafer, P., & Zhang, K. Y. J. (2005) · Drug Discovery Today · doi:10.1016/s1359-6446(05)03622-6 · Cited by 635
dunce, a mutant of Drosophila deficient in learning.
Dudai, Y., Jan, Y. N., Byers, D., Quinn, W. G., & Benzer, S. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.5.1684 · Cited by 618
Cited by
cGMP Signalling in the Mammalian Brain: Role in Synaptic Plasticity and Behaviour
Kleppisch, T., & Feil, R. (2009) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-540-68964-5_24 · Cited by 161
Andreetta, F., Carboni, L., Grafton, G., Jeggo, R., Whyment, A. D., van den Top, M., Hoyer, D., Spanswick, D., & Barnes, N. M. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13432 · Cited by 28
Grodin, E. N., Nieto, S. J., Meredith, L. R., Burnette, E., O'Neill, J., Alger, J., London, E. D., Miotto, K., Evans, C. J., Irwin, M. R., et al. (2022) · Addiction Biology · doi:10.1111/adb.13182 · Cited by 25
Roflumilast: A potential drug for the treatment of cognitive impairment?
Sugin, L. J. S., Murugesan, A., Bindu, M., & Sunil, K. N. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135281 · Cited by 24
The anti-depressant effects of a novel PDE4 inhibitor derived from resveratrol
Yu, Y., Wang, J., & Huang, X. (2021) · Pharmaceutical Biology · doi:10.1080/13880209.2021.1907422 · Cited by 14
Metadata
- Authors
- Menniti, F. S., Faraci, W. S., & Schmidt, C. J.
- Venue
- Nature Reviews Drug Discovery
- Published
- 2006-08
- Volume
- 5
- Issue
- 8
- Pages
- 660-670
- ISSN
- 1474-1776 (ISSN-L)
- 1474-1784
- OpenAlex
- W2048099169
- Cited by
- 391
- References
- 81
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Phosphodiesterases in the CNS: targets for drug development. https://app.cochat.ai/papers/10.1038/nrd2058
- The paper
- Menniti, F. S., Faraci, W. S., & Schmidt, C. J. (2006). Phosphodiesterases in the CNS: targets for drug development. Nature Reviews Drug Discovery. https://doi.org/10.1038/nrd2058
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.