Glycosylation as a strategy to improve antibody-based therapeutics
DOI 10.1038/nrd2804
Cited by (763)
Items 701–763 of 763
- LC/MS Assessment of Glycoform Clearance of A Biotherapeutic MAb in Rabbit Ocular TissuesShiyu Dong, Linzhi Chen, Achim Sauer, Lars Dittus · 2023 · Journal of Pharmaceutical Sciences
- Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells.M. Marbiah, P. Kotidis, Roberto Donini, Itzcóatl A. Gómez, Ioscani Jiménez del Val, S. Haslam, K. Polizzi, C. Kontoravdi · 2022 · Journal of Visualized Experiments
- Development of a robust bioassay of monoclonal antibodies and biosimilars against TNF-α by NF-κB-inducible lentiviral reporter gene.Jing Huang, Lan Wang, Chuanfei Yu, Zhihao Fu, Chunyu Liu, Gang Wu, Luyun Guo, Xiao Guo, Shiyu Chen, Xumei Liu et al. · 2021 · International Immunopharmacology
- Enzymatic Synthesis of a Fluorogenic Reporter Substrate and the Development of a High-Throughput Assay for Fucosyltransferase VIII Provide a Toolkit to Probe and Inhibit Core FucosylationMaxim Soroko, David H. Kwan · 2020 · Biochemistry
- Functional analysis of recombinant buffalo lactoferrin and monoferric lobes and their cytotoxic effect on buffalo mammary epithelial cellsSurender Singh, Shalini Kalra, Parvesh Bubber, Tirtha Kumar Datta, Ashok Kumar Mohanty, Jai K. Kaushik · 2019 · BioMetals
- HM10660A, a long-acting hIFN-α-2b, is a potent candidate for the treatment of hepatitis C through an enhanced biological half-life.S. Bae, Taehoon Sim, Chaemin Lim, Daejin Kim, Jongsoon Lee, Young-Ju Park, Sungyoub Jung, Inyoung Choi, Sechang Kwon, K. Oh · 2017 · International journal of pharmaceutics
- Antibody Posttranslational ModificationsRoy Jefferis · 2016 · Wiley eBooks
- Biosimilars bei Psoriasis: Was können wir erwarten?M. Radtke, M. Augustin · 2014
- Analytical Methods Used to Characterize Fc‐Fusion ProteinsEsohe Idusogie, M. Mulkerrin · 2013
- Tumours: Targeting of Monoclonal Antibodies for Imaging and Potential for TherapySukhwinder Kaur, Maneesh Jain, Shantibhushan Senapati, Surinder K. Batra · 2012 · Encyclopedia of Life Sciences
- Identification and Quantification of Degradants and Impurities in AntibodiesDavid M. Hambly, Himanshu S. Gadgil · 2011
- Antikörper – neue Krebsmedikamente. Gezielt wirksame BiomedizinMax Hasmann, Christian Klein, Georg‐Burkhard Kresse · 2009 · Chemie in unserer Zeit
- Compartmental Glycosylation Flux AnalysisShilpi Aggarwal, X. Qi, S. Neelamegham, R. Gunawan · 2021 · IFAC-PapersOnLine
- Plant Platform for Therapeutic Monoclonal Antibody ProductionY. Dorokhov, Е. В. Шешукова, T. Komarova · 2019 · Plant Biotechnology
- Role of Glycosylation in Modulating Therapeutic Efficiency of Protein PharmaceuticalsP. A. Dar, Usma Manzoor, S. S. Wani, F. Ali, T. Dar · 2019 · Protein Modificomics
- Synthesis of N-Linked Glycopeptides Using Convergent Enzymatic Glycosylation Combined with SPPSRenata Kowalczyk, Harveen Kaur, Antony J. Fairbanks, Margaret Anne Brimble · 2017 · Springer eBooks
- Metabolic and transcriptomic response to hyperosmotic stimulus reveals strategies for optimization of antibody producing Chinese hamster ovary cellsJennifer Pfizenmaier-Wu · 2017
- Early candidate selection and formulation developmentVladimir I. Razinkov, Gerd R. Kleemann · 2016 · Elsevier eBooks
- A Review on Bioanalytical Methods for Quantifying and Structural Determination of Therapeutic Monoclonal AntibodiesPhanisai Yeminedi, Murali Karthik Jalla, Bhavya Sri Kakarla, Prabhas Palepogu, R. Guntupalli · 2026 · Journal of Pharma Insights and Research
- Plant Molecular Farming for Cancer Immunotherapy: Production, Glycoengineering, and Structural Insights into Therapeutic Monoclonal AntibodiesM. Tamayo-Ordóñez, M. García-Castillo, F. Tamayo-Ordóñez, Víctor de Jesús Suárez-Valencia, A. Córdova-Quiroz, V. H. Ramos-García, B. A. Ayil-Gutiérrez, Á. V. Domínguez-May, S. L. Nahuat-Dzib, J. C. Robles-Heredia et al. · 2026 · Current Issues in Molecular Biology
- Transient Expression of an IL-1Ra-Fc Fusion Cytokine in Tobacco Species for Improved Anti-inflammatory Therapeutic Potential.Anith Kumar Rajendran, Vaishnavi Ashokkumar, T. Krishnaraj, Kalimuthu Karuppanan, Senthilkumar Palanisamy · 2026 · ACS Synthetic Biology
- Rational design of high-productivity perfusion processes for CHO Cells: From growth inhibitory strategies to model-driven optimizationQingyuan Ran, Wen‐Song Tan · 2026 · Journal of Biotechnology
- Glycosylation penetrance of N-X-S/T sequons in antibody variable domains: a structural survey of 19,265 human antibody structures reassessing the histidine/glutamine suppression hypothesisChristopher L. Gaughan · 2026 · mAbs
- Structural Elucidation of Fc- and Fab-Associated N-Glycans in Cetuximab Using Protein A-Assisted Domain-Resolved Glycan Profiling Using Mass Spectrometry.Divya Chauhan, Tarun Shivach, A. Rathore · 2026 · Journal of the American Society for Mass Spectrometry
- Biological Functions of Glycosylation and Their Application in Glycoengineered TherapeuticsCorbyn Kubalek, Spencer Gardiner, William P. Heaps, Kristina M. McCammon, Sam Talcott, Matthew Argyle, Bradley Charles Bundy, Dennis Della Corte · 2026 · ChemEngineering
- Development of single-chain C1q affinity chromatography–mass spectrometry for the glycoform-resolved characterization of low-affinity immunoglobulin G interactionsSteffen Lippold, Kelvin Chang, Mirjam Dürkoop, Jan Terje Andersen, Feng Yang, Tilman Schlothauer · 2026 · mAbs
- Second-generation lectin microarray for high throughput glycan profiling of therapeutic antibodiesKayla A. Hess, Helena Yun, Shen Luo, Uriel Ortega-Rodriguez, Grace Henry Lunde, S. Rogstad, Lai-Xi Wang, Bao-Lin Zhang · 2026 · AAPS Open
- Site-specific enrichment of highly sialylated N-glycans in an erythropoietin–hybrid Fc fusion proteinJuhee Park, Daeun Eom, Chi Soo Park, Chulmin Moon, Siwon Kim, Seojeong Lee, Jihyeon Lee, Jungmi Shin, Youngho Jo, Minji Lee et al. · 2026 · European Journal of Pharmaceutics and Biopharmaceutics
- Engineering nasally delivered IgM antibodies for respiratory viral infectionsAshwin Kumar Ramesh, Zhiqiang An · 2026 · hLife
- N -Glycosylation differences between recombinant and wildtype glycoproteins revealed by mass spectrometryYang Zou, Dario A. T. Cramer, Albert J. R. Heck, Karli R. Reiding · 2026 · Critical Reviews in Biotechnology
- Nucleic acid-assisted metabolic glycan labeling: A promising strategy for enhanced glycoconjugate imaging in cells and in vivoSi-Rui Liu, Meng-Yu Huang, Jin Li, Shu-Lin Wang, Wei Lv, Wanshuang Cao, Bing-Zhi Li, Xing Zhang · 2026 · Trends in Analytical Chemistry (TrAC)
- Integrating text mining and knowledge graph to enhance biopharmaceutical process optimizationShovan Bhowmik, Manju Anandakrishnan, L. Klein, C. Arighi, Marisa Gioioso, Cathy Wu, Austin J. Brockmeier, K. Vijay-Shanker, Chu-Ming Chen · 2026 · PLoS ONE
- Comparative Analysis of Glycan Composition in Therapeutic Antibodies via Glycan Profiling and Intact Mass AnalysisYoun Seo Chun, Jae Beom Lee, Seongin Seomun, S. Y. Park, Jung‐Hyun Na, Byoung Joon Ko · 2025 · Molecules
- Asymmetrical Glyco-Engineering of Monoclonal Antibodies Provides Insights into α-Gal ImmunogenicityGerlof P. Bosman, Anna M. Ehlers, Thomas Buckley, Justyna M. Dobruchowska, Javier Sastre Toraño, Arthur E. H. Bentlage, André C. Knulst, Gestur Vidarsson, Geert‐Jan Boons · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Multiscale Computational Studies of PEG Chain Length Effects on HER2 mAb Fc Structure and Binding EnergeticsHeather A. Noriega, Emmanuel O. Akala, Xiang Simon Wang · 2025 · ACS Omega
- Structure-Based High-Efficiency Homogeneous Antibody Platform by Endoglycosidase Sz Provides Insights into Its Transglycosylation MechanismYin‐Cheng Hsieh, Hong‐Hsiang Guan, Chien-Chih Lin, Teng-Yi Huang, Phimonphan Chuankhayan, Nai-Chi Chen, Nan-Hsuan Wang, Pu-Ling Hu, Yi-Chien Tsai, Yen‐Chieh Huang et al. · 2024 · JACS Au
- Neuronal C-Reactive Protein Mediates Neuropathic Pain by Activating Nociceptive FcγRI-Coupled SignalingFan Liu, Si Su, Li Zhang, Yehong Fang, Huan Cui, Jianru Sun, Yikuan Xie, Chao Ma · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Detecting substrate glycans of fucosyltransferases on glycoproteins with fluorescent fucoseZheng-Liang L. Wu, M. Whitaker, Anthony D. Person, V. Kalabokis · 2020 · bioRxiv
- Genome-editing techniques to increase the therapeutic efficacy of monoclonal antibodiesVictoria Valerievna Firstova, I. G. Shemyakin, Ivan Alekseevich Dyatlov · 2020 · Annals of the Russian academy of medical sciences
- Enzymatic Synthesis of a Fluorogenic Reporter Substrate and a High-Throughput Assay for Fucosyltransferase VIII Provide a Toolkit to Probe and Inhibit Core FucosylationMaxim Soroko, David H. Kwan · 2019
- Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass SpectrometrySiti Nurul Hidayah, M. Gaikwad, Laura Heikaus, H. Schlüter · 2019 · Proteoforms - Concept and Applications in Medical Sciences
- Natural Killer cell subsets in hematological diseases : learning for immunotherapyDang-Nghiem Vo · 2018 · theses.fr (ABES)
- Anticorps monoclonaux en oncologie : déclencher une réponse immunitaire en plus de la réduction tumorale spécifique.Anne‐Gaëlle Goubet, Lisa Derosa, Aurélien Marabelle, Laurence Zitvogel · 2018 · Bulletin de l Académie Nationale de Médecine
- Impact de la modification du métabolisme primaire des cellules CHO sur leur productivitéC. Toussaint · 2017
- Chapter 17 Plant-Based Production of Biosimilar Drug ProductsKenny K. Y. So, Michael R. Marit, Michael D. Mclean, J. C. Hall · 2017
- Human immunosuppressive protein, galectin-1 emerges as a novel regulatory factor in autoimmune disordersÁkos Hornung · 2017
- A simultaneous assessment metric for MAb quantity and glycan qualityGerald Drouillard, Gordon L. Hayward, Julie R. Vale, Roshni L. Dutton · 2016 · Cytotechnology
- Apports de l'échange hydrogène/deutérium couplé à la spectrométrie de masse en protéomique structurale pour la caractérisation de complexes multi-protéiques.Guillaume Terral · 2016 · theses.fr (ABES)
- Etude de l’immunité anti-tumorale à long-terme induite par traitement par un anticorps anti-CD20 de souris porteuses de tumeurClaire Deligne · 2015 · theses.fr (ABES)
- Novel O-glycan arrays to characterize human cancer-associated epithelial antigensChao Gao · 2015
- Functional Glycomics AnalysisNathan W. Stebbins, Ram Sasisekharan · 2014 · Comprehensive analytical chemistry
- The Commercial Development of Antibodies as DrugsM. Eaton, J. Adair · 2011
- Therapeutic Monoclonal Antibodies: Current Perspectives and Applications for the Treatment of Head and Neck CancerStanislas Blein, Sam Hou · 2011 · International Journal of Head and Neck Surgery
- Cases for 3D Cultures in Drug DiscoveryW. Kisaalita · 2010 · CRC Press eBooks
- Monoclonal Antibody Glycoengineering for Biopharmaceutical Quality AssuranceItzcóatl A. Gómez, Ioscani Jiménez del Val · 2021 · Cell engineering
- Eukaryotic Expression Systems for Upstream Processing of Monoclonal AntibodiesLina Heistinger, David Reinhart, Diethard Mattanovich, Renate Kunert · 2020 · Learning materials in biosciences
- Chemo-Enzymatic Syntheses of Oligosaccharides and GlycoconjugatesM. Yamaguchi, Kenji Yamamoto · 2020
- Posttranslational Modification of Heterologous Human Therapeutics in Plant Host Expression SystemsArchana Ayyagari, Lakshna Mahajan, Safikur Rahman, Rinki Minakshi · 2019 · Elsevier eBooks
- Cryogenic infrared spectroscopy as a probe of structure and dynamics of biomoleculesValeriu Scutelnic · 2018
- Protein Conformational Array Technology for Biosimilar Higher Order Structure AnalysisXing Wang, Wen‐Rong Lie, Jehangir Mistry · 2018 · AAPS advances in the pharmaceutical sciences series
- Tumor-Targeted AntibodiesAurélien Marabelle · 2017 · Springer eBooks
- Cryogenic Ion Spectroscopy of Peptides and GlycansChiara Masellis · 2017
- Engineered Antibody Derivatives in Preclinical and Clinical DevelopmentChristian Kellner, Matthias Peipp · 2013 · Springer eBooks