Glycosylation as a strategy to improve antibody-based therapeutics

Jefferis, Roy·2009·Nature Reviews Drug Discovery

DOI 10.1038/nrd2804

Cited by (763)

Items 201–300 of 763

Obinutuzumab in hematologic malignancies: Lessons learned to date
Tim Illidge, Christian Klein, Laurie Helen Sehn, Andrew John Davies, Gilles Andre Salles, Guillaume Cartron · 2015 · Cancer Treatment Reviews
Aglycosylated full-length IgG antibodies: steps toward next-generation immunotherapeutics.
Man-Seok Ju, S. Jung · 2014 · Current Opinion in Biotechnology
Influence of glycosylation pattern on the molecular properties of monoclonal antibodies
Kai Zheng, Mark Yarmarkovich, Christopher Bantog, Robert J. Bayer, Thomas W. Patapoff · 2014 · mAbs
High-throughput work flow for IgG Fc-glycosylation analysis of biotechnological samples
Dietmar Reusch, Markus Haberger, Maurice H. J. Selman, Patrick Bulau, André M. Deelder, Manfred Wuhrer, Niklas Engler · 2012 · Analytical Biochemistry
FUT8 and Protein Core Fucosylation in Tumours: From Diagnosis to Treatment
Chengcheng Liao, Jiaxing An, Suqin Yi, Zhangxue Tan, Hui Wang, Hao Li, Xiaoyan Guan, Jianguo Liu, Qian Wang · 2021 · Journal of Cancer
High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer
Dietmar Reusch, Markus Haberger, Tobias Kailich, Anna-Katharina Heidenreich, Michael Kampe, Patrick Bulau, Manfred Wuhrer · 2013 · mAbs
Developability assessment as an early de-risking tool for biopharmaceutical development
Jesús Zurdo · 2013 · Pharmaceutical Bioprocessing
Glycosylation Shapes the Efficacy and Safety of Diverse Protein, Gene and Cell Therapies
Frances Rocamora, Angelo Gabriel Peralta, Seunghyeon Shin, James Sorrentino, Mina Ying Min Wu, Eric A. Toth, Thomas R. Fuerst, Nathan E. Lewis · 2023 · Biotechnology Advances
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors
D. Sánchez-Martínez, Nerea Allende-Vega, S. Orecchioni, G. Talarico, Amélie Cornillon, Dang-Nghiem Vo, C. René, Zhao-Yang Lu, Ewelina Krzywińska, A. Anel et al. · 2018 · Theranostics
Cell-Free Synthesis Meets Antibody Production: A Review
Marlitt Stech, Stefan Kubick · 2015 · Antibodies
Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals
Fabian Higel, Uwe M. Demelbauer, Andreas Seidl, Wolfgang Frieß, F. Sörgel · 2013 · Analytical and Bioanalytical Chemistry
Is N-acetyl-d-glucosamine a rigid 4C1 chair?
Benedict M. Sattelle, Andrew Almond · 2011 · Glycobiology
Product Quality Considerations for Mammalian Cell Culture Process Development and Manufacturing
Michael J. Gramer · 2013 · Advances in biochemical engineering, biotechnology
IgE immunotherapy: A novel concept with promise for the treatment of cancer
Josephs, Debra H, Spicer, James F, Karagiannis, Panagiotis, Gould, Hannah J, Karagiannis, Sophia N · 2014 · mAbs
Mammalian α-1,6-Fucosyltransferase (FUT8) Is the Sole Enzyme Responsible for the N-Acetylglucosaminyltransferase I-independent Core Fucosylation of High-mannose N-Glycans
Qiang Yang, Lai‐Xi Wang · 2016 · Journal of Biological Chemistry
Glycan Analysis by Reversible Reaction to Hydrazide Beads and Mass Spectrometry
Shuang Yang, Hui Zhang · 2012 · Analytical Chemistry
Fc‐engineered EGF‐R antibodies mediate improved antibody‐dependent cellular cytotoxicity (ADCC) against KRAS ‐mutated tumor cells
Martin Schlaeth, Sven Berger, Stefanie Derer, Katja Klausz, Stefan Lohse, Michael Dechant, Greg A. Lazar, Tanja Schneider‐Merck, Matthias Peipp, Thomas Valerius · 2010 · Cancer Science
Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies
Capucine L. Grandjean, Fabrício Montalvão, Susanna Celli, David Michonneau, Béatrice Bréart, Zacarias Garcia, Mario Perro, Olivier Freytag, Christian A. Gerdes, Philippe Bousso · 2016 · Scientific Reports
Glycosylation of monoclonal antibody products: Current status and future prospects
Jyoti Batra, Anurag Singh Rathore · 2016 · Biotechnology Progress
Biosimilars in IBD: hope or expectation?
K. Gecse, R. Khanna, G. R. van den Brink, C. Ponsioen, M. Lowenberg, V. Jairath, S. Travis, W. Sandborn, B. Feagan, G. D'Haens · 2013 · Gut
Cation exchange surface-mediated denaturation of an aglycosylated immunoglobulin (IgG1).
Ron Gillespie, Thao Nguyen, Sean Macneil, Laurie Jones, Shon Crampton, Suresh Vunnum · 2012 · Journal of Chromatography A
Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC
Roland Repp, Christian Kellner, Anja Muskulus, Matthias Staudinger, Sahar Mohseni Nodehi, Pia Glorius, Dalia Akramienė, Michael Dechant, Georg H. Fey, Patrick H.C. van Berkel et al. · 2011 · Journal of Immunological Methods
Recent advances in the understanding of biological implications and modulation methodologies of monoclonal antibody N‐linked high mannose glycans
Helen H. Shi, C. Goudar · 2014 · Biotechnology and Bioengineering
Rapid High Resolution Characterization of Functionally Important Monoclonal Antibody N-Glycans by Capillary Electrophoresis
Z. Szabó, A. Guttman, J. Bones, B. Karger · 2011 · Analytical Chemistry
Substitution of glutamine by glutamate enhances production and galactosylation of recombinant IgG in Chinese hamster ovary cells
Jong Kwang Hong, Sung Min Cho, Sung Kwan Yoon · 2010 · Applied Microbiology and Biotechnology
Plant glyco-biotechnology on the way to synthetic biology
Andreas Loos, Herta Steinkellner · 2014 · Frontiers in Plant Science
HIV-specific antibody immunity mediated through NK cells and monocytes.
M. Kramski, M. S. Parsons, I. Stratov, S. Kent · 2013 · Current HIV Research
European Medicines Agency workshop on biosimilar monoclonal antibodies
Janice M. Reichert, Alain Beck, Harish V Iyer · 2009 · mAbs
Antibody‐Nanoparticle Conjugates in Therapy: Combining the Best of Two Worlds
Aniruddha Adhikari, Irene A. Chen · 2025 · Small
An oligosaccharyltransferase from Leishmania major increases the N‐glycan occupancy on recombinant glycoproteins produced in Nicotiana benthamiana
Alexandra Castilho, Gernot Beihammer, Christina Pfeiffer, Kathrin Göritzer, Laura Montero‐Morales, Ulrike Vavra, Daniel Maresch, Clemens Grünwald‐Gruber, Friedrich Altmann, Herta Steinkellner et al. · 2018 · Plant Biotechnology Journal
Monoclonal Antibody Therapies for Hematological Malignancies: Not Just Lineage-Specific Targets
Carlos Cuesta‐Mateos, Ana Alcaraz‐Serna, Beatriz Somovilla-Crespo, Cecilia Muñoz‐Calleja · 2018 · Frontiers in Immunology
Host Cell Proteins in Biologics Manufacturing: The Good, the Bad, and the Ugly
Martin Kornecki, Fabian Mestmäcker, Steffen Zobel‐Roos, Laura Heikaus de Figueiredo, Hartmut Schlüter, Jochen Strube · 2017 · Antibodies
A two-step enzymatic glycosylation of polypeptides with complex N-glycans
J. Lomino, A. Naegeli, J. Orwenyo, M. Amin, M. Aebi, Lai-Xi Wang · 2013 · Bioorganic & Medicinal Chemistry
Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry
Steffen Lippold, Simone Nicolardi, Elena Domínguez‐Vega, Anna-Katharina Heidenreich, Gestur Vidarsson, Dietmar Reusch, Markus Haberger, Manfred Wuhrer, David Falck · 2019 · mAbs
The Highly Evolvable Antibody Fc Domain
Hye In Park, Hyun Woung Yoon, Sang Taek Jung · 2016 · Trends in biotechnology
Demonstration of Functional Similarity of Proposed Biosimilar ABP 501 to Adalimumab
J. Velayudhan, Yuh-feng Chen, Amanda S. Rohrbach, Christina Pastula, Gwen Maher, Heather J. Thomas, Ryan Brown, T. Born · 2016 · BioDrugs
Characterization of glycosylation sites for a recombinant IgG1 monoclonal antibody and a CTLA4-Ig fusion protein by liquid chromatography-mass spectrometry peptide mapping.
J. Bongers, John Devincentis, Jinmei Fu, P. Huang, D. Kirkley, K. Leister, Peiran Liu, R. Ludwig, Kathleen Rumney, L. Tao et al. · 2011 · Journal of Chromatography A
miR‐2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality
Simon Fischer, Albert Jesuran Paul, Andreas Wagner, Sven Mathias, Melanie Geiss, Franziska Schandock, Martin Domnowski, Jörg Zimmermann, René Handrick, Friedemann Hesse et al. · 2015 · Biotechnology and Bioengineering
Perspectives for Glyco-Engineering of Recombinant Biopharmaceuticals from Microalgae
Lorenzo Barolo, Raffaela M. Abbriano, Audrey S. Commault, Jestin George, Tim Kahlke, Michele Fabris, Matthew Paul Padula, Angelo Lopez, Peter J. Ralph, Mathieu Pernice · 2020 · Cells
Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies
Ngoc Phuong Lan Le, Thomas A. Bowden, Weston B. Struwe, Max Crispin · 2016 · Biochimica et Biophysica Acta (BBA) - General Subjects
Exploring the Potential of Monoclonal Antibody Therapeutics for HIV-1 Eradication
Zelda Euler, Galit Alter · 2014 · AIDS Research and Human Retroviruses
Systems glycobiology for glycoengineering
Philipp N. Spahn, Nathan E. Lewis · 2014 · Current Opinion in Biotechnology
Control of galactosylated glycoforms distribution in cell culture system
Neil A. McCracken, Ronald L. Kowle, Anli Ouyang · 2014 · Biotechnology Progress
Biological Insights into Therapeutic Protein Modifications throughout Trafficking and Their Biopharmaceutical Applications
Xiaotian Zhong, Jill F. Wright · 2013 · International Journal of Cell Biology
Biopharmaceuticals: an overview
B. Sekhon · 2010 · The Thai Journal of Pharmaceutical Sciences
Perspective of Immunopathogenesis and Immunotherapies for Kawasaki Disease
Lung Chang, Horng‐Woei Yang, Tang-Yu Lin, Kuender D. Yang · 2021 · Frontiers in Pediatrics
A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis
Daniel James Wong, Dayoung Park, Simon Jigwan Park, Carolyn A. Haller, Jiaxuan Chen, Erbin Dai, Liying Liu, Appi Reddy Mandhapati, Pradheep Eradi, Bibek Dhakal et al. · 2021 · Blood
In-Depth Method for the Characterization of Glycosylation in Manufactured Recombinant Monoclonal Antibody Drugs
Ting Song, Sureyya Ozcan, A. Becker, C. Lebrilla · 2014 · Analytical Chemistry
Human IgG1 Hinge Fragmentation as the Result of H2O2-mediated Radical Cleavage
Boxu Yan, Zac Yates, Alain Balland, Gerd R. Kleemann · 2009 · Journal of Biological Chemistry
Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells
Hong, Jong Kwang, Lee, Sang Min, Kim, Kyung-Yong, Lee, Gyun Min · 2014 · Applied Microbiology and Biotechnology
Full-length recombinant antibodies from Escherichia coli : production, characterization, effector function (Fc) engineering, and clinical evaluation
Md Harunur Rashid · 2022 · mAbs
Cytokines in the Immune Microenvironment Change the Glycosylation of IgG by Regulating Intracellular Glycosyltransferases
Yedi Cao, Zhijing Song, Zhendong Guo, Xue Zhao, Yan Qing Gong, Keli Zhao, Chenxue Qu, Youyuan Huang, Yan Li, Ying Gao et al. · 2022 · Frontiers in Immunology
What can mathematical modelling say about CHO metabolism and protein glycosylation?
Sarah N. Galleguillos, David E. Ruckerbauer, Matthias Peter Gerstl, Nicole Borth, Michael Hanscho, Jürgen Zanghellini · 2017 · Computational and Structural Biotechnology Journal
Effect of high mannose glycan pairing on IgG antibody clearance
Diana Liu, Gregory C. Flynn · 2016 · Biologicals
Stabilizing the CH2 domain of an Antibody by Engineering in an Enhanced Aromatic Sequon
Wentao Chen, L. Kong, S. Connelly, Julia M Dendle, Yu Liu, I. A. Grant Wilson, E. Powers, J. Kelly · 2016 · ACS Chemical Biology
Profile of Immunoglobulin G N-Glycome in COVID-19 Patients: A Case-Control Study
Haifeng Hou, Huan Yang, Pengcheng Liu, Changwu Huang, Meng Wang, Yuejin Li, Mingsong Zhu, Jing Wang, Yuan Xu, Youxin Wang et al. · 2021 · Frontiers in Immunology
Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins
Xiaotian Zhong, Weijun Ma, Caryl Meade, Amy Sze Pui Tam, Eliza Llewellyn, Richard J. Cornell, Kaffa Cote, John J. Scarcelli, Jeffrey K. Marshall, Boriana Tzvetkova et al. · 2018 · Biotechnology Progress
A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation
del Val, Ioscani Jimenez, Polizzi, Karen M., Kontoravdi, Cleo · 2016 · Scientific Reports
Galactosyltransferase 4 is a major control point for glycan branching in N-linked glycosylation
Andrew G. McDonald, Jerrard M. Hayes, Tania Bezak, Sonia Agnieszka Gluchowska, Eoin F. J. Cosgrave, Weston B. Struwe, Corné J.M. Stroop, Han J Kok, Teun van de Laar, Pauline Mary Rudd et al. · 2014 · Journal of Cell Science
Monoclonal Antibodies and Toxins—A Perspective on Function and Isotype
Siu-Kei Chow, Arturo Casadevall · 2012 · Toxins
High-throughput profiling of nucleotides and nucleotide sugars to evaluate their impact on antibody N-glycosylation
Thomas K. Villiger, Robert Steinhoff, Marija Ivarsson, Thomas Solacroup, Matthieu Stettler, Hervé Broly, Jasmin Krismer, Martin Pabst, Renato Zenobi, Massimo Morbidelli et al. · 2016 · Journal of Biotechnology
A novel baculovirus vector for the production of nonfucosylated recombinant glycoproteins in insect cells
Hideaki Mabashi‐Asazuma, C.-W. Kuo, Kay‐Hooi Khoo, Donald L. Jarvis · 2013 · Glycobiology
Fcγ receptors enable anticancer action of proapoptotic and immune-modulatory antibodies
Jeong M. Kim, Avi Ashkenazi · 2013 · The Journal of Experimental Medicine
EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity
Stéphane Olivier, Marine Jacoby, Cédric Brillon, Sylvana Bouletreau, Thomas Mollet, Olivier Nerrière, Audrey Angel, Sévérine Danet, Boussad Souttou, Fabienne Guéhenneux et al. · 2010 · mAbs
N-glycosylation profile analysis of Trastuzumab biosimilar candidates by Normal Phase Liquid Chromatography and MALDI-TOF MS approaches
Ivan Sánchez de Melo, Paola Grassi, Francisco Ochoa, Jorge Bolı́var, Francisco Jose Garcia-Cozar, Ma Carmen Durán-Ruiz · 2015 · Journal of Proteomics
Bacterial Glycosidases in Pathogenesis and Glycoengineering
Jonathan Sjögren, Mattias Collin · 2014 · Future Microbiology
An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells
del Val, Ioscani Jimenez, Kyriakopoulos, Sarantos, Polizzi, Karen M., Kontoravdi, Cleo · 2013 · Analytical Biochemistry
Analysis of the landscape of biologically-derived pharmaceuticals in Europe: Dominant production systems, molecule types on the rise and approval trends
Sarantos Kyriakopoulos, Cleo Kontoravdi · 2012 · European Journal of Pharmaceutical Sciences
Cell-free systems for accelerating glycoprotein expression and biomanufacturing
Jasmine M. Hershewe, Weston K. Kightlinger, Michael C. Jewett · 2020 · Journal of Industrial Microbiology & Biotechnology
Emergent Properties of Nanosensor Arrays: Applications for Monitoring IgG Affinity Distributions, Weakly Affined Hypermannosylation, and Colony Selection for Biomanufacturing
Nigel Forest Reuel, Brittany R. Grassbaugh, Sebastian Kruss, J. Zachary Mundy, Cary F. Opel, Adebola O. Ogunniyi, Kamal L. Egodage, Ramon Wahl, Bernhard Helk, Jingqing Zhang et al. · 2013 · ACS Nano
From cell line development to the formulated drug product: The art of manufacturing therapeutic monoclonal antibodies
Stefania C. Carrara, Michael Ulitzka, Julius Grzeschik, Henri Kornmann, Björn M Hock, Harald Kolmar · 2020 · International Journal of Pharmaceutics
Recent Progress in Chemo-Enzymatic Methods for the Synthesis of N-Glycans
Qiang Chao, Yi Ding, Zheng-Hui Chen, Meng-Hai Xiang, Ning Wang, Xiao‐Dong Gao · 2020 · Frontiers in Chemistry
GlycoDeNovo – an Efficient Algorithm for Accurate de novo Glycan Topology Reconstruction from Tandem Mass Spectra
Peng-Yu Hong, Hui Sun, Long Sha, Yi Pu, K. Khatri, Xiang Yu, Yang Tang, Cheng Lin · 2017 · Journal of the American Society for Mass Spectrometry
Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation
Qiang Yang, Yanming An, Shilei Zhu, Roushu Zhang, Chun Mun Loke, John F. Cipollo, Lai‐Xi Wang · 2017 · ACS Chemical Biology
Fc receptors: Cell activators of antibody functions
Carlos Rosales, Eileen Uribe‐Querol · 2013 · Advances in Bioscience and Biotechnology
The role of antibody glycosylation in autoimmune and alloimmune kidney diseases
Anaïs Beyze, Christian Larroque, Moglie Le Quintrec · 2024 · Nature Reviews Nephrology
Modulating antibody effector functions by Fc glycoengineering
Mikel García-Alija, Berre Van Moer, Diego E. Sastre, Tala Azzam, Jonathan J. Du, Beatriz Trastoy, Nico Callewaert, Eric J. Sundberg, Marcelo E. Guerin · 2023 · Biotechnology Advances
Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S
Beatriz Trastoy, Erik H. Klontz, Jared Orwenyo, Alberto Marina, Lai‐Xi Wang, Eric J. Sundberg, Marcelo E. Guerin · 2018 · Nature Communications
Glycoengineering of pertuzumab and its impact on the pharmacokinetic/pharmacodynamic properties
Cheng Luo, Song Chen, Na Xu, Chi Chiu Wang, Wenbo Sai, Wei Zhao, Ying Chun Li, Xiao jing Hu, Hong Tian, Xiang dong Gao et al. · 2017 · Scientific Reports
Reexamining opportunities for therapeutic protein production in eukaryotic microorganisms
Catherine B. Matthews, Chapman M. Wright, Angel Kuo, Noelle Colant, Matthew Westoby, John Christopher Love · 2017 · Biotechnology and Bioengineering
MALDI-MS analysis of sialylated N-glycan linkage isomers using solid-phase two step derivatization method
Henghui Li, Wenjie Gao, Xiaojun Feng, Bi‐Feng Liu, Xin Liu · 2016 · Analytica Chimica Acta
Characterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori)
Minoru Tada, Ken‐ichiro Tatematsu, Akiko Ishii‐Watabe, Akira Harazono, Daisuke Takakura, Noritaka Hashii, Hideki Sezutsu, Nana Kawasaki · 2015 · mAbs
Advances in multifunctional glycosylated nanomaterials: preparation and applications in glycoscience.
Avijit K. Adak, Ben-Yuan Li, Chun-Cheng Lin · 2015 · Carbohydrate Research
Enrichment strategies in glycomics based lung cancer biomarker development
L. Ruhaak, U. Nguyen, Carol Stroble, Sandra L. Taylor, Ayumu Taguchi, S. Hanash, C. Lebrilla, Kyoungmi Kim, S. Miyamoto · 2013 · PROTEOMICS - Clinical Applications
Plant species and organ influence the structure and subcellular localization of recombinant glycoproteins
Elsa Arcalís, Johannes Stadlmann, Thomas Rademacher, Sylvain Marcel, M. Sack, Friedrich Altmann, Eva Stöger · 2013 · Plant Molecular Biology
Glycoengineering Chinese hamster ovary cells: a short history
Donini, Roberto, Haslam, Stuart M., Kontoravdi, Cleo · 2021 · Biochemical Society Transactions
Fast and Automated Characterization of Monoclonal Antibody Minor Variants from Cell Cultures by Combined Protein-A and Multidimensional LC/MS Methodologies
Julien Camperi, Lu Dai, Davy Guillarme, Cinzia Stella · 2020 · Analytical Chemistry
The biodistribution of therapeutic proteins: Mechanism, implications for pharmacokinetics, and methods of evaluation
Kip P. Conner, Siva Charan Devanaboyina, Veena A. Thomas, Dan A. Rock · 2020 · Pharmacology & Therapeutics
Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation
Devesh Radhakrishnan, Anne Skaja Robinson, Babatunde A. Ogunnaike · 2017 · Antibodies
Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines
Yusuke Mimura, Ronan M. Kelly, Louise Unwin, Simone Albrecht, Roy Jefferis, Margaret D Goodall, Yoichi Mizukami, Yuka Mimura‐Kimura, Tsuneo Matsumoto, Hiroshi Ueoka et al. · 2015 · Journal of Immunological Methods
Herpes zoster mRNA vaccine induces superior vaccine immunity over licensed vaccine in mice and rhesus macaques
Lulu Huang, Tongyi Zhao, Weijun Zhao, Andong Shao, Huajun Zhao, Wenxuan Ma, Yingfei Gong, Xianhuan Zeng, Changzhen Weng, Lingling Bu et al. · 2024 · Emerging Microbes & Infections
Advanced glycosidases as ingenious biosynthetic instruments.
Zuzana Mészáros, Pavlína Nekvasilová, P. Bojarová, V. Křen, K. Slámová · 2021 · Biotechnology Advances
NK cell activation and recovery of NK cell subsets in lymphoma patients after obinutuzumab and lenalidomide treatment
Dang-Nghiem Vo, C. Alexia, Nerea Allende-Vega, F. Morschhauser, R. Houot, C. Ménard, K. Tarte, G. Cartron, M. Villalba · 2017 · Oncoimmunology
Predictive glycoengineering of biosimilars using a Markov chain glycosylation model
Philipp N. Spahn, Anders Holmgaard Hansen, Stefan Kol, Bjørn Gunnar Rude Voldborg, Nathan E. Lewis · 2016 · Biotechnology Journal
Comparative study of idursulfase beta and idursulfase in vitro and in vivo
Chihwa Kim, Jinwook Seo, Yo-Kyung Chung, Hyi-Jeong Ji, Jaehyeon Lee, Jongmun Sohn, Byoungju Lee, Eui‐Cheol Jo · 2016 · Journal of Human Genetics
High-Throughput Biophysical Analysis and Data Visualization of Conformational Stability of an IgG1 Monoclonal Antibody (mAb) After Deglycosylation
Mohammad A. Alsenaidy, J. H. Kim, Ranajoy Majumdar, D. Weis, S. Joshi, T. Tolbert, C. Middaugh, D. Volkin · 2013 · Journal of Pharmacy and Science
Sialylation enhancement of CTLA4‐Ig fusion protein in Chinese hamster ovary cells by dexamethasone
Ying Jing, Yueming Qian, Zheng Jian Li · 2010 · Biotechnology and Bioengineering
Engineering novel Lec1 glycosylation mutants in CHO–DUKX cells: Molecular insights and effector modulation of N‐acetylglucosaminyltransferase I
Xiaotian Zhong, Cecilia Cooley, Nilufer P. Seth, Zong Sean Juo, Ella Presman, Nicole Resendes, Ravi A. Kumar, Martin Allen, Lidia Mosyak, Mark Stahl et al. · 2012 · Biotechnology and Bioengineering
Field flow fractionation for assessing neonatal Fc receptor and Fcγ receptor binding to monoclonal antibodies in solution
Joey Pollastrini, Thomas M. Dillon, Pavel V. Bondarenko, Robert Chou · 2011 · Analytical Biochemistry
Microdroplet Ultrafast Reactions Speed Antibody Characterization
Pengyi Zhao, Harsha P. Gunawardena, Xiaoqin Zhong, Richard N. Zare, Hao Chen · 2021 · Analytical Chemistry