Putting chirality to work: the strategy of chiral switches

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Items 101–200 of 644

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8. Asymmetric 18 F-fluorination for applications in positron emission tomography
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9. Identification of Single-Molecule Catecholamine Enantiomers Using a Programmable Nanopore
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10. Enantioselectivity of polysaccharide-based chiral stationary phases in supercritical fluid chromatography using methanol-containing carbon dioxide mobile phases
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13. Single-Enantiomer Drugs
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14. Design and Application of Peptide‐Mimic Phosphonium Salt Catalysts in Asymmetric Synthesis
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15. Induction of Molecular Chirality by Circularly Polarized Light in Cyclic Azobenzene with a Photoswitchable Benzene Rotor
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16. Thermal racemization of biaryl atropisomers
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17. Reversal of elution order for profen acid enantiomers in packed‐column SFC on Chiralpak AD
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18. Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: Differences of bioactivity in the enantiomeric series
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19. Chiral‐Selective Antigen‐Presentation by Supramolecular Chiral Polymer Micelles
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20. Patented Drug Extension Strategies on Healthcare Spending: A Cost-Evaluation Analysis
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21. Switching the enantioselectivity of nanoporous host materials by light
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22. Chirality and Biological Activity
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23. Chirality: An inescapable concept for the pharmaceutical, bio‐pharmaceutical, food, and cosmetic industries
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24. “New Drug” Designations for New Therapeutic Entities: New Active Substance, New Chemical Entity, New Biological Entity, New Molecular Entity
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25. Highly Efficient, Enantioselective Syntheses of ( S )-(+)- and ( R )-(−)-Dapoxetine Starting with 3-Phenyl-1-propanol
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26. Neuronal Growth on l - and d -Cysteine Self-Assembled Monolayers Reveals Neuronal Chiral Sensitivity
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27. Total Synthesis and Biological Investigation of (−)‐Artemisinin: The Antimalarial Activity of Artemisinin Is not Stereospecific
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28. Developments in the Catalytic Asymmetric Synthesis of Agrochemicals and Their Synthetic Importance
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29. Atom-Specific Identification of Adsorbed Chiral Molecules by Photoemission
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30. Desymmetrization of Prochiral Phosphanes Using Derivatives of (−)‐Cytisine
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31. Overview of Chirality and Chiral Drugs
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32. Comprehensive Review on Chiral Stationary Phases in Single-Column Simultaneous Chiral–Achiral HPLC Separation Methods
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33. Circular dichroism in a three-dimensional semiconductor chiral photonic crystal
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34. Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC‐33 Compounds: Promising Neuroprotective Agents Acting as σ1 Receptor Agonists
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35. Separation of racemic compound by nanofibrous composite membranes with chiral selector
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36. Stereochemical facets of clinical β‐blockers: An overview
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37. Mechanism and Origins of Stereoinduction in Natural Cinchona Alkaloid Catalyzed Asymmetric Electrophilic Trifluoromethylthiolation of β-Keto Esters with N-Trifluoromethylthiophthalimide as Electrophilic SCF3 Source
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38. Effect of nelfinavir stereoisomers on coronavirus main protease: Molecular docking, molecular dynamics simulation and MM/GBSA study
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39. Pharmacokinetic and pharmacodynamic characteristics of a new S-amlodipine formulation in healthy Korean male subjects: A randomized, open-label, two-period, comparative, crossover study
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40. Enantiomerization Mechanism of Thalidomide and the Role of Water and Hydroxide Ions
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41. The chiral switch: the development of single enantiomer drugs from racemates.
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42. Development of safer molecules through chirality
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43. De novo design, synthesis and spectroscopic characterization of chiral benzimidazole-derived amino acid Zn(II) complexes: Development of tryptophan-derived specific hydrolytic DNA artificial nuclease agent
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44. Enantiomeric separation of chiral sulfoxides by supercritical fluid chromatography
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45. The Exploration of Chirality for Improved Druggability within the Human Kinome
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46. N -Triflylphosphoramides: highly acidic catalysts for asymmetric transformations
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47. Single-Isomer Drugs
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48. Photofabrication of Superhelix‐Like Patterns on Azobenzene Polymer Films
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49. Gardenifolins A–H, Scalemic Neolignans from Gardenia ternifolia: Chiral Resolution, Configurational Assignment, and Cytotoxic Activities against the HeLa Cancer Cell Line
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50. Chiral inversion of 2-arylpropionyl-CoA esters by human α-methylacyl-CoA racemase 1A (P504S)—a potential mechanism for the anti-cancer effects of ibuprofen
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51. Dielectric Tetramer Nanoresonators Supporting Strong Superchiral Fields for Vibrational Circular Dichroism Spectroscopy
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52. Analytical Characterization of Chiral Drug−Protein Interactions: Comparison between the Optical Biosensor (Surface Plasmon Resonance) Assay and the HPLC Perturbation Method
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53. Organic‐Inorganic Hybrid Materials for Efficient Enantioseparation Using Cellulose 3,5‐Dimethylphenylcarbamate and Tetraethyl Orthosilicate
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54. A hydrogen borrowing annulation strategy for the stereocontrolled synthesis of saturated aza-heterocycles
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55. Crystallization of Chiral Molecules
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56. Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases
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57. Enantiomeric fraction as an indicator of pharmaceutical biotransformation during wastewater treatment and in the environment – a review
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58. Novel enantioselective strong cation exchangers based on sulfodipeptide selectors: Evaluation for enantiomer separation of chiral bases by nonaqueous capillary electrochromatography
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59. Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp
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60. Enantiomeric resolution of 2‐arylpropionic acid nonsteroidal anti‐inflammatory drugs by capillary electrophoresis: Methods and applications
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61. Chiral Organophosphorus Pharmaceuticals: Properties and Application
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62. Chirality, a neglected physico-chemical property of nanomaterials? A mini-review on the occurrence and importance of chirality on their toxicity
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63. Photoracemization‐Based Viedma Ripening of a BINOL Derivative
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64. A Highly Enantioselective Copper/Phosphoramidite‐Thioether‐Catalyzed Diastereodivergent 1,3‐Dipolar Cycloaddition of Azomethine Ylides and Nitroalkenes
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65. Probability rule for chiral recognition
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66. Chiral Recognition of Lipid Bilayer Membranes by Supramolecular Assemblies of Peptide Amphiphiles
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67. Inside the isomers: the tale of chiral switches
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68. Enantiomeric Virus-Inspired Oncolytic Particles for Efficient Antitumor Immunotherapy
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69. Stereodivergent Construction of 3,3′-Disubstituted Oxindoles via One-Pot Sequential Allylation/Alkylation and Its Application to the Total Synthesis of Trigolute B and D
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70. Chiral Phenomena in Multinuclear and Metallosupramolecular Coordination Systems Derived from Metalloligands with Thiol-Containing Amino Acids
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71. Organocatalytic Higher-Order [8+2] Cycloaddition for the Assembly of Atropoenantiomeric 3-Arylindolizines
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72. Immobilized polysaccharide derivatives: chiral packing materials for efficient HPLC resolution
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73. Highly Enantioselective Synthesis of 2,3-Dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-ones via Catalytic Asymmetric Intramolecular Cascade Imidization–Nucleophilic Addition–Lactamization
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75. Pre-Concentration Approaches Combined with Capillary Electrophoresis in Bioanalysis of Chiral Cardiovascular Drugs
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76. Ecotoxicological properties of ketoprofen and the S(+)-enantiomer (dexketoprofen): Bioassays in freshwater model species and biomarkers in fish PLHC-1 cell line
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77. Tackling Stereochemistry in Drug Molecules with Vibrational Optical Activity
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78. Ir and NHC Dual Chiral Synergetic Catalysis: Mechanism and Stereoselectivity in γ-Butyrolactone Formation
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79. Circular Dichroism Control of Tungsten Diselenide (WSe2) Atomic Layers with Plasmonic Metamolecules
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80. Ruthenium‐Catalyzed Highly Chemoselective Hydrogenation of Aldehydes
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81. The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies
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82. Optimization of the liquid chromatography enantioseparation of chiral acidic compounds using cellulose tris(3-chloro-4-methylphenylcarbamate) as chiral selector and polar organic mobile phases
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84. The Quest for Secondary Pharmaceuticals: Drug Repurposing/Chiral-Switches Combination Strategy
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85. The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously
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86. Macrocyclic Chiral Receptors toward Enantioselective Recognition of Naproxen
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88. Enhanced Circular Dichroism for Achiral Sensing Based on a DNA-Origami-Empowered Anapole Metasurface
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90. Does Chirality Matter?
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91. Stereochemical Sensitivity of the Human UDP-glucuronosyltransferases 2B7 and 2B17
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92. Highly enantioselective synthesis of dihydroquinazolinones through Sc(OTf)3-catalyzed intramolecular amidation of imines
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95. Molecular model for chirality phenomena
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96. Pyramidal inversion mechanism of simple chiral and achiral sulfoxides: A theoretical study
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97. Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications
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98. Recent Advances on Catalytic Atroposelective Synthesis of Planar‐Chiral Macrocycles
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99. Biomimetic Modelling of Copper Enzymes: Synthesis, Characterization, EPR Analysis and Enantioselective Catalytic Oxidations by a New Chiral Trinuclear Copper(II) Complex
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100. The Novel Mnk1/2 Degrader and Apoptosis Inducer VNLG-152 Potently Inhibits TNBC Tumor Growth and Metastasis
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