The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.
Horizontal gene transfer in eukaryotic evolution
Abstract
Horizontal gene transfer (HGT; also known as lateral gene transfer) has had an important role in eukaryotic genome evolution, but its importance is often overshadowed by the greater prevalence and our more advanced understanding of gene transfer in prokaryotes. Recurrent endosymbioses and the generally poor sampling of most nuclear genes from diverse lineages have also complicated the search for transferred genes. Nevertheless, the number of well-supported cases of transfer from both prokaryotes and eukaryotes, many with significant functional implications, is now expanding rapidly. Major recent trends include the important role of HGT in adaptation to certain specialized niches and the highly variable impact of HGT in different lineages.
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“In multicellular lineages, convincing cases of HGT are rarer but include gene acquisitions in bdelloid rotifers, fungi, and even vertebrate genomes [33,34].”
From Origin and Evolution of Genes in Eukaryotes: Mechanisms, Dynamics, and Functional Implications (2025) · cites this paper as [33]
Citations
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Leliaert, F., Smith, D. R., Moreau, H., Herron, M. D., Verbruggen, H., Delwiche, C. F., & Clerck, O. D. (2012) · Critical Reviews in Plant Sciences · doi:10.1080/07352689.2011.615705 · Cited by 948
Biochemistry and Evolution of Anaerobic Energy Metabolism in Eukaryotes
Müller, M., Mentel, M., van Hellemond, J. J., Henze, K., Woehle, C., Gould, S. B., Yu, R.-Y., van der Giezen, M., Tielens, A. G. M., & Martin, W. F. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05024-11 · Cited by 838
Origins, evolution, and phenotypic impact of new genesPreprint
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Metadata
- Authors
- Keeling, P. J., & Palmer, J. D.
- Affiliations
- University of British Columbia (CA)
- Indiana University Bloomington (US)
- Corresponding author
- Keeling, Patrick J.
- Venue
- Nature Reviews Genetics
- Published
- 2008-08
- Volume
- 9
- Issue
- 8
- Pages
- 605-618
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2055758623
- Cited by
- 1,355
- References
- 159
- Citations by year
- 2026: 54 · 2025: 53 · 2024: 63 · 2023: 91 · 2022: 81 · 2021: 76 · 2020: 76 · 2019: 85 · 2018: 65 · 2017: 70 · 2016: 90 · 2015: 86 · 2014: 82 · 2013: 100 · 2012: 81
- FWCI
- 5.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Genetics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Lilly Endowment
- Canadian Institute for Advanced Research
- Tula Foundation
- National Institutes of Health
- Natural Sciences and Engineering Research Council of Canada
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Protist diversity and phylogeny
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Keywords
- horizontal gene transfer, eukaryotic evolution, genome evolution, endosymbiosis, eukaryotic lineages
- MeSH terms
- Adaptation, Biological, Animals, DNA Transposable Elements, Eukaryotic Cells, Biological Evolution, Humans, Models, Biological, Phylogeny, Plants, Prokaryotic Cells, Symbiosis, Genome, Protein Transport, Gene Transfer, Horizontal
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