The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The impact of retrotransposons on human genome evolution
Open accessAbstract
Their ability to move within genomes gives transposable elements an intrinsic propensity to affect genome evolution. Non-long terminal repeat (LTR) retrotransposons — including LINE-1, Alu and SVA elements — have proliferated over the past 80 million years of primate evolution and now account for approximately one-third of the human genome. In this Review, we focus on this major class of elements and discuss the many ways that they affect the human genome: from generating insertion mutations and genomic instability to altering gene expression and contributing to genetic innovation. Increasingly detailed analyses of human and other primate genomes are revealing the scale and complexity of the past and current contributions of non-LTR retrotransposons to genomic change in the human lineage.
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Cites
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Ten things you should know about transposable elements
Bourque, G., Burns, K. H., Gehring, M., Gorbunova, V., Seluanov, A., Hammell, M., Imbeault, M., Izsvák, Z., Levin, H. L., Macfarlan, T. S., et al. (2018) · Genome Biology · doi:10.1186/s13059-018-1577-z · Cited by 1,430
Targeting p53 pathways: mechanisms, structures, and advances in therapy
Wang, H., Guo, M., Wei, H., & Chen, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01347-1 · Cited by 1,016
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Malhotra, D., & Sebat, J. (2012) · Cell · doi:10.1016/j.cell.2012.02.039 · Cited by 854
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Metadata
- Authors
- Cordaux, R., & Batzer, M. A.
- Venue
- Nature Reviews Genetics
- Published
- 2009-10
- Volume
- 10
- Issue
- 10
- Pages
- 691-703
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2051541780
- Cited by
- 1,703
- References
- 13
- FWCI
- 8.47
- Type
- journal article
- Language
- en
- Open access
- green
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