The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Cleft lip and palate: understanding genetic and environmental influences
Open accessAbstract
Clefts of the lip and/or palate (CLP) are common birth defects of complex aetiology. CLP can occur in isolation or as part of a broad range of chromosomal, Mendelian or teratogenic syndromes. Although there has been marked progress in identifying genetic and environmental triggers for syndromic CLP, the aetiology of the more common non-syndromic (isolated) forms remains poorly characterized. Recently, using a combination of epidemiology, careful phenotyping, genome-wide association studies and analysis of animal models, several distinct genetic and environmental risk factors have been identified and confirmed for non-syndromic CLP. These findings have advanced our understanding of developmental biology and created new opportunities for clinical translational research.
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Cites
Exome sequencing identifies the cause of a mendelian disorder
Ng, S. B., Buckingham, K. J., Lee, C., Bigham, A. W., Tabor, H. K., Dent, K. M., Huff, C. D., Shannon, P. T., Jabs, E. W., Nickerson, D. A., et al. (2010) · Nature Genetics · doi:10.1038/ng.499 · Cited by 1,957
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
Roessler, E., Belloni, E., Gaudenz, K., Jay, P., Berta, P., Scherer, S. W., Tsui, L.-C., & Muenke, M. (1996) · Nature Genetics · doi:10.1038/ng1196-357 · Cited by 1,152
Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing
Roach, J. C., Glusman, G., Smit, A. F. A., Huff, C. D., Hubley, R., Shannon, P. T., Rowen, L., Pant, K. P., Goodman, N., Bamshad, M., et al. (2010) · Science · doi:10.1126/science.1186802 · Cited by 1,084
Rare Variants Create Synthetic Genome-Wide Associations
Dickson, S. P., Wang, K., Krantz, I., Hakonarson, H., & Goldstein, D. B. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000294 · Cited by 857
Whole-Genome Sequencing in a Patient with Charcot–Marie–Tooth Neuropathy
Lupski, J. R., Reid, J. G., Gonzaga-Jauregui, C., Rio Deiros, D., Chen, D. C. Y., Nazareth, L., Bainbridge, M., Dinh, H., Jing, C., Wheeler, D. A., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0908094 · Cited by 759 · cited 1×
“Whole-exome sequencing has recently been successful in identifying causative genetic variants for Mendelian trait”
Genomic views of distant-acting enhancers
Visel, A., Rubin, E. M., & Pennacchio, L. A. (2009) · Nature · doi:10.1038/nature08451 · Cited by 610
Clinical and molecular genetics of Stickler syndrome
Snead, M. P., & Yates, J. R. W. (1999) · Journal of Medical Genetics · doi:10.1136/jmg.36.5.353 · Cited by 448
Mutations in the Human Sterol Δ7-Reductase Gene at 11q12-13 Cause Smith-Lemli-Opitz Syndrome
Wassif, C. A., Maslen, C., Kachilele-Linjewile, S., Lin, D., Linck, L. M., Connor, W. E., Steiner, R. D., & Porter, F. D. (1998) · The American Journal of Human Genetics · doi:10.1086/301936 · Cited by 418
Cited by
Genetics of Nonsyndromic Orofacial Clefts
Rahimov, F., Jugessur, A., & Murray, J. C. (2012) · The Cleft Palate Craniofacial Journal · doi:10.1597/10-178 · Cited by 295
Self-citationYu, Y., Zuo, X., He, M., Gao, J., Fu, Y., Qin, C., Meng, L., Wang, W., Song, Y., Cheng, Y., et al. (2017) · Nature Communications · doi:10.1038/ncomms14364 · Cited by 264
Self-citationInsights into the genetic architecture of the human face
White, J. D., Indencleef, K., Naqvi, S., Eller, R. J., Hoskens, H., Roosenboom, J., Lee, M. K., Li, J., Mohammed, J., Richmond, S., et al. (2021) · Nature Genetics · doi:10.1038/s41588-020-00741-7 · Cited by 166
Self-citationBebee, T. W., Park, J. W., Sheridan, K. I., Warzecha, C. C., Cieply, B. W., Rohacek, A. M., Xing, Y., & Carstens, R. P. (2015) · eLife · doi:10.7554/elife.08954 · Cited by 161
High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development
Wilderman, A., VanOudenhove, J., Kron, J., Noonan, J. P., & Cotney, J. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.03.129 · Cited by 139
Metadata
- Authors
- Dixon, M. J., Marazita, M. L., Beaty, T. H., & Murray, J. C.
- Venue
- Nature Reviews Genetics
- Published
- 2011-02-18
- Volume
- 12
- Issue
- 3
- Pages
- 167-178
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2088287802
- Cited by
- 1,984
- References
- 8
- FWCI
- 7.45
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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