The telomere syndromes
Armanios, Mary, Blackburn, Elizabeth H.·2012·Nature Reviews Genetics
DOI 10.1038/nrg3246
Cited by (975)
Items 201–300 of 975
- High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platformCheng Yong Tham, Lai-Fong Poon, Tingdong Yan, Javier Yu Peng Koh, Muhammad Khairul Ramlee, Vania Swee Imm Teoh, Suihan Zhang, Yi Cai, Zebin Hong, Gina S. Lee et al. · 2023 · Nature Communications
- Is telomere length a molecular marker of past thermal stress in wild fish?Paul V. Debes, Marko Visse, Bineet Panda, Petteri Ilmonen, Anti Vasemägi · 2016 · Molecular Ecology
- Pulmonary phenotypes associated with genetic variation in telomere-related genesThijs W. Hoffman, Coline H.M. van Moorsel, Raphaël Borie, Bruno Crestani · 2018 · Current Opinion in Pulmonary Medicine
- Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of TelomeresCaitlin M. Roake, Steven E. Artandi · 2017 · Cold Spring Harbor Perspectives in Medicine
- The Gut Microbiome, Metformin, and AgingSri Nitya Reddy Induri, Payalben Kansara, Scott C. Thomas, Fangxi Xu, Deepak B. Saxena, Xin Li · 2021 · The Annual Review of Pharmacology and Toxicology
- The role of telomeres and vitamin D in cellular aging and age-related diseasesIrene Pusceddu, Christopher-John Lancaster Farrell, Angela Maria Di Pierro, Erika Jani, Wolfgang Herrmann, Markus Herrmann · 2015 · Clinical Chemistry and Laboratory Medicine (CCLM)
- Genome wide association and linkage analyses identified three loci—4q25, 17q23.2, and 10q11.21—associated with variation in leukocyte telomere length: the Long Life Family StudyJoseph Hyungwoo Lee, Rong Cheng, Lawrence S. Honig, Mary Furlan Feitosa, Candace M. Kammerer, Min Suk Kang, Nicole Schupf, Shiow J. Lin, Jason Leigh Sanders, Harold T. Bae et al. · 2014 · Frontiers in Genetics
- A Possible New Mechanism in the Pathophysiology of Polycystic Ovary Syndrome (PCOS): The Discovery That Leukocyte Telomere Length Is Strongly Associated With PCOSQiaoli Li, Jing Du, Ruizhi Feng, Yao Xu, Haojue Wang, Qing Sang, Qinghe Xing, Xinzhi Zhao, Jin Li, Lin He et al. · 2013 · The Journal of Clinical Endocrinology & Metabolism
- Current Insights to Regulation and Role of Telomerase in Human DiseasesMert B. Ozturk, Yinghui Li, Vinay Tergaonkar · 2017 · Antioxidants
- Acquired and germline predisposition to bone marrow failure: Diagnostic features and clinical implicationsMichael Edward Kallen, Alina Dulau‐Florea, Weixin Wang, Katherine R. Calvo · 2018 · Seminars in Hematology
- Change in Leukocyte Telomere Length Predicts Mortality in Patients with Stable Coronary Heart Disease from the Heart and Soul StudySarah E. Goglin, Ramin Farzaneh‐Far, Elissa S. Epel, Jue Lin, Elizabeth Helen Blackburn, Mary A. Whooley · 2016 · PLoS ONE
- The Spectrum of Hepatic Involvement in Patients With Telomere DiseaseDevika Kapuria, Gil Ben Yakov, Rebecca Ortolano, Min Ho Cho, Or Kalchiem‐Dekel, Varun K. Takyar, Shilpa Lingala, Naveen Gara, Michele May-Sien Tana, Yun Ju Kim et al. · 2019 · Hepatology
- Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombinationTianpeng Zhang, Zepeng Zhang, Gong Shengzhao, Xiaocui Li, Haiying Liu, Yong Bo Zhao · 2019 · PLoS Genetics
- T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to squamous cancersKristen E. Schratz, Diane A. Flasch, Christine C. Atik, Zoe L. Cosner, Amanda L. Blackford, Wentao Yang, Dustin L. Gable, Paz J. Vellanki, Zhimin Xiang, Valeriya A. Gaysinskaya et al. · 2023 · Cancer Cell
- Triallelic and epigenetic-like inheritance in human disorders of telomeraseLaura C. Collopy, Amanda J. Walne, Shirleny Romualdo Cardoso, Josu de la Fuente, Mahfuzah Mohamed, Helga V. Toriello, Hannah Tamary, Adam J. Y. V. Ling, Timothy Lloyd, Rebecca Kassam et al. · 2015 · Blood
- Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesisGrace Shim, Michelle Ricoul, William M. Hempel, Edouard I. Azzam, Laure Sabatier · 2014 · Mutation Research/Reviews in Mutation Research
- Spermatozoa telomeres determine telomere length in early embryos and offspringCelia de Frutos, Angela Patricia López‐Cardona, Noelia Fonseca Balvís, Ricardo Laguna‐Barraza, Dimitrios V. Rizos, Alfonso Gutiérrez‐Adán, Pablo Bermejo‐Álvarez · 2015 · Reproduction
- Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in cultureHulda R. Jónsdóttir, Ari Jón Arason, Ragnar Pálsson, Sigríður Rut Franzdóttir, Tómas Guðbjartsson, Helgi J. Ísaksson, Gunnar Gudmundsson, Þórarinn Guðjónsson, Magnús K. Magnússon · 2015 · Laboratory Investigation
- Evolutionary ecology of telomeres: a reviewMats M. Olsson, Erik Wapstra, Christopher R. Friesen · 2017 · Annals of the New York Academy of Sciences
- Hypo- and Hyper-Assembly Diseases of RNA–Protein ComplexesSiddharth Shukla, Roy Parker · 2016 · Trends in Molecular Medicine
- Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPsSamantha L. Sanford, Griffin A. Welfer, Bret Freudenthal, Patricia Lynn Opresko · 2020 · Nature Communications
- The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to TelomeresAmanda K. Frank, Duy Cong Tran, Roy W. Qu, Bradley A. Stohr, David Jay Segal, Lifeng Xu · 2015 · PLoS Genetics
- Is Chronic Asthma Associated with Shorter Leukocyte Telomere Length at Midlife?Daniel W. Belsky, Idan Shalev, Malcolm R. Sears, Robert John Hancox, Hona Lee Harrington, Renate Houts, Terrie E. Moffitt, Karen Sugden, Benjamin S. Williams, Richie Poulton et al. · 2014 · American Journal of Respiratory and Critical Care Medicine
- Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac agingYingmei Zhang, Cong Wang, Jingmin Zhou, Aijun Sun, Lindsay K. Hueckstaedt, Junbo Ge, Jun Tao Ren · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Aberrant telomere length and mitochondrial DNA copy number in suicide completersIkuo Otsuka, Takeshi Izumi, Shuken Boku, Atsushi Kimura, Yuan Zhang, Kentaro Mouri, Satoshi Okazaki, Kyoichi Shiroiwa, Motonori Takahashi, Yasuhiro Ueno et al. · 2017 · Scientific Reports
- p53 downregulates the Fanconi anaemia DNA repair pathwayJaber, Sara, Toufektchan, Eléonore, Lejour, Vincent, Bardot, Boris, Toledo, Franck · 2016 · Nature Communications
- Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivoDarian D. Cash, Osnat Cohen-Zontag, Nak‐Kyoon Kim, Kinneret Shefer, Yogev Brown, Nikolai B. Ulyanov, Yehuda Tzfati, Juli F. Feigon · 2013 · Proceedings of the National Academy of Sciences
- The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiaeEvan P. Hass, David C. Zappulla · 2015 · eLife
- Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis CongenitaDong‐Hun Woo, Qijun Chen, Ting-Lin Yang, M. Rebecca Glineburg, Carla Hoge, Nicolae Adrian Leu, F Brad Johnson, Christopher J. Lengner · 2016 · Cell stem cell
- Telomerase treatment prevents lung profibrotic pathologies associated with physiological agingPiñeiro-Hermida, Sergio, Autilio, Chiara, Martínez, Paula, Bosch, Fátima, Pérez-Gil, Jesús, Blasco, Maria A. · 2020 · Journal of Cell Biology
- Interactions of the Human Telomere Sequence with the Nanocavity of the α-Hemolysin Ion Channel Reveal Structure-Dependent Electrical Signatures for Hybrid FoldsNa An, Aaron M. Fleming, Cynthia J. Burrows · 2013 · Journal of the American Chemical Society
- Capturing epidermal stemness for regenerative medicineYann Barrandon, Nicolas Grasset, Andrea Zaffalon, François Gorostidi, Stéphanie Claudinot, Stéphanie Lathion Droz-Georget, Daisuke Nanba, Ariane Rochat · 2012 · Seminars in Cell and Developmental Biology
- Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafishKirsten Lex, Mariana Maia-Gil, Bruno Lopes-Bastos, Margarida Figueira, Marta Marzullo, Kety Giannetti, Tânia Carvalho, Miguel Godinho Ferreira · 2020 · Proceedings of the National Academy of Sciences
- Cell-based therapy for idiopathic pulmonary fibrosisQi Lu, Ahmed H. K. El-Hashash · 2019 · Stem Cell Investigation
- Premature aging disorders: A clinical and genetic compendiumFranziska Schnabel, Uwe Kornak, Bernd Wollnik · 2020 · Clinical Genetics
- Telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general populationAndrea Baragetti, Jutta Palmen, Katia Garlaschelli, Liliana Grigore, Fabio Pellegatta, Elena Tragni, Alberico Luigi Catapano, Steve Eric Humphries, Giuseppe Danilo Norata, Philippa J. Talmud · 2014 · Journal of Internal Medicine
- Telomerase and the Genetics of Emphysema Susceptibility. Implications for Pathogenesis Paradigms and Patient CareSusan E. Stanley, Samantha Jean Merck, Mary Y. Armanios · 2016 · Annals of the American Thoracic Society
- NHP2 deficiency impairs rRNA biogenesis and causes pulmonary fibrosis and Høyeraal–Hreidarsson syndromeManame Benyelles, Marie-Françoise O’Donohue, Laëtitia Kermasson, Élodie Lainey, Raphaël Borie, Chantal Lagresle‐Peyrou, Hilario Nunès, Clarisse Cazelles, Cécile Fourrage, Emmanuelle Ollivier et al. · 2020 · Human Molecular Genetics
- Human telomerase specialization for repeat synthesis by unique handling of primer‐template duplexR. Alex Wu, Kathleen Collins · 2014 · The EMBO Journal
- Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cellsHyeung Kim, Feng Li, Quanyuan He, Tingting Deng, Jun Qiang Xu, Feng Jin, Cristian Coarfa, Nagireddy Putluri, Dan Liu, Zhou Songyang · 2017 · Cell Discovery
- Shorter telomere length in schizophrenia: Evidence from a real-world population and meta-analysis of most recent literaturePatrizia Russo, Giulia Prinzi, Stefania Proietti, Palma Lamonaca, Alessandra Frustaci, Stefania Boccia, Rosarita Amore, Maria Lorenzi, Graziano Onder, Emanuele Marzetti et al. · 2018 · Schizophrenia Research
- Emerging roles of CST in maintaining genome stability and human diseaseJ. Stewart, Yi-Lin Wang, Stephanie M. Ackerson, P. L. Schuck · 2018 · Frontiers in Bioscience
- Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive DiapauseBree Heestand, Matt Simon, Stephen Frenk, Denis Titov, Shawn Cameron Ahmed · 2018 · Cell Reports
- TIN2 Functions with TPP1/POT1 To Stimulate Telomerase ProcessivityAlexandra M. Pike, Margaret A. Strong, John Paul T. Ouyang, Carla J. Connelly, Carol W. Greider · 2019 · Molecular and Cellular Biology
- The ‘Jekyll and Hyde’ of Gluconeogenesis: Early Life Adversity, Later Life Stress, and Metabolic DisturbancesSnehaa V. Seal, Jonathan D. Turner · 2021 · International Journal of Molecular Sciences
- Telomere and telomerase in chronic liver disease and hepatocarcinomaLucia Carulli · 2014 · World Journal of Gastroenterology
- SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1 Tpp1 to modulate shelterin–Stn1 interaction in fission yeastKeisuke Miyagawa, Ross S. Low, Venny Santosa, Hiroki Tsuji, Bettina A. Moser, Shiho Fujisawa, Jennifer L. Harland, Olga N. Raguimova, Andrew Go, Masaru Ueno et al. · 2014 · Proceedings of the National Academy of Sciences
- The longitudinal relationship between cortisol responses to mental stress and leukocyte telomere attritionAndrew Steptoe, Mark Hamer, Jue Lin, Elizabeth Helen Blackburn, Jorge D. Erusalimsky · 2016 · The Journal of Clinical Endocrinology & Metabolism
- Predictive factors and prognostic effect of telomere shortening in pulmonary fibrosisLurdes Planas‐Cerezales, Elena G. Arias‐Salgado, Ivette Buendía-Roldán, Ana Montes‐Worboys, Cristina Esquinas, Vanesa Vicens‐Zygmunt, Patricio Luburich Hernáiz, Roger Llatjós Sanuy, Virginia Leiro‐Fernández, Eva Balcells et al. · 2018 · Respirology
- Estimation of environmental, genetic and parental age at conception effects on telomere length in a wild mammalSil H. J. van Lieshout, Alexandra M. Sparks, Amanda J. Bretman, Chris Newman, Christina Dagmar Buesching, Terry A. Burke, David Whyte Macdonald, Hannah L. Dugdale · 2020 · Journal of Evolutionary Biology
- The Genetic and Epigenetic Footprint in Idiopathic Pulmonary Fibrosis and Familial Pulmonary Fibrosis: A State-of-the-Art ReviewClaudio Tirelli, Chiara Pesenti, Monica Rosa Miozzo, Michele Mondoni, Laura Fontana, Stefano Centanni · 2022 · Diagnostics
- Regulatory mechanisms and clinical manifestations of musculoskeletal agingCaleb W. Grote, Daniel Reinhardt, Mingcai Zhang, Jinxi Wang · 2019 · Journal of Orthopaedic Research®
- G-Quadruplex (G4) Motifs in the Maize (Zea mays L.) Genome Are Enriched at Specific Locations in Thousands of Genes Coupled to Energy Status, Hypoxia, Low Sugar, and Nutrient DeprivationCarson M. Andorf, Mykhailo Kopylov, Drena L Dobbs, Karen E. Koch, M. Elizabeth Stroupe, Carolyn J. Lawrence‐Dill, Hank W. Bass · 2014 · Journal of genetics and genomics/Journal of Genetics and Genomics
- A Genome-Wide Association Study Identifies a Locus on TERT for Mean Telomere Length in Han ChineseYun Liu, Lan Cao, Zhiqiang Li, Daizhan Zhou, Wanqing Liu, Qin Shen, Yanting Wu, Dan Zhang, Xun Hu, Ting Wang et al. · 2014 · PLoS ONE
- Validation of Minimally-Invasive Sample Collection Methods for Measurement of Telomere LengthStephanie A. Stout, Jue Lin, Natalie Hernandez, Elysia Poggi Davis, Elizabeth Helen Blackburn, Judith Carroll, Laura M. Glynn · 2017 · Frontiers in Aging Neuroscience
- HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesisTingdong Yan, Wen Fong Ooi, Aditi Qamra, Alice Man Sze Cheung, Dongliang Ma, Gopinath Meenakshi Sundaram, Chang Xu, Manjie Xing, Lai-Fong Poon, Jing Wang et al. · 2018 · Nature Communications
- Peripheral telomere length and hippocampal volume in adolescents with major depressive disorderHenje Blom, E, Han, L K M, Connolly, C G, Ho, T C, Lin, J, LeWinn, K Z, Simmons, A N, Sacchet, M D, Mobayed, N, Luna, M E et al. · 2015 · Translational Psychiatry
- Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodiesJacob M. Vogan, Xiaozhu Zhang, Daniel T. Youmans, Samuel G. Regalado, Joshua Z Johnson, Dirk F. Hockemeyer, Kathleen Collins · 2016 · eLife
- Telomere shortening activates TGF-β/Smads signaling in lungs and enhances both lipopolysaccharide and bleomycin-induced pulmonary fibrosisYingying Liu, Yao Shi, Ya Liu, Xinghua Pan, Kexiong Zhang · 2018 · Acta Pharmacologica Sinica
- Role for Telomerase in Pulmonary HypertensionNathalie Mouraret, Amal Houssaïni, Shariq Abid, Rozenn Anne Quarck, Élisabeth Marcos, Aurelien Parpaleix, Guillaume Gary‐Bobo, Jean‐Luc Dubois‐Randé, Geneviève Dérumeaux, Jorge Boczkowski et al. · 2014 · Circulation
- Over-Expression of Telomere Binding Factors (TRF1 & TRF2) in Renal Cell Carcinoma and Their Inhibition by Using SiRNA Induce Apoptosis, Reduce Cell Proliferation and Migration InvitroDeeksha Pal, Ujjawal Sharma, Shrawan Kumar Singh, Nandita Kakkar, Rajendra Prasad · 2015 · PLoS ONE
- CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere lengthPeili Gu, Shuting Jia, Taylor Takasugi, Eric M. Smith, Jayakrishnan Nandakumar, Eric A. Hendrickson, Sandy S. Chang · 2018 · Aging Cell
- Evaluation and Management of Hematopoietic Failure in Dyskeratosis CongenitaSuneet Agarwal · 2018 · Hematology/Oncology Clinics of North America
- Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere ElongationLü Chen, Caitlin M. Roake, Alessandra Galati, Francesca Bavasso, Emanuela Micheli, Isabella Saggio, Stefan Schoeftner, Stefano Cacchione, Maurizio Gatti, Steven E. Artandi et al. · 2020 · Cell Reports
- Physical activity, a modulator of aging through effects on telomere biologyMaria Donatella Semeraro, Cassandra Smith, Melanie Kaiser, Itamar Levinger, Gustavo Duque, Hans Jürgen Gruber, Markus Herrmann · 2020 · Aging
- DNA damage processing at telomeres: The ends justify the meansElise Fouquerel, Dhvani Parikh, Patricia Lynn Opresko · 2016 · DNA repair
- Secrets from immortal worms: What can we learn about biological ageing from the planarian model system?Sounak Sahu, Anish Dattani, Aziz A. Aboobaker · 2017 · Seminars in Cell and Developmental Biology
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- Observation of processive telomerase catalysis using high-resolution optical tweezersEric M. Patrick, Joseph D. Slivka, Bramyn Payne, Matthew Comstock, Jens C. Schmidt · 2020 · Nature Chemical Biology
- Telomere Dysfunction in Idiopathic Pulmonary FibrosisKexiong Zhang, Lu Xu, Yu‐Sheng Cong · 2021 · Frontiers in Medicine
- A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissuesBenjamin Werner, David Dingli, Arne Traulsen · 2013 · Journal of The Royal Society Interface
- Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell DifferentiationGui‐An Huang, Linlin Liu, Huasong Wang, Mo Gou, Peng Gong, Chenglei Tian, Wei Deng, Jiao Yang, Tian-Tian Zhou, Guo-Liang Xu et al. · 2020 · iScience
- The hallmarks of aging in Ataxia-TelangiectasiaJulio Aguado, Cecilia Gómez‐Inclán, Hannah C. Leeson, Martin Francis Lavin, Yosef Shiloh, Ernst Jurgen Wolvetang · 2022 · Ageing Research Reviews
- Interstitial Lung Disease: NHLBI Workshop on the Primary Prevention of Chronic Lung DiseasesIván O. Rosas, Paul F. Dellaripa, David J. Lederer, Dinesh Khanna, Lisa R. Young, Fernando J. Martínez · 2014 · Annals of the American Thoracic Society
- Sex differences in leucocyte telomere length in a free‐living mammalRebecca L. Watson, Ellen J. Bird, Sarah Underwood, Rachael V. Wilbourn, Jennifer Fairlie, Kathryn Watt, Eliane Salvo‐Chirnside, Jill G. Pilkington, Josephine M. Pemberton, Tom Nathan McNeilly et al. · 2016 · Molecular Ecology
- Telomerase RNA processing: Implications for human health and diseaseNeha Nagpal, Suneet Agarwal · 2020 · Stem Cells
- BRD4 inhibitors block telomere elongationWang, Steven, Pike, Alexandra M., Lee, Stella S., Strong, Margaret A., Connelly, Carla J., Greider, Carol W. · 2017 · Nucleic Acids Research
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- Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven mannerMeng Wang, Laura T. L. Brandt, Xiaonan Wang, Holly Russell, Emily Mitchell, Ashley N. Kamimae-Lanning, Jill M. Brown, Felix A. Dingler, Juan I. Garaycoechea, Tomoya Isobe et al. · 2023 · Molecular Cell
- Associations of healthy eating patterns with biological aging: national health and nutrition examination survey (NHANES) 1999–2018Xuanyang Wang, Xuemin Yan, Jiafan Zhang, Sijia Pan, Ran Li, Licheng Cheng, Xiang Qi, Lin Li, Ying Li · 2024 · Nutrition Journal
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- A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of TelomeraseAnagha Killedar, Michael D. Stutz, Alexander P. Sobinoff, Christopher G. Tomlinson, Tracy M. Bryan, Jonathan Beesley, Georgia Chenevix‐Trench, Roger R. Reddel, Hilda A. Pickett · 2015 · PLoS Genetics
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- Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosisJoseph M. Kelich, Tomas M. Aramburu, Joanne J. van der Vis, Louise C. Showe, Andrew V. Kossenkov, Jasper J. van der Smagt, Maarten P.G. Massink, Angela E. Schoemaker, Eric A. M. Hennekam, Marcel Veltkamp et al. · 2022 · The Journal of Experimental Medicine
- Pathogenesis of idiopathic pulmonary fibrosis: review of recent findingsElisabetta Augusta Renzoni, Srihari Veeraraghavan, Piersante Sestini · 2014 · F1000Prime Reports
- Fission Yeast Shelterin Regulates DNA Polymerases and Rad3ATR Kinase to Limit Telomere ExtensionYa-Ting Chang, Bettina A. Moser, Toru Nakamura · 2013 · PLoS Genetics