The telomere syndromes

Armanios, Mary, Blackburn, Elizabeth H.·2012·Nature Reviews Genetics

Cited by (975)

Items 301–400 of 975

  1. The turquoise killifish: a genetically tractable model for the study of aging
    Michael Poeschla, Dario Riccardo Valenzano · 2020 · Journal of Experimental Biology
  2. Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita
    Siddharth Shukla, Ho‐Chang Jeong, Christopher M. Sturgeon, Roy Parker, Luís F.Z. Batista · 2020 · Blood Advances
  3. Alternative splicing is a developmental switch for hTERT expression
    Alex Penev, Andrew Bazley, Michael J. Shen, Jef D. Boeke, Sharon A. Savage, Agnel J. Sfeir · 2021 · Molecular Cell
  4. Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects
    Laëtitia Kermasson, Dmitri Churikov, Aya Awad, Riham Smoom, Élodie Lainey, Fabien Touzot, Séverine Audebert‐Bellanger, Sophie Haro, Lauréline Roger, Emília Costa et al. · 2022 · Blood
  5. Regulated assembly and disassembly of the yeast telomerase quaternary complex
    Timothy M. Tucey, Victoria Lundblad · 2014 · Genes & Development
  6. The wide-ranging clinical implications of the Short Telomere Syndromes
    Barbaro, P. M., Ziegler, D. S., Reddel, R. R. · 2016 · Internal Medicine Journal
  7. Telomeres as hotspots for innate immunity and inflammation
    Joe Nassour, Sara Przetocka, Jan Karlseder · 2023 · DNA repair
  8. Homocysteine-related hTERT DNA demethylation contributes to shortened leukocyte telomere length in atherosclerosis
    Donghong Zhang, Xuemei Wen, Wei Wu, Ermu Xu, Yujuan Zhang, Wei Cui · 2013 · Atherosclerosis
  9. Telomere-Regulating Genes and the Telomere Interactome in Familial Cancers
    Carla Daniela Robles‐Espinoza, Martin Del Castillo Velasco‐Herrera, Nicholas K. Hayward, David J. Adams · 2014 · Molecular Cancer Research
  10. Structure of Est3 reveals a bimodal surface with differential roles in telomere replication
    Timsi Rao, Johnathan W. Lubin, Geoffrey S. Armstrong, Timothy M. Tucey, Victoria Lundblad, Deborah S. Wuttke · 2013 · Proceedings of the National Academy of Sciences
  11. Telomerase activity in pregnancy complications (Review)
    Persefoni Fragkiadaki, Dimitris Tsoukalas, Irene Fragkiadoulaki, Christos Psycharakis, Dragana Nikitovic, Demetrios A. Spandidos, Aristidis Michael Tsatsakis · 2016 · Molecular Medicine Reports
  12. p53 Mediates Failure of Human Definitive Hematopoiesis in Dyskeratosis Congenita
    Wilson C. Fok, Evandro Luís de Oliveira Niero, Carissa Dege, Kirsten Ann Brenner, Christopher M. Sturgeon, Luís F.Z. Batista · 2017 · Stem Cell Reports
  13. Gene therapy with the TRF 1 telomere gene rescues decreased TRF 1 levels with aging and prolongs mouse health span
    Aksinya Derevyanko, Kurt Whittemore, Ralph P. Schneider, Verónica Jiménez, Fátima Bosch, Marı́a A. Blasco · 2017 · Aging Cell
  14. Expression of the human telomerase reverse transcriptase gene is modulated by quadruplex formation in its first exon due to DNA methylation
    Pei‐Tzu Li, Zifu Wang, I-Te Chu, Yen-Min Kuan, Minghao Li, Mu-Ching Huang, Pei-Chi Chiang, Ta‐Chau Chang, Chin‐Tin Chen · 2017 · Journal of Biological Chemistry
  15. Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita
    Wilson C. Fok, Siddharth Shukla, Alexandre Teixeira Vessoni, Kirsten Ann Brenner, Roy Parker, Christopher M. Sturgeon, Luís F.Z. Batista · 2019 · Blood
  16. Spectrum of hematological malignancies, clonal evolution and outcomes in 144 Mayo Clinic patients with germline predisposition syndromes
    Emma C. St. Martin, Alejandro Ferrer, Abhishek Avinash Mangaonkar, Shakila P. Khan, Mira A. Kohorst, Avni Y. Joshi, William J. Hogan, Horatiu Olteanu, Ann M. Moyer, Aref Al‐Kali et al. · 2021 · American Journal of Hematology
  17. AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer
    Muñoz-Lorente, Miguel A., Martínez, Paula, Tejera, Águeda, Whittemore, Kurt, Moisés-Silva, Ana Carolina, Bosch, Fàtima, Blasco, Maria A. · 2018 · PLOS Genetics
  18. Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length
    Daniele Campa, Alessandro Martino, Judit Várkonyi, Fabienne Lesueur, Krzysztof Jamroziak, Stefano Landi, Artur J. Jurczyszyn, Herlander Marques, Vibeke Charlotte Andersen, Manuel Jurado et al. · 2014 · International Journal of Cancer
  19. Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes
    R. Alex Wu, Yavuz S. Dagdas, S. T. Yılmaz, Ahmet Yıldız, Kathleen Collins · 2015 · eLife
  20. Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis
    Rosa María Marión, Isabel López de Silanes, Lluc Mosteiro, Benjamin J. Gamache, María Abad, Carmen E. Guerra, Diego Megı́as, Manuel Serrano, Marı́a A. Blasco · 2017 · Stem Cell Reports
  21. TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly
    Basma M. Klump, Gloria I. Perez, Eric M. Patrick, Kate Adams-Boone, Scott B. Cohen, Han Li, Kefei Yu, Jens C. Schmidt · 2023 · Cell Reports
  22. A homozygous telomerase T-motif variant resulting in markedly reduced repeat addition processivity in siblings with Hoyeraal Hreidarsson syndrome
    Maria Monica Gramatges, Xiaodong Qi, Ghadir Sasa, Julian J.‐L. Chen, Alison A. Bertuch · 2013 · Blood
  23. Maternal Estriol Concentrations in Early Gestation Predict Infant Telomere Length
    Sonja Entringer, Elissa S. Epel, Jue Lin, Elizabeth Helen Blackburn, Claudia Buß, Hyagriv N. Simhan, Pathik D. Wadhwa · 2014 · The Journal of Clinical Endocrinology & Metabolism
  24. Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts
    Dhvani Parikh, Elise Fouquerel, Connor T. Murphy, Hong Wang, Patricia Lynn Opresko · 2015 · Nature Communications
  25. A Truncating Germline Mutation of TINF2 in Individuals with Thyroid Cancer or Melanoma Results in Longer Telomeres
    Huiling He, Wei Li, Daniel F. Comiskey, Sandya Liyanarachchi, Taina Tuulikki Nieminen, Yanqiang Wang, Katherine E. DeLap, Pamela L. Brock, Albert de la Chapelle · 2020 · Thyroid
  26. Hematopoiesis under telomere attrition at the single-cell resolution
    Natthakan Thongon, Feiyang Ma, Andrea Santoni, Matteo Marchesini, Elena Fiorini, Ashley M. Rose, Vera Ademà, Irene Gañán‐Gómez, Emma M. Groarke, Fernanda Gutierrez‐Rodrigues et al. · 2021 · Nature Communications
  27. Predicting Survival from Telomere Length versus Conventional Predictors: A Multinational Population-Based Cohort Study
    Dana A. Glei, Noreen Goldman, Rosa Ana Risques, David H. Rehkopf, William H. Dow, Luis Rosero‐Bixby, Maxine Weinstein · 2016 · PLoS ONE
  28. Mitotic Dysfunction Associated with Aging Hallmarks
    Joana Catarina Macedo, Sara Vaz, Elsa Logarinho · 2017 · Advances in experimental medicine and biology
  29. Insights from human genetic studies of lung and organ fibrosis
    Christine Kim Garcia · 2018 · Journal of Clinical Investigation
  30. Longitudinal associations of lifetime adiposity with leukocyte telomere length and mitochondrial DNA copy number
    Dong Hang, Hongmei Nan, Ane Sørlie Kværner, Immaculata De Vivo, Andrew Tan Chan, Zhibin Hu, Hongbing Shen, Edward L. Giovannucci, Mingyang Song · 2018 · European Journal of Epidemiology
  31. Hereditary Predisposition to Hematopoietic Neoplasms
    Abhishek Avinash Mangaonkar, Mrinal M. Patnaik · 2020 · Mayo Clinic Proceedings
  32. Lifespan and telomere length variation across populations of wild‐derived African killifish
    Martin Reichard, Kety Giannetti, Tânia Ferreira, Ahmed Maouche, Milan Vrtílek, Matěj Polačik, Radim Blažek, Miguel Godinho Ferreira · 2021 · Molecular Ecology
  33. Loss of Telomere Protection: Consequences and Opportunities
    Jacqueline J.L. Jacobs · 2013 · Frontiers in Oncology
  34. Telomeres in lung disease
    John M. Gansner, Iván O. Rosas · 2013 · Translational research
  35. Cell populations can use aneuploidy to survive telomerase insufficiency
    Caroline Millet, Darya Ausiannikava, Thierry Le Bihan, Sander Granneman, Svetlana Makovets · 2015 · Nature Communications
  36. Impact of Gln94Glu mutation on the structure and function of protection of telomere 1, a cause of cutaneous familial melanoma
    Mohd. Amir, Shahnawaz Ahmad, Shahzaib Ahamad, Vijay Kumar, Taj Mohammad, Ravins Dohare, Mohamed Fahad Alajmi, Md Tabish Rehman, Afzal Hussain, Asimul Islam et al. · 2019 · Journal of Biomolecular Structure and Dynamics
  37. High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders
    Kevin Norris, Amanda J. Walne, Mark Ponsford, Kez Cleal, Julia W. Grimstead, Alicia Ellison, Jenna Alnajar, Inderjeet S Dokal, Tom Vulliamy, Duncan M. Baird · 2021 · Human Genetics
  38. Translating Measures of Biological Aging to Test Effectiveness of Geroprotective Interventions: What Can We Learn from Research on Telomeres?
    Waylon James Hastings, Idan Shalev, Daniel W. Belsky · 2017 · Frontiers in Genetics
  39. Targeting the hallmarks of aging: mechanisms and therapeutic opportunities
    Fumihiro Sanada, Shinichiro Hayashi, Ryuichi Morishita · 2025 · Frontiers in Cardiovascular Medicine
  40. Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2
    Parminder Kaur, Dong Wu, Jiangguo Lin, Preston J. Countryman, Kira Bradford, Dorothy A. Erie, Robert E. Riehn, Patricia Lynn Opresko, Hong Wang · 2016 · Scientific Reports
  41. Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions
    Dechao Cao, Juan Zhao, Lam N. Nguyan, Lam Nhat Nguyen, Sushant Khanal, Xindi Dang, Madison Schank, Bal Krishna Chand Thakuri, Xiao Y. Wu, Zheng D. Morrison et al. · 2019 · Frontiers in Immunology
  42. Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese
    Yuya Shirai, Suguru Honda, Katsunori Ikari, Masahiro Kanai, Yoshito Takeda, Yoichiro Kamatani, Takayuki Morisaki, Eiichi Tanaka, Atsushi Kumanogoh, Masayoshi Harigai et al. · 2020 · Annals of the Rheumatic Diseases
  43. Bone Marrow Failure Syndromes, Overlapping Diseases with a Common Cytokine Signature
    Valentina Giudice, Chiara Cardamone, Massimo Triggiani, Carmine Selleri · 2021 · International Journal of Molecular Sciences
  44. Telomerase Activity and Telomere Length in Daphnia
    Charles Andrew Schumpert, Jacob Nelson, Eunsuk Kim, Jeffry L. Dudycha, Rekha C. Patel · 2015 · PLoS ONE
  45. Emerging roles of i-motif in gene expression and disease treatment
    Xiaoqing Luo, Jianye Zhang, Yue Gao, Weifei Pan, Yayuan Yang, Xu Li, Lingfei Chen, Chang Wang, Yuqing Wang · 2023 · Frontiers in Pharmacology
  46. Biological aging in multiple sclerosis
    Yinan Zhang, Jeffrey Atkinson, Christin Elizabeth Burd, Jennifer S. Graves, Benjamin M. Segal · 2023 · Multiple Sclerosis Journal
  47. Chromosomal Processes in Mind-Body Medicine: Chronic Stress, Cell Aging, and Telomere Length
    Tobias Esch, Richard M. Kream, George B. Stefano · 2018 · Medical science monitor basic research/Medical science monitor. Basic research
  48. Marital disruption is associated with shorter salivary telomere length in a probability sample of older adults
    Mark A. Whisman, Briana L. Robustelli, David A. Sbarra · 2016 · Social Science & Medicine
  49. Inhibition of TRF2 accelerates telomere attrition and DNA damage in naïve CD4 T cells during HCV infection
    Lam Nhat Nguyen, Juan Zhao, Dechao Cao, Xindi Dang, Ling Wang, Jianqi Lian, Ying Zhang, Zhansheng Jia, Xiao Y. Wu, Zheng D. Morrison et al. · 2018 · Cell Death and Disease
  50. Idiopathic pulmonary fibrosis and the role of genetics in the era of precision medicine
    Aitana Alonso-González, Eva Tosco-Herrera, María Molina‐Molina, Carlos Flores · 2023 · Frontiers in Medicine
  51. Understanding telomere diseases through analysis of patient-derived iPS cells
    Luís F.Z. Batista, Steven E. Artandi · 2013 · Current Opinion in Genetics & Development
  52. Cytomegalovirus is associated with reduced telomerase activity in the Whitehall II cohort
    Jennifer B. Dowd, Jos A. Bosch, Andrew Steptoe, Elizabeth Helen Blackburn, Jue Lin, Erin Rees-Clayton, Allison E. Aiello · 2013 · Experimental Gerontology
  53. Incorporating genetics into the identification and treatment of Idiopathic Pulmonary Fibrosis
    Susan K. Mathai, Ivana V. Yang, Marvin I. Schwarz, David A. Schwartz · 2015 · BMC Medicine
  54. Structural biology of telomerase and its interaction at telomeres
    Yaqiang Wang, Juli F. Feigon · 2017 · Current Opinion in Structural Biology
  55. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association
    Yilin Wang, Kathryn S. Brady, Benjamin P. Caiello, Stephanie M. Ackerson, Jason A. Stewart · 2019 · Life Science Alliance
  56. Cellular response to chronic psychosocial stress: Ten-year longitudinal changes in telomere length in the Multi-Ethnic Study of Atherosclerosis
    Helen C.S. Meier, Mustafa Hussein, Belinda L. Needham, Sharrelle Barber, Jue Lin, Teresa E. Seeman, Ana Victoria Diez Roux · 2019 · Psychoneuroendocrinology
  57. Cancer and myeloid clonal evolution in the short telomere syndromes
    Kristen E. Schratz, Mary Y. Armanios · 2020 · Current Opinion in Genetics & Development
  58. Integrated Genome-wide association and hypothalamus eQTL studies indicate a link between the circadian rhythm-related gene PER1 and coping behavior
    Siriluck Ponsuksili, Manuela Zebunke, Eduard Muráni, Nares Trakooljul, J. Krieter, Birger Puppe, M. Schwerin, Klaus Wimmers · 2015 · Scientific Reports
  59. Genetic cartography of longevity in humans and mice: Current landscape and horizons
    Michael Hook, Suheeta Roy, Evan G. Williams, Maroun S. Bou Sleiman, Khyobeni Mozhui, James F. Nelson, Lu Lu, Johan H. Auwerx, Robert W. Williams · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  60. Cardiac telomere length in heart development, function, and disease
    Scott A. Booth, Fadi Joseph Charchar · 2017 · Physiological Genomics
  61. Leukocyte telomere length variation in different stages of schizophrenia
    Pawan Kumar Maurya, Lucas Bortolotto Rizzo, Gabriela Xavier, Priscila Farias Tempaku, Vanessa Ota, Marcos Leite Santoro, Letícia Spíndola, Patrícia Natália Silva Moretti, Diego R. Mazzotti, Ary Gadelha et al. · 2017 · Journal of Psychiatric Research
  62. Fanconi anemia and dyskeratosis congenita/telomere biology disorders: Two inherited bone marrow failure syndromes with genomic instability
    Moisés Ó. Fiesco-Roa, Benilde García‐de Teresa, Paula Leal-Anaya, Renée Van‘t Hek, Talía Wegman-Ostrosky, Sara Frı́as, Alfredo Rodríguez · 2022 · Frontiers in Oncology
  63. Molecular and Genetic Biomarkers in Idiopathic Pulmonary Fibrosis: Where Are We Now?
    Ioannis P. Tomos, Ioannis Roussis, Andreas Μ. Matthaiou, Katerina Dimakou · 2023 · Biomedicines
  64. Telomerase Reverse Transcriptase Polymorphism rs2736100: A Balancing Act between Cancer and Non-Cancer Disease, a Meta-Analysis
    Reinier Snetselaar, Matthijs F.M. van Oosterhout, Jan C. Grutters, Coline H.M. van Moorsel · 2018 · Frontiers in Medicine
  65. Clinical Correlates and Treatment Outcomes for Patients With Short Telomere Syndromes
    Abhishek Avinash Mangaonkar, Alejandro Ferrer, Filippo Pinto e Vairo, Margot A. Cousin, Ryan J. Kuisle, Eric W. Klee, Cassie C. Kennedy, Steve G. Peters, J.P. Scott, James P. Utz et al. · 2018 · Mayo Clinic Proceedings
  66. Telomeres and telomerase in risk assessment of cardiovascular diseases
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  67. Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis
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  68. Tpz1-Ccq1 and Tpz1-Poz1 Interactions within Fission Yeast Shelterin Modulate Ccq1 Thr93 Phosphorylation and Telomerase Recruitment
    Jennifer L. Harland, Ya-Ting Chang, Bettina A. Moser, Toru Nakamura · 2014 · PLoS Genetics
  69. The association between obstructive sleep apnea and shortened telomere length: a systematic review and meta-analysis
    Pan Huang, Jianghua Zhou, Shanping Chen, Chuan Zou, Xiufang Zhao, Jiping Li · 2017 · Sleep Medicine
  70. Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV
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  71. Telomeres in toxicology: Occupational health
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  72. To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End Protection
    Stephanie M. Ackerson, Carlan V. Romney, P. Logan Schuck, Jason A. Stewart · 2021 · Frontiers in Cell and Developmental Biology
  73. Akt regulates TPP 1 homodimerization and telomere protection
    Xin Han, Dan Liu, Yi Zhang, Yujing Li, Weisi Lu, Junjie Chen, Zhou Songyang · 2013 · Aging Cell
  74. No evidence for parental age effects on offspring leukocyte telomere length in free-living Soay sheep
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  75. Role of angiotensin II in aging
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  76. The differential spatiotemporal expression pattern of shelterin genes throughout lifespan
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  77. First heterozygousNOP10mutation in familial pulmonary fibrosis
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  78. Phospholipase A2 receptor 1 promotes lung cell senescence and emphysema in obstructive lung disease
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  79. A Test of Biological and Behavioral Explanations for Gender Differences in Telomere Length: The Multi-Ethnic Study of Atherosclerosis
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  80. Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase
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  81. The interaction effects of polycyclic aromatic hydrocarbons exposure and TERT- CLPTM1L variants on longitudinal telomere length shortening: A prospective cohort study
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  82. Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias
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  83. Pulmonary fibrosis linked to variants in theACDgene, encoding the telomere protein TPP1
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  84. PML is required for telomere stability in non-neoplastic human cells
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  85. Comparison of different methods for telomere length measurement in whole blood and blood cell subsets: Recommendations for telomere length measurement in hematological diseases
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  86. Telomere length and hTERT in mania and subsequent remission
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  87. Early pregnancy intrauterine fetal exposure to maternal smoking and impact on fetal telomere length
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  88. Short and dysfunctional telomeres sensitize the kidneys to develop fibrosis
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  89. A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches
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  90. Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance
    Géraldine Servant, Prescott L. Deininger · 2016 · Frontiers in Genetics
  91. Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes
    Amanda C. Hall, Lauren Ostrowski, Violena Pietrobon, Karim Mekhail · 2017 · Nucleus
  92. Single-cell transcriptomics identifies premature aging features of TERC-deficient mouse brain and bone marrow
    Chunying Yang, Yidan Pang, Yigang Huang, Fang Ye, Xiaoyi Chen, Youshui Gao, Changqing Zhang, Lufeng Yao, Junjie Gao · 2022 · GeroScience
  93. Telomere biology: from disorders to hematological diseases
    Kleoniki Roka, Elena E. Solomou, Antonis Kattamis · 2023 · Frontiers in Oncology
  94. In situ visualization of telomere elongation patterns in human cells
    Morgan E. Diolaiti, Beth A. Cimini, Robin Kageyama, Florie A. Charles, Bradley A. Stohr · 2013 · Nucleic Acids Research
  95. Multiple genetic pathways regulate replicative senescence in telomerase‐deficient yeast
    Bari J. Ballew, Victoria Lundblad · 2013 · Aging Cell
  96. Tetrahymena Telomerase Holoenzyme Assembly, Activation, and Inhibition by Domains of the p50 Central Hub
    Kyungah Hong, Heather E. Upton, Edward J. Miracco, Jiansen Jiang, Z. Hong Zhou, Juli F. Feigon, Kathleen Collins · 2013 · Molecular and Cellular Biology
  97. Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human
    Yaqiang Wang, Joseph David Yesselman, Qi Zhang, Mijeong Kang, Juli F. Feigon · 2016 · Proceedings of the National Academy of Sciences
  98. Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance.Part 1: Diagnosis
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  99. Dynamics of human telomerase recruitment depend on template-telomere base pairing
    Jens C. Schmidt, Arthur J. Zaug, Regina Kufer, Thomas R. Cech · 2018 · Molecular Biology of the Cell
  100. Telomeres, species differences, and unusual telomeres in vertebrates: presenting challenges and opportunities to understanding telomere dynamics
    Emory D. Ingles, Janine E. Deakin · 2016 · Global Medical Genetics