The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Transgenerational epigenetic inheritance: how important is it?
Open accessAbstract
Much attention has been given to the idea of transgenerational epigenetic inheritance, but fundamental questions remain regarding how much takes place and the impact that this might have on organisms. We asked five leading researchers in this area — working on a range of model organisms and in human disease — for their views on these topics. Their responses highlight the mixture of excitement and caution that surrounds transgenerational epigenetic inheritance and the wide gulf between species in terms of our knowledge of the mechanisms that may be involved.
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Cites
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
Law, J. A., & Jacobsen, S. E. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2719 · Cited by 3,850
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
Brangwynne, C. P., Eckmann, C. R., Courson, D. S., Rybarska, A., Hoege, C., Gharakhani, J., Jülicher, F., & Hyman, A. A. (2009) · Science · doi:10.1126/science.1172046 · Cited by 3,202
Genomic imprinting: parental influence on the genome
Reik, W., & Walter, J. (2001) · Nature Reviews Genetics · doi:10.1038/35047554 · Cited by 2,285
Kato, M., Han, T. W., Xie, S., Shi, K., Du, X., Wu, L. C., Mirzaei, H., Goldsmith, E. J., Longgood, J., Pei, J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.017 · Cited by 2,012
ALSPAC–The Avon Longitudinal Study of Parents and Children
Golding, Pembrey, Jones, & The Alspac Study Team (2001) · Paediatric and Perinatal Epidemiology · doi:10.1046/j.1365-3016.2001.00325.x · Cited by 1,549
Epigenetic inheritance at the agouti locus in the mouse
Morgan, H. D., Sutherland, H. G. E., Martin, D. I. K., & Whitelaw, E. (1999) · Nature Genetics · doi:10.1038/15490 · Cited by 1,476
Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring
Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., & Morris, M. J. (2010) · Nature · doi:10.1038/nature09491 · Cited by 1,327
Manning, K., Tör, M., Poole, M., Hong, Y., Thompson, A. J., King, G. J., Giovannoni, J. J., & Seymour, G. B. (2006) · Nature Genetics · doi:10.1038/ng1841 · Cited by 1,310
Hou, F., Sun, L., Zheng, H., Skaug, B., Jiang, Q.-X., & Chen, Z. J. (2011) · Cell · doi:10.1016/j.cell.2011.06.041 · Cited by 1,282
An epigenetic mutation responsible for natural variation in floral symmetry
Cubas, P., Vincent, C., & Coen, E. (1999) · Nature · doi:10.1038/43657 · Cited by 1,238
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Hanson, M. A., & Gluckman, P. D. (2014) · Physiological Reviews · doi:10.1152/physrev.00029.2013 · Cited by 1,188
Deans, C., & Maggert, K. A. (2015) · Genetics · doi:10.1534/genetics.114.173492 · Cited by 554
Social Structure, Adversity, Toxic Stress, and Intergenerational Poverty: An Early Childhood Model
McEwen, C. A., & McEwen, B. S. (2017) · Annual Review of Sociology · doi:10.1146/annurev-soc-060116-053252 · Cited by 472
Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions
Klengel, T., & Binder, E. B. (2015) · Neuron · doi:10.1016/j.neuron.2015.05.036 · Cited by 353
Nongenetic inheritance and transgenerational epigenetics
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Metadata
- Authors
- Grossniklaus, U., Kelly, W. G., Ferguson-Smith, A. C., Pembrey, M., & Lindquist, S.
- Venue
- Nature Reviews Genetics
- Published
- 2013-02-18
- Volume
- 14
- Issue
- 3
- Pages
- 228-235
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W1976935056
- Cited by
- 301
- References
- 88
- FWCI
- 3.07
- Type
- journal article
- Language
- en
- Open access
- green
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- Grossniklaus, U., Kelly, W. G., Ferguson-Smith, A. C., Pembrey, M., & Lindquist, S. (2013). Transgenerational epigenetic inheritance: how important is it? Nature Reviews Genetics. https://doi.org/10.1038/nrg3435
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
