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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Roles of Fc receptors in autoimmunity

Open access
Takai, Toshiyuki·2002·Nature Reviews Immunology

Abstract

The receptors for the Fc of immunoglobulins, Fc receptors (FcRs), link the humoral and cellular branches of the immune system, and they have important functions in the activation and down-modulation of immune responses. Balanced signalling through activating and inhibitory FcRs regulates the activity of various cells in the immune system. Recent work in animal models indicates that the development of many human autoimmune diseases might be caused by impairment of the FcR regulatory system. This review provides an overview of the mechanisms of FcR-based immune regulation and describes how autoimmune disease might result from its dysfunction.

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Metadata

Authors
Takai, T.
Venue
Nature Reviews Immunology
Published
2002-08-01
Volume
2
Issue
8
Pages
580-592
ISSN
  • 1474-1733 (ISSN-L)
  • 1474-1741
OpenAlex
W1530035084
Cited by
626
References
3
FWCI
3.42
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Roles of Fc receptors in autoimmunity. https://app.cochat.ai/papers/10.1038/nri856
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Takai, T. (2002). Roles of Fc receptors in autoimmunity. Nature Reviews Immunology. https://doi.org/10.1038/nri856

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.