The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Roles of Fc receptors in autoimmunity
Open accessAbstract
The receptors for the Fc of immunoglobulins, Fc receptors (FcRs), link the humoral and cellular branches of the immune system, and they have important functions in the activation and down-modulation of immune responses. Balanced signalling through activating and inhibitory FcRs regulates the activity of various cells in the immune system. Recent work in animal models indicates that the development of many human autoimmune diseases might be caused by impairment of the FcR regulatory system. This review provides an overview of the mechanisms of FcR-based immune regulation and describes how autoimmune disease might result from its dysfunction.
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Ghazizadeh, S., Bolen, J. B., & Fleit, H. B. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37050-3 · Cited by 202
Hashimoto, A., Okada, H., Jiang, A., Kurosaki, M., Greenberg, S., Clark, E. A., & Kurosaki, T. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.7.1287 · Cited by 199
Christianson, G. J., Brooks, W., Vekasi, S., Manolfi, E. A., Niles, J., Roopenian, S. L., Roths, J. B., Rothlein, R., & Roopenian, D. C. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.10.4781 · Cited by 98
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Metadata
- Authors
- Takai, T.
- Venue
- Nature Reviews Immunology
- Published
- 2002-08-01
- Volume
- 2
- Issue
- 8
- Pages
- 580-592
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W1530035084
- Cited by
- 626
- References
- 3
- FWCI
- 3.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
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