Nuclear DNA damage signalling to mitochondria in ageing

Fang, Evandro Fei, Scheibye-Knudsen, Morten, Chua, Katrin F., Mattson, Mark P., Croteau, Deborah L., Bohr, Vilhelm A.·2016·Nature Reviews Molecular Cell Biology

DOI 10.1038/nrm.2016.14

Cited by (398)

Items 201–300 of 398

Mitochondrial Genome Maintenance: Damage and Repair Pathways
Ulises Omar García‐Lepe, Rosa María Bermúdez‐Cruz · 2019 · IntechOpen eBooks
Modulation of copper-induced antioxidant defense, Cu transport, and mitophagy by hypoxia in the large yellow croaker (Larimichthys crocea)
Yun Pan, C. Ai, Lin Zeng, Can Liu, Wen-Cheng Li · 2020 · Fish Physiology & Biochemistry
Cardiac Cell Senescence and Redox Signaling
Daniela Cesselli, Aneta Aleksova, Sandro Sponga, Celeste Cervellin, Carla Di Loreto, Gianluca Tell, Antonio Paolo Beltrami · 2017 · Frontiers in Cardiovascular Medicine
Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes
Tatsuya Hasegawa, Saori Noguchi, Masaya Nakashima, Masashi Miyai, Makiko Goto, Yuko Mizuno Matsumoto, Satoru Torii, Shinya Honda, Shigeomi Shimizu · 2024 · Journal of Biological Chemistry
Mitophagy pathways and Alzheimer's disease: From pathogenesis to treatment
Xian-Ji Pan, Afzal Misrani, Sidra Tabassum, Li Yang · 2021 · Mitochondrion
PM2.5-Induced Programmed Myocardial Cell Death via mPTP Opening Results in Deteriorated Cardiac Function in HFpEF Mice
Tingting Wu, Minghui Tong, Aiai Chu, Kaiyue Wu, Xiaowei Niu, Zheng Zhang · 2022 · Cardiovascular Toxicology
Mechanism and treatment of intracerebral hemorrhage focus on mitochondrial permeability transition pore
Jing Cong, Jing Li, Wei Zou · 2024 · Frontiers in Molecular Neuroscience
Acute exercise boosts NAD+ metabolism of human peripheral blood mononuclear cells
David Walzik, Niklas Joisten, Alexander Schenk, Sina Trebing, Kirill Schaaf, Alan J. Metcalfe, Polyxeni Spiliopoulou, Johanna Hiefner, Adrian McCann, Carsten Watzl et al. · 2024 · Brain Behavior and Immunity
Overexpression of RAD51B predicts a preferable prognosis for non-small cell lung cancer patients
Mengyin Wu, Zu-Feng Sheng, Lingyan Jiang, Zhengyuan Liu, Yuhua Bi, Yueping Shen · 2017 · Oncotarget
H2A.Z is involved in premature aging and DSB repair initiation in muscle fibers
Edwige Belotti, Nicolas Lacoste, Arslan Iftikhar, Thomas Simonet, Christophe Papin, Alexis Osseni, Nathalie Streichenberger, Pierre‐Olivier Mari, Emmanuelle Girard, Mohamed Graies et al. · 2024 · Nucleic Acids Research
From Powerhouse to Perpetrator—Mitochondria in Health and Disease
Nima Borhan Fakouri, Thomas Lau Hansen, Claus Desler, Sharath Anugula, Lene Juel Rasmussen · 2019 · Biology
Photostable NIR emitting ruthenium(II) conjugates; uptake and biological activity in live cells
David Cullinane, Karmel Sofia Gkika, Aisling Byrne, Tia E. Keyes · 2020 · Journal of Inorganic Biochemistry
Sirtuins: not only animal proteins
Izabela Szućko-Kociuba · 2016 · Acta Physiologiae Plantarum
Approaches to Mitigate Mitochondrial Dysfunction in Sensorineural Hearing Loss
Mustafa Nazir Okur, Hamid Reza Djalilian · 2022 · Annals of Biomedical Engineering
Mitochondrial microRNAs: New Emerging Players in Vascular Senescence and Atherosclerotic Cardiovascular Disease
Paola Canale, Andrea Borghini · 2024 · International Journal of Molecular Sciences
Mitochondria: fundamental characteristics, challenges, and impact on aging
Runyu Liang, Luwen Zhu, Yongyin Huang, Jia Chen, Qiang Tang · 2024 · Biogerontology
Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Ralf Paus, Yuval Ramot, Robert Scott Kirsner, Marjana Tomic‐Canic · 2020 · Experimental Dermatology
Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
Megan R. Reed, Leena Maddukuri, Amit D. Ketkar, Stephanie D. Byrum, Maroof Khan Zafar, April C.L. Bostian, Alan J. Tackett, Robert Lawton Eoff · 2021 · NAR Cancer
Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model
Gustavo Satoru Kajitani, Lear E. Brace, Jose Humberto Trevino-Villarreal, Kaspar M. Trocha, Michael Robert MacArthur, Sarah C. Vose, Dorathy Vargas, Roderick Terry Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck et al. · 2021 · Aging
Age-related Mitochondrial Dysfunction in Parkinson's Disease: New Insights Into the Disease Pathology
Linchi Rani, Manas Ranjan Sahu, Amal Chandra Mondal · 2022 · Neuroscience
Presequence protease reverses mitochondria‐specific amyloid‐β‐induced mitophagy to protect mitochondria
Yunxiao Dou, Yan Tan · 2023 · The FASEB Journal
The Role for the DSB Response Pathway in Regulating Chromosome Translocations
Rajib Ghosh, Debamitra Das, Sonia Franco · 2018 · Advances in experimental medicine and biology
Homocysteine interferes with Ndufa1 leading to mitochondrial dysfunction through repression of the NAD+/Sirt1 pathway in the brain: a possible link between hyperhomocysteinemia and neurodegeneration
Gaoshang Chai, Yuming Mao, Juan Gong, Shuguang Bi, Yuqi Zhang, Jiajun Wu, Yang Liu, Tianlong Gao, Haitian Fu, Chunjing Yu et al. · 2025 · Cell Death and Disease
Treatment of age-related visual impairment with a peptide acting on mitochondria
N.M. Alam, R.M. Douglas, Glen T. Prusky · 2021 · Disease Models & Mechanisms
Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase
Dullovi, Arlinda, Ozgencil, Meryem, Rajvee, Vinothini, Tse, Wai Yiu, Cutillas, Pedro R., Martin, Sarah A., Hořejší, Zuzana · 2023 · iScience
Impact of cardiovascular involvement on the clinical course of paediatric mitochondrial disorders
Alice Brambilla, Iacopo Olivotto, Silvia Favilli, Gaia Spaziani, Silvia Passantino, Elena Procopio, Amelia Morrone, Maria Alice Donati · 2020 · Orphanet Journal of Rare Diseases
Delineating the Role of Mitophagy Inducers for Alzheimer Disease Patients
Wenwen Wang, Ruiyu Han, Haijun He, Zhen Wang, Xiaoqian Luan, Jia Li, Liang Feng, Siyan Chen, Yahyah Aman, Chenglong Xie · 2021 · Aging and Disease
Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome
Ruben Gudmundsrud, Tarjei H. Skjånes, Brian C. Gilmour, Domenica Caponio, Sofie Lautrup, Evandro Fei Fang · 2021 · Cytogenetic and Genome Research
Period3 modulates the NAD+-SIRT3 axis to alleviate depression-like behaviour by enhancing NAMPT activity in mice
Xiaoxian Xie, Haoshen Xu, Ruonan Shu, Shulin Du, Haidan Fan, Mengya Zhang, Lei Sun, Jiafeng Zhou, Liangliang Wang, Zezhi Li et al. · 2025 · Journal of Advanced Research
A Molecular Perspective and Role of NAD+ in Ovarian Aging
Mehboob Ahmed, Umair Riaz, Haimiao Lv, Liguo Yang · 2024 · International Journal of Molecular Sciences
Complex Interplay between DNA Damage and Autophagy in Disease and Therapy
Aman Deep Singh, Naresh Ravendranathan, Jefferson C. Frisbee, Krishna Kumar Singh · 2024 · Biomolecules
Septic Shock and the Aging Process: A Molecular Comparison
Fabiano Pinheiro da Silva, Marcel Cerqueira César Machado · 2017 · Frontiers in Immunology
Panobinostat and venetoclax enhance the cytotoxicity of gemcitabine, busulfan, and melphalan in multiple myeloma cells
Benigno C. Valdez, Yang Li, David L. Murray, Yan Liu, Yago L. Nieto, Qaiser Bashir, Muzaffar H. Qazilbash, Börje S. Andersson · 2020 · Experimental Hematology
Chromatin Modifier EP400 Regulates Oocyte Quality and Zygotic Genome Activation in Mice
Qing Tian, Ying Yin, Yu Tian, Yufan Wang, Y Wang, Rikiro Fukunaga, Toshihiro Fujii, Aihua Liao, Lei Li, Wei Zhang et al. · 2024 · Advanced Science
Stimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome
Deena Damschroder, Ruben Zapata Perez, Kristin Richardson, Frédéric Maxime Vaz, Riekelt H. Houtkooper, Robert J. Wessells · 2022 · Disease Models & Mechanisms
Pharmacological intervention of early neuropathy in neurodegenerative diseases
Min Jee Kwon, Jeong‐Hoon Kim, Tae Soo Kim, Sung Bae Lee · 2017 · Pharmacological Research
Constitutive MAP-kinase activation suppresses germline apoptosis in NTH-1 DNA glycosylase deficient C. elegans
Henok Kassahun, Tanima SenGupta, Alfonso Schiavi, Silvia Maglioni, Hanne K. Skjeldam, Katarzyna D. Arczewska, Nicole L. Brockway, Suzanne Estes, Lars Eide, Natascia Ventura et al. · 2017 · DNA repair
Knockdown of SIRT1 inhibits proliferation and promotes apoptosis of paclitaxel-resistant human cervical cancer cells
Xiaoyan Xia, Xiaoming Zhou · 2018 · Cellular and Molecular Biology
DNA damage responses in central nervous system and age-associated neurodegeneration
Muralidhar L. Hegde, Vilhelm A. Bohr, SANKAR P. MITRA · 2017 · Mechanisms of Ageing and Development
Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
Tanima SenGupta, Yohan Lefol, Lisa Lirussi, Verónica Suaste, Torben Lüders, Swapnil Gupta, Yahyah Aman, Kulbhushan Sharma, Evandro Fei Fang, Hilde Loge Nilsen · 2022 · Aging
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders
Tessa J. Helman, Nady Braidy · 2022 · Drugs & Aging
Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway
Rich Milton R. Dulay, Benigno C. Valdez, Yang Li, Seemanti Chakrabarti, Braham Deep Singh Dhillon, Sofronio P. Kalaw, Renato G. Reyes, Esperanza C. Cabrera · 2021 · PLoS ONE
Cell Reprogramming Preserving Epigenetic Age: Advantages and Limitations
E. Samoylova, V. Baklaushev · 2020 · Biochemistry (Moscow)
Neuroprotective effect of mildronate and L-carnitine on the cognitive parameters of aged mice and mice with LPS-induced inflammation
Ekaterina A. Shaforostova, Artem P. Gureev, Daria E. Volodina, Vasily N. Popov · 2022 · Metabolic Brain Disease
Estrés oxidativo mitocondrial y envejecimiento cardíaco
Beatriz Martín‐Fernández, Ricardo Gredilla · 2018 · Clínica e Investigación en Arteriosclerosis
Can neurodevelopmental disorders influence the course of neurodegenerative diseases? A scoping review
Perrine Laury Marie Siguier, Mélanie Planton, Éloïse Baudou, Yves Chaix, A Delage, Marie Rafiq, Marie Wolfrum, Fleur Gérard, Mélanie Jucla, Jérémie Pariente · 2024 · Ageing Research Reviews
Licochalcone D exhibits cytotoxicity in breast cancer cells and enhances tumor necrosis factor‐related apoptosis‐inducing ligand‐induced apoptosis through upregulation of death receptor 5
Yunyun Zhang, Linlin Wang, Chuxuan Dong, Yahui Zhuang, Gangping Hao, Feng-Ze Wang · 2024 · Journal of Biochemical and Molecular Toxicology
Harnessing gut microbiota for longevity: Insights into mechanisms and genetic manipulation
Peng Shi, Simin Xu, Ziling Yang, Liying Wang, Yalun Wu, Ying Li, Zuobin Zhu · 2024 · iMetaOmics.
Comparative study of ginsenoside Rg2, 20(S)-protopanaxatriol, and AFG from ginseng on aging-related kidney injury in SAMP8 mice
Ivan Stève Nguepi Tsopmejio, Jingtian Zhang, Zi Wang, Zhao-feng Tian, Hongyan Zhu, Jing Zhang, Shen Ren, Shuang Liu, Hui Liu, Junnan Hu et al. · 2025 · Journal of Ethnopharmacology
The Multi-Dimensional Action Map of Resveratrol Against Alzheimer’s Disease: Mechanism Integration and Treatment Strategy Optimization
Yichen Liu, Yadan Dong, Zhen Cao, Yixuan Ji, Xiaoxin Cheng, Xu Zheng · 2025 · Nutrients
LARP7 overexpression alleviates aortic senescence and atherosclerosis
Ping Yang, Shuo Wu, Yige Li, Yingmei Lou, Junhao Xiong, Yuze Wang, Zilong Geng, Bing Zhang · 2024 · Journal of Cellular and Molecular Medicine
Mitochondrial oxidative stress and cardiac ageing
Beatriz Martín‐Fernández, Ricardo Gredilla · 2018 · Clínica e Investigación en Arteriosclerosis (English Edition)
Lifelong docosahexaenoic acid intervention ameliorates aging in the telomere-DNA-mitochondria axis in telomerase-deficient mice
Shanyun Wu, Yuqi Wu, Jingnan Chen, Pan Zhuang, Yu Zhang, Jingjing Jiao · 2022 · The Journal of Nutritional Biochemistry
Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins
Teruaki Iyama, Mustafa Nazir Okur, Tyler Golato, Daniel R. McNeill, Huiming Lu, Royce J. Hamilton, Aishwarya Raja, Vilhelm A. Bohr, David M. Wilson · 2018 · Scientific Reports
The whole transcriptome regulation as a function of mitochondrial polymorphisms and aging in Caenorhabditis elegans
Yuanjian Song, Yuechen Wang, Ying Li, Liang Wang, WenDa Zhang, Jing Cheng, Yao Zhu, Haoyu Zhang, Qiang Zhang, Haichen Niu et al. · 2020 · Aging
Cochlear metabolomics, highlighting novel insights of purine metabolic alterations in age-related hearing loss
Huanzhi Wan, Wenjing Wang, Jingchun Liu, Yunlong Zhang, Bingqian Yang, Rongkai Hua, Huidong Chen, Shiming Chen, Qingquan Hua · 2023 · Hearing Research
Associations of Frailty with Neuropsychiatric Symptoms of Alzheimer’s Disease: A Longitudinal Study
Hao‐Chen Chi, Lingzhi Ma, Zhibo Wang, Ze-Hu Sheng, Jia-Yao Liu, Yin‐Chu Mi, Yin‐Chu Mi, Yi‐Ming Huang, Shuang-Ling Han, Pei‐Yang Gao et al. · 2024 · Journal of Alzheimer s Disease
Supplementation with NAD+ Precursors for Treating Alzheimer’s Disease: A Metabolic Approach
Mohammed Abdualrhman Alghamdi, Nady Braidy · 2024 · Journal of Alzheimer s Disease
A blood-based DNA damage signature in patients with Parkinson’s disease is associated with disease progression
Daisy Sproviero, César Payán‐Gómez, Chiara Milanese, Sander Barnhoorn, Shixiang Sun, Ákos Gyenis, Domenico Delia, Tammaryn Lashley, Jan H.J. Hoeijmakers, Jan Vijg et al. · 2025 · Nature Aging
Mitochondrial Factors in the Cell Nucleus
Katiuska González‐Arzola, Antonio Dı́az-Quintana · 2023 · International Journal of Molecular Sciences
Acupoint catgut embedding improves senescence in a rat model of ageing by regulating mitophagy via the PINK1 pathway
Meiling Zhou, Yumei Yuan, Zishu Lin, Bin Zhang, Wenluo Qin, Yongqiang Liu, Cong Yang, Qi Wang, Hong Zhang · 2021 · Journal of Cellular and Molecular Medicine
Mitochondrial dysfunction in mandibular hypoplasia, deafness and progeroid features with concomitant lipodystrophy (MDPL) patients
Michela Murdocca, Paola Spitalieri, Angela Cappello, Fiorella Colasuonno, Sandra Moreno, Eleonora Candi, Maria Rosaria D’Apice, Giuseppe Novelli, Federica Carla Sangiuolo · 2022 · Aging
Genetics of aging and longevity
Alexey Moskalev, Ekaterina Proshkina, A. A. Belyi, Ilya A. Solovev · 2017 · Russian Journal of Genetics Applied Research
The Role of DNA Repair in Maintaining Mitochondrial DNA Stability
Linlin Zhang, Aurelio Reyes, Xiangdong Wang · 2017 · Advances in experimental medicine and biology
Cancer Imprints an Increased PARP-1 and p53-Dependent Resistance to Oxidative Stress on Lymphocytes of Patients That Later Develop Alzheimer's Disease
Felipe Salech, Daniela P. Ponce, Carol D. SanMartín, Nicole K. Rogers, Mauricio Henríquez, María Isabel Behrens · 2018 · Frontiers in Neuroscience
Vitamin D Supplementation Reverses DNA Damage and Telomeres Shortening Caused by Ovariectomy in Hippocampus of Wistar Rats
Cassiana Siebert, Tiago Marcon dos Santos, Carolina Gessinger Bertó, Mariana Migliorini Parisi, Ritiéle Pinto Coelho, Vanusa Manfredini, Florencia María Barbé‐Tuana, Ângela Terezinha de Souza Wyse · 2018 · Neurotoxicity Research
Mitochondria-targeting near-infrared (NIR) materials orchestrating the symphony of precision diagnosis and therapy
Shu Gao, Chunrong Qu, Jun Wang, Kun Qian, Zhen Cheng · 2024 · Nano Today
DNA damage in proximal tubules triggers systemic metabolic dysfunction through epigenetically altered macrophages
Erina Sugita Nishimura, Akihito Hishikawa, Ran Nakamichi, Riki Akashio, Shunsuke Chikuma, Akinori Hashiguchi, Norifumi Yoshimoto, Eriko Yoshida Hama, Tomomi Maruki, Wataru Ito et al. · 2025 · Nature Communications
Broken strands, broken minds: Exploring the nexus of DNA damage and neurodegeneration
Ioanna Stavgiannoudaki, Evi Goulielmaki, George A. Garinis · 2024 · DNA repair
The past-tense debate
Steven A. Pinker, Michael T. Ullman · 2002
Dysregulated autophagy-related genes in septic cardiomyopathy: Comprehensive bioinformatics analysis based on the human transcriptomes and experimental validation
Hua-Xi Zou, Bai‐Quan Qiu, Zeyu Zhang, Tie Hu, Li Wan, Jichun Liu, Huang Huang, Songqing Lai · 2022 · Frontiers in Cardiovascular Medicine
From cue to meaning: The involvement of POLD1 gene in DNA replication, repair and aging
Michela Murdocca, Paola Spitalieri, Maria Rosaria D’Apice, Giuseppe Novelli, Federica Carla Sangiuolo · 2023 · Mechanisms of Ageing and Development
Disrupting lipid homeostasis with CAV2 in OSCC triggers apoptosis, lipolysis, and mitochondrial dysfunction by transcriptional repression of PPARγ
Yuting Bai, Mingjing Jiang, Xiaojie Chen, Gang Zhou · 2025 · Cell & Bioscience
Advances in the Understanding of Mitochondrial Inflammatory Regulation in the Pathogenesis of Alzheimer’s Disease
Ren-Zhen Zhang, Li Li, Cui Ma, Tingting Dou, Yu-Ting Wei, Xingke Yan · 2025 · Journal of Inflammation Research
Energy metabolism rewiring following acute UVB irradiation is largely dependent on nuclear DNA damage
L. Dousset, Walid Mahfouf, Hadi Younes, Hala Fatrouni, Corinne Faucheux, Elodie Muzotte, Ferial Khalife, Rodrigue Rossignol, François Moisan, Muriel Cario et al. · 2024 · Free Radical Biology and Medicine
Therapeutic modulation of mitochondrial dynamics by agmatine in neurodegenerative disorders
Dhanshree Nibrad, Amit Shiwal, Manasi Tadas, Raj Katariya, Mayur Bhimrao Kale, Nandkishor Ramdas Kotagale, Milind Janrao Umekar, Brijesh Gulabrao Taksande · 2025 · Neuroscience
BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans
Alessandro Torgovnick, Alfonso Schiavi, Anjumara Shaik, Henok Kassahun, Silvia Maglioni, Shane L. Rea, Thomas E. Johnson, Hans Christian Reinhardt, Sebastian Honnen, Björn Schumacher et al. · 2018 · EMBO Reports
“Mitochondrial Toolbox” – A Review of Online Resources to Explore Mitochondrial Genomics
Ruaidhri Cappa, Cassio Polpo de Campos, Alexander Peter Maxwell, Amy Jayne McKnight · 2020 · Frontiers in Genetics
Regulation of the mitochondrial permeability transition pore and its effects on aging
Damiano Pellegrino-Coppola · 2020 · Microbial Cell
Nicotinamide effects on the metabolism of human fibroblasts and keratinocytes assessed by quantitative, label-free fluorescence imaging
Zhiyi Liu, C.‐Y. Chiang, John Nip, Lin Feng, Yang Zhang, Sheila Rocha, Irene Georgakoudi · 2021 · Biomedical Optics Express
Location, location, location: subcellular protein partitioning in proteostasis and aging
Anita V. Kumar, Louis R. Lapierre · 2021 · Biophysical Reviews
Molecular mechanisms of immune cell death in immunosenescence
Joost Verduijn, Kelly Coutant, Mitchell E. Fane, Lorenzo Galluzzi · 2025 · Cell Death and Differentiation
Mitochondrial DNA polymorphisms in COX1 affect the lifespan of Caenorhabditis elegans through nuclear gene dct-15
Yao Zhu, Ying Li, Yuechen Wang, Liang Wang, Peng Shi, Xinze Du, Yingchun Zhang, Yuanjian Song, Zuobin Zhu · 2022 · Gene
Role of mitochondria in nuclear DNA damage response
Xipeng Zhao, Bin Chen, Lijun Wu, Guoping Zhao · 2022 · Genome Instability & Disease
Sirtuins, NAD + , Aging, and Disease
Leonard Guarente · 2018 · Elsevier eBooks
Mitochondrial behavior during nuclear and mitochondrial DNA repair in Trypanosoma cruzi epimastigotes
Tamires Marco Antônio Salgado Martins, Eduardo de Figueiredo Peloso, Héllida Marina Costa-Silva, Matheus Andrade Rajão, Bennet Van Houten, Carlos Renato Machado, Fernanda Ramos Gadelha · 2020 · Experimental Parasitology
Platinum anticancer drugs: Targeting and delivery
Zhiqin Deng, Houzong Yao, Zhigang Wang, Guangyu Zhu · 2022 · Elsevier eBooks
Rapid profiling of DNA replication dynamics using mass spectrometry–based analysis of nascent DNA
Mohamed E. Ashour, Andrea K. Byrum, Alice Meroni, Jun Xia, Saurabh S. Singh, Roberto Galletto, Susan M. Rosenberg, Alessandro Vindigni, Nima Mosammaparast · 2023 · The Journal of Cell Biology
Enterohemorrhagic Escherichia coli effector EspF triggers oxidative DNA lesions in intestinal epithelial cells
Yuting Fang, Muqing Fu, Xinyue Li, Bao Zhang, Chengsong Wan · 2024 · Infection and Immunity
Detecting Apoptosis as a Clinical Endpoint for Proof of a Clinical Principle
Piero Zollet, Timothy E. Yap, Maria Francesca Cordeiro · 2020 · Ophthalmologica
Lifespan and Healthspan Extension by Nutraceuticals: An Overview
Sergio Davinelli, Giovanni Scapagnini · 2019 · Springer eBooks
The impact of exercise on telomere length dynamics: Molecular mechanisms and implications in athletes (Review)
Stella Baliou, Marios Spanakis, Miruna-Maria Apetroaei, Πέτρος Ιωάννου, Persefoni Fragkiadaki, Irene Fragkiadoulaki, Elisavet A. Renieri, Elena Vakonaki, Manolis N. Tzatzarakis, Alexander E. Nosyrev et al. · 2025 · World Academy of Sciences Journal
Telomerase mRNA therapy protects human skin against radiation-induced DNA damage
Shuang Li, David F. Chang, Karem A. Court, Thi Kim Cuc Nguyen, Vrutant V. Shah, Elisa Morales, Jack Carrier, Anjana Tiwari, Andrew T. Ludlow, Kristopher W. Brannan et al. · 2025 · Molecular Therapy
Promising Results With NAD Supplementation in Rare Diseases With Premature Aging and DNA Damage
Vilhelm A. Bohr · 2025 · Aging Cell
A short-lived fish with long-lasting effects: hallmarks of aging in Nothobranchius furzeri
Oksana Savel, Julien Lehmann, Yusuf Kaan Poyraz, Melissa M. Page · 2026 · Frontiers in Aging
Genetic and Epigenetic Sexual Dimorphism of Brain Cells during Aging
Olesya M. Shirokova, Olga Zaborskaya, Pavel V. Pchelin, Elizaveta V. Kozliaeva, Vladimir I. Pershin, Irina Vasilievna Mukhina · 2023 · Brain Sciences
Alzheimer's Disease: From Animal Models to the Human Syndrome
Erika Orta‐Salazar, Isaac Vargas-Rodríguez, Susana A. Castro-Chavira, Alfredo Feria‐Velasco, Sofía Y. Díaz-Cintra · 2016 · InTech eBooks
Editorial: Cellular Senescence and Cellular Communications Within Tissue Microenvironments During Aging
Ziyu Wei, Heng Ma, Evandro Fei Fang, Hou‐Zao Chen · 2022 · Frontiers in Physiology
Premature aging in serious mental illness.
B. Diniz, Gabriel R Fries, Chia-Ling Kuo, Ming Xu, E. Lenze · 2026 · Neuropsychopharmacology
STUB1-VCP/p97 complex regulates mitophagy via fine-tuning of PINK1 levels
Jin-Yi Lin, Ze-Bo Huang, Shi-Qi Zhang, Yong Wu, Ling-Jun Cheng, Xiangzheng Gao, Sofie Lautrup, Shuqin Cao, Junping Pan, Dade Rong et al. · 2026 · Cell Reports