Biochemical and cellular properties of insulin receptor signalling

Haeusler, Rebecca A., McGraw, Timothy E., Accili, Domenico·2018·Nature Reviews Molecular Cell Biology

Cites (254)

Items 201–252 of 252

  1. SH2B Regulation of Growth, Metabolism, and Longevity in Both Insects and Mammals
    Wei Song, Decheng Ren, Wenjun Li, Lin Jiang, Kae Won Cho, Ping Huang, Chen Fan, Yiyun Song, Yong Liu, Liangyou Rui · 2010 · Cell Metabolism
  2. SH2B1 regulation of energy balance, body weight, and glucose metabolism
    Liangyou Rui · 2014 · World Journal of Diabetes
  3. PHLPP-Mediated Dephosphorylation of S6K1 Inhibits Protein Translation and Cell Growth
    Jianyu Liu, Payton D. Stevens, Xin Li, Micheal D. Schmidt, Tianyan Gao · 2011 · Molecular and Cellular Biology
  4. SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins
    David Lee Morris, Kae Won Cho, Yingjiang Zhou, Liangyou Rui · 2009 · Diabetes
  5. The vascular endothelial cell mediates insulin transport into skeletal muscle
    Hong Wang, Zhenqi Liu, Guolian Li, Eugene J. Barrett · 2006 · American Journal of Physiology-Endocrinology and Metabolism
  6. Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway
    Yoshiaki Hirashima, Kaku Tsuruzoe, S Kodama, Motoyuki Igata, T Toyonaga, Kohjiro Ueki, C.Ronald Kahn, Eiichi Araki · 2003 · Journal of Endocrinology
  7. Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia
    Stella P. Kim, Karyn J. Catalano, Isabel R. Hsu, Jenny D. Chiu, Joyce M. Richey, Richard N. Bergman · 2007 · American Journal of Physiology-Endocrinology and Metabolism
  8. Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2
    A Suwa, Tadashi S. Yamamoto, A Sawada, Kyubei Minoura, Naomi Hosogai, Atsuo Tahara, Takeshi Kurama, T. Shimokawa, Ichiro Aramori · 2009 · British Journal of Pharmacology
  9. Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity
    Jerry Thwin Wong, P. T. W. Kim, James W. Peacock, Tien Yin Yau, Alice Mui, Stephen W. Chung, Vesna Sossi, Doris J. Doudet, D. Green, T.J. Ruth et al. · 2006 · Diabetologia
  10. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling
    Arunachalam Vinayagam, Meghana M. Kulkarni, Richelle Sopko, Xiaoyun Sun, Yanhui Hu, Ankita Nand, Christians Villalta, Ahmadali M. Moghimi, Xuemei Yang, Stephanie Elizabeth Mohr et al. · 2016 · Cell Reports
  11. Regulation of insulin and type 1 insulin‐like growth factor signaling and action by the G rb10/14 and SH 2 B 1/ B 2 adaptor proteins
    Bernard Desbuquois, Nadège Carré, Anne‐Françoise Burnol · 2012 · FEBS Journal
  12. Chapter 3 Molecular Mechanisms of Differential Intracellular Signaling From the Insulin Receptor
    Maja Jensen, Pierre DE MEYTS · 2009 · Vitamins and hormones
  13. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis
    Sona Kang, Linus T.-Y. Tsai, Yiming Zhou, Adam G. Evertts, Su Xu, Michael J. Griffin, Robbyn Issner, Holly J. Whitton, Benjamin Aaron Garcia, Charles B. Epstein et al. · 2014 · Nature Cell Biology
  14. mTOR-Dependent Regulation of PHLPP Expression Controls the Rapamycin Sensitivity in Cancer Cells
    Jianyu Liu, Payton D. Stevens, Tianyan Gao · 2010 · Journal of Biological Chemistry
  15. Protein tyrosine phosphatase 1B: a new target for the treatment of obesity and associated co‐morbidities
    Olavi H. Ukkola, Merja Santaniemi · 2002 · Journal of Internal Medicine
  16. Type 2 Diabetes Risk Alleles Near BCAR1 and in ANK1 Associate With Decreased β-Cell Function Whereas Risk Alleles Near ANKRD55 and GRB14 Associate With Decreased Insulin Sensitivity in the Danish Inter99 Cohort
    Marie Neergaard Harder, Rasmus Ribel‐Madsen, Johanne Marie Justesen, Thomas Sparsø, Ehm Astrid Andersson Galijatovic, Niels Grarup, Torben Jørgensen, Allan R Linneberg, Torben F. Hansen, Oluf Borbye Pedersen · 2013 · The Journal of Clinical Endocrinology & Metabolism
  17. Dissociation of the Glucose and Lipid Regulatory Functions of FoxO1 by Targeted Knockin of Acetylation-Defective Alleles in Mice
    Alexander S. Banks, Ja Young Kim-Muller, Teresa L. Mastracci, Natalie M. Kofler, Li Qiang, Rebecca A. Haeusler, Michael J. Jurczak, Dina Laznik, Garrett Heinrich, Varman T. Samuel et al. · 2011 · Cell Metabolism
  18. SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes
    Joanne Bruno, Alexandria Brumfield, Natasha Chaudhary, David B. Iaea, Timothy E. McGraw · 2016 · The Journal of Cell Biology
  19. Dual Ablation of Grb10 and Grb14 in Mice Reveals Their Combined Role in Regulation of Insulin Signaling and Glucose Homeostasis
    Lowenna J. Holt, Ruth J. Lyons, Ashleigh S. Ryan, Susan M. Beale, Andrew Ward, Gregory James Cooney, Roger J. Daly · 2009 · Molecular Endocrinology
  20. Structural Basis for Dimerization of the Grb10 Src Homology 2 Domain
    Evan Gary Stein, Rodolfo Ghirlando, Stevan R. Hubbard · 2003 · Journal of Biological Chemistry
  21. Impact of the Liver-Specific Expression of SHIP2 (SH2-Containing Inositol 5′-Phosphatase 2) on Insulin Signaling and Glucose Metabolism in Mice
    Kazuhito Fukui, Tsutomu Wada, Syota Kagawa, Kiyofumi Nagira, Mariko Ikubo, Hajime Ishihara, Masashi Kobayashi, Toshiyasu Sasaoka · 2005 · Diabetes
  22. Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice
    Samuel T. Nadler, Jonathan P. Stoehr, Mary E. Rabaglia, Kathryn L. Schueler, Morris J. Birnbaum, Alan Attie · 2001 · American Journal of Physiology-Endocrinology and Metabolism
  23. SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity
    Vanessa Schmidt, Nadja Schulz, Xin Yan, Annette Schürmann, Stefan Kempa, Matthias Kern, Matthias Blüher, Matthew N. Poy, Gunilla Olivecrona, Thomas E. Willnow · 2016 · Journal of Clinical Investigation
  24. Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance
    Reema P. Vazirani, Akanksha Verma, L. Amanda Sadacca, Melanie S. Buckman, Belén Picatoste, Muheeb Beg, Christopher Torsitano, Joanne Bruno, Rajesh T. Patel, Kotryna Šimonytė et al. · 2016 · Diabetes
  25. Trafficking Kinetics of the Insulin-Regulated Membrane Aminopeptidase in 3T3-L1 Adipocytes
    Stuart A. Ross, John J. Herbst, Susanna R. Keller, Gustav E. Lienhard · 1997 · Biochemical and Biophysical Research Communications
  26. Ceramides – Lipotoxic Inducers of Metabolic Disorders
    Bhagirath Chaurasia, Scott A. Summers · 2017 · Trends in Endocrinology and Metabolism
  27. The adipokine/ceramide axis: Key aspects of insulin sensitization
    Jonathan Y. Xia, Thomas S. Morley, Philipp E. Scherer · 2013 · Biochimie
  28. PP2A inhibition results in hepatic insulin resistance despite Akt2 activation
    Thomas Galbo, Rachel J. Perry, Erica Nishimura, Varman T. Samuel, Bjørn Quistorff, Gerald I. Shulman · 2013 · Aging
  29. The SH2B Gene is Associated with Serum Leptin and Body Fat in Normal Female Twins
    Yalda Jamshidi, Harold Snieder, Dongliang Ge, Tim D. Spector, Sandra D. O’Dell · 2007 · Obesity
  30. Increased Atherosclerosis and Endothelial Dysfunction in Mice Bearing Constitutively Deacetylated Alleles of Foxo1 Gene
    Li Qiang, Kyoichiro Tsuchiya, Ja Young Kim-Muller, Hua V. Lin, Carrie L. Welch, Domenico Accili · 2012 · Journal of Biological Chemistry
  31. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase
    Kyle D. Copps, Nancy J. Hançer, Wei Qiu, Morris F. White · 2016 · Journal of Biological Chemistry
  32. The Effects of Acute and Chronic Starvation on Insulin Binding to Isolated Human Adipocytes*
    Orville Kolterman, Mark Saekow, Jerrold M. Olefsky · 1979 · The Journal of Clinical Endocrinology & Metabolism
  33. ADD-1 provides major new insight into the mechanism of insulin action
    Jeffrey S. Flier, Anthony Neil Hollenberg · 1999 · Proceedings of the National Academy of Sciences
  34. Endothelial Transcytosis of Insulin: Does It Contribute to Insulin Resistance?
    Warren L. Lee, Amira Klip · 2016 · Physiology
  35. Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking
    Maeran Uhm, Merlijn Bazuine, Peng Zhao, Shian-Huey Chiang, Tingting Xiong, Sheelarani Karunanithi, Louise C. Chang, Alan R. Saltiel · 2017 · Science Signaling
  36. Liver Sinusoidal Endothelial Cells Link Hyperinsulinemia to Hepatic Insulin Resistance
    Kyoichiro Tsuchiya, Domenico Accili · 2013 · Diabetes
  37. Normalization of Prandial Blood Glucose and Improvement of Glucose Tolerance by Liver-Specific Inhibition of SH2 Domain–Containing Inositol Phosphatase 2 (SHIP2) in Diabetic KKAy Mice
    Rolf Grempler, Darya Zibrova, Corinna Schoelch, André van Marle, Joerg F. Rippmann, Norbert H. Redemann · 2007 · Diabetes
  38. Development of a new model system to dissect isoform specific Akt signalling in adipocytes
    Esi Kajno, Timothy E. McGraw, Eva Gonzalez · 2015 · Biochemical Journal
  39. Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity
    Xian, Li, Hou, Siyuan, Huang, Zan, Tang, An, Shi, Peiliang, Wang, Qinghua, Song, Anying, Jiang, Shujun, Lin, Zhaoyu, Guo, Shiying et al. · 2015 · Aging
  40. Transgenic and Knockout Models of PP2A
    Jürgen Götz, Andreas Schild · 2003 · Methods in enzymology on CD-ROM/Methods in enzymology
  41. Mitochondria-Associated Endoplasmic Reticulum Membranes in Insulin Signaling
    Guy A. Rutter, Paolo Pinton · 2014 · Diabetes
  42. Erratum: Corrigendum: The lipid phosphatase SHIP2 controls insulin sensitivity
    Shawna M. Clement, U. Krause, Florence Desmedt, Jean‐François Tanti, Jens Behrends, Xavier Pesesse, Tanenori Sasaki, Josef Martin Penninger, Margaret Doherty, Willy Jean Malaisse et al. · 2004 · Nature
  43. Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography
    Kikuko Hotta, Aya Kitamoto, Takuya Kitamoto, Seiho Mizusawa, Hajime Teranishi, Rina So, Tomoaki Matsuo, Yoshio Nakata, Hideyuki Hyogo, Hidenori Ochi et al. · 2012 · Journal of Human Genetics
  44. SOCS-1 deficiency does not prevent diet-induced insulin resistance
    Brice Emanuelli, Yazmín Macotela, Jérémie Boucher, C. Ronald Kahn · 2008 · Biochemical and Biophysical Research Communications
  45. Insulin-induced Effects on the Subcellular Localization of AKT1, AKT2 and AS160 in Rat Skeletal Muscle
    Xiaohua Zheng, Gregory D. Cartee · 2016 · Scientific Reports
  46. Prevalent role of the insulin receptor isoform A in the regulation of hepatic glycogen metabolism in hepatocytes and in mice
    Sabela Díaz-Castroverde, Selene Baos, María Luque, Marianna Di Scala, Gloria González‐Aseguinolaza, Almudena Gómez‐Hernández, Nuria Beneit, Óscar Escribano, Manuel Benito · 2016 · Diabetologia
  47. Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice
    Sabela Díaz-Castroverde, Almudena Gómez‐Hernández, Silvia Fernández, Gema García-Gómez, Marianna Di Scala, Gloria González‐Aseguinolaza, Elisa Fernández‐Millán, Águeda González‐Rodríguez, Marı́a Garcı́a-Bravo, Pierre Chambon et al. · 2016 · Disease Models & Mechanisms
  48. Antisense oligonucleotides against the lipid phosphatase SHIP2 improve muscle insulin sensitivity in a dietary rat model of the metabolic syndrome
    Roland Buettner, Iris Ottinger, Christiane Gerhardt-Salbert, Christian E. Wrede, Jürgen Schölmerich, Leo Cornelius Bollheimer · 2007 · American Journal of Physiology-Endocrinology and Metabolism
  49. Homozygosity for an Allele Encoding Deacetylated FoxO1 Protects Macrophages From Cholesterol-Induced Inflammation Without Increasing Apoptosis
    Kyoichiro Tsuchiya, Alexander S. Banks, Chien-Ping Liang, Ira A. Tabas, Alan R. Tall, Domenico Accili · 2011 · Arteriosclerosis Thrombosis and Vascular Biology
  50. Dissecting signalling by individual Akt/PKB isoforms, three steps at once
    Cesár Osorio‐Fuentealba, Amira Klip · 2015 · Biochemical Journal
  51. Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study
    Zahra N. Sohani, Sonia Savitri Anand, Sébastien Robiou-du-Pont, Katherine Mary Morrison, Sarah Diana McDonald, Stephanie A. Atkinson, Koon Kang Teo, David Meyre · 2016 · PLoS ONE
  52. The SH2B1 obesity locus and abnormal glucose homeostasis: Lack of evidence for association from a meta-analysis in individuals of European ancestry
    Sabrina Prudente, Massimiliano Copetti, Eleonora Morini, C. Mendonca, Francesco Andreozzi, Manisha Chandalia, Roberto Baratta, Fabio Pellegrini, Luana Mercuri, Diego Bailetti et al. · 2013 · Nutrition Metabolism and Cardiovascular Diseases