The Cbl interactome and its functions

Schmidt, Mirko H.H., Dikic, Ivan·2005·Nature Reviews Molecular Cell Biology

Cited by (394)

Items 201–300 of 394

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  2. Cbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunity
    Denise L. Gay, Hilda E. Ramón, Paula M. Oliver · 2008 · Immunologic Research
  3. SAMP8 mice have altered hippocampal gene expression in long term potentiation, phosphatidylinositol signaling, and endocytosis pathways
    Harvey James Armbrecht, Akbar M. Siddiqui, Michael Green, Susan A. Farr, Vijaya B. Kumar, William A. Banks, Ping Patrick, Gul N. Shah, John Edward Morley · 2013 · Neurobiology of Aging
  4. The E3 ligase c‐Cbl regulates dendritic cell activation
    Shin‐Heng Chiou, Payam Shahi, Ryan T. Wagner, Hongbo Hu, Natalia Lapteva, Mamatha R. Seethammagari, Shao‐Cong Sun, Jonathan M. Levitt, David M. Spencer · 2011 · EMBO Reports
  5. Mutations in myeloproliferative neoplasms – their significance and clinical use
    Fiorella Schischlik, Róbert Královics · 2017 · Expert Review of Hematology
  6. Quantitative Interactomics of Lck-TurboID in Living Human T Cells Unveils T Cell Receptor Stimulation-Induced Proximal Lck Interactors
    Xien Yu Chua, Timothy J. Aballo, William G. ElNemer, M.L. Tran, Arthur R. Salomon · 2020 · Journal of Proteome Research
  7. Current Management of Juvenile Myelomonocytic Leukemia and the Impact of RAS Mutations
    Nao Yoshida, Sayoko Doisaki, Seiji Kojima · 2012 · Pediatric Drugs
  8. Insufficient Deactivation of the Protein Tyrosine Kinase Lck Amplifies T-Cell Responsiveness in Acute Coronary Syndrome
    Sergey Pryshchep, Jörg J. Goronzy, Susmita Parashar, Cornelia M. Weyand · 2009 · Circulation Research
  9. Intersectin 1 Enhances Cbl Ubiquitylation of Epidermal Growth Factor Receptor through Regulation of Sprouty2-Cbl Interaction
    Mustafa Nazir Okur, Jolene Ooi, Chee Wai Fong, Natalia J. Martinez, Carlota A. García-Domínguez, José M. Rojas, Graeme R. Guy, John P. O’Bryan · 2011 · Molecular and Cellular Biology
  10. SH 2B3 ( LNK ) mutations from myeloproliferative neoplasms patients have mild loss of function against wild type JAK 2 and JAK 2 V617F
    Maya Koren‐Michowitz, Sigal Gery, Takayuki Tabayashi, De‐Chen Lin, Rocio Alvarez, Arnon Nagler, Harold Phillip Koeffler · 2013 · British Journal of Haematology
  11. Additional Serine/Threonine Phosphorylation Reduces Binding Affinity but Preserves Interface Topography of Substrate Proteins to the c-Cbl TKB Domain
    Qingxiang Sun, Rebecca A. Jackson, Cherlyn Ng, Graeme R. Guy, Jayaraman Sivaraman · 2010 · PLoS ONE
  12. c-CBL E3 Ubiquitin Ligase Is Overexpressed in Cutaneous T-Cell Lymphoma: Its Inhibition Promotes Activation-Induced Cell Death
    Jianqiang Wu, Katrin Agnes Salva, Gary S. Wood · 2014 · Journal of Investigative Dermatology
  13. Assessment of downstream effectors of BCR/ABL protein tyrosine kinase using combined proteomic approaches
    Chia Fang Lee, Stephen Griffiths, Eva Rodríguez‐Suárez, Andrew Pierce, Richard D. Unwin, Ewa Jaworska, Caroline A. Evans, Simon J. Gaskell, Anthony David Whetton · 2010 · PROTEOMICS
  14. Genomic and Epigenomic Landscape of Juvenile Myelomonocytic Leukemia
    Claudia Fiñana, Noel Gómez-Molina, Sandra Alonso-Moreno, Laura Belver · 2022 · Cancers
  15. Drosophila cbl Is Essential for Control of Cell Death and Cell Differentiation during Eye Development
    Yuan Wang, Christian Werz, Dongbin Xu, Zhihong Chen, Ying Li, Ernst Hafen, Andreas Bergmann · 2008 · PLoS ONE
  16. c-CBL regulates melanoma proliferation, migration, invasion and the FAK-SRC-GRB2 nexus
    Minakshi Nihal, Gary S. Wood · 2016 · Oncotarget
  17. Exploring pathway interactions in insulin resistant mouse liver
    Thomas Kelder, Lars Eijssen, Robert Kleemann, Marjan van Erk, Teake Kooistra, Chris T. Evelo · 2011 · BMC Systems Biology
  18. Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation
    Christina Wehrle, Paul Van Slyke, Daniel Dumont · 2009 · Biochemical Journal
  19. CIN85 Modulates the Down-regulation of FcγRIIa Expression and Function by c-Cbl in a PKC-dependent Manner in Human Neutrophils
    Louis Marois, Myriam Vaillancourt, Guillaume Paré, Valérie Gagné, Maria J. Fernandes, Emmanuelle Rollet, Paul H. Naccache · 2011 · Journal of Biological Chemistry
  20. Bone marrow morphology and disease progression in congenital thrombocytopenia: a detailed clinicopathologic and genetic study of eight cases
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  21. Proteolysis-targeting chimeras: A promising technique in cancer therapy for gaining insights into tumor development
    Moyang Lv, Weichao Hu, Shengwei Zhang, Lijiao He, Changjiang Hu, Shiming Yang · 2022 · Cancer Letters
  22. The Ubiquitin Ligase c-Cbl Down-Regulates FcγRIIa Activation in Human Neutrophils
    Louis Marois, Myriam Vaillancourt, Sébastien Marois, Sophie Proulx, Guillaume Paré, Emmanuelle Rollet, Paul H. Naccache · 2009 · The Journal of Immunology
  23. Receptor Tyrosine Kinase Ubiquitylation Involves the Dynamic Regulation of Cbl-Spry2 by Intersectin 1 and the Shp2 Tyrosine Phosphatase
    Mustafa Nazir Okur, Angela Russo, John P. O’Bryan · 2013 · Molecular and Cellular Biology
  24. Regulation of EGFR and Notch signaling by distinct isoforms of D-cbl during Drosophila development
    Yuan Wang, Zhihong Chen, Andreas Bergmann · 2010 · Developmental Biology
  25. The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness
    Jing Zhang, Olesya Vakhrusheva, Srinivasa Rao Bandi, Özlem Demirel, Julhash Uddin Kazi, Ramona Gomes Fernandes, Katja Jakobi, Astrid Eichler, Lars Rönnstrand, Michael A. Rieger et al. · 2015 · Stem Cell Reports
  26. LAB/NTAL/ Lat2 : a force to be reckoned with in all leukocytes?
    Selinda J. Orr, Daniel W. McVicar · 2010 · Journal of Leukocyte Biology
  27. Redox biology in normal cells and cancer: Restoring function of the redox/Fyn/c-Cbl pathway in cancer cells offers new approaches to cancer treatment
    Mark Noble, Margot Mayer‐Pröschel, Zaibo Li, Tiefei Dong, Wanchang Cui, Christoph Pröschel, Ibro Ambeskovic, Jöerg Dietrich, Ruolan Han, Yin Miranda Yang et al. · 2014 · Free Radical Biology and Medicine
  28. Dual role of Cbl links critical events in BCR endocytosis
    M. Jacob, L. Todd, Matthew Sampson, Ellen Puré · 2008 · International Immunology
  29. Cbl‐b‐dependent degradation of FLIPL is involved in ATO‐induced autophagy in leukemic K562 and gastric cancer cells
    Guodong Zhang, Jing Liu, Ye Zhang, Jinglei Qu, Ling Xu, Hua‐chuan Zheng, Yunpeng Liu, Xiujuan Qu · 2012 · FEBS Letters
  30. The neuropilin-like protein ESDN regulates insulin signaling and sensitivity
    Xuan Li, Jaejoon Jung, Lei Nie, Mahmoud Razavian, Jiasheng Zhang, Varman T. Samuel, Mehran M. Sadeghi · 2016 · American Journal of Physiology-Heart and Circulatory Physiology
  31. Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene
    Scott A. Nadeau, Wei An, Bhopal C. Mohapatra, Insha Mushtaq, Timothy Alan Bielecki, Haitao Luan, Neha Zutshi, Gulzar Ahmad, Matthew D. Storck, Masashi Sanada et al. · 2017 · Journal of Biological Chemistry
  32. Cytoplasmic Retention of a Nucleocytoplasmic Protein TBC1D3 by Microtubule Network Is Required for Enhanced EGFR Signaling
    Ze He, Tian Tian, Dan Guo, Huijuan Wu, Yang Chen, Yongchen Zhang, Qing Wan, Huzi Zhao, Congyang Wang, Hongjing Shen et al. · 2014 · PLoS ONE
  33. Review and Literature Mining on Proteostasis Factors and Cancer
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  34. c‐Cbl regulates glioma invasion through matrix metalloproteinase 2
    Ho‐Jin Lee, Alexander Y. Tsygankov · 2010 · Journal of Cellular Biochemistry
  35. Functional Analyses of Mutations in Receptor Tyrosine Kinase Genes in Non–Small Cell Lung Cancer: Double-Edged Sword of DDR2
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  36. Genetic Basis of MPN: Beyond JAK2-V617F
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  37. Chronic myelomonocytic leukemia: Myelodysplastic or myeloproliferative?
    Raphaël Itzykson, Pierre Fenaux, Éric Solary · 2013 · Best Practice & Research Clinical Haematology
  38. Complex Patterns of Chromosome 11 Aberrations in Myeloid Malignancies Target CBL, MLL, DDB1 and LMO2
    Thorsten Klampfl, Jelena D. Milosevic Feenstra, Ana Puda, Andreas Schönegger, Klaudia Bagienski, Tiina Berg, Ashot S. Harutyunyan, Bettina Gisslinger, Elisa Rumi, Luca Malcovati et al. · 2013 · PLoS ONE
  39. Neuronal Cbl Controls Biosynthesis of Insulin-Like Peptides in Drosophila melanogaster
    Yue Yu, Ying Sun, Shengqi He, Yan Cheng, Liangyou Rui, Wenjun Li, Yong Liu · 2012 · Molecular and Cellular Biology
  40. The emerging roles of E3 ubiquitin ligases in ovarian cancer chemoresistance
    Yang Meng, Lei Qiu, Su Zhang, Junhong Han · 2021 · Cancer Drug Resistance
  41. Pro-Prion is a Membrane Adaptor Protein for E3 Ligase C-Cbl to Ubiquitinate IGF-IR Promoting Melanoma Metastasis
    Huan Li, Jie Zhang, Jing-Ru Ke, Ze Yu, Run Shi, Shanshan Gao, Jingfeng Li, Zhenxing Gao, Changshu Ke, Hui-xia Han et al. · 2022 · Cell Reports
  42. CAP (Cbl associated protein) regulates receptor‐mediated endocytosis
    Daniela Tosoni, Gianluca Cestra · 2008 · FEBS Letters
  43. Vinexin β regulates the phosphorylation of epidermal growth factor receptor on the cell surface
    Masaru Mitsushima, Kazumitsu Ueda, Noriyuki Kioka · 2006 · Genes to Cells
  44. Molecular biology of Philadelphia-negative myeloproliferative neoplasms
    Paulo Vidal Campregher, Fábio Pires de Souza Santos, Guilherme Fleury Perini, Nelson Hamerschlak · 2012 · Revista Brasileira de Hematologia e Hemoterapia
  45. Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm
    Charles Gaulin, Katalin Kelemen, Cecilia Arana Yi · 2022 · Life
  46. c-Cbl regulates αPix-mediated cell migration and invasion
    Min Woo Seong, Ji Ho Park, Hee Min Yoo, Seung Wook Yang, Kyu Hee Oh, Seung Hyeun Ka, Dong Eun Park, Soon‐Tae Lee, Chin Ha Chung · 2014 · Biochemical and Biophysical Research Communications
  47. c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl
    Gayathri Swaminathan, Elena A Feshchenko, Alexander Y. Tsygankov · 2007 · Oncogene
  48. TAGET: a toolkit for analyzing full-length transcripts from long-read sequencing
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  49. A primer on genomic and epigenomic alterations in the myeloproliferative neoplasms
    Raajit K. Rampal, Ross L. Levine · 2014 · Best Practice & Research Clinical Haematology
  50. Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor
    Virginia Sánchez‐Quiles, Vyacheslav Akimov, Nerea Osinalde, Chiara Francavilla, Michele Puglia, Inigo Barrio‐Hernandez, Irina Kratchmarova, Jesper V. Olsen, Blagoy Blagoev · 2017 · Molecular & Cellular Proteomics
  51. c-Cbl mediated ubiquitylation and regulation of cell surface exposure of CD5
    Dmytro Demydenko · 2010 · Biochemical and Biophysical Research Communications
  52. Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia
    Yuka Saito, Yoko Aoki, Hideki Muramatsu, Hideki Makishima, Jaroslaw Pawel Maciejewski, Masue Imaizumi, Takeshi Rikiishi, Yoji Sasahara, Shigeo Kure, Tetsuya Niihori et al. · 2012 · Leukemia Research
  53. c-Cbl deficiency leads to diminished lymphocyte development and functions in an age-dependent manner
    Chozhavendan Rathinam, Richard Anthony Flavell · 2010 · Proceedings of the National Academy of Sciences
  54. Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling
    Claire E. O’Leary, Emma L. Lewis, Paula M. Oliver · 2015 · Frontiers in Immunology
  55. Novel Insights into the Mechanisms of CIN85 SH3 Domains Binding to Cbl Proteins: Solution-Based Investigations and In Vivo Implications
    Abdessamad Ababou, Mark Pfuhl, John Edward Ladbury · 2009 · Journal of Molecular Biology
  56. Ubiquitin and NEDD8: Brothers in Arms
    Mirko H. H. Schmidt, Ivan Đikić · 2006 · Science s STKE
  57. Inhibitory Receptors Signal Activation
    Wayne M. Yokoyama · 2008 · Immunity
  58. Role of the Ror family receptors in Wnt5a signaling
    Koki Kamizaki, Yasuhiro Minami, Michiru Nishita · 2024 · In Vitro Cellular & Developmental Biology - Animal
  59. Deleterious c-Cbl Exon Skipping Contributes to Human Glioma
    Min Woo Seong, Seung Hyeun Ka, Ji Ho Park, Jongho Park, Hee Min Yoo, Seung Wook Yang, Jung Mi Park, Dongeun Park, Soon‐Tae Lee, Jae Hong Seol et al. · 2015 · Neoplasia
  60. Acquired Uniparental Disomy in Myeloproliferative Neoplasms
    J Score, Nicholas C.P. Cross · 2012 · Hematology/Oncology Clinics of North America
  61. Cbl‐family proteins as regulators of cytoskeleton‐dependent phenomena
    Ho‐Jin Lee, Alexander Y. Tsygankov · 2013 · Journal of Cellular Physiology
  62. Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO (RUNX1/RUNX1T1), during myeloid differentiation
    Jesús Duque‐Afonso, Leticia M Solari, Aitomi Essig, Tobias Berg, Heike Luise Pahl, Michael Lübbert · 2011 · British Journal of Haematology
  63. Casitas B-lineage lymphoma mutants activate AKT to induce transformation in cooperation with class III receptor tyrosine kinases
    Harald Polzer, Hanna Janke, Diana Schmid, Wolfgang Hiddemann, Karsten Spiekermann · 2012 · Experimental Hematology
  64. Cool‐1‐Mediated Inhibition of c‐Cbl Modulates Multiple Critical Properties of Glioblastomas, Including the Ability to Generate Tumors In Vivo
    Brett M. Stevens, Christopher J. Folts, Wanchang Cui, Addie L. Bardin, Kevin A. Walter, Eleanor B. Carson-Walter, Angelo Luigi Vescovi, Mark Noble · 2014 · Stem Cells
  65. The protein content of an adaptor protein, STAP-2 is controlled by E3 ubiquitin ligase Cbl
    Yuichi Sekine, Chikako Yamamoto, Osamu Ikeda, Ryuta Muromoto, Asuka Nanbo, Kenji Oritani, Akihiko Yoshimura, Tadashi Matsuda · 2009 · Biochemical and Biophysical Research Communications
  66. D-Cbl Binding to Drk Leads to Dose-Dependent Down-Regulation of EGFR Signaling and Increases Receptor-Ligand Endocytosis
    Pei-Yu Wang, Li‐Mei Pai · 2011 · PLoS ONE
  67. Gain-of-functionc-CBLmutations associated with uniparental disomy of 11q in myeloid neoplasms
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  68. Sp-CBL inhibits white spot syndrome virus replication by enhancing apoptosis in mud crab (Scylla paramamosain)
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  69. Mean-field Boolean network model of a signal transduction network
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  70. Cbl negatively regulates JNK activation and cell death
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  71. Molecular basis and clonal evolution of myeloproliferative neoplasms
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  72. An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding
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  73. The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy
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  74. Circular RNA circSTX12 regulates osteo-adipogenic balance and proliferation of BMSCs in senile osteoporosis
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  76. Indispensable roles of mammalian Cbl family proteins as negative regulators of protein tyrosine kinase signaling
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  77. Immune dysregulation associated with co-occurring germline CBL and SH2B3 variants
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  78. Integration of linear and dendritic actin nucleation in Nck-induced actin comets
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  79. Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia
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  80. C-CBL is required for inhibition of angiogenesis through modulating JAK2/STAT3 activity in ROP development
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  82. SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function
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  83. BLNK negatively regulates innate antifungal immunity through inhibiting c-Cbl-mediated macrophage migration
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  84. Modular Protein Interaction Domains in Cellular Communication
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  90. Cbl proteins in platelet activation
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  95. c-Cbl reduces stability of rescued ∆F508-CFTR in human airway epithelial cells
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  96. Haploinsufficiency of Casitas B-Lineage Lymphoma Augments the Progression of Colon Cancer in the Background of Adenomatous Polyposis Coli Inactivation
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  97. Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth
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  98. Effects on exocytosis by two HSV-1 mutants unable to block autophagy
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  99. CBL-B is required for leukemogenesis mediated by BCR-ABL through negative regulation of bone marrow homing
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