The Cbl interactome and its functions

Schmidt, Mirko H.H., Dikic, Ivan·2005·Nature Reviews Molecular Cell Biology
DOI 10.1038/nrm1762

Cited by (394)

Items 301–394 of 394

  1. Role of c-Cbl Carboxyl Terminus in Serotonin 5-HT2A Receptor Recycling and Resensitization
    Aleksander Baldys, John R. Raymond · 2011 · Journal of Biological Chemistry
  2. Rapid changes in plasma corticosterone and medial amygdala transcriptome profiles during social status change reveal molecular pathways associated with a major life history transition in mouse dominance hierarchies
    Milewski, Tyler M., Lee, Won, Young, Rebecca L., Hofmann, Hans A., Curley, James P. · 2025 · PLoS Genetics
  3. Exploring protein-protein interactions for the development of new analgesics
    Alexandre Martins do Nascimento, Rauni Borges Marques, Allan Pradelli Roldão, Ana Maria G. Dias Rodrigues, Rodrigo Mendes Eslava, Camila Squarzoni Dale, Eduardo M. R. Reis, Deborah Schechtman · 2024 · Science Signaling
  4. Assessing Clinical and Life Sciences Performance of Research Institutions in Split, Croatia, 2000-2006
    Livia Puljak, Katarina Vukojević, Sanja Lovrić Kojundžić, Damir Sapunar · 2008 · Croatian Medical Journal
  5. Adaptor protein complex of FRS 2β and CIN 85/ CD 2 AP provides a novel mechanism for ErbB2/ HER 2 protein downregulation
    Yuriko Minegishi, Yoshio Shibagaki, Anna Mizutani, Koji Fujita, Tohru Tezuka, Masao Kinoshita, Masahiko Kuroda, Seisuke Hattori, Noriko Gotoh · 2012 · Cancer Science
  6. CBL mutations do not frequently occur in paediatric acute myeloid leukaemia
    Eva A. Coenen, Emma M. C. Driessen, Christian Michel Zwaan, Jan Starý, André Baruchel, Válerie de Haas, Eveline S.J.M. de Bont, Dirk Reinhardt, Gertjan J.L. Kaspers, Susan T.C.J.M. Arentsen-Peters et al. · 2012 · British Journal of Haematology
  7. A network analysis revealed the essential and common downstream proteins related to inguinal hernia
    Yimin Mao, Le Chen, Jianghua Li, Anna Junjie Shangguan, Stacy Ann Kujawa, Hong Zhao · 2020 · PLoS ONE
  8. RAS Pathway Mutation Patterns in Patients With Juvenile Myelomonocytic Leukemia: A Developing Country Single-center Experience
    Nayera Hamdy, Hossam Bokhary, Amr El-Sayed, Walaa Hozayn, Sonya Soliman, Sherine Salem, Khaled Alsheshtawi, Amr Abdalla, Hanafy Hafez, Mahmoud Hammad · 2020 · Clinical Lymphoma Myeloma & Leukemia
  9. Differential parsing of EGFR endocytic flux among parallel internalization pathways in lung cancer cells with EGFR-activating mutations
    Alice M. Walsh, Matthew J. Lazzara · 2014 · Integrative Biology
  10. Peritumoral Cbl is a strong independent prognostic marker after curative resection of hepatocellular carcinoma
    Jubo Zhang, Bo Zhang, LeiGuo, Zhen-Hai Lin, Xiaoqiang Li, Kun Guo, Hui‐Chuan Sun, Qing‐Hai Ye · 2015 · Oncotarget
  11. The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes
    Lu Huang, Natalie W. Thiex, Jieqiong Lou, Gulzar Ahmad, Wei An, Shalini T. Low-Nam, Jason G. Kerkvliet, Hamid Band, Adam D. Hoppe · 2024 · Molecular Biology of the Cell
  12. Inhibitory effect of SPE‐39 due to tyrosine phosphorylation and ubiquitination on the function of Vps33B in the EGF‐stimulated cells
    Ayumi Ishii, Kanae Kamimori, Mineyoshi Hiyoshi, Hiroshi Kido, Takeshi Ohta, Hiroaki Konishi · 2012 · FEBS Letters
  13. c-Casitas b-Lineage Lymphoma Downregulation Improves the Ability of Long-term Cultured Mesenchymal Stem Cells for Promoting Angiogenesis and Diabetic Wound Healing
    Chengcheng Shen, Yuangang Lu, Jianghe Zhang, Yujie Li, Yiming Zhang, Dongli Fan · 2021 · Cell Transplantation
  14. Stable and EGF-Induced Temporal Interactome Profiling of CBL and CBLB Highlights Their Signaling Complex Diversity
    Jie Liu, Lijun Yang, An He, Mi Ke, Changying Fu, Weina Gao, Ruilian Xu, Ruijun Tian · 2021 · Journal of Proteome Research
  15. Cbl as a Master Regulator of Receptor Tyrosine Kinase Trafficking
    Ke Ma, Stephen C. Kales, Marion M. Nau, Stanley Lipkowitz · 2013 · Springer eBooks
  16. αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor
    Fanny Kortüm, Frederike Leonie Harms, Natascha Hennighausen, Georg Rosenberger · 2015 · PLoS ONE
  17. Profiling Protein Tyrosine Phosphorylation: A Quantitative 45-Plex Peptide-Based Immunoassay
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  18. Common clonal origin of three distinct hematopoietic neoplasms in a single patient: B-cell lymphoma, T-cell lymphoma, and polycythemia vera
    Dingani Nkosi, Andrew W. Allbee, Paul G. Rothberg, Jonathan W. Friedberg, Andrew G. Evans · 2023 · Molecular Case Studies
  19. Immunological and hematological findings as major features in a patient with a new germline pathogenic CBL variant
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  20. CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting
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  21. Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis
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  22. c-Cbl inhibition: A novel therapeutic approach for attenuating myocardial ischemia and reperfusion injury
    Jichun Wang, Li Li, Hong Jiang · 2015 · International Journal of Cardiology
  23. Cancer and Alterations In the Endocytic Pathway
    Rafael Rosell · 2007 · Future Oncology
  24. Role of Protein Ubiquitination and its Functional Importance
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  25. Identification of crucial ubiquitin-associated genes for predicting the effects of immunotherapy and therapeutic agents in colorectal cancer
    Peng Cao, Qilin Li, Danyi Zou, Lin Wang, Zheng Wang · 2024 · Gene
  26. F-box protein FBXB-65 regulates anterograde transport of the kinesin-3 motor UNC-104 through a PTM near its cargo-binding PH domain
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  27. Specific mixing facilitates the comparative quantification of phosphorylation sites with significant dysregulations
    Jing Liu, Bo Xu, Zheyi Liu, Mingming Dong, Jiawei Mao, Ye Zhou, Jin Chen, Fangjun Wang, Hanfa Zou · 2016 · Analytica Chimica Acta
  28. T-cell activation, alterations in systemic lupus erythematosus: A narrative review
    C. Nicolás Téllez, José J. Siachoque, J. María Alejandra Siachoque, M. Heber Siachoque, M. Heber Siachoque · 2018 · Revista Colombiana de Reumatología (English Edition)
  29. Identify new pseudogene RPL7P1-oriented network as a drug target against infections pre-existing diabetes
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  30. Vaginal microbiota in late pregnancy associates with the outcomes of planned induced labor: a multicenter prospective cohort study
    Shiman Hu, Xiuchao Wang, Hongbin Xu, Jiali Xiong, Ying Gu, Xiaohui Cao, Liping Zhou, Yuru Fan, Shanshan Wang, Xueqi Bai et al. · 2026 · American Journal of Obstetrics and Gynecology
  31. Genetic landscape of stage II melanoma identifies CBL as a new driver gene and prognostic biomarker
    Elena Sophia Lindner, Jakob Admard, German M. Demidov, Sorin Armeanu–Ebinger, Tobias W. Sinnberg, Heike Niessner, Teresa Amaral, Claus Garbe, Andrea Forschner, Olga Kelemen et al. · 2026 · British Journal of Cancer
  32. The Caenorhabditis elegansCDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells
    Gino B Poulin, Julie Ahringer · 2010 · BMC Developmental Biology
  33. Fibroblast growth factor (FGF) and FGF receptor families in bone
    Pierre J. Marie, Marja M. Hurley, David M. Ornitz · 2019 · Elsevier eBooks
  34. c-CBL E3 Ubiquitin Ligase Expression Increases Across the Spectrum of Benign and Malignant T-Cell Skin Diseases
    Katrin Agnes Salva, Margo J. Reeder, Rita Lloyd, Gary S. Wood · 2016 · American Journal of Dermatopathology
  35. Isoflurane decreases interleukin-2 production by increasing c-Cbl and Cbl-b expression in rat peripheral blood mononuclear cells
    Ji Won Choi, Byung Seop Shin · 2018 · Journal of International Medical Research
  36. Update on the Biology of Myeloproliferative Neoplasms
    Róbert Královics · 2011 · Springer eBooks
  37. Retinopathy as an initial sign of hereditary immunological diseases: report of six families and challenges in eye clinic
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  38. Targeting the colony-stimulating factor 1 axis for the treatment of Tenosynovial Giant Cell Tumors
    Paul Humbert, Charlotte Vialle, Marie Chevalerias, Vincent Crenn, Denis Waast, Marie‐Astrid Boutet, Frédéric Blanchard, Benoît Le Goff · 2025 · Cytokine & Growth Factor Reviews
  39. CBL mutation and MEFV single-nucleotide variant are important genetic predictors of tumor reduction in glucocorticoid-treated patients with chronic myelomonocytic leukemia
    Junichi Watanabe, Ken Sato, Yukiko Osawa, Toshikatsu Horiuchi, Shoichiro Kato, Reina Hikota-Saga, Takaaki Maekawa, Takeshi Yamamura, Ayako Kobayashi, Shinichi Kobayashi et al. · 2018 · International Journal of Hematology
  40. CBL knockdown protects cardiomyocytes against hypoxia‑reoxygenation injury by downregulating GRB2 expression
    Zhengbing Lv, Xiaojia Luo, Biying Hong, Qiran Ye, Jianxiong Liu, Yongmei Hu · 2022 · Experimental and Therapeutic Medicine
  41. c-Cbl Regulates Murine Subventricular Zone-Derived Neural Progenitor Cells in Dependence of the Epidermal Growth Factor Receptor
    Maximilian Vogt, Madhukrishna Kolothara Unnikrishnan, Nora Heinig, Ulrike Schumann, Mirko H. H. Schmidt, Kathrin Barth · 2023 · Cells
  42. Effect of CIPC and intervention of Ca2+-regulated factors on CaN, cbl-b and p-AKT expression in neurons
    Yongmei Jiang, Hui Zhang, Lin Yin · 2011 · Brain Research
  43. Effects of RING-SH2^(Grb2), a Chimeric Protein Containing the E3 Ligase Domain of Cbl, on the EGFR Pathway
    Wei Hao Lee · 2014 · The Chinese Journal of Physiology
  44. The Proto-Oncoprotein c-Cbl Protects Cells against Oxidative Stress by Down- Regulating Apoptosis and is Highly Expressed in Several Cancers
    Sadok Yakoub · 2014 · Journal of Cancer Science & Therapy
  45. Interaction of ubiquitin ligase CBL with LMP2A protein of Epstein-Barr virus occurs via PTB domain of CBL and does not depend on adaptor ITSN1
    Oleksandr Dergai, Mykola Dergai, Daria Gudkova, L. O. Tsyba, Inessa Skrypkina, A. V. Rynditch · 2013 · Biopolymers and Cell
  46. Genomic compartmentalization of gene families encoding core components of metazoan signaling systems
    Howard Wong, Jung Soh, Paul M. K. Gordon, Tom Yu, Christoph Wilhelm Sensen, Edward J. Parr, Randal N. Johnston · 2013 · Genome
  47. Juvenile Myelomonocytic Leukemia (JMML)
    Barbaros Şahin Karagün, İlgen Şaşmaz, Bülent Antmen, Yurdanur Kılınç · 2014 · The Journal of Pediatric Research
  48. The Best for the Most Important: Maintaining a Pristine Proteome in Stem and Progenitor Cells
    Bertal Huseyin Aktas, Berin Upcin, Erik Henke, Manju Padmasekar, Xuebin Qin, Süleyman Ergün · 2019 · Stem Cells International
  49. c-Cbl Acts as an E3 Ligase Against DDA3 for Spindle Dynamics and Centriole Duplication during Mitosis.
    Dasom Gwon, Jihee Hong, Chang‐Young Jang · 2019 · Europe PMC (PubMed Central)
  50. Finding meaning in chaos: a selection signature for functional interactions and its use in molecular biology
    Lorin Weiner, Janice L. Brissette · 2022 · FEBS Journal
  51. Downregulation of Src-family tyrosine kinases by Srcasm and c-Cbl: A comparative analysis
    John Seykora, Vivian Lee, ThomasD Griffin, Y Horiuchi, Lily Wushanley, Yerin Kweon, Christine M. Marshall, Weijie Li, Elias E. Ayli, Adele Haimovic et al. · 2021 · Journal of Carcinogenesis
  52. Ubiquitin Signaling and Cancer Pathogenesis
    Kaisa Haglund, Ivan Đikić · 2007 · Wiley eBooks
  53. Small-molecule CBLB inhibitor abolishes EGFR ubiquitination, reduces receptor endocytosis, and diminishes cell motility signaling
    Itziar Pinilla‐Macua, Ratul Mukerji, Frederick Cohen, Alexander D. Sorkin · 2026 · Proceedings of the National Academy of Sciences
  54. Generating Diversity and Specificity through Developmental Cell Signaling
    Renée V. Hoch, Philippe M. Soriano · 2014 · Elsevier eBooks
  55. Management of Two Juvenile Myelomonocytic Leukemia Patients According to Clinical and Genetic Features
    Özlem Tüfekçi, Hale Ören, Fatma Demir Yenigürbüz, Salih Gözmen, Tuba Hilkay Karapınar, Gülersu İrken · 2015 · Turkish Journal of Hematology
  56. Activación de la célula T, alteraciones en el lupus eritematoso sistémico, una revisión narrativa
    Nicolás Téllez Castillo, José J. Siachoque, Juan Sebastian Siachoque Jara, María Alejandra Siachoque Jara, Heber O. Siachoque · 2017 · Revista Colombiana de Reumatología
  57. Current Insights in the Cellular and Molecular Biology of Chronic Myelomonocytic Leukemia
    Raphaël Itzykson, Nathalie M Droin, Éric Solary · 2012 · International Journal of Hematologic Oncology
  58. La régulation du métabolisme du glucose par la protéine tyrosine phosphatase SHP-1
    Sébastien Bergeron · 2007 · Corpus Université Laval (Université Laval)
  59. Signal Transduction by Growth Factor Receptors
    Tony J. Pawson, Claus Jørgensen · 2008 · Elsevier eBooks
  60. Regulation of Tyrosine Kinase Signaling by Cbl in Hematopoietic Stem Cells
    Mayumi Naramura · 2012 · InTech eBooks
  61. B cell signalling in mechanisms of central and peripheral tolerance
    Theresa Thalhamer · 2009 · Enlighten: Theses (The University of Glasgow)
  62. Exploratory pathway analysis
    Thomas Kelder · 2011
  63. Mechanism of ubiquitin transfer by RING E3 ligases
    Hao Dou · 2013 · Enlighten: Theses (The University of Glasgow)
  64. Analyse der Auswirkungen von Aminosäuresubstitutionen im humanen CBL-Protein auf die Regulation des epidermalen Wachstumsfaktorrezeptors (EGFR)
    Hendrik Kentsch · 2012
  65. Negative Regulatory Mechanisms Underlying EPO Receptor Signaling and Erythropoiesis
    Terri D. Richmond · 2010 · TSpace (University of Toronto)
  66. Molecular Mechanism of Ubiquitin-Dependent Traffic
    Elena Maspero, Hans-Peter Wollscheid, Simona Polo · 2013 · Springer eBooks
  67. Analyse der Funktion des humanen Guanin-Nukleotid-Austauschfaktors alphaPIX bei der Regulation des EGF-Rezeptor-Traffickings
    Fanny Kortüm · 2011
  68. Protein Tyrosine Kinases and The Regulation of Signalling and Adhesion in Drosophila melanogaster
    Caroline Grabbe · 2007 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  69. MODULATION OF THE DEUBIQUITINATING SYSTEM IN VIRAL INFECTION, LYMPHOID CELL ACTIVATION AND MALIGNANT TRANSFORMATION
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  70. HER
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  71. Autoimmune Diseases in Childhood
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  72. Application of Next-Generation Sequencing in Noonan Spectrum Disorders
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  73. Immunohistochemical Analysis and Pathological Assessment of B-Cbl Proto-Oncogene in Gastric Carcinoma Cells
    R Salah, Noria Harir, Feriel Sellam, Malika Aidouni, Miloud Medjamia · 2016 · Annals of Cytology and Pathology
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  75. Understanding the Molecular Basis of Juvenile Myelomonocytic Leukemia and Its Application for Novel Drugs Development
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  76. Identification and Characterization of Novel Upstream Regulators of the Hippo Signalling Pathway
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  77. Myeloid Gene Panel Testing with Correlation to Updated Clinical Practice Guidelines
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  79. Regulation von Rezeptor-Tyrosinkinasen durch Opioide
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  80. Intersectins as Novel Protein for Viral Endocytosis- A Mini Review
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  81. Correction: Interaction of c-Cbl with Myosin IIA Regulates Bleb Associated Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus
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  85. CBL ubiquitin ligase targets translation as a degrader E3
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  86. Recherche de nouvelles cibles moléculaires dans les syndromes myélodysplasiques et leucémies aiguës myéloïdes
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