Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.

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Items 801–900 of 1,004

1. Blocking gp130 signaling suppresses autotaxin expression in adipocytes and improves insulin sensitivity in diet-induced obesity
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2. Transcriptional Analysis of FOXO1, C/EBP-α and PPAR-γ2 Genes and Their Association with Obesity-Related Insulin Resistance
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3. Studies on characteristics and anti-diabetic and -nephritic effects of polysaccharides isolated from Paecilomyces hepiali fermentation mycelium in db/db mice
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4. Effect of Spirulina lipids on high-fat and high-sucrose diet induced obesity and hepatic lipid accumulation in C57BL/6J mice
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5. A Critical Review of the Biochemical Mechanisms and Epigenetic Modifications in HIV- and Antiretroviral-Induced Metabolic Syndrome
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6. Obesity-associated proinflammatory cytokines increase calcium sensing receptor (CaSR) protein expression in primary human adipocytes and LS14 human adipose cell line
   Mariana Cifuentes, Cecilia Fuentes, Pamela Mattar, Nicolás Tobar, Eric R. Hugo, Nira Ben‐Jonathan, Cecilia Rojas, Jorge Martı́nez · 2010 · Archives of Biochemistry and Biophysics
7. Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice
   Jun Muratsu, Masaaki Iwabayashi, Fumihiro Sanada, Yoshiaki Taniyama, Rei Otsu, Hiromi Rakugi, Ryuichi Morishita · 2017 · Scientific Reports
8. N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte
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9. Relationship between serum concentrations of persistent organic pollutants and markers of insulin resistance in a cohort of women with a history of gestational diabetes mellitus
   Juan Pedro Arrebola, Amalia González-Jiménez, Constanza Fornieles-González, Francisco Artacho‐Cordón, Nicolás Olea, F. Escobar‐Jiménez, María Luisa Fernández‐Soto · 2014 · Environmental Research
10. Ability Among Adolescents for the Metabolic Syndrome to Predict Elevations in Factors Associated with Type 2 Diabetes and Cardiovascular Disease: Data from the National Health and Nutrition Examination Survey 1999–2006
    Mark Daniel DeBoer, Matthew J. Gurka · 2010 · Metabolic Syndrome and Related Disorders
11. Insight into the Effects of Adipose Tissue Inflammation Factors on miR-378 Expression and the Underlying Mechanism
    Xinye Jiang, Mei Xue, Ziyi Fu, Chenbo Ji, Xirong Guo, Lu Zhu, Lulian Xu, Lingxia Pang, Meiyu Xu, Hongming Qu · 2014 · Cellular Physiology and Biochemistry
12. Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesity
    Ryan G. Toedebusch, Michael D. Roberts, Kevin Dale Wells, Kayla M. Kanosky, Jaume Padilla, Nathan T. Jenkins, James W. Perfield, Jamal A. Ibdah, Frank W. Booth, R. Scott Rector · 2014 · Physiological Genomics
13. MicroRNA-494, Upregulated by Tumor Necrosis Factor-α, Desensitizes Insulin Effect in C2C12 Muscle Cells
    Hyunjoo Lee, Yuna Jee, Kyungki Hong, Gwi Seo Hwang, Kwang‐Hoon Chun · 2013 · PLoS ONE
14. c-Jun regulates adipocyte differentiation via the KLF15-mediated mode
    Da Som Lee, Hyeonjin Choi, Baek‐Soo Han, Won Kon Kim, Sang Chul Lee, Kyoung‐Jin Oh, Kwang‐Hee Bae · 2015 · Biochemical and Biophysical Research Communications
15. Skeletal Muscle Insulin Resistance and Absence of Inflammation Characterize Insulin-Resistant Grade I Obese Women
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16. Additional effect of metformin and celecoxib against lipid dysregulation and adipose tissue inflammation in high-fat fed rats with insulin resistance and fatty liver
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17. Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight
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18. Diabetic human adipose tissue-derived mesenchymal stem cells fail to differentiate in functional adipocytes
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19. Pomegranate juice and its main polyphenols exhibit direct effects on amine oxidases from human adipose tissue and inhibit lipid metabolism in adipocytes
    Francisco Les, Christian Carpéné, José Miguel Arbonés-Mainar, Pauline Decaunes, Marta Sofía Valero, Víctor López · 2017 · Journal of Functional Foods
20. Ingesting Yogurt Containing Lactobacillus plantarum OLL2712 Reduces Abdominal Fat Accumulation and Chronic Inflammation in Overweight Adults in a Randomized Placebo-Controlled Trial
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21. P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice
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22. DNA methylation and gene expression analysis in adipose tissue to identify new loci associated with T2D development in obesity
    Paulina Baca, Francisco Martin Barajas-Olmos, Elaheh Mirzaeicheshmeh, Carlos Zerrweck, Lizbeth Guilbert, Ernesto Carlos Sánchez, Marlen Flores-Huacuja, Rafael Villafán, Angélica Graciela Martínez-Hernández, Humberto Garcia‐Ortíz et al. · 2022 · Nutrition and Diabetes
23. A Difference in Fatty Acid Composition of Isocaloric High-Fat Diets Alters Metabolic Flexibility in Male C57BL/6JOlaHsd Mice
    Loes P. M. Duivenvoorde, Evert M. van Schothorst, Hans J. M. Swarts, Ondřej Kuda, Esther Steenbergh, Sander Termeulen, Ján Kopecký, Jaap Keijer · 2015 · PLoS ONE
24. 6-Hydroxydaidzein Enhances Adipocyte Differentiation and Glucose Uptake in 3T3-L1 Cells
    Li Chen, Qunyi Li, Xiaojin Shi, Shilong Mao, Yongli Du · 2013 · Journal of Agricultural and Food Chemistry
25. Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats
    Qi Zhang, Yingying Tan, Nan Zhang, Fanrong Yao · 2014 · Molecular Medicine Reports
26. Detection of Differential Proteomes Associated with the Development of Type 2 Diabetes in the Zucker Rat Model Using the iTRAQ Technique
    Dohyun Han, Sungyoon Moon, Hyunsoo Kim, Sung‐E Choi, Soojin Lee, Kyong Soo Park, Hee‐Sook Jun, YUP Y. KANG, Youngsoo Kim · 2010 · Journal of Proteome Research
27. Molecular Insights of MAP4K4 Signaling in Inflammatory and Malignant Diseases
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28. Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway
    Yong‐Yu Yang, Jing-Jing Qi, Si-Yi Jiang, Ling Ye · 2023 · Journal of Ethnopharmacology
29. Antidiabetic Screening of Commercial Botanical Products in 3T3-L1 Adipocytes and db/db Mice
    John G. Babish, Linda M. Pacioretty, Jeffrey S. Bland, Deanna M. Minich, Jeffrey Hu, Matthew L. Tripp · 2010 · Journal of Medicinal Food
30. The dark side of browning
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31. Biological Imaging with Medium‐Sensitive Bichromatic Flexible Fluorescent Dyes
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32. Peripheral cannabinoid 1 receptor blockade mitigates adipose tissue inflammation via NLRP3 inflammasome in mouse models of obesity
    Ji Hye Han, Hanho Shin, Jun Gi Rho, Jung‐Eun Kim, Dong H. Son, Juhwan Yoon, Yong Jun Lee, Jung‐Hyuck Park, Byung Joon Song, Chang‐Sik Choi et al. · 2018 · Diabetes Obesity and Metabolism
33. Urolithins: Diet-Derived Bioavailable Metabolites to Tackle Diabetes
    Ana Raimundo, Sofia Ferreira, Francisco Abraham Tomás-Barberán, Cláudia Nunes dos Santos, Regina Menezes · 2021 · Nutrients
34. Anti-inflammatory agents as modulators of the inflammation in adipose tissue: A systematic review
    Sara Sayonara da Cruz Nascimento, Jaluza Luana Carvalho de Queiroz, Amanda Fernandes de Medeiros, Ana Clara de França Nunes, Grasiela Piuvezam, Bruna Leal Lima Maciel, Thaís Souza Passos, Ana Heloneida de Araújo Morais · 2022 · PLoS ONE
35. Ellagitannin geraniin supplementation ameliorates metabolic risks in high-fat diet-induced obese Sprague Dawley rats
    Yin-Sir Chung, So Ha Ton, Sunil Gurtu, Uma Devi Palanisamy · 2014 · Journal of Functional Foods
36. Non-invasive monitoring of cell metabolism and lipid production in 3D engineered human adipose tissues using label-free multiphoton microscopy
    Tyler Chang, Maxwell Zimmerley, Kyle P. Quinn, Isabelle Lamarre, David Lee Kaplan, Emmanuel Beaurepaire, Irene Georgakoudi · 2013 · Biomaterials
37. Probing key targets in insulin signaling and adipogenesis using a methanolic extract of Costus pictus and its bioactive molecule, methyl tetracosanoate
    Kusampudi Shilpa, Kadapakkam Nandabalan Sangeetha, Velusamy Shanmuganathan Muthusamy, S. Sujatha, Baddireddi Subadhra Lakshmi · 2009 · Biotechnology Letters
38. Lipid peroxidation of poly-unsaturated fatty acids in normal and obese adipose tissues
    Guy Cohen, Yael Riahi, Shlomo Sasson · 2011 · Archives of Physiology and Biochemistry
39. Genetic models of PGC-1 and glucose metabolism and homeostasis
    Glenn C. Rowe, Zoltan Pierre Arany · 2013 · Reviews in Endocrine and Metabolic Disorders
40. Low fish oil intake improves insulin sensitivity, lipid profile and muscle metabolism on insulin resistant MSG-obese rats
    Ricardo Key Yamazaki, Gleisson Alisson Pereira de Brito, Isabela Coelho, Danielle Cristina Tonello Pequito, Adriana Aya Yamaguchi, Gina Borghetti, Dalton Luiz Schiessel, Marcelo Kryczyk, Juliano Machado, Ricelli Endrigo Ruppel da Rocha et al. · 2011 · Lipids in Health and Disease
41. Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching
    Ognian Christov Ikonomov, Diego Sbrissa, Khortnal Delvecchio, Han‐Zhong Feng, Gregory D. Cartee, Jian‐Ping Jin, Assia Shisheva · 2013 · American Journal of Physiology-Endocrinology and Metabolism
42. 4-1BB/4-1BBL Interaction Promotes Obesity-Induced Adipose Inflammation by Triggering Bidirectional Inflammatory Signaling in Adipocytes/Macrophages
    Thai Hien Tu, Chu-Sook Kim, Tsuyoshi Goto, Teruo Kawada, Byung-Sam Kim, Rina Yu · 2012 · Mediators of Inflammation
43. Diabetes, Nutrition, and Exercise
    Ahmed H. Abdelhafiz, Alan J. Sinclair · 2015 · Clinics in Geriatric Medicine
44. Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice
    Cheng‐Hsiu Lin, Yueh‐Hsiung Kuo, Chun‐Ching Shih · 2017 · International Journal of Molecular Sciences
45. Epicardial Adipose Tissue: A Novel Potential Imaging Marker of Comorbidities Caused by Chronic Inflammation
    Maria Grazia Tarsitano, Carla Pandozzi, Giuseppe Muscogiuri, Sandro Sironi, Arturo Pujia, Andrea Lenzi, Elisa Giannetta · 2022 · Nutrients
46. TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway
    Seul Gi Lee, Jongbeom Chae, Seon Min Woo, Seung Un Seo, Ha-Jeong Kim, Sang‐Yeob Kim, David D. Schlaepfer, In‐San Kim, Hee-Sae Park, Taeg Kyu Kwon et al. · 2023 · Experimental & Molecular Medicine
47. Obestatin: A new metabolic player in the pancreas and white adipose tissue
    Iacopo Gesmundo, Davide Gallo, Enrica Favaro, Ezio Ghigo, Riccarda Granata · 2013 · IUBMB Life
48. Effects of Black Adzuki Bean (Vigna angularis) Extract on Proliferation and Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes
    Mina K. Kim, Jeong-Eun Park, Seok-Bo Song, Youn‐Soo Cha · 2015 · Nutrients
49. MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling
    Min Jin, Yutao Wu, Jing Wang, Jian Chen, Yiting Huang, Jinpeng Rao, Chun Feng · 2016 · Biochemical and Biophysical Research Communications
50. The Nuclear Receptor Rev-erbα Regulates Adipose Tissue-specific FGF21 Signaling
    Jennifer Jager, Fenfen Wang, Bin Fang, Hee‐Woong Lim, Lindsey C. Peed, David J. Steger, Kyoung‐Jae Won, Alexei Kharitonenkov, Andrew Charles Adams, Mitchell A. Lazar · 2016 · Journal of Biological Chemistry
51. RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
    Adriana‐Mariel Gentile, Said Lhamyani, Leticia Coín‐Aragüez, Wilfredo Oliva‐Olivera, Hatem Zayed, Antonio Pereira Vega, Javier Monteseirı́n, Silvana‐Yanina Romero‐Zerbo, Francisco José Tinahones, Francisco Javier Bermúdez‐Silva et al. · 2016 · PLoS ONE
52. Maresin 1 inhibits TNF‐alpha‐induced lipolysis and autophagy in 3T3‐L1 adipocytes
    Laura M. Laiglesia, Silvia Lorente‐Cebrián, Miguel Lópeź‐Yoldi, Raquel Lanas, Neira Sáinź, José Alfredo Martínez, María Jesús Moreno-Aliaga · 2017 · Journal of Cellular Physiology
53. Endogenous lipid antigens for invariant natural killer T cells hold the reins in adipose tissue homeostasis
    Robert J. van Eijkeren, Olga Krabbe, Marianne L. Boes, Henk S. Schipper, Eric Kalkhoven · 2017 · Immunology
54. TH17 Cell Frequency in Peripheral Blood Is Elevated in Overweight Children without Chronic Inflammatory Diseases
    Theresa Isabell Schindler, Johanna-Josophina Wagner, Sybelle Goedicke‐Fritz, Tobias Rogosch, Verena Coccejus, Verena Laudenbach, Wilfried H. Nikolaizik, Christoph Härtel, Rolf F. Maier, Sebastian Kerzel et al. · 2017 · Frontiers in Immunology
55. Scaffold Proteins: From Coordinating Signaling Pathways to Metabolic Regulation
    Yves Mugabo, Gareth E. Lim · 2018 · Endocrinology
56. Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis
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57. Synthesis, anti-diabetic evaluation and molecular docking studies of 4-(1-aryl-1H-1, 2, 3-triazol-4-yl)-1,4-dihydropyridine derivatives as novel 11-β hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibitors
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58. Oxytocin and Vasopressin Systems in Obesity and Metabolic Health: Mechanisms and Perspectives
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59. The role of mitochondrial oxidative stress in the metabolic alterations in diet‐induced obesity in rats
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60. Adipose tissue as a possible therapeutic target for polyphenols: A case for Cyclopia extracts as anti-obesity nutraceuticals
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61. Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression
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62. RETRACTED: Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice
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63. Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases
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64. RNA-Seq Reveals Function of Bta-miR-149-5p in the Regulation of Bovine Adipocyte Differentiation
    Hongfang Guo, Rajwali Khan, Sayed Haidar Abbas Raza, Syed Muhammad Suhail, Hamayun Khan, Sher Bahadar Khan, Ayman Hassan Abd El-Aziz, Linsen Zan · 2021 · Animals
65. Bioactive dietary components—Anti‐obesity effects related to energy metabolism and inflammation
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66. iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis
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67. Mitochondrial DNA Content in Human Omental Adipose Tissue
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68. DDT and its metabolites are linked to increased risk of type 2 diabetes among Saudi adults: a cross-sectional study
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69. Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study
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71. BCAA dysmetabolism in the host and gut microbiome, a key player in the development of obesity and T2DM
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72. Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program
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73. Effect of a low-starch/low-dairy diet on fat oxidation in overweight and obese women with polycystic ovary syndrome
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74. CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα
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75. The macrophage at the intersection of immunity and metabolism in obesity
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76. Feast and famine: Adipose tissue adaptations for healthy aging
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77. The adipogenic potential of Cr(III). A molecular approach exemplifying metal-induced enhancement of insulin mimesis in diabetes mellitus II
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78. Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women
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79. Global transcriptome profiling identifies KLF15 and SLC25A10 as modifiers of adipocytes insulin sensitivity in obese women
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80. Erratum: Significant association of TREM-1 with HMGB1, TLRs and RAGE in the pathogenesis of insulin resistance in obese diabetic populations.
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81. Function and therapeutic advances of chemokine and its receptor in nonalcoholic fatty liver disease
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82. Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis
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83. Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
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85. Age-Related NAFLD: The Use of Probiotics as a Supportive Therapeutic Intervention
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86. Coenzyme Q10 Prevents Insulin Signaling Dysregulation and Inflammation Prior to Development of Insulin Resistance in Male Offspring of a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth
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87. Lipid droplets hypertrophy: a crucial determining factor in insulin regulation by adipocytes
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88. Activation of the Liver X Receptor by Agonist TO901317 Improves Hepatic Insulin Resistance via Suppressing Reactive Oxygen Species and JNK Pathway
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89. G Protein-coupled receptor kinase 2 (GRK2): A novel modulator of insulin resistance
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90. Beneficial effects of Chlorella on glucose and lipid metabolism in obese rodents on a high-fat diet
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91. Effects of Hyperinsulinemia on Lipolytic Function of Three-Dimensional Adipocyte/Endothelial Co-Cultures
    Jennifer H. K. Choi, Jeffrey M. Gimble, Gordana Vunjak‐Novakovic, David Lee Kaplan · 2010 · Tissue Engineering Part C Methods
92. Basic fibroblast growth factor regulates glucose metabolism through glucose transporter 1 induced by hypoxia-inducible factor-1α in adipocytes
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93. Development of a rapid culture method to induce adipocyte differentiation of human bone marrow-derived mesenchymal stem cells
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94. Distinct gene expression profiles characterize cellular responses to palmitate and oleate
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95. Aptamers: novel diagnostic and therapeutic tools for diabetes mellitus and metabolic diseases
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96. Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues
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97. 5,7-Dimethoxyflavone Attenuates Obesity by Inhibiting Adipogenesis in 3T3-L1 Adipocytes and High-Fat Diet-Induced Obese C57BL/6J Mice
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98. Cycling our way to fit fat
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99. Gene expression profile of subcutaneous adipose tissue in BMI-discordant monozygotic twin pairs unravels molecular and clinical changes associated with sub-types of obesity
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