The DOI matches its Crossref record; 140 of the 140 references it cites were found in a registry or an index.
Heat shock factors: integrators of cell stress, development and lifespan
Open accessAbstract
Heat shock factors (HSFs) are essential for all organisms to survive exposures to acute stress. They are best known as inducible transcriptional regulators of genes encoding molecular chaperones and other stress proteins. Four members of the HSF family are also important for normal development and lifespan-enhancing pathways, and the repertoire of HSF targets has thus expanded well beyond the heat shock genes. These unexpected observations have uncovered complex layers of post-translational regulation of HSFs that integrate the metabolic state of the cell with stress biology, and in doing so control fundamental aspects of the health of the proteome and ageing.
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Cites
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A new puffing pattern induced by temperature shock and DNP in drosophila
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Self-citationSteroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*
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Regulation of aging and age-related disease by DAF-16 and heat-shock factor
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Heat Shock Transcription Factors: Structure and Regulation
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“Subsequent studies showed that, in contrast to a single HSF in invertebrates, multiple HSFs are expressed in plants and vertebrate”
Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
Powers, E. T., Morimoto, R. I., Dillin, A., Kelly, J. W., & Balch, W. E. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.114844 · Cited by 1,149
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Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265
Multi-Omics Factor Analysis—a framework for unsupervised integration of multi-omics data sets
Argelaguet, R., Velten, B., Arnol, D., Dietrich, S., Zenz, T., Marioni, J. C., Buettner, F., Huber, W., & Stegle, O. (2018) · Molecular Systems Biology · doi:10.15252/msb.20178124 · Cited by 1,510
The Biology of Proteostasis in Aging and Disease
Labbadia, J., & Morimoto, R. I. (2015) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060614-033955 · Cited by 1,472
Self-citationFever and the thermal regulation of immunity: the immune system feels the heat
Evans, S. S., Repasky, E. A., & Fisher, D. T. (2015) · Nature Reviews Immunology · doi:10.1038/nri3843 · Cited by 1,257
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Metadata
- Authors
- Åkerfelt, M., Morimoto, R. I., & Sistonen, L.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2010-07-14
- Volume
- 11
- Issue
- 8
- Pages
- 545-555
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2040359453
- Cited by
- 1,455
- References
- 140
- FWCI
- 4.26
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
