Central and Peripheral Circadian Clocks in Mammals

Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1

Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., Spiegelman, B. M., & Puigserver, P. (2005) · Nature · doi:10.1038/nature03354 · Cited by 3,160 · see citing works

Obesity and Metabolic Syndrome in Circadian <i>Clock</i> Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485 · see citing works

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421 · see citing works

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes &amp; Development · doi:10.1101/gad.183500 · Cited by 2,394 · see citing works

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329 · see citing works

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,272 · see citing works

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198 · see citing works

Metabolic control through the PGC-1 family of transcription coactivators

Lin, J., Handschin, C., & Spiegelman, B. M. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.05.004 · Cited by 2,130 · cited 1× · see citing works

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Balsalobre, A., Damiola, F., & Schibler, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81199-x · Cited by 2,001 · see citing works

Circadian integration of metabolism and energetics

Bass, J., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195027 · Cited by 1,910 · see citing works

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907 · see citing works

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859 · see citing works

Transplanted Suprachiasmatic Nucleus Determines Circadian Period

Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853 · see citing works

Entrainment of the circadian clock in the liver by feeding

Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800 · see citing works

The genetics of mammalian circadian order and disorder: implications for physiology and disease

Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2430 · Cited by 1,611 · see citing works

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms.

Welsh, D. K., Logothetis, D., Meister, M., & Reppert, S. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,535 · see citing works

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

Marcheva, B., Ramsey, K. M., Buhr, E. D., Kobayashi, Y., Su, H., Ko, C. H., Ivanova, G., Omura, C., Mo, S., Vitaterna, M. H., et al. (2010) · Nature · doi:10.1038/nature09253 · Cited by 1,525 · see citing works

Extensive and divergent circadian gene expression in liver and heart

Storch, K.-F., Lipan, O., Leykin, I., Viswanathan, N., Davis, F. C., Wong, W. H., & Weitz, C. J. (2002) · Nature · doi:10.1038/nature744 · Cited by 1,509 · see citing works

Heat shock factors: integrators of cell stress, development and lifespan

Åkerfelt, M., Morimoto, R. I., & Sistonen, L. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2938 · Cited by 1,457 · see citing works

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D., Guarente, L. P., & Sassone-Corsi, P. (2008) · Cell · doi:10.1016/j.cell.2008.07.002 · Cited by 1,427 · see citing works

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., Mostoslavsky, R., Alt, F. W., & Schibler, U. (2008) · Cell · doi:10.1016/j.cell.2008.06.050 · Cited by 1,376 · see citing works

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

Welsh, D. K., Takahashi, J. S., & Kay, S. A. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135919 · Cited by 1,216 · see citing works

Circadian Control of the NAD ⁺ Salvage Pathway by CLOCK-SIRT1

Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M., & Sassone-Corsi, P. (2009) · Science · doi:10.1126/science.1170803 · Cited by 1,198 · see citing works

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD ⁺ Biosynthesis

Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., Hong, H.-K., Chong, J. L., Buhr, E. D., Lee, C., et al. (2009) · Science · doi:10.1126/science.1171641 · Cited by 1,126 · see citing works

A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock

Sato, T. K., Panda, S., Miraglia, L. J., Reyes, T. M., Rudic, R. D., McNamara, P., Naik, K. A., FitzGerald, G. A., Kay, S. A., & Hogenesch, J. B. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.018 · Cited by 1,115 · see citing works

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

Rutter, J., Reick, M., Wu, L. C., & McKnight, S. L. (2001) · Science · doi:10.1126/science.1060698 · Cited by 1,059 · see citing works

Physiological significance of a peripheral tissue circadian clock

Lamia, K. A., Storch, K.-F., & Weitz, C. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806717105 · Cited by 1,048 · see citing works

Circadian Gene Expression in Individual Fibroblasts

Nagoshi, E., Saini, C., Bauer, C. R., Laroche, T., Naef, F., & Schibler, U. (2004) · Cell · doi:10.1016/j.cell.2004.11.015 · Cited by 1,003 · see citing works

Mammalian circadian biology: elucidating genome-wide levels of temporal organization

Lowrey, P. L., & Takahashi, J. S. (2004) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.5.061903.175925 · Cited by 976 · see citing works

AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation

Lamia, K. A., Sachdeva, U. M., DiTacchio, L., Williams, E. C., Alvarez, J. G., Egan, D. F., Vasquez, D. S., Juguilon, H., Panda, S., Shaw, R. J., et al. (2009) · Science · doi:10.1126/science.1172156 · Cited by 958 · see citing works

Nuclear Receptor Expression Links the Circadian Clock to Metabolism

Yang, X., Downes, M., Yu, R. T., Bookout, A. L., He, W., Straume, M., Mangelsdorf, D. J., & Evans, R. M. (2006) · Cell · doi:10.1016/j.cell.2006.06.050 · Cited by 934 · see citing works

Synchronization of Cellular Clocks in the Suprachiasmatic Nucleus

Yamaguchi, S., Isejima, H., Matsuo, T., Okura, R., Yagita, K., Kobayashi, M., & Okamura, H. (2003) · Science · doi:10.1126/science.1089287 · Cited by 934 · see citing works

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195262 · Cited by 917 · see citing works

The Meter of Metabolism

Green, C. B., Takahashi, J. S., & Bass, J. (2008) · Cell · doi:10.1016/j.cell.2008.08.022 · Cited by 902 · cited 2× · see citing works

Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision

Güler, A. D., Ecker, J. L., Lall, G. S., Haq, S., Altimus, C. M., Liao, H., Barnard, A. R., Cahill, H. B., Badea, T. C., Zhao, H., et al. (2008) · Nature · doi:10.1038/nature06829 · Cited by 872 · see citing works

A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms

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Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

Akhtar, R. A., Reddy, A. B., Maywood, E. S., Clayton, J. D., King, V. M., Smith, A. G., Gant, T. W., Hastings, M. H., & Kyriacou, C. P. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00759-5 · Cited by 777 · see citing works

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression.

Vollmers, C., Gill, S., DiTacchio, L., Pulivarthy, S. R., Le, H. D., & Panda, S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909591106 · Cited by 765 · see citing works

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.057 · Cited by 726 · see citing works

Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

Liu, A. C., Welsh, D. K., Ko, C. H., Tran, H. G., Zhang, E. E., Priest, A. A., Buhr, E. D., Singer, O., Meeker, K., Verma, I. M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.02.047 · Cited by 694 · see citing works

Harmonics of Circadian Gene Transcription in Mammals

Hughes, M. E., DiTacchio, L., Hayes, K. R., Vollmers, C., Pulivarthy, S. R., Baggs, J. E., Panda, S., & Hogenesch, J. B. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000442 · Cited by 674 · see citing works

The “other” circadian system: food as a Zeitgeber

Stephan, F. K. (2002) · Journal of Biological Rhythms · doi:10.1177/074873002129002591 · Cited by 672 · see citing works

System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., & Schibler, U. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050034 · Cited by 658 · see citing works

Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism

Liu, C., Li, S., Liu, T., Borjigin, J., & Lin, J. D. (2007) · Nature · doi:10.1038/nature05767 · Cited by 643 · see citing works

Light activates the adrenal gland: Timing of gene expression and glucocorticoid release

Ishida, A., Mutoh, T., Ueyama, T., Bando, H., Masubuchi, S., Nakahara, D., Tsujimoto, G., & Okamura, H. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.09.009 · Cited by 589 · see citing works

Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks

Brown, S. A., Zumbrunn, G., Fleury-Olela, F., Preitner, N., & Schibler, U. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01145-4 · Cited by 589 · see citing works

Genetics of Circadian Rhythms in Mammalian Model Organisms

Lowrey, P. L., & Takahashi, J. S. (2011) · Advances in genetics · doi:10.1016/b978-0-12-387690-4.00006-4 · Cited by 578 · see citing works

Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus

Hara, R., Wan, K., Wakamatsu, H., Aida, R., Moriya, T., Akiyama, M., & Shibata, S. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00419.x · Cited by 569 · cited 1× · see citing works

Intrinsically photosensitive retinal ganglion cells: many subtypes, diverse functions

Schmidt, T. M., Chen, S., & Hattar, S. S. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.07.001 · Cited by 553 · see citing works

The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock

Oster, H., Damerow, S., Kiessling, S., Jakubcakova, V., Abraham, D., Tian, J., Hoffmann, M. W., & Eichele, G. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.07.002 · Cited by 528 · see citing works

The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification

Gachon, F., Fleury-Olela, F., Schaad, O., Descombes, P., & Schibler, U. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.04.015 · Cited by 511 · see citing works

Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation

Miller, B. H., McDearmon, E. L., Panda, S., Hayes, K. R., Zhang, J., Andrews, J. L., Antoch, M. P., Walker, J. R., Esser, K. A., Hogenesch, J. B., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611724104 · Cited by 509 · see citing works

Cellular Construction of a Circadian Clock: Period Determination in the Suprachiasmatic Nuclei

Liu, C., Weaver, D. R., Strogatz, S. H., & Reppert, S. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80473-0 · Cited by 508 · see citing works

Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway

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Intrinsically Photosensitive Retinal Ganglion Cells

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Molecular Mechanisms of the Biological Clock in Cultured Fibroblasts

Yagita, K., Tamanini, F., van der Horst, G. T. J., & Okamura, H. (2001) · Science · doi:10.1126/science.1059542 · Cited by 464 · see citing works

The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms

Gooley, J. J., Schomer, A., & Saper, C. B. (2006) · Nature Neuroscience · doi:10.1038/nn1651 · Cited by 453 · see citing works

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

Martelot, G. L., Claudel, T., Gatfield, D., Schaad, O., Kornmann, B., Sasso, G. L., Moschetta, A., & Schibler, U. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000181 · Cited by 448 · see citing works

Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs

Chen, S., Badea, T. C., & Hattar, S. S. (2011) · Nature · doi:10.1038/nature10206 · Cited by 436 · see citing works

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

So, A. Y.-L., Bernal, T. U., Pillsbury, M. L., Yamamoto, K. R., & Feldman, B. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909733106 · Cited by 431 · see citing works

Metabolism and the Control of Circadian Rhythms

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A behavioristic study of the activity of the rat,

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The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

Schmutz, I., Ripperger, J. A., Baeriswyl-Aebischer, S., & Albrecht, U. (2010) · Genes &amp; Development · doi:10.1101/gad.564110 · Cited by 361 · see citing works

Reciprocal Regulation of Brain and Muscle Arnt-Like Protein 1 and Peroxisome Proliferator-Activated Receptor α Defines a Novel Positive Feedback Loop in the Rodent Liver Circadian Clock

Canaple, L., Rambaud, J., Dkhissi‐Benyahya, O., Rayet, B., Tan, N. S., Michalik, L., Delaunay, F., Wahli, W., & Laudet, V. (2006) · Molecular Endocrinology · doi:10.1210/me.2006-0052 · Cited by 353 · see citing works

Coupling governs entrainment range of circadian clocks

Abraham, U., Granada, A. E., Westermark, P. O., Heine, M., Kramer, A., & Herzel, H. (2010) · Molecular Systems Biology · doi:10.1038/msb.2010.92 · Cited by 349 · see citing works

Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding

Asher, G., Reinke, H., Altmeyer, M., Gutierrez-Arcelus, M., Hottiger, M. O., & Schibler, U. (2010) · Cell · doi:10.1016/j.cell.2010.08.016 · Cited by 340 · see citing works

Circadian Programs of Transcriptional Activation, Signaling, and Protein Turnover Revealed by Microarray Analysis of Mammalian Cells

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Neurons and networks in daily rhythms

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Acute Physical Stress Elevates Mouse Period1 mRNA Expression in Mouse Peripheral Tissues via a Glucocorticoid-responsive Element

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Suprachiasmatic Nuclear Lesions Do Not Abolish Food-Shifted Circadian Adrenal and Temperature Rhythmicity

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Entrainment of circadian rhythms by feeding schedules in rats with suprachiasmatic lesions

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Temporal Precision in the Mammalian Circadian System: A Reliable Clock from Less Reliable Neurons

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Separate oscillating cell groups in mouse suprachiasmatic nucleus couple photoperiodically to the onset and end of daily activity

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Glucocorticoid signaling synchronizes the liver circadian transcriptome

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Differential control of peripheral circadian rhythms by suprachiasmatic-dependent neural signals

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Seasonal Encoding by the Circadian Pacemaker of the SCN

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Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver

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Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

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Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids.

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Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factorPreprint

Reinke, H., Saini, C., Fleury-Olela, F., Dibner, C., Benjamin, I. J., & Schibler, U. (2008) · Genes & Development · doi:10.1101/gad.453808 · Cited by 228 · see citing works

The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase–response curve amplitude

Vitaterna, M. H., Ko, C. H., Chang, A., Buhr, E. D., Fruechte, E. M., Schook, A. C., Antoch, M. P., Turek, F. W., & Takahashi, J. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603601103 · Cited by 222 · see citing works

Daily rhythms of food-anticipatory behavioral activity do not require the known circadian clock

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Emergence of Noise-Induced Oscillations in the Central Circadian Pacemaker

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Adrenal Sensitivity to Adrenocorticotropin Varies Diurnally*

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The suprachiasmatic nucleus controls the daily variation of plasma glucose via the autonomic output to the liver: are the clock genes involved?

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Suprachiasmatic nucleus: a central autonomic clock

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Is the food‐entrainable circadian oscillator in the digestive system?

Davidson, A. J., Poole, A. S., Yamazaki, S., & Menaker, M. (2003) · Genes Brain & Behavior · doi:10.1034/j.1601-183x.2003.00005.x · Cited by 180 · see citing works

Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats

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The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

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The Plant Circadian Clock: From a Simple Timekeeper to a Complex Developmental ManagerPreprint

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O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination

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Cold-inducible proteins CIRP and RBM3, a unique couple with activities far beyond the cold

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The circadian timing system in clinical oncology

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Circadian Oscillators: Around the Transcription–Translation Feedback Loop and on to Output

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mTOR signaling regulates central and peripheral circadian clock function

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

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<i>Chi3l1</i> /YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis

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Regulation of the Blood–Brain Barrier by Circadian Rhythms and Sleep

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Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

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Extensive Oscillatory Gene Expression during C. elegans Larval Development

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The Association between Chronotype and Dietary Pattern among Adults: A Scoping Review

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Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1‐BMAL1 pathway

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A sleep-inducing gene, nemuri , links sleep and immune function in Drosophila

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How to fix a broken clock

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The Mammalian Circadian Timing System: Synchronization of Peripheral ClocksPreprint

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The Nervous System

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The mammalian circadian timing system: from gene expression to physiology

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