The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Tail-anchored membrane protein insertion into the endoplasmic reticulum
Open accessAbstract
Membrane proteins are inserted into the endoplasmic reticulum (ER) by two highly conserved parallel pathways. The well-studied co-translational pathway uses signal recognition particle (SRP) and its receptor for targeting and the SEC61 translocon for membrane integration. A recently discovered post-translational pathway uses an entirely different set of factors involving transmembrane domain (TMD)-selective cytosolic chaperones and an accompanying receptor at the ER. Elucidation of the structural and mechanistic basis of this post-translational membrane protein insertion pathway highlights general principles shared between the two pathways and key distinctions unique to each.
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“, and mutant phenotypes in other organisms were related to processes that involved TA protein”
Cited by
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Self-citationA YidC-like protein in the archaeal plasma membrane.
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Metadata
- Authors
- Hegde, R. S., & Keenan, R. J.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2011-11-16
- Volume
- 12
- Issue
- 12
- Pages
- 787-798
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2053673239
- Cited by
- 262
- References
- 115
- FWCI
- 1.11
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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