The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
Clinical and biological insights from viral genome sequencing
Open accessAbstract
Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice. In virology, WGS is important for the development of novel treatments and vaccines, and for increasing the power of molecular epidemiology and evolutionary genomics. In this Opinion article, we suggest that WGS of viruses in a clinical setting will become increasingly important for patient care. We give an overview of different WGS methods that are used in virology and summarize their advantages and disadvantages. Although there are only partially addressed technical, financial and ethical issues in regard to the clinical application of viral WGS, this technique provides important insights into virus transmission, evolution and pathogenesis.
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Cites
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Cited by
Quick, J., Grubaugh, N. D., Pullan, S. T., Claro, I. M., Smith, A. D., Gangavarapu, K., Oliveira, G., Robles-Sikisaka, R., Rogers, T. F., Beutler, N. A., et al. (2017) · Nature Protocols · doi:10.1038/nprot.2017.066 · Cited by 1,190
Massively multiplexed nucleic acid detection with Cas13
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Towards a genomics-informed, real-time, global pathogen surveillance system
Gardy, J. L., & Loman, N. J. (2018) · Nature Reviews Genetics · doi:10.1038/nrg.2017.88 · Cited by 771
Minimum Information about an Uncultivated Virus Genome (MIUViG)
Roux, S., Adriaenssens, E. M., Dutilh, B. E., Koonin, E. V., Kropinski, A. M., Krupovic, M., Kuhn, J. H., Lavigne, R., Brister, J. R., Varsani, A., et al. (2019) · Nature Biotechnology · doi:10.1038/nbt.4306 · Cited by 732
Meredith, L. W., Hamilton, W. L., Warne, B., Houldcroft, C. J., Hosmillo, M., Jahun, A. S., Curran, M. D., Parmar, S., Caller, L. G., Caddy, S. L., et al. (2020) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(20)30562-4 · Cited by 389
Self-citation
Metadata
- Authors
- Houldcroft, C. J., Beale, M. A., & Breuer, J.
- Venue
- Nature Reviews Microbiology
- Published
- 2017-01-16
- Volume
- 15
- Issue
- 3
- Pages
- 183-192
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2579012589
- Cited by
- 334
- References
- 114
- FWCI
- 2.31
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
