The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Reconstruction of biochemical networks in microorganisms
Open accessAbstract
Systems analysis of metabolic and growth functions in microbial organisms is rapidly developing and maturing. Such studies are enabled by reconstruction, at the genomic scale, of the biochemical reaction networks that underlie cellular processes. The network reconstruction process is organism specific and is based on an annotated genome sequence, high-throughput network-wide data sets and bibliomic data on the detailed properties of individual network components. Here we describe the process that is currently used to achieve comprehensive network reconstructions and discuss how these reconstructions are curated and validated. This Review should aid the growing number of researchers who are carrying out reconstructions for particular target organisms.
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Cites
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Self-citationBiGG Models: A platform for integrating, standardizing and sharing genome-scale models
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Self-citationConstraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods
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Metadata
- Authors
- Feist, A. M., Herrgård, M. J., Thiele, I., Reed, J. L., & Palsson, B. Ø.
- Venue
- Nature Reviews Microbiology
- Published
- 2008-12-31
- Volume
- 7
- Issue
- 2
- Pages
- 129-143
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2126175129
- Cited by
- 859
- References
- 13
- FWCI
- 4.04
- Type
- journal article
- Language
- en
- Open access
- green
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- Feist, A. M., Herrgård, M. J., Thiele, I., Reed, J. L., & Palsson, B. Ø. (2009). Reconstruction of biochemical networks in microorganisms. Nature Reviews Microbiology. https://doi.org/10.1038/nrmicro1949
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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