The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The type III secretion system of Pseudomonas aeruginosa: infection by injection
Open accessAbstract
The Gram-negative bacterium Pseudomonas aeruginosa uses a complex type III secretion apparatus to inject effector proteins into host cells. The configuration of this secretion machinery, the activities of the proteins that are injected by it and the consequences of this process for infection are now being elucidated. This Review summarizes our current knowledge of P. aeruginosa type III secretion, including the secretion and translocation machinery, the regulation of this machinery, and the associated chaperones and effector proteins. The features of this interesting secretion system have important implications for the pathogenesis of P. aeruginosa infections and for other type III secretion systems.
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“P. aeruginosa employs several secretion systems, including the type III secretion system (T3SS), which injects toxins directly into host cells110,111.”
From Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility (2025) · cites this paper as [110]
In the citing paper
“The expression of the T3SS is tightly regulated by environmental signals110,111, allowing P. aeruginosa to deploy this system when in contact with host cells.”
From Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility (2025) · cites this paper as [110]
In the citing paper
“These toxins, including ExoU, ExoT, ExoS and ExoY, have distinct functions that disrupt normal cellular processes110.”
From Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility (2025) · cites this paper as [110]
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Cites
Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia
Kurahashi, K., Kajikawa, O., Sawa, T., Ohara, M., Gropper, M. A., Frank, D. W., Martin, T. R., & Wiener-Kronish, J. P. (1999) · Journal of Clinical Investigation · doi:10.1172/jci7124 · Cited by 316
Cited by
Soil enzymes in a changing environment: Current knowledge and future directions
Burns, R. G., DeForest, J. L., Marxsen, J., Sinsabaugh, R. L., Stromberger, M. E., Wallenstein, M. D., Weintraub, M. N., & Zoppini, A. (2013) · Soil Biology and Biochemistry · doi:10.1016/j.soilbio.2012.11.009 · Cited by 2,552
Qin, S., Xiao, W., Zhou, C., Pu, Q., Deng, X., Lan, L., Liang, H., Song, X., & Wu, M. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01056-1 · Cited by 1,703
Pseudomonas aeruginosa : new insights into pathogenesis and host defenses
Gellatly, S. L., & Hancock, R. E. W. (2013) · Pathogens and Disease · doi:10.1111/2049-632x.12033 · Cited by 1,295
Pseudomonas genomes: diverse and adaptable
Silby, M. W., Winstanley, C., Godfrey, S. A. C., Levy, S. B., & Jackson, R. W. (2011) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00269.x · Cited by 960
The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update
Reynolds, D., & Kollef, M. (2021) · Drugs · doi:10.1007/s40265-021-01635-6 · Cited by 721
Metadata
- Authors
- Hauser, A. R.
- Venue
- Nature Reviews Microbiology
- Published
- 2009-09
- Volume
- 7
- Issue
- 9
- Pages
- 654-665
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2067906280
- Cited by
- 968
- References
- 1
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
