The DOI matches its Crossref record; 154 of the 154 references it cites were found in a registry or an index.
Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina
Open accessAbstract
In the developing vertebrate retina, diverse neuronal subtypes originate from multipotent progenitors in a conserved order and are integrated into an intricate laminated architecture. Recent progress in mammalian photoreceptor development has identified a complex relationship between six key transcription-regulatory factors (RORbeta, OTX2, NRL, CRX, NR2E3 and TRbeta2) that determine rod versus M cone or S cone cell fate. We propose a step-wise 'transcriptional dominance' model of photoreceptor cell fate determination, with the S cone representing the default state of a generic photoreceptor precursor. Elucidation of gene-regulatory networks that dictate photoreceptor genesis and homeostasis will have wider implications for understanding the development of nervous system function and for the treatment of neurodegenerative diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Certain differentiation gene batteries composed of orthologous effector genes and the regulatory state drivers that activate them are known in all bilaterian animals investigated and even in cnidarians, e.g., in muscle cells (5) neurons (13), photoreceptor cells (14 -17), and neurosecretory cells (17).”
From Transphyletic conservation of developmental regulatory state in animal evolution (2011) · cites this paper as [16]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Human photoreceptor topography
Curcio, C. A., Sloan, K. R., Kalina, R. E., & Hendrickson, A. E. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902920402 · Cited by 2,894
Exome sequencing identifies the cause of a mendelian disorder
Ng, S. B., Buckingham, K. J., Lee, C., Bigham, A. W., Tabor, H. K., Dent, K. M., Huff, C. D., Shannon, P. T., Jabs, E. W., Nickerson, D. A., et al. (2010) · Nature Genetics · doi:10.1038/ng.499 · Cited by 1,957
Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red Pigments
Nathans, J., Thomas, D., & Hogness, D. S. (1986) · Science · doi:10.1126/science.2937147 · Cited by 1,734
Parallel processing in the mammalian retina
Wässle, H. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1497 · Cited by 1,253
The fundamental plan of the retina
Masland, R. H. (2001) · Nature Neuroscience · doi:10.1038/nn0901-877 · Cited by 1,247
The Retina: An Approachable Part of the Brain
(1989) · Archives of Ophthalmology · doi:10.1001/archopht.1989.01070020357018 · Cited by 1,124
Retinal repair by transplantation of photoreceptor precursors
MacLaren, R. E., Pearson, R. A., MacNeil, A., Douglas, R. H., Salt, T. E., Akimoto, M., Swaroop, A., Sowden, J. C., & Ali, R. R. (2006) · Nature · doi:10.1038/nature05161 · Cited by 1,108
Self-citationCell differentiation in the retina of the mouse
Young, R. W. (1985) · The Anatomical Record · doi:10.1002/ar.1092120215 · Cited by 1,086
The arrangement of the three cone classes in the living human eye
Roorda, A., & Williams, D. R. (1999) · Nature · doi:10.1038/17383 · Cited by 1,004
Cell fate determination in the vertebrate retina.
Cepko, C. L., Austin, C. P., Yang, X.-J., Alexiades, M. R., & Ezzeddine, D. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.2.589 · Cited by 989
Cited by
Sorted by citations
Evolution of Gene Regulatory Networks Controlling Body Plan Development
Peter, I. S., & Davidson, E. H. (2011) · Cell · doi:10.1016/j.cell.2011.02.017 · Cited by 417
Evolution of phototransduction, vertebrate photoreceptors and retina
Lamb, T. D. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.06.001 · Cited by 400
Chemistry of the Retinoid (Visual) Cycle
Kiser, P. D., Golczak, M., & Palczewski, K. (2014) · Chemical Reviews · doi:10.1021/cr400107q · Cited by 353
Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types
Yan, W., Laboulaye, M. A., Tran, N. M., Whitney, I. E., Benhar, I., & Sanes, J. R. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0471-20.2020 · Cited by 343
Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish
Lenkowski, J. R., & Raymond, P. A. (2014) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.12.007 · Cited by 333
Metadata
- Authors
- Swaroop, A., Kim, D., & Forrest, D.
- Affiliations
- National Institutes of Health (US)
- National Institute of Diabetes and Digestive and Kidney Diseases (US)
- Corresponding author
- Swaroop, Anand
- Venue
- Nature Reviews Neuroscience
- Published
- 2010-08
- Volume
- 11
- Issue
- 8
- Pages
- 563-576
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- PMC
- PMC11346175
- OpenAlex
- W2067470032
- Cited by
- 560
- References
- 154
- Citations by year
- 2026: 25 · 2025: 39 · 2024: 34 · 2023: 34 · 2022: 31 · 2021: 35 · 2020: 38 · 2019: 38 · 2018: 36 · 2017: 38 · 2016: 40 · 2015: 32 · 2014: 35 · 2013: 42 · 2012: 30
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Eye Institute (ZIAEY000473, Z01EY000450, ZIAEY000546)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- photoreceptor development, transcriptional regulation, retina, S-cones, rod photoreceptors, M-cones, transcription factors, RORβ, Otx2, NRL, CRX, NR2E3, TRbeta2, gene regulatory networks
- MeSH terms
- Animals, Homeostasis, Humans, Photoreceptor Cells, Retina, Retinal Diseases, Transcription, Genetic, Apoptosis, Neurogenesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
