The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.
Acid-sensing ion channels in pain and disease
Open accessAbstract
Why do neurons sense extracellular acid? In large part, this question has driven increasing investigation on acid-sensing ion channels (ASICs) in the CNS and the peripheral nervous system for the past two decades. Significant progress has been made in understanding the structure and function of ASICs at the molecular level. Studies aimed at clarifying their physiological importance have suggested roles for ASICs in pain, neurological and psychiatric disease. This Review highlights recent findings linking these channels to physiology and disease. In addition, it discusses some of the implications for therapy and points out questions that remain unanswered.
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A proton-gated cation channel involved in acid-sensing
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Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH
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Self-citationThe Acid-Activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory
Wemmie, J. A., Chen, J., Askwith, C. C., Hruska-Hageman, A. M., Price, M. P., Nolan, B. C., Yoder, P. G., Lamani, E., Hoshi, T., Freeman, J. H., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00661-x · Cited by 657
Self-citationThe DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice
Price, M. P., McIlwrath, S. L., Xie, J., Cheng, C., Qiao, J., Tarr, D. E., Sluka, K. A., Brennan, T. J., Lewin, G. R., & Welsh, M. J. (2001) · Neuron · doi:10.1016/s0896-6273(01)00547-5 · Cited by 604
Acid-sensing ion channels: advances, questions and therapeutic opportunities
Wemmie, J. A., Price, M. P., & Welsh, M. J. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.06.014 · Cited by 559
Self-citationA receptor for protons in the nerve cell membrane
Krishtal, O. A., & Pidoplichko, V. I. (1980) · Neuroscience · doi:10.1016/0306-4522(80)90149-9 · Cited by 536
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The mammalian sodium channel BNC1 is required for normal touch sensation
Price, M. P., Lewin, G. R., McIlwrath, S. L., Cheng, C., Xie, J., Heppenstall, P. A., Stucky, C. L., Mannsfeldt, A. G., Brennan, T. J., Drummond, H. A., et al. (2000) · Nature · doi:10.1038/35039512 · Cited by 508
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Friese, M. A., Schattling, B., & Fugger, L. (2014) · Nature Reviews Neurology · doi:10.1038/nrneurol.2014.37 · Cited by 628
Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala
Du, J., Reznikov, L. R., Price, M. P., Zha, X.-M., Lu, Y., Moninger, T. O., Wemmie, J. A., & Welsh, M. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1407018111 · Cited by 277
Self-citationCathepsins: Proteases that are vital for survival but can also be fatal
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Metadata
- Authors
- Wemmie, J. A., Taugher, R. J., & Kreple, C. J.
- Venue
- Nature Reviews Neuroscience
- Published
- 2013-06-20
- Volume
- 14
- Issue
- 7
- Pages
- 461-471
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W2085805107
- Cited by
- 606
- References
- 138
- FWCI
- 6.05
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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