Genetic, environmental, and epigenetic factors involved in CAKUT

Nicolaou, Nayia, Renkema, Kirsten Y., Bongers, Ernie M. H. F., Giles, Rachel H., Knoers, Nine V. A. M.·2015·Nature Reviews Nephrology

Cited by (346)

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  5. Clinical, laboratory, imaging features and prognosis in pediatric patients with Congenital anomalies of the kidney and the urinary tract (CAKUT): a referral center experience
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  10. Additional file 3 of GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
    Xuanjin Du, C N Wang, Liu, Jialu, Yu, Minghui, Haixin Ju, Shanshan Xue, Li, Yaxin, Liu, Jiaojiao, Rufeng Dai, Chen, Jing et al. · 2024 · Figshare
  11. Additional file 4 of GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
    Xuanjin Du, C N Wang, Liu, Jialu, Yu, Minghui, Haixin Ju, Shanshan Xue, Li, Yaxin, Liu, Jiaojiao, Rufeng Dai, Chen, Jing et al. · 2024 · Figshare
  12. Additional file 1 of GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
    Xuanjin Du, C N Wang, Liu, Jialu, Yu, Minghui, Haixin Ju, Shanshan Xue, Li, Yaxin, Liu, Jiaojiao, Rufeng Dai, Chen, Jing et al. · 2024 · Figshare
  13. Additional file 1 of Molecular causes of congenital anomalies of the kidney and urinary tract (CAKUT)
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  14. Additional file 1 of Clinical outcomes and temporal trends of immunological and non-immunological rare diseases in adult kidney transplant
    Ester Gallo, Silvia Mingozzi, Alberto Mella, Fabrizio Fop, Roberto Presta, Manuel Burdese, Elena Boaglio, Maria Cristina Torazza, Roberta Giraudi, Gianluca Leonardi et al. · 2021 · Figshare
  15. Additional file 6 of GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
    Xuanjin Du, C N Wang, Liu, Jialu, Yu, Minghui, Haixin Ju, Shanshan Xue, Li, Yaxin, Liu, Jiaojiao, Rufeng Dai, Jing Chen et al. · 2024 · Figshare
  16. Additional file 1 of A preliminary study of the miRNA restitution effect on CNV-induced miRNA downregulation in CAKUT
    Kristina Mitrovic, Ivan Životić, Ivana Kolić, Jelena J. Žakula, Zivkovic, Maja, Stankovic, Aleksandra, Ivan B. Jovanović · 2024 · Figshare
  17. Additional file 2 of GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
    Xuanjin Du, C N Wang, Liu, Jialu, Yu, Minghui, Haixin Ju, Shanshan Xue, Li, Yaxin, Liu, Jiaojiao, Rufeng Dai, Chen, Jing et al. · 2024 · Figshare
  18. Additional file 5 of GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
    Xuanjin Du, C N Wang, Liu, Jialu, Yu, Minghui, Haixin Ju, Shanshan Xue, Li, Yaxin, Liu, Jiaojiao, Rufeng Dai, Chen, Jing et al. · 2024 · Figshare
  19. Loss of minichromosome maintenance 4 leads to early renal dysplasia and cystogenesis outcomes
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  20. Worldwide Burden of Urogenital Congenital Anomalies Across Childhood and Adolescence, 1990–2021: Results From the Global Burden of Disease Study 2021
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  21. Bilateral ovarian fibromas with duplex collecting system and ectopic ureter in an 11-year-old girl: a case report with genetic analysis
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  22. Exome Reanalysis Identifies Novel Candidate Genes Associated with Congenital Anomalies of the Kidney and Urinary Tract in China
    Huaping Sun, C N Wang, Wentao Zhang, Mingji Deng, Qian Shen, Jianhua Mao, Qing Sun, Huimin Luo, Huijun Shen, Jingjing Wang et al. · 2026 · medRxiv
  23. Maternal and fetal determinants influencing the occurrence of congenital abnormalities of the kidney and urinary tract: a nested case–control study
    Weizhen Bu, xiaohua LI, yan Xuan, xiaojing Hu, Zhenli Zhao · 2026 · Research Square
  24. Temporal trends and projections in the global burden of congenital genitourinary anomalies from 1990 to 2021: A cross-sectional study
    Siyang Xu, Hua Zhu, Bing Zheng, Bing Zheng, Wen Zhang · 2026 · Journal of International Medical Research
  25. Dose-Dependent and Non-Autonomous Signaling in CAKUT: A Lineage-Specific Framework from Conditional Knockout Studies
    Nela Kelam, Petar Todorović, Patricija Bajt, Nikola Pavlović, Tomislav Rakić, Katarina Vukojević, Anita Racetin · 2026 · Biomolecules
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    Marie Alice Dupont · 2019 · theses.fr (ABES)
  27. Identification and characterisation of loss of function mutations in KIF14 leading to syndromic renal hypodysplasia
    Madeline Louise Reilly · 2018 · theses.fr (ABES)
  28. Role of Tshz3 in the development and function of the kidney
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  30. Application de la biologie des systèmes pour l'identification de marqueurs moléculaires des maladies rénales dans les fluides biologiques
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  31. Identification and implication of novel genes in the pathogenesis of congenital abnormalities of the kidney and urinary tract
    Lara De Tomasi · 2018
  32. Translational strategies to uncover the etiology of congenital anomalies of the kidney and urinary tract
    on behalf of the ArtDECO consortium, Genetica Groep Van Tintelen, Genetica, Child Health, Genetica Sectie Research, Genetica Klinische Genetica, Cancer, Nefrologie, MS Verloskunde, Circulatory Health et al. · 2025 · Utrecht University Repository (Utrecht University)
  33. L'analyse protéomique du liquide amniotique : une clé pour améliorer la compréhension des mécanismes du développement rénal et des maladies associées
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  38. Clinical and Molecular characteristics of kidney and urinary tract congenital anomalies in a cohort of Egyptian patients using whole-exome sequencing
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  41. Excessive maternal methionine intake increases the incidence of congenital anomalies of the kidney and urinary tract in offspring mice
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  42. Silymarin mitigates tartrazine-induced fetal nephrotoxicity and oxidative stress following gestational exposure in rats
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  44. Transcript- and Protein-Level Preservation and Spatial Reorganization of EMT and Vascular–Mesenchymal Gene Programs (SNAI1, TGFB1, PECAM1, VIM) in Human Fetal Kidneys with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
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  45. Environmental risk factors across the phenotypic spectrum of CAKUT
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  46. BindingDB Entry 50017641: Discovery of indol-6-yl-pyrrolo[2,3-c]pyridin-7-one derivatives as bromodomain-containing protein 4 (BRD4) inhibitors for the treatment of kidney fibrosis.
    BindingDB · 2023 · UC San Diego