RNA targets of wild-type and mutant FET family proteins

Hoell, Jessica I, Larsson, Erik, Runge, Simon, Nusbaum, Jeffrey D, Duggimpudi, Sujitha, Farazi, Thalia A, Hafner, Markus, Borkhardt, Arndt +2 more·2011·Nature Structural & Molecular Biology

Cited by (352)

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    Nicolai von Kügelgen, Katarzyna Anna Ludwik, Samantha Mendonsa, Christine Römer, Erik Becher, Laura Breimann, Mara Strauch, Tommaso Mari, Sandrine Mongellaz, Binyamin Zuckerman et al. · 2025 · NAR Molecular Medicine
  2. Alternative 3′ UTRs and RNA-binding proteins Ewsr1b, HuR, and Syncrip organize sequential waves of translation to drive embryonic development
    Keisuke Sato, Ludivine Fierro, Anyu Suginishi, Takahiro Sanada, Tomoya Kotani · 2026 · Cell Reports
  3. Mechanisms of Dendrite Degeneration in Amyotrophic Lateral Sclerosis
    Sebum Lee, Yulei Shang, Eric Jinsheng Huang · 2016 · Springer eBooks
  4. Identification of Essential Components of RNA Binding Domain of TLS/FUS
    Naomi Ueda, Ryoma Yoneda, Riki Kurokawa · 2024 · Biomedical Sciences
  5. Molecular Basis of DNA Repair Defects in FUS-Associated ALS: Implications of a New Paradigm and Its Potential as Therapeutic Target
    Haibo Wang, Muralidhar L. Hegde · 2020 · IntechOpen eBooks
  6. Big data analytics in bioinformatics
    Gronning Alexander (Gulliver Bjørnholt) · 2020
  7. FUS binding to RNA prevents R-loops
    Valery F. Thompson, Daniel R. Wieland, Vivian Mendoza-Leon, Helen I. Janis, Michelle A. Lay, Lucas M. Harrell, Jacob C. Schwartz · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Complexity of familial amyotrophic lateral sclerosis
    Marka van Blitterswijk · 2012 · Utrecht University Repository (Utrecht University)
  9. Transcriptome wide characterization of target sites and alternative splicing regulation mediated by RBM10
    Yongbo Wang · 2013 · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
  10. Cross-Sectional Survey of Relevant Literatures as to the Current Proposed Disease Mechanisms and Treatments of Amyotrophic Lateral Sclerosis (ALS)
    Zachary Sanford · 2015 · Marshall Journal of Medicine
  11. Molecular analysis of the FET family fusion oncoprotein FUS-DDIT3
    Christer Thomsen · 2012 · Gothenburg University Publications Electronic Archive (Gothenburg University)
  12. METHOD Open Access
    Lasse Maretty, Jonas A. Sibbesen, Anders Krogh · 2014
  13. MicroRNA regulation by the DNA and RNA binding proteins EWS and FUS
    Ana Miguel Fernandes · 2012 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
  14. Modelling C9orf72-linked frontotemporal dementia and amyotrophic lateral sclerosis
    Sarah Ryan · 2015 · Research Explorer (The University of Manchester)
  15. A survey of axonal transport function and motor behaviour in Drosophila models of amyotrophic lateral sclerosis
    Katie R. Baldwin · 2015 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
  16. Study of the multifunctional nuclear scaffold protein. A kinase anchoring protein 95
    Graciela López-Soop · 2017 · NORA - Norwegian Open Research Archives
  17. SURVEY AND SUMMARY Design and bioinformatics analysis of genome-wide CLIP experiments
    Tao Wang, Guanghua Xiao, Yongjun Chu, Michael Q. Zhang, David R. Corey, Yang Xie · 2014
  18. Fusion and Wildtype Proteins of EWSR1 Interact in a Protein Granule
    Nasiha S. Ahmed · 2020 · UA Campus Repository (The University of Arizona)
  19. HnRNP G Reduces Neuron Death in Amyotrophic Lateral Sclerosis by Preventing Abnormal TDP-43 Accumulation
    Fang Yang, Wenzhi Chen, Yu Zhu, Pei He, Shishi Jiang, Renshi Xu · 2021 · Research Square
  20. Dietary Polyphenols and Neuroprotection
    Rui F. M. Silva, Lea Pogačnik · 2022 · MDPI eBooks
  21. The patient's own bone marrow-derived stromal cells
    Hans de Munter · 2021
  22. Peer Review #1 of "The PARA-suite: PAR-CLIP specific sequence read simulation and processing (v0.2)"
    2016 · PeerJ
  23. Peer Review #1 of "The PARA-suite: PAR-CLIP specific sequence read simulation and processing (v0.1)"
    2016 · PeerJ
  24. Peer Review #2 of "The PARA-suite: PAR-CLIP specific sequence read simulation and processing (v0.1)"
    2016 · PeerJ
  25. HnRNP G Reduces Neuron Death in Amyotrophic Lateral Sclerosis by Preventing Abnormal TDP-43 Accumulation
    Fang Yang, Wenzhi Chen, Yu Zhu, Shishi Jiang, Xiaohua Wang, Renshi Xu · 2021 · Research Square
  26. RNA Dysfunction and RNA binding Proteins in the Syndrome of ALS/FTD
    2013 · Journal of Syndromes
  27. Molecular determinants of Karyopherin-β2 chaperone and disaggregation activity
    Charlotte M. Fare, Kevin Rhine, Andrew Lam, Sua Myong, James Shorter · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  28. RNA and FUS act in concert to prevent TDP-43 spatial segregation
    Clément Demongin, S. Tranier, Vandana Joshi, Léa Ceschi, Bénédicte Desforges, David Pastré, Loïc Hamon · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  29. FUS Aggregation by Shear Stress on Pipetting and Its Suppression by Non-coding RNA
    Masato Katahira · 2023 · Springer eBooks
  30. Functional Properties of Phase Separation and Intranuclear Complex of FUS in the Pathogenesis of ALS/FTLD
    Shinsuke Ishigaki · 2023 · Springer eBooks
  31. Roles of SNORD115 and SNORD116 ncRNA clusters in neuronal differentiation
    Aleksandra Helwak, Tomasz W. Turowski, Christos Spanos, David W. Tollervey · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Additional file 1 of CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
    Kai Han, Feng‐Wei Wang, Chenhui Cao, Ling Han, Jiewei Chen, Rixin Chen, Zihao Feng, Jie Luo, Xiaohan Jin, Jin‐Ling Duan et al. · 2020 · Figshare
  33. Additional file 5 of CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
    Kai Han, Feng‐Wei Wang, Chenhui Cao, Ling Han, Jiewei Chen, Rixin Chen, Zihao Feng, Luo, Jie, Xiaohan Jin, Jin‐Ling Duan et al. · 2020 · Figshare
  34. FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability
    Celeste Giansanti, Jack C. Schultz, Jessica Rose Jackson, Alessandro Vindigni, David Cortez · 2026 · Nature Communications
  35. Additional file 2 of CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
    Han, Kai, Wang, Feng-Wei, Cao, Chen-Hui, Ling, Han, Chen, Jie-Wei, Chen, Ri-Xin, Feng, Zi-Hao, Luo, Jie, Jin, Xiao-Han, Jinling Duan et al. · 2020 · Figshare
  36. Additional file 6 of CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
    Han, Kai, Wang, Feng-Wei, Cao, Chen-Hui, Ling, Han, Chen, Jie-Wei, Chen, Ri-Xin, Feng, Zi-Hao, Luo, Jie, Jin, Xiao-Han, Duan, Jin-Ling et al. · 2020 · Figshare
  37. Additional file 3 of CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
    Han, Kai, Wang, Feng-Wei, Cao, Chen-Hui, Ling, Han, Chen, Jie-Wei, Chen, Ri-Xin, Feng, Zi-Hao, Luo, Jie, Jin, Xiao-Han, Jinling Duan et al. · 2020 · Figshare
  38. Additional file 1 of Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration
    Zhao, Beibei, Catherine M. Cowan, Juliane A. Coutts, Darren Christy, Ananya Saraph, Shawn C. C. Hsueh, Stephen S. Plotkin, I. R. A. Mackenzie, Johanne M Kaplan, Neil R. Cashman · 2024 · Figshare
  39. Additional file 4 of CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
    Han, Kai, Wang, Feng-Wei, Cao, Chen-Hui, Ling, Han, Chen, Jie-Wei, Chen, Ri-Xin, Feng, Zi-Hao, Luo, Jie, Jin, Xiao-Han, Jinling Duan et al. · 2020 · Figshare
  40. Additional file 1 of A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics
    Gaël Nicolas, Myriam Sévigny, François Lecoquierre, Marguet, Florent, Andréanne Deschênes, del Pelaez, Maria Carment, Sébastien Feuillette, Anaïs Audebrand, Magalie Lecourtois, Stéphane Rousseau et al. · 2022 · Figshare
  41. Conditional truncation of the FUS protein in mice : a new animal model of the ALS/FTD continuum
    Jelena Scekic‐Zahirovic · 2016 · theses.fr (ABES)
  42. Implication des macrophages périphériques dans la Sclérose latérale Amyotrophique
    Aude Chiot · 2018 · theses.fr (ABES)
  43. Novel FUS and CHCHD10 models to investigate pathogenic mechanisms in Amyotrophic Lateral Sclerosis
    Annis-Rayan Bourefis · 2019 · theses.fr (ABES)
  44. The link between PARP1-mediated signaling and RNA-binding protein FUS in response to DNA damage
    Anastasiya Singatulina · 2019
  45. Étude de la composante neuroinflammatoire dans les DFT/SLA
    Julie Smeyers · 2020 · theses.fr (ABES)
  46. Structural and functional insights into YB-1 and Lin28 interplay in mRNA regulation
    Anastasiia Samsonova · 2020
  47. An ALS subtype–specific SNRNP70 exon-8 splicing alteration is associated with ubiquitin–proteasome pathway signatures
    Tadashi Nakaya · 2026 · Gene Reports
  48. Rational Design of a Multivalent RNA Combining Structural Motifs Tailored to Multiple Domains of Fused in Sarcoma for Potent Inhibition of Aggregation
    Nobuaki Kuroiwa, Fumika Sakaue, Motoki Miura, Ayano Go, Ryo Iwase, Hiroya Kuwahara, Nobuo Sanjo, Kumiko Ui‐Tei, Takanori Yokota · 2026 · ChemBioChem
  49. Physiological and pathological functions of TAF15 in neurodegenerative diseases and cancers
    Congcong Liu, Lanxia Meng, Zhentao Zhang · 2026 · Journal of Advanced Research
  50. Electron Microscopy Identifies Protein Conformational Substates in Liquid Environment
    Xiaozhe Dong, Hong Zhang, Zhi Qu, Sicheng Zhao, Li J, Yihao Niu, Xiaoyun Pang, Qian Huang, Y R Kim, Oh‐Hoon Kwon et al. · 2026 · ACS Nano
  51. N6-Methyladenosine RNA Modifications Influence the Stability of FUS-Dependent Biological Condensate Formation
    Chamali Thalagaha Mudiyanselage, Milan Pandey, Sudeshi M. Abedeera, Chathurani Ekanayake, Aftab Mollah, Nadia Anwaar, Arkaprabha Konar, Sanjaya C. Abeysirigunawardena · 2026 · ACS Bio & Med Chem Au
  52. EWSR1 associates with the 40S ribosomal subunit and represses translation to maintain endoplasmic reticulum homeostasis
    Zahrat El Oula Hassoun, Loïc Ongena, Lionel Condé, Bartimée Galvan, Grégory Fettweis, Michelle Lion, Romuald Soin, Jonathan Bruyr, Florence Lemaitre, Marc Thiry et al. · 2026 · Nucleic Acids Research