The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Insights into SARS-CoV transcription and replication from the structure of the nsp7–nsp8 hexadecamer
Open accessAbstract
Coronavirus replication and transcription machinery involves multiple virus-encoded nonstructural proteins (nsp). We report the crystal structure of the hexadecameric nsp7–nsp8 supercomplex from the severe acute respiratory syndrome coronavirus at 2.4-Å resolution. nsp8 has a novel 'golf-club' fold with two conformations. The supercomplex is a unique hollow, cylinder-like structure assembled from eight copies of nsp8 and held tightly together by eight copies of nsp7. With an internal diameter of ∼30 Å, the central channel has dimensions and positive electrostatic properties favorable for nucleic acid binding, implying that its role is to confer processivity on RNA-dependent RNA polymerase.
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PROCHECK: a program to check the stereochemical quality of protein structures
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Identification of a novel coronavirus in patients with severe acute respiratory syndrome
Drosten, C., Günther, S., Preiser, W., van der Werf, S., Brodt, H.-R., Becker, S., Rabenau, H., Panning, M., Kolesnikova, L., Fouchier, R. A. M., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030747 · Cited by 4,574
Intrinsic Disorder and Protein Function
Dunker, A. K., Brown, C. J., Lawson, J. D., Iakoucheva, L. M., & Obradović, Z. (2002) · Biochemistry · doi:10.1021/bi012159+ · Cited by 1,731
Cited by
Coronaviruses post-SARS: update on replication and pathogenesis
Perlman, S., & Netland, J. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2147 · Cited by 1,764
The Molecular Biology of Coronaviruses
Masters, P. S. (2006) · Advances in Virus Research · doi:10.1016/s0065-3527(06)66005-3 · Cited by 1,761
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
Yin, W., Mao, C., Luan, X., Shen, D.-D., Shen, Q., Su, H., Wang, X., Zhou, F., Zhao, W., Gao, M., et al. (2020) · Science · doi:10.1126/science.abc1560 · Cited by 1,219
Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection
Cheng, V. C. C., Lau, S. K. P., Woo, P. C. Y., & Yuen, K. Y. (2007) · Clinical Microbiology Reviews · doi:10.1128/cmr.00023-07 · Cited by 1,192
te Velthuis, A. J. W., van den Worm, S. H. E., Sims, A. C., Baric, R. S., Snijder, E. J., & van Hemert, M. J. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001176 · Cited by 893
Metadata
- Authors
- Zhai, Y., Sun, F., Li, X., Pang, H., Xu, X., Bartlam, M., & Rao, Z.
- Venue
- Nature Structural & Molecular Biology
- Published
- 2005-10-16
- Volume
- 12
- Issue
- 11
- Pages
- 980-986
- ISSN
- 1545-9985 (ISSN-L)
- 1545-9993
- OpenAlex
- W2134092129
- Cited by
- 290
- References
- 3
- FWCI
- 10.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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