The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Parkin as a tumor suppressor gene for hepatocellular carcinoma
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Citations
Cites
Genetic instabilities in human cancers
Lengauer, C., Kinzler, K. W., & Vogelstein, B. (1998) · Nature · doi:10.1038/25292 · Cited by 4,168 · cited 1×
“Human cancer develops through a multistep process involving the accumulation of genetic alterations that drive the progression of normal cells into malignant derivatives (Lengauer et al., 1998).”
BackgroundFamilial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
Shimura, H., Hattori, N., Kubo, S.-I., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K., et al. (2000) · Nature Genetics · doi:10.1038/77060 · Cited by 2,024 · cited 1×
“There are an increasing number of studies, including ours, showing that parkin is an E3 ubiquitin ligase that targets a variety of candidate substrate proteins, resulting in proteosomal degradation (Jackson et al., 2000; Shimura et al., 2000; Takahashi et al., 2003).”
BackgroundSelf-citationRules for Making Human Tumor Cells
Hahn, W. C., & Weinberg, R. A. (2002) · New England Journal of Medicine · doi:10.1056/nejmra021902 · Cited by 951
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons
Goldberg, M. S., Fleming, S. M., Palacino, J. J., Cepeda, C., Lam, H. A., Bhatnagar, A., Meloni, E. G., Wu, N., Ackerson, L. C., Klapstein, G. J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308947200 · Cited by 913
Parkin-deficient mice are not a robust model of parkinsonism
Perez, F. A., & Palmiter, R. D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409598102 · Cited by 477
Cited by
Mitochondrial Dysfunction in Cancer
Boland, M. L., Chourasia, A. H., & Macleod, K. F. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2013.00292 · Cited by 489
Ubiquitin ligases in oncogenic transformation and cancer therapy
Senft, D., Qi, J., & Ronai, Z. A. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.105 · Cited by 489
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
Zhang, C., Lin, M., Wu, R., Wang, X., Yang, B., Levine, A. J., Hu, W., & Feng, Z. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113884108 · Cited by 431
Chourasia, A. H., Boland, M. L., & Macleod, K. F. (2015) · Cancer & Metabolism · doi:10.1186/s40170-015-0130-8 · Cited by 270
Role of tumor and host autophagy in cancer metabolism
Poillet-Perez, L., & White, E. (2019) · Genes & Development · doi:10.1101/gad.325514.119 · Cited by 266
Metadata
- Authors
- Fujiwara, M., Marusawa, H., Wang, H.-Q., Iwai, A., Ikeuchi, K., Imai, Y., Kataoka, A., Nukina, N., Takahashi, R., & Chiba, T.
- Venue
- Oncogene
- Published
- 2008-06-23
- Volume
- 27
- Issue
- 46
- Pages
- 6002-6011
- ISSN
- 0950-9232 (ISSN-L)
- 1476-5594
- OpenAlex
- W2071133957
- Cited by
- 218
- References
- 5
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- green
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- This page
- CoChat. (2026). Citation check: Parkin as a tumor suppressor gene for hepatocellular carcinoma. https://app.cochat.ai/papers/10.1038/onc.2008.199
- The paper
- Fujiwara, M., Marusawa, H., Wang, H.-Q., Iwai, A., Ikeuchi, K., Imai, Y., Kataoka, A., Nukina, N., Takahashi, R., & Chiba, T. (2008). Parkin as a tumor suppressor gene for hepatocellular carcinoma. Oncogene. https://doi.org/10.1038/onc.2008.199
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
