The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy
Open accessAbstract
The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has been attributed to the virally-encoded oncoprotein, Tax. Unlike the v-onc proteins encoded by other oncogenic animal retroviruses that transform cells, Tax does not originate from a c-onc counterpart. In this article, we review progress in our understanding of HTLV-1 infectivity, cellular transformation, anti-sense transcription and therapy, 30 years after the original discovery of this virus.
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Cites
Poiesz, B. J., Ruscetti, F. W., Gazdar, A. F., Bunn, P. A., Minna, J. D., & Gallo, R. C. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7415 · Cited by 5,043 · cited 3×
“It was isolated in 1980 in the United States (Poiesz et al., 1980) and then in Japan (Yoshida et al.”
Creation of human tumour cells with defined genetic elements
Hahn, W. C., Counter, C. M., Lundberg, A. S., Beijersbergen, R. L., Brooks, M. W., & Weinberg, R. A. (1999) · Nature · doi:10.1038/22780 · Cited by 2,345
Yoshida, M., Miyoshi, I., & Hinuma, Y. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.6.2031 · Cited by 2,169
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation
Matsuoka, M., & Jeang, K.-T. (2007) · Nature Reviews Cancer · doi:10.1038/nrc2111 · Cited by 829
Self-citationRas Proteins Induce Senescence by Altering the Intracellular Levels of Reactive Oxygen Species
Lee, A. C., Fenster, B. E., Ito, H., Takeda, K., Bae, N. S., Hirai, T., Yu, Z.-X., Ferrans, V. J., Howard, B. H., & Finkel, T. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.7936 · Cited by 691 · cited 2×
“Oncogene species is consistent with similar reactive oxygen speciesinduction by other viral transforming proteins, such as Ras (Lee et al., 1999), c-Myc (Vafa et al., 2002) and Epstein-Barr virus EBNA-1 protein (Gruhne et al., 2009).”
Pais-Correia, A.-M., Sachse, M., Guadagnini, S., Robbiati, V., Lasserre, R., Gessain, A., Gout, O., Alcover, A., & Thoulouze, M.-I. (2010) · Nature Medicine · doi:10.1038/nm.2065 · Cited by 344
Cell-free HTLV-1 infects dendritic cells leading to transmission and transformation of CD4+ T cells
Jones, K. S., Petrow-Sadowski, C., Huang, Y. K., Bertolette, D. C., & Ruscetti, F. W. (2008) · Nature Medicine · doi:10.1038/nm1745 · Cited by 284
Saito, M., Matsuzaki, T., Satou, Y., Yasunaga, J.-I., Saito, K., Arimura, K., Matsuoka, M., & Ohara, Y. (2009) · Retrovirology · doi:10.1186/1742-4690-6-19 · Cited by 184
Self-citationWatanabe, M. (2005) · Blood · doi:10.1182/blood-2004-09-3646 · Cited by 129 · cited 1×
“NF-kB inhibitors also effectively induce apoptosis of ATL cells as NF-kB is highly activated in ATL cells (Dewan et al., 2003; Watanabe et al., 2005).”
Taylor, G. P., Goon, P., Furukawa, Y., Green, H., Barfield, A., Mosley, A., Nose, H., Babiker, A., Rudge, P., Usuku, K., et al. (2006) · Retrovirology · doi:10.1186/1742-4690-3-63 · Cited by 117
Cited by
HTLV Tax: A Fascinating Multifunctional Co-Regulator of Viral and Cellular Pathways
Currer, R., Van Duyne, R., Jaworski, E., Guendel, I., Sampey, G., Das, R., Narayanan, A., & Kashanchi, F. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00406 · Cited by 156
Ruggero, K., Guffanti, A., Corradin, A., Sharma, V. K., De Bellis, G., Corti, G., Grassi, A., Zanovello, P., Bronte, V., Ciminale, V., et al. (2014) · Journal of Virology · doi:10.1128/jvi.02823-13 · Cited by 139
Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP
Enose-Akahata, Y., Vellucci, A., & Jacobson, S. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02563 · Cited by 88
Gazon, H., Lemasson, I., Polakowski, N., Césaire, R., Matsuoka, M., Barbeau, B., Mesnard, J.-M., & Peloponese, J.-M. (2012) · Journal of Virology · doi:10.1128/jvi.00661-12 · Cited by 73
Self-citationAn animal model of adult T-cell leukemia: humanized mice with HTLV-1–specific immunity
Tezuka, K., Xun, R., Tei, M., Ueno, T., Tanaka, M., Takenouchi, N., & Fujisawa, J.-I. (2014) · Blood · doi:10.1182/blood-2013-06-508861 · Cited by 68
Metadata
- Authors
- Matsuoka, M., & Jeang, K.-T.
- Venue
- Oncogene
- Published
- 2010-11-29
- Volume
- 30
- Issue
- 12
- Pages
- 1379-1389
- ISSN
- 0950-9232 (ISSN-L)
- 1476-5594
- OpenAlex
- W2085746138
- Cited by
- 268
- References
- 12
- FWCI
- 8.55
- Type
- journal article
- Language
- en
- Open access
- green
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