The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
Future prospects of immune checkpoint blockade in cancer: from response prediction to overcoming resistance
Open accessAbstract
Recent advances in the understating of tumor immunology suggest that cancer immunotherapy is an effective treatment against various types of cancer. In particular, the remarkable successes of immune checkpoint-blocking antibodies in clinical settings have encouraged researchers to focus on developing other various immunologic strategies to combat cancer. However, such immunotherapies still face difficulties in controlling malignancy in many patients due to the heterogeneity of both tumors and individual patients. Here, we discuss how tumor-intrinsic cues, tumor environmental metabolites, and host-derived immune cells might impact the efficacy and resistance often seen during immune checkpoint blockade treatment. Furthermore, we introduce biomarkers identified from human and mouse models that predict clinical benefits for immune checkpoint blockers in cancer.
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Cites
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Maibach, F., Sadozai, H., Seyed Jafari, S. M., Hunger, R. E., & Schenk, M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02105 · Cited by 312
High-dose vitamin C enhances cancer immunotherapy
Magrì, A., Germano, G., Lorenzato, A., Lamba, S., Chilà, R., Montone, M., Amodio, V., Ceruti, T., Sassi, F., Arena, S., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay8707 · Cited by 285
iRGD Peptide as a Tumor-Penetrating Enhancer for Tumor-Targeted Drug Delivery
Kang, S., Lee, S., & Park, S. (2020) · Polymers · doi:10.3390/polym12091906 · Cited by 139
Combination of Immunotherapy With Targeted Therapy: Theory and Practice in Metastatic Melanoma
Yu, C., Liu, X., Yang, J., Zhang, M., Jin, H., Ma, X., & Shi, H. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00990 · Cited by 126
Metadata
- Authors
- Park, Y.-J., Kuen, D.-S., & Chung, Y.
- Venue
- Experimental & Molecular Medicine
- Published
- 2018-08
- Volume
- 50
- Issue
- 8
- Pages
- 1-13
- ISSN
- 1226-3613 (ISSN-L)
- 2092-6413
- OpenAlex
- W2888038493
- Cited by
- 194
- References
- 57
- FWCI
- 10.20
- Type
- journal article
- Language
- en
- Open access
- gold
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- Park, Y.-J., Kuen, D.-S., & Chung, Y. (2018). Future prospects of immune checkpoint blockade in cancer: from response prediction to overcoming resistance. Experimental & Molecular Medicine. https://doi.org/10.1038/s12276-018-0130-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
