Role of AID in the temporal pattern of acquisition of driver mutations in multiple myeloma
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Different patients might experience different exposure in time and intensity in the germinal center, potentially reflecting unique interaction with the external environment.
“Importantly, based on the different number of GC mutations observed across hundreds of WGS, it has been shown that different patients might experience different exposure in time and intensity, potentially reflecting unique interaction with the external environment.12,13,15,72,73”
From Evolution of Multiple Myeloma from a Genomic Perspective (2026) · cites this paper as [72]
Non-synonymous mutations in oncogenes mediated by AID can also be acquired before HY.
“Additionally, non-synonymous mutations in oncogene mediated by AID can also be acquired before HY.72”
From Evolution of Multiple Myeloma from a Genomic Perspective (2026) · cites this paper as [72]
Cites
Genomic classification and prognosis in acute myeloid leukemia
Papaemmanuil, E., Gerstung, M., Bullinger, L., Gaidzik, V. I., Paschka, P., Roberts, N. D., Potter, N. E., Heuser, M., Thol, F., Bolli, N., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1516192 · Cited by 4,350 · see citing works
Self-citationChapuy, B., Stewart, C., Dunford, A. J., Kim, J., Kamburov, A., Redd, R. A., Lawrence, M. S., Roemer, M. G. M., Li, A. J., Ziepert, M., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0016-8 · Cited by 1,941 · see citing works
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Evolution of Multiple Myeloma from a Genomic Perspective
Maura, F., Samur, M., & Munshi, N. (2026) · Blood · doi:10.1182/blood.2024026313 · Cited by 8 · see citing works
Self-citation
- Authors
- Maura, F., Rustad, E. H., Yellapantula, V., Łuksza, M., Hoyos, D., Maclachlan, K. H., Diamond, B. T., Greenbaum, B. D., Morgan, G., Lesokhin, A., Papaemmanuil, E., & Landgren, O.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- Tisch Cancer Institute (US)
- NYU Langone Health (US)
- Corresponding author
- Maura, Francesco
- ORCID
- Venue
- Leukemia
- Published
- 2019-12-13
- Volume
- 34
- Issue
- 5
- Pages
- 1476-1480
- ISSN
- 0887-6924 (ISSN-L)
- 1476-5551
- OpenAlex
- W2995424845
- Cited by
- 50
- References
- 2
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 7 · 2023: 9 · 2022: 6 · 2021: 12 · 2020: 10 · 2019: 1
- FWCI
- 5.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Leukemia (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Health & Human Services | NIH | National Cancer Institute (P30 CA 008748)
- Topics
- Health Sciences › Medicine › Hematology › Multiple Myeloma Research and Treatments
- Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer Genomics and Diagnostics
- Keywords
- driver mutations, multiple myeloma, somatic mutations, clonal evolution
- MeSH terms
- Whole Genome Sequencing, AICDA (Activation-Induced Cytidine Deaminase), Cytidine Deaminase, DNA Mutational Analysis, Humans, Multiple Myeloma, Mutation, Biomarkers, Tumor, Clonal Evolution
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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