Protein neddylation and its role in health and diseases

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40. Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis
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42. Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1
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61. The FBXW2–MSX2–SOX2 axis regulates stem cell property and drug resistance of cancer cells
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62. Targeting epigenetic regulatory machinery to overcome cancer therapy resistance
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76. Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer
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77. Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics
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79. AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness
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80. Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling
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81. APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain
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82. A natural product-like inhibitor of NEDD8-activating enzyme
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83. Suppression of tumor angiogenesis by targeting the protein neddylation pathway
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84. Deregulated neddylation in liver fibrosis
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85. Regulation of parkin and PINK1 by neddylation
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86. SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1α ubiquitination and degradation
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87. Neddylation pathway is up-regulated in human intrahepatic cholangiocarcinoma and serves as a potential therapeutic target
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88. Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum
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89. Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia
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90. Neddylation dysfunction in Alzheimer's disease
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91. Cullin-RING Ligase 5: Functional characterization and its role in human cancers
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92. MLN4924, an NAE inhibitor, suppresses AKT and mTOR signaling via upregulation of REDD1 in human myeloma cells
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95. Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells
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96. Neddylation plays an important role in the regulation of murine and human dendritic cell function
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153. Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity
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