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Aldosterone is a possible new stimulating factor for promoting vascular calcification

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M2 macrophage-derived extracellular vesicles protect against abdominal aortic aneurysm by modulating macrophage polarization through miR221-5p

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Anti-fibrotic effect of 6-bromo-indirubin-3′-oxime (6-BIO) via regulation of activator protein-1 (AP-1) and specificity protein-1 (SP-1) transcription factors in kidney cells

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Investigation of the Potential Mechanism of Danggui Shaoyao San for the Treatment of Non-alcoholic Fatty Liver Disease (NAFLD) with Network Pharmacology and Molecular Docking

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Network Pharmacology and Molecular Docking Study on the Multi-Target Mechanisms of Aloe vera for Non-Alcoholic Steatohepatitis Treatment

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Sinomenine Ameliorates Liver Fibrosis by Blocking TGF ‐β/ SMAD and c‐ JUN Signaling

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Comprehensive molecular characterization of circRNA-associated ceRNA network in constrictive pericarditis

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Sanye tablet regulates gut microbiota and bile acid metabolism to attenuate hepatic steatosis

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MicroRNA-137-3p Improves Nonalcoholic Fatty Liver Disease through Activating AMPKα

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RORα regulates hepatic lipolysis by inducing transcriptional expression of PNPLA3 in mice

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Sensitive and Deep Coverage Phosphoproteome Detection Method Reveals Spleen as a More Sensitive Organ than Liver in Early Detection of Liver Fibrosis-Related Signaling Protein Dysregulation

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Multiomics Analysis and Machine Learning-based Identification of Molecular Signatures for Diagnostic Classification in Liver Disease Types Along the Microbiota-gut-liver Axis

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Ameliorative effects of sildenafil against carbon tetrachloride induced hepatic fibrosis in rat model through downregulation of osteopontin gene expression

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Ursolic acid: A promising therapeutic agent for metabolic dysfunction-associated steatotic liver disease via inhibition of SPP1-induced Th17 cell differentiation: Editorial on “Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against metabolic dysfunction-associated steatotic liver disease”

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SOX9: a key transcriptional regulator in organ fibrosis

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The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8

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γδ T cell-stromal networks modulate matrix composition and vascularity in foreign body response

Ruta, A., Krishnan, K., Woo, J., Mejías, J. C., Gray-Gaillard, E. F., Maestas, D. R., Nguyen, H. H., Rindone, A. N., Cherry, C., Patatanian, M., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71540-7 · Cited by 5 · see citing works

Multi-omics analysis reveals distinct gene regulatory mechanisms between primary and organoid-derived human hepatocytes

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Functional interaction between macrophages and hepatocytes dictate the outcome of liver fibrosis

Xie, M., Chia, R. H., Li, D., Teo, F. X., Krueger, C., & Sabapathy, K. (2021) · Life Science Alliance · doi:10.26508/lsa.202000803 · Cited by 5 · see citing works

TGF-β2 Regulates Transcription of the K+/Cl− Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

Rigkou, A., Magyar, A., Speer, J. M., & Roussa, E. (2022) · Cells · doi:10.3390/cells11233861 · Cited by 5 · see citing works

Transcriptomic Analysis of Newborn Hanwoo Calves: Effects of Maternal Overnutrition during Mid- to Late Pregnancy on Subcutaneous Adipose Tissue and Liver

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A single-cell gene regulatory network inference method for identifying complex regulatory dynamics across cell phenotypesPreprint

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Molecular mechanisms of lncRNA NEAT1 in the pathogenesis of liver-related diseases, with special focus on therapeutic approaches

Wang, Y., Sanghvi, G. V., Ballal, S., Sharma, R., Pathak, P. K., Shankhyan, A., Sun, J., Chen, Q., Ma, Y., Huang, L., et al. (2025) · Pathology - Research and Practice · doi:10.1016/j.prp.2025.155867 · Cited by 4 · see citing works

Hepatocyte-Specific Casein Kinase 1 Epsilon Ablation Ameliorates Metabolic Dysfunction–Associated Steatohepatitis by Up-Regulating Tumor Necrosis Factor Receptor–Associated Factor 3 in Mice

Leya, M., Jeong, H., Yang, D., Bao, T. H. T. N., Pandeya, P. R., Oh, S.-I., Roh, Y., Kim, J.-W., & Kim, B. (2024) · American Journal Of Pathology · doi:10.1016/j.ajpath.2024.08.003 · Cited by 4 · see citing works

Identification of biomarkers associated with coronary artery disease and non-alcoholic fatty liver disease by bioinformatics analysis and machine learning

Lu, C., Han, M., Ma, Q., Li, Y., & Zhang, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-87923-7 · Cited by 4 · see citing works

Expression of immune related genes and possible regulatory mechanisms in different stages of non-alcoholic fatty liver disease

He, R., Guan, C., Zhao, X.-D., Yu, L., & Cui, Y.-F. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1364442 · Cited by 5 · see citing works

Super-enhancer signature reveals key mechanisms associated with resistance to non-alcoholic steatohepatitis in humans with obesityPreprint

Hung, Y.-H., Sritharan, R., Vohl, M., Ilkayeva, O., Biertho, L. D., Tchernof, A., White, P. J., & Sethupathy, P. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.20.457162 · Cited by 4 · see citing works

β-Resorcylic acid prevents MASLD in ob/ob mice by modulating lipid metabolism and inflammation in the liver

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Kindlin-2 maintains liver homeostasis by regulating GSTP1–OPN-mediated oxidative stress and inflammation in mice

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Identification of IL-34 and Slc7al as potential key regulators in MASLD progression through epigenomic profiling

Zeng, C., Wei, M., Li, H., Yu, L., Wang, C., Mu, Z., Huang, Z., Ke, Y., Li, L., Xiao, Y., et al. (2025) · Epigenomics · doi:10.1080/17501911.2025.2467028 · Cited by 2 · see citing works

Molecular mechanisms from the transition of MASLD-MASH-liver fibrosis to liver cancer

Zhang, C., Sui, Y., Liu, S., & Yang, M. J. (2025) · The Journal of Precision Medicine Health and Disease · doi:10.1016/j.premed.2025.100012 · Cited by 2 · see citing works

A roadmap to unveil the mechanism(s) of natural indole-derived molecules against NAFLD-derived HCC via systems pharmacology

Oh, K., Kwon, G.-H., Lee, K. J., Eom, J. A., Kim, D. J., & Suk, K. T. (2025) · Translational Oncology · doi:10.1016/j.tranon.2025.102618 · Cited by 2 · see citing works

c-Jun and Fra-2 pair up to Myc-anistically drive HCC

Bakiri, L., & Wagner, E. F. (2024) · Cell Cycle · doi:10.1080/15384101.2024.2429968 · Cited by 2 · see citing works

Osthole Induces Hepatic Stellate Cell Ferroptosis to Alleviate Liver Fibrosis by Inhibiting the Y‐Box Binding Protein 1‐Wnt/β‐Catenin Axis Through Downregulating Myocyte Enhancer Factor 2A

Tong, M., Liu, M., Chen, L., Lin, Y., & Zheng, Q. Y. (2025) · Chemical Biology & Drug Design · doi:10.1111/cbdd.70113 · Cited by 2 · see citing works

Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc (Author copy)Preprint

Bakiri, L. (2024) · doi:10.22541/au.171403693.35484937/v1 · Cited by 1 · see citing works

MegaMASLD: An interactive platform for exploring stratified transcriptomic signatures in MASLD progressionPreprint

Cheng, H. S., Chua, D., Chan, S. T., Yew, K. C., Wong, H. S., & Tan, N. S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.21.603199 · Cited by 2 · see citing works

Activator protein-1 in liver pathology: from precancerous diseases to hepatocellular carcinoma

Villarruel-Melquiades, F., Aguirre-Maldonado, I., Herrera-López, E. E., Mendoza‐Garrido, M. E., Pérez‐Carreón, J. I., Bañuelos, C., & Camacho, J. (2024) · Hepatoma Research · doi:10.20517/2394-5079.2024.95 · Cited by 1 · see citing works

Identification of scavenger receptor (LmSRA3) gene and its immune response to Aeromonas veronii in Lateolabrax maculatus

Chen, H., Lin, C., Zhang, B., Yan, L. E., Zhang, B., Wang, P., Qiu, L., & Zhao, C. (2025) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2025.105320 · Cited by 1 · see citing works

scNucMap: mapping the nucleosome landscapes at single-cell resolution

Xiang, Q., & Lai, B. (2025) · Bioinformatics · doi:10.1093/bioinformatics/btaf324 · Cited by 1 · see citing works

Unraveling the mechanisms of bisphenol A-Induced lupus nephritis through network toxicology and machine learning approaches

Tang, Z., Li, M., Cheng, L., Chen, J., & Huang, C. (2025) · International Journal of Environmental Health Research · doi:10.1080/09603123.2025.2547853 · Cited by 1 · see citing works

A Generalizable Transformer Framework for Gene Regulatory Network Inference from Single‐Cell Transcriptomes

Weng, G., Kim, H., Martin, P. C. N., Kim, J., Kim, T., Nam, G., Kim, D., & Won, K. J. (2026) · Advanced Intelligent Systems · doi:10.1002/aisy.202500781 · Cited by 1 · see citing works

Overexpression of IGF2 Alters the Transcriptional Profile of Goose Skeletal Muscle Satellite Cells

Wang, C., Liu, Y., Yang, Y., Chen, S., & He, D. (2026) · Biomolecules · doi:10.3390/biom16040565 · Cited by 1 · see citing works

Integrated Bulk and Single‐Cell RNA ‐Seq Analysis Reveals Transcriptional Activation of PTGS2 by FOS in Progression From T2DM to T2DM ‐Associated NAFLD

Lin, R., Xu, L., Zhou, Y., Fan, Y., Xie, H., Li, W., Hu, T., & Liu, C. (2026) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.71182 · Cited by 1 · see citing works

Osteopontin in Atrial Fibrillation and Atrial Remodeling

Mamazhakypov, A., Neupane, B., Шогаибович, С. А., Sydykov, A. S., SCHERMULY, R. T., Gramlich, M., & Pradhan, K. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.125.048418 · Cited by 1 · see citing works

Activated hepatic stellate cell membrane-camouflaged nanomedicine enables targeted HDAC6 inhibition for liver fibrosis therapy

Yu, L., Zhang, L., Gao, L., Huang, S., Qin, X., Wang, Z., Li, S., Mei, C., Zhang, M., Zhang, Y., et al. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.115100 · Cited by 1 · see citing works

Stratifying Non-alcoholic Steatohepatitis With the Non-invasive Ultrasound Markers Shear Wave Dispersion Slope and Shear Wave Velocity: An Animal Study

Kong, W., Tang, Y., Liu, L., Zhang, G., Liu, Y., & Liu, J. (2022) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2022.06.023 · Cited by 1 · see citing works

Identification of biomarkers associated with immune-propionate metabolism in nonalcoholic fatty liver disease

Qu, S., Huang, H. F., Diao, Y., Liu, B., Tang, B., Huo, S., Yu, L., Xuan, X., Mou, W., Liu, P., et al. (2023) · Cellular and Molecular Biology · doi:10.14715/cmb/2023.69.10.38 · Cited by 1 · see citing works

Integrative omics analysis reveals gene regulatory mechanisms distinguishing organoid-derived hepatocytes from primary human hepatocytesPreprint

Wu, H., Yang, A., Stelloo, S., Roos, F. J. M., Morsche, R. H. M. T., Verkerk, A. H., Velez, M. V. L., Wingens, L. J. A., de Wilt, J. H. W., Sauerwein, R. W., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.05.570132 · Cited by 1 · see citing works

Fosl2 regulates the transition from parietal epithelial cells to myofibroblasts in the kidneyPreprint

Bronstein, R. D., Revelo, M. P., Sheikh, F. D., Haley, J. D., D’Agati, V. D., Salant, D. J., He, C., Guo, Y., & Mallipattu, S. K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.10.687667 · Cited by 1 · see citing works

Identification of hub genes and pathways in nonalcoholic steatohepatitis by integrated bioinformatics analysisPreprint

Einaliyan, P., Owfi, A., Mahmanzar, M., Aghajanzadeh, T., Hadizadeh, M., Sharifi‐Zarchi, A., Hatami, B., Aghdaei, H. A., Zali, M. R., & Baghaei, K. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.10.459743

Lower hepatotoxicity risk in Xelaglifam, a novel GPR40 agonist, compared to Fasiglifam for type 2 diabetes therapy

Yoon, J., Song, H., Park, J. S., Kim, J. H., Jun, Y., Gim, S.-A., Hong, C., An, K. M., Park, J.-T., Lee, J. W., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117674

Unveiling ; Osteopontin Role in Chronic Liver Disease: Insight and Implication

Pandalingal, M. F., & El-Hakeem, A. (2025) · doi:10.38124/ijisrt/25jun817

Evolutionarily conserved temperature dependence leads to loss of protein O-GlcNAc in mammalian hypothermiaPreprint

Upadhyay, D., Kietz, C., Sultana, N., Banerjee, R., Gaetani, M., Kankare, M., Fellman, V., Purhonen, J., & Kallijärvi, J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.08.660373

Identification of CTSK as a TLR-related critical biomarker in liver cirrhosis via integrative bioinformatics and pathological characterization

Wang, J., Li, N., Cang, X., Liu, X., Gao, R., Xu, L., Li, F., Jiang, X., Chen, H., Geng, X., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-11606-6

Additional file 1 of HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients

Brochado, Ó., Martínez, I., Berenguer, J., Medrano, L. M., González‐García, J., Jiménez-Sousa, M., Carrero, A., Hontañón, V., Navarro, J., Guardiola, J. M., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14344093

Additional file 4 of HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients

Brochado, Ó., Martínez, I., Berenguer, J., Medrano, L. M., González‐García, J., Jiménez-Sousa, M., Carrero, A., Hontañón, V., Navarro, J., Guardiola, J. M., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14344102

Additional file 5 of HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients

Brochado, Ó., Martínez, I., Berenguer, J., Medrano, L. M., González‐García, J., Jiménez-Sousa, M., Carrero, A., Hontañón, V., Navarro, J., Guardiola, J. M., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14344105

Additional file 7 of HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients

Brochado, Ó., Martínez, I., Berenguer, J., Medrano, L. M., González‐García, J., Jiménez-Sousa, M., Carrero, A., Hontañón, V., Navarro, J., Guardiola, J. M., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14344111

The transcription factor c-Jun/AP-1 affects non-alcoholic steatohepatitis (NASH) and liver fibrosis in a cell-type specific manner

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Increased expression of c-Jun in nonalcoholic fatty liver disease

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Progress in understanding the pathogenesis of nonalcoholic fatty liver disease

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Su1550 – Aortic Carboxypeptidase-Like Protein Promotes Hepaatocellular Carcinoma Progression in Nonalcoholic Fatty Liver Disease in Mice by Activating Canonical Wint Signaling

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NKT-Associated Hedgehog and Osteopontin Drive Fibrogenesis in Non-Alcoholic Fatty Liver Disease

Syn, W.-K., Agboola, K. M., Swiderska, M., Michelotti, G. A., Liaskou, E., Pang, H., Xie, G., Philips, G., Chan, I. S., Karaca, G. F., et al. (2012) · Gut · doi:10.1136/gutjnl-2011-301857 · Cited by 266 · see citing works