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Cited by 2Medication Adherence and ComplianceGlaucoma and retinal disordersTelemedicine and Telehealth Implementation

The DOI matches its Crossref record.

Adherence to topical glaucoma therapy in patients attending virtual clinics

Open access
Cheng, Kelvin K. W., Young, Su Ling, Donaldson, Sarah, Malcolm, Tej Rene, Tatham, Andrew J.·2023·Eye
DOI 10.1038/s41433-022-02277-yPMC PMC10275896
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Abstract

Background/objectives Poor adherence to medical therapy is a major challenge to the effective treatment of chronic diseases including glaucoma. Potential factors influencing adherence include treatment complexity and patient understanding of disease and health beliefs. An increasing number of patients are seen in virtual clinics, where there is no face-to-face consultation, potentially reducing opportunities for patient education and reinforcement of the importance of treatment. The aim of this study was to examine adherence among patients attending a virtual glaucoma clinic. Methods 100 consecutive patients attending the virtual clinic were surveyed, with 78 using topical medications included in the analysis. All patients completed a validated adherence questionnaire with a score of >2 defined as poor adherence. The relationship between adherence and age, sex, duration since diagnosis, and disease severity was examined. Results The mean age was 73.1 ± 13.4 years, with an average mean deviation of -5.9 ± 5.5 dB and duration since first diagnosis of 9.0 ± 5.7 years. 93.6% reported self-instilling eye drops. Seventy-one patients (91.0 %) had good self-reported adherence. Multivariate logistic regression revealed those instilling eye drops independently had higher odds of good adherence. Conclusions The level of medication adherence in the virtual glaucoma clinic was higher than adherence in previous studies examining patients attending face-to-face clinics. Virtual clinics should incorporate methods to ensure effective two-way communication with patients and strategies for patient education.

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Research works printed but not linked: 25

  1. Chalk D, Smith M. Guidelines on glaucoma and the demand for services. Br J Health Manag. 2013;19:476–81.
  2. Clarke J, Puertas R, Kotecha A, Foster PJ, Barton K. Virtual clinics in glaucoma care: face-to-face versus remote decision-making. Br J Ophthalmol. 2017;101:892–5. · DOI
  3. Gunn PJG, Marks JR, Au L, Read S, Waterman H, Spry PGD, et al. Virtual clinics for glaucoma care—patients’ and clinicians’ experiences and perceptions: a qualitative evaluation. Eye 2022;36:209–18. · DOI
  4. Stewart WC, Chorak RP, Hunt HH, Sethuraman G. Factors associated with visual loss in patients with advanced glaucomatous changes in the optic nerve head. Am J Ophthalmol. 1993;116:176–81. · DOI
  5. Schwartz GF, Quigley HA. Adherence and persistence with glaucoma therapy. Surv Ophthalmol. 2008;53(Suppl1):S57–68. · DOI
  6. Friedman DS, Hahn SR, Gelb L, Tan J, Shah SN, Kim EE, et al. Doctor-patient communication, health-related beliefs, and adherence in glaucoma results from the Glaucoma Adherence and Persistency Study. Ophthalmology 2008;115:1320–7. 1327.e1-3 · DOI
  7. Lacey J, Cate H, Broadway DC. Barriers to adherence with glaucoma medications: a qualitative research study. Eye 2009;23:924–32. · DOI
  8. Waterman H, Brunton L, Fenerty C, Mottershead J, Richardson C, Spencer F. Adherence to ocular hypotensive therapy: patient health education needs and views on group education. Patient Prefer Adherence. 2013;7:55–63. · DOI
  9. Newman-Casey PA, Robin AL, Blachley T, Farris K, Heisler M, Resnicow K, et al. The most common barriers to glaucoma medication adherence: a cross-sectional survey. Ophthalmology 2015;122:1308–16. · DOI
  10. Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens. 2008;10:348–54. · DOI · Paper page
  11. de Oliveira-Filho AD, Morisky DE, Neves SJF, Costa FA, de Lyra DP. The 8-item Morisky Medication Adherence Scale: validation of a Brazilian-Portuguese version in hypertensive adults. Res Soc Adm Pharm. 2014;10:554–61. · DOI
  12. Lee WY, Ahn J, Kim JH, Hong YP, Hong SK, Kim YT, et al. Reliability and validity of a self-reported measure of medication adherence in patients with type 2 diabetes mellitus in Korea. J Int Med Res. 2013;41:1098–110. · DOI
  13. Aggarwal S, Paul G, Paul BS, Mahendru D, Goyal S. Factors affecting adherence to pharmacotherapy in Parkinson’s disease. Ann Indian Acad Neurol. 2021;24:879–84. · DOI
  14. Kawakami A, Tanaka M, Choong LM, Kunisaki R, Maeda S, Bjarnason I, et al. Self-reported medication adherence among patients with ulcerative colitis in Japan and the United Kingdom: a secondary analysis for cross-cultural comparison. Patient Prefer Adherence. 2022;16:671–8. · DOI
  15. Sleath B, Blalock S, Covert D, Stone JL, Skinner AC, Muir K, et al. The relationship between glaucoma medication adherence, eye drop technique, and visual field defect severity. Ophthalmology 2011;118:2398–402. · DOI
  16. De Amici D, Klersy C, Ramajoli F, Brustia L, Politi P. Impact of the Hawthorne effect in a longitudinal clinical study: the case of anesthesia. Control Clin Trials. 2000;21:103–14. · DOI
  17. Okeke CO, Quigley HA, Jampel HD, Ying GS, Plyler RJ, Jiang Y, et al. Adherence with topical glaucoma medication monitored electronically the Travatan Dosing Aid study. Ophthalmology 2009;116:191–9. · DOI
  18. Boland MV, Zhang L, Broman AT, Jampel HD, Quigley HA. Comparison of optic nerve head topography and visual field in eyes with open-angle and angle-closure glaucoma. Ophthalmology 2008;115:239–245.e2. · DOI
  19. Boland MV, Chang DS, Frazier T, Plyler R, Friedman DS. Electronic monitoring to assess adherence with once-daily glaucoma medications and risk factors for nonadherence: the automated dosing reminder study. JAMA Ophthalmol. 2014;132:838–44. · DOI
  20. Friedman DS, Quigley HA, Gelb L, Tan J, Margolis J, Shah SN, et al. Using pharmacy claims data to study adherence to glaucoma medications: methodology and findings of the Glaucoma Adherence and Persistency Study (GAPS). Investig Ophthalmol Vis Sci. 2007;48:5052–7. · DOI
  21. Robin AL, Muir KW. Medication adherence in patients with ocular hypertension or glaucoma. Expert Rev Ophthalmol. 2019;14:199–210. · DOI
  22. Cho J, Niziol LM, Lee PP, Heisler M, Resnicow K, Musch DC, et al. Comparison of medication adherence assessment tools to identify glaucoma medication nonadherence. Ophthalmol Glaucoma. 2022;5:137–45. · DOI
  23. Waterman H, Evans JR, Gray TA, Henson D, Harper R. Interventions for improving adherence to ocular hypotensive therapy. Cochrane Database Syst Rev. 2013;CD006132. · DOI
  24. Daniels B, Healey P, Bruno C, Kaan I, Zoega H. Medicine treatment of glaucoma in Australia 2012–2019: prevalence, incidence and persistence. BMJ Open Ophthalmol. 2021;6:e000921. · DOI
  25. Hwang DK, Liu CJL, Pu CY, Chou YJ, Chou P. Persistence of topical glaucoma medication: a nationwide population-based cohort study in Taiwan. JAMA Ophthalmol. 2014;132:1446–52. · DOI

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Metadata

Authors
Cheng, K. K. W., Young, S. L., Donaldson, S., Malcolm, T. R., & Tatham, A. J.
Affiliations
Princess Alexandra Eye Pavilion (GB)
Corresponding author
Tatham, Andrew J.
ORCID
Venue
Eye
Publisher
Springer Science and Business Media LLC
Published
2022-10-08
Volume
37
Issue
9
Pages
1922-1927
ISSN
  • 0078-5334 (ISSN-L)
  • 0950-222X
  • 1476-5454
DOI
10.1038/s41433-022-02277-y
PMC
PMC10275896
OpenAlex
W4303646983
Cited by
2
References
0
Citations by year
2026: 1 · 2024: 1
FWCI
0.27
Type
journal article
Language
en
Open access
Licence
Locations
  • Eye (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
NHS Scotland Research Clinician Grant
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Ophthalmology › Glaucoma and retinal disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
Keywords
glaucoma, medication adherence, eye drops, virtual clinics, telemedicine, patient education, treatment complexity, health beliefs, disease severity
MeSH terms
Aged, Aged, 80 and over, Antihypertensive Agents, Glaucoma, Humans, Middle Aged, Ophthalmic Solutions, Surveys and Questionnaires, Medication Adherence

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