Retracted: Predictive Validity of a Medication Adherence Measure in an Outpatient Setting
Open accessAbstract
This study examines the psychometric properties and tests the concurrent and predictive validity of a structured, self-reported medication adherence measure in patients with hypertension. The authors also assessed various psychosocial determinants of adherence, such as knowledge, social support, satisfaction with care, and complexity of the medical regimen. A total of 1367 patients participated in the study; mean age was 52.5 years, 40.8% were male, 76.5% were black, 50.8% graduated from high school, 26% were married, and 54.1% had income <$5,000. The 8-item medication adherence scale was reliable (alpha=.83) and significantly associated with blood pressure control (P<.05). Using a cutpoint of <6, the sensitivity of the measure to identify patients with poor blood pressure control was estimated to be 93%, and the specificity was 53%. The medication adherence measure proved to be reliable, with good concurrent and predictive validity in primarily low-income, minority patients with hypertension and might function as a screening tool in outpatient settings with other patient groups.
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It is unclear whether the differences on the MMAS-8 are of clinical significance, because the scores would still meet the cut-off for low adherence.
“however, it is unclear if the differences are of any clinical significance, as the scores on this measure would still meet the cut-off for 'low adherence'.”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Morisky 2008
The Results section defines MMAS-8 scores below 6 as low adherence, supporting the cited cut-off. The paper does not assess the particular score differences in the citing sentence or whether they are clinically significant; no page number is available in our copy. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThere was a difference of 1.72 in favour of the intervention on the MMAS-8.
“There was a difference of 1.72 in favour of the intervention on the MMAS-8 (Morisky 2008);”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Morisky 2008
The Methods section describes examination of the eight-item adherence measure, and the Results section reports its mean score and psychometric properties. Searches for “1.72” and an intervention-group difference found no passage reporting a 1.72-point MMAS-8 advantage for an intervention. (LLM, conf=0.75)
Experimental — accuracy not yet measured
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Percentages, sums and reported differences re-computed from the paper’s own numbers.
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Self-citation
- Authors
- Morisky, D. E., Ang, A., Krousel‐Wood, M., & Ward, H. J.
- Affiliations
- Tulane University (US)
- ORCID
- Morisky, Donald E.
- Venue
- The Journal of Clinical Hypertension
- Publisher
- Wiley
- Published
- 2008-05
- Volume
- 10
- Issue
- 5
- Pages
- 348-354
- ISSN
- 1524-6175 (ISSN-L)
- 1751-7176
- PMC
- PMC2562622
- OpenAlex
- W1966242613
- Cited by
- 2,877
- References
- 46
- Citations by year
- 2026: 91 · 2025: 155 · 2024: 178 · 2023: 229 · 2022: 201 · 2021: 217 · 2020: 223 · 2019: 199 · 2018: 229 · 2017: 254 · 2016: 207 · 2015: 217 · 2014: 176 · 2013: 110 · 2012: 78
- FWCI
- 25.99
- Type
- journal article
- Language
- en
- Status
- Retracted
- Update notices
- retraction (2023-08-18)
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Hypertension (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- U.S. Public Health Service (R0-H251119)
- National Institute on Aging (R01AG022536, AG022536)
- National Heart, Lung, and Blood Institute (T32HL007656)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- medication adherence, hypertension, predictive validity, concurrent validity, psychometric properties, blood pressure control, social support, treatment satisfaction, medication regimen complexity, screening tool, outpatient care
- MeSH terms
- Adolescent, Adult, Ambulatory Care, Antihypertensive Agents, Female, Follow-Up Studies, Humans, Hypertension, Male, Middle Aged, Patient Compliance, Patient Education as Topic, Physician-Patient Relations, Psychometrics, Surveys and Questionnaires, Treatment Outcome
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