The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
High-resolution spatiotemporal transcriptome mapping of tomato fruit development and ripening
Open accessAbstract
Tomato (Solanum lycopersicum) is an established model for studying fruit biology; however, most studies of tomato fruit growth and ripening are based on homogenized pericarp, and do not consider the internal tissues, or the expression signatures of individual cell and tissue types. We present a spatiotemporally resolved transcriptome analysis of tomato fruit ontogeny, using laser microdissection (LM) or hand dissection coupled with RNA-Seq analysis. Regulatory and structural gene networks, including families of transcription factors and hormone synthesis and signaling pathways, are defined across tissue and developmental spectra. The ripening program is revealed as comprising gradients of gene expression, initiating in internal tissues then radiating outward, and basipetally along a latitudinal axis. We also identify spatial variations in the patterns of epigenetic control superimposed on ripening gradients. Functional studies elucidate previously masked regulatory phenomena and relationships, including those associated with fruit quality traits, such as texture, color, aroma, and metabolite profiles.
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Cited by
The tomato pan-genome uncovers new genes and a rare allele regulating fruit flavor
Gao, L., Gonda, I., Sun, H., Ma, Q., Bao, K., Tieman, D. M., Burzynski-Chang, E. A., Fish, T. L., Stromberg, K. A., Sacks, G. L., et al. (2019) · Nature Genetics · doi:10.1038/s41588-019-0410-2 · Cited by 717
Self-citation5Gs for crop genetic improvement
Varshney, R. K., Sinha, P., Singh, V. K., Kumar, A., Zhang, Q., & Bennetzen, J. L. (2020) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2019.12.004 · Cited by 257
Metadata
- Authors
- Shinozaki, Y., Nicolas, P., Fernandez-Pozo, N., Ma, Q., Evanich, D. J., Shi, Y., Xu, Y., Zheng, Y., Snyder, S. I., Martin, L. B. B., Ruiz-May, E., Thannhauser, T. W., Chen, K., Domozych, D. S., Catalá, C., Fei, Z., Mueller, L. A., Giovannoni, J. J., & Rose, J. K. C.
- Venue
- Nature Communications
- Published
- 2018-01-25
- Volume
- 9
- Issue
- 1
- Pages
- 364-364
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2794820198
- Cited by
- 391
- References
- 73
- FWCI
- 33.78
- Type
- journal article
- Language
- en
- Open access
- gold
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- Shinozaki, Y., Nicolas, P., Fernandez-Pozo, N., Ma, Q., Evanich, D. J., Shi, Y., Xu, Y., Zheng, Y., Snyder, S. I., Martin, L. B. B., Ruiz-May, E., Thannhauser, T. W., Chen, K., Domozych, D. S., Catalá, C., Fei, Z., Mueller, L. A., Giovannoni, J. J., & Rose, J. K. C. (2018). High-resolution spatiotemporal transcriptome mapping of tomato fruit development and ripening. Nature Communications. https://doi.org/10.1038/s41467-017-02782-9
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