The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
Open accessAbstract
Particle trapping and binding in optical potential wells provide a versatile platform for various biomedical applications. However, implementation systems to study multi-particle contact interactions in an optical lattice remain rare. By configuring an optofluidic lattice, we demonstrate the precise control of particle interactions and functions such as controlling aggregation and multi-hopping. The mean residence time of a single particle is found considerably reduced from 7 s, as predicted by Kramer’s theory, to 0.6 s, owing to the mechanical interactions among aggregated particles. The optofluidic lattice also enables single-bacteria-level screening of biological binding agents such as antibodies through particle-enabled bacteria hopping. The binding efficiency of antibodies could be determined directly, selectively, quantitatively and efficiently. This work enriches the fundamental mechanisms of particle kinetics and offers new possibilities for probing and utilising unprecedented biomolecule interactions at single-bacteria level.
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Reaction-rate theory: fifty years after Kramers
Hänggi, P., Talkner, P., & Borkovec, M. (1990) · Reviews of Modern Physics · doi:10.1103/revmodphys.62.251 · Cited by 6,154
Single-cell genome sequencing: current state of the science
Gawad, C., Koh, W., & Quake, S. R. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2015.16 · Cited by 1,334
Single-molecule fluorescence spectroscopy maps the folding landscape of a large protein
Pirchi, M., Ziv, G., Riven, I., Cohen, S. S., Zohar, N., Barak, Y., & Haran, G. (2011) · Nature Communications · doi:10.1038/ncomms1504 · Cited by 179
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Self-citationMetasurface Micro/Nano-Optical Sensors: Principles and Applications
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Song, Q., Liu, X., Qiu, C.-W., & Genevet, P. (2022) · Applied Physics Reviews · doi:10.1063/5.0078610 · Cited by 139
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Metadata
- Authors
- Shi, Y. Z., Xiong, S., Zhang, Y., Chin, L. K., Chen, Y. –., Zhang, J. B., Zhang, T. H., Ser, W., Larrson, A., Lim, S. H., Wu, J. H., Chen, T. N., Yang, Z. C., Hao, Y. L., Liedberg, B., Yap, P. H., Wang, K., Tsai, D. P., Qiu, C.-W., & Liu, A. Q.
- Venue
- Nature Communications
- Published
- 2018-02-26
- Volume
- 9
- Issue
- 1
- Pages
- 815-815
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2800654689
- Cited by
- 176
- References
- 3
- FWCI
- 10.63
- Type
- journal article
- Language
- en
- Open access
- gold
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- Shi, Y. Z., Xiong, S., Zhang, Y., Chin, L. K., Chen, Y. –., Zhang, J. B., Zhang, T. H., Ser, W., Larrson, A., Lim, S. H., Wu, J. H., Chen, T. N., Yang, Z. C., Hao, Y. L., Liedberg, B., Yap, P. H., Wang, K., Tsai, D. P., Qiu, C.-W., & Liu, A. Q. (2018). Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement. Nature Communications. https://doi.org/10.1038/s41467-018-03156-5
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