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Cited by 304

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies

Open access
Yan, Huili, Xu, Wenxiu, Xie, Jianyin, Gao, Yiwei, Wu, Lulu, Sun, Liang, Feng, Lu, Chen, Xu, Zhang, Tian, Dai, Changhua, Li, Ting, Lin, Xiuni, Zhang, Zhanying, Wang, Xueqiang, Li, Fengmei, Zhu, Xiaoyang, Li, Jinjie, Li, Zichao, Chen, Caiyan, Ma, Mi, Zhang, Hongliang, He, Zhenyan·2019·Nature Communications

Abstract

Cadmium (Cd) accumulation in rice grain poses a serious threat to human health. While several transport systems have been reported, the complexity of rice Cd transport and accumulation indicates the necessity of identifying additional genes, especially those that are responsible for Cd accumulation divergence between indica and japonica rice subspecies. Here, we show that a gene, OsCd1, belonging to the major facilitator superfamily is involved in root Cd uptake and contributes to grain accumulation in rice. Natural variation in OsCd1 with a missense mutation Val449Asp is responsible for the divergence of rice grain Cd accumulation between indica and japonica. Near-isogenic line tests confirm that the indica variety carrying the japonica allele OsCd1V449 can reduce the grain Cd accumulation. Thus, the japonica allele OsCd1V449 may be useful for reducing grain Cd accumulation of indica rice cultivars through breeding.

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Metadata

Authors
Yan, H., Xu, W., Xie, J., Gao, Y., Wu, L., Sun, L., Feng, L., Chen, X., Zhang, T., Dai, C., Li, T., Lin, X., Zhang, Z., Wang, X., Li, F., Zhu, X., Li, J., Li, Z., Chen, C., Ma, M., Zhang, H., & He, Z.
Venue
Nature Communications
Published
2019-06-12
Volume
10
Issue
1
Pages
2562-2562
ISSN
2041-1723 (ISSN-L)
OpenAlex
W2952505940
Cited by
304
References
53
FWCI
9.42
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies. https://app.cochat.ai/papers/10.1038/s41467-019-10544-y
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Yan, H., Xu, W., Xie, J., Gao, Y., Wu, L., Sun, L., Feng, L., Chen, X., Zhang, T., Dai, C., Li, T., Lin, X., Zhang, Z., Wang, X., Li, F., Zhu, X., Li, J., Li, Z., Chen, C., . . . He, Z. (2019). Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies. Nature Communications. https://doi.org/10.1038/s41467-019-10544-y

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