The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Systematic and quantitative view of the antiviral arsenal of prokaryotes
Open accessAbstract
Bacteria and archaea have developed multiple antiviral mechanisms, and genomic evidence indicates that several of these antiviral systems co-occur in the same strain. Here, we introduce DefenseFinder, a tool that automatically detects known antiviral systems in prokaryotic genomes. We use DefenseFinder to analyse 21000 fully sequenced prokaryotic genomes, and find that antiviral strategies vary drastically between phyla, species and strains. Variations in composition of antiviral systems correlate with genome size, viral threat, and lifestyle traits. DefenseFinder will facilitate large-scale genomic analysis of antiviral defense systems and the study of host-virus interactions in prokaryotes.
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Virtanen, P., Gommers, R., Oliphant, T. E., Haberland, M., Reddy, T., Cournapeau, D., Burovski, E., Peterson, P., Weckesser, W., Bright, J., et al. (2020) · Nature Methods · doi:10.1038/s41592-019-0686-2 · Cited by 38,430
IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era
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Self-citationDiscovery of phage determinants that confer sensitivity to bacterial immune systems
Stokar-Avihail, A., Fedorenko, T., Hör, J., Garb, J., Leavitt, A., Millman, A., Shulman, G., Wojtania, N., Melamed, S., Amitai, G., et al. (2023) · Cell · doi:10.1016/j.cell.2023.02.029 · Cited by 176
Gaborieau, B., Vaysset, H., Tesson, F., Charachon, I., Dib, N., Bernier, J., Dequidt, T., Georjon, H., Clermont, O., Hersen, P., et al. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01832-5 · Cited by 141
Structural basis of Gabija anti-phage defence and viral immune evasion
Antine, S. P., Johnson, A. G., Mooney, S. E., Leavitt, A., Mayer, M. L., Yirmiya, E., Amitai, G., Sorek, R., & Kranzusch, P. J. (2024) · Nature · doi:10.1038/s41586-023-06855-2 · Cited by 125
Metadata
- Authors
- Tesson, F., Hervé, A., Mordret, E., Touchon, M., d’Humières, C., Cury, J., & Bernheim, A.
- Venue
- Nature Communications
- Published
- 2022-05-10
- Volume
- 13
- Issue
- 1
- Pages
- 2561-2561
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W4229443239
- Cited by
- 759
- References
- 4
- FWCI
- 70.19
- Type
- journal article
- Language
- en
- Open access
- gold
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