The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Antibiotic resistance increases with local temperature
Open accessAbstract
Bacteria that cause infections in humans can develop or acquire resistance to antibiotics commonly used against them1,2. Antimicrobial resistance (in bacteria and other microbes) causes significant morbidity worldwide, and some estimates indicate the attributable mortality could reach up to 10 million by 20502–4. Antibiotic resistance in bacteria is believed to develop largely under the selective pressure of antibiotic use; however, other factors may contribute to population level increases in antibiotic resistance1,2. We explored the role of climate (temperature) and additional factors on the distribution of antibiotic resistance across the United States, and here we show that increasing local temperature as well as population density are associated with increasing antibiotic resistance (percent resistant) in common pathogens. We found that an increase in temperature of 10 °C across regions was associated with an increases in antibiotic resistance of 4.2%, 2.2%, and 2.7% for the common pathogens Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. The associations between temperature and antibiotic resistance in this ecological study are consistent across most classes of antibiotics and pathogens and may be strengthening over time. These findings suggest that current forecasts of the burden of antibiotic resistance could be significant underestimates in the face of a growing population and climate change4.Based on an analysis of the distribution of antibiotic resistance across the United States, research shows that increasing local temperatures as well as population density across regions are associated with increasing antibiotic resistance in common bacterial pathogens.
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Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
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Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
Goossens, H., Ferech, M., Vander Stichele, R., & Elseviers, M. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17907-0 · Cited by 3,359
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Understanding the mechanisms and drivers of antimicrobial resistance
Holmes, A. H., Moore, L. S. P., Sundsfjord, A., Steinbakk, M., Regmi, S., Karkey, A., Guerin, P. J., & Piddock, L. J. V. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00473-0 · Cited by 2,611
Hospital-Acquired Infections Due to Gram-Negative Bacteria
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Relationship between temperature and growth rate of bacterial cultures
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Cited by
Zheng, D., Yin, G., Liu, M., Chen, C., Jiang, Y., Hou, L., & Zheng, Y. (2021) · Science of The Total Environment · doi:10.1016/j.scitotenv.2021.146009 · Cited by 348
Coque, T. M., Cantón, R., Pérez-Cobas, A. E., Fernández-de-Bobadilla, M. D., & Baquero, F. (2023) · Microorganisms · doi:10.3390/microorganisms11041050 · Cited by 258
Climate change impact on migration, travel, travel destinations and the tourism industry
Semenza, J. C., & Ebi, K. L. (2019) · Journal of Travel Medicine · doi:10.1093/jtm/taz026 · Cited by 104
Mitchell, J., Cooke, P., Ahorlu, C., Arjyal, A., Baral, S., Carter, L., Dasgupta, R., Fieroze, F., Fonseca-Braga, M., Huque, R., et al. (2022) · Global Public Health · doi:10.1080/17441692.2021.2003839 · Cited by 94
Parker, E. R., Mo, J., & Goodman, R. S. (2022) · The Journal of Climate Change and Health · doi:10.1016/j.joclim.2022.100162 · Cited by 58
Metadata
- Authors
- MacFadden, D. R., McGough, S. F., Fisman, D., Santillana, M., & Brownstein, J. S.
- Venue
- Nature Climate Change
- Published
- 2018-05-21
- Volume
- 8
- Issue
- 6
- Pages
- 510-514
- ISSN
- 1758-678X (ISSN-L)
- 1758-6798
- OpenAlex
- W2803599078
- Cited by
- 560
- References
- 26
- FWCI
- 20.50
- Type
- journal article
- Language
- en
- Open access
- green
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- MacFadden, D. R., McGough, S. F., Fisman, D., Santillana, M., & Brownstein, J. S. (2018). Antibiotic resistance increases with local temperature. Nature Climate Change. https://doi.org/10.1038/s41558-018-0161-6
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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