Identification of nucleoside monophosphates and their epigenetic modifications using an engineered nanopore

Dynamic RNA Modifications in Gene Expression Regulation

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Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore

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MODOMICS: a database of RNA modification pathways. 2017 update

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Role of RNA modifications in cancer

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5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader

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The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA

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Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

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Review and perspective of single-molecule spectroscopy for chemistry

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Dual Ionic Signal Detection: Modulation of Surface Charge of Nanofluidic Iontronics by Dual-Split Gate Voltages

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Nanopore‐Based Single‐Molecule Logic Unit (sMOLU)

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Decoding information stored in DNAs through single-molecule electrical detection platforms

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Selective and Controllable Trapping of Single Proteins in Nanopores Using Reversible Covalent Bonds

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Nanotechnology and machine learning synergies for improving the bioavailability and functional efficacy of dietary polyphenols

Wu, W., Mei, B., Wu, Y., Liu, L., Wang, Y., Lombardo, M., & Yang, H. (2026) · Food Research International · doi:10.1016/j.foodres.2026.118499 · Cited by 2

Scalable Production of DNA-Probe-Functionalized Heteromeric MspA Nanopores for Biosensing

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In situ and real-time monitoring of intracellular activities in single live cells using a nanopore probe

Huang, X., Li, Z., Huang, Y., Zhou, K., Liu, L., & Wu, H. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2529161123 · Cited by 2

Multiscale Theoretical Calculations Drive Mechanism Analysis and Application Expansion of Nanopore Detection

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Real-time identification of multiple nanoclusters with a protein nanopore in single-cluster level

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Electrochemical Visualization of Single-Molecule Thiol Substitution with Nanopore Measurement

Yang, C., Liu, W., Liu, H., Zhang, J., Yu, R., Ying, Y., & Long, Y. (2023) · ACS Measurement Science Au · doi:10.1021/acsmeasuresciau.3c00046 · Cited by 2

Single molecular profile of proteins sensing by nanopore technology

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Engineered Nanofluidics for Molecular Recognition and Physical Perception

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Nanopore-based Single-molecule DNA Sequencing★

Bai, H., Tan, H., & Feng, J. (2025) · 化学学报 · doi:10.6023/a25050179 · Cited by 1

Transforming from ‘natural tools’ into ‘custom sensors’: combining directionally designed biological nanopore electrochemistry sensing lumens with AI-driven analytics to pioneer a new paradigm for food analysis

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Quantitative Sensing of Monosaccharide Isomers with High Resolution and Attomolar Limit of Detection

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The evolutionary strategies for enhanced nanopore sensing

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High-resolution nanopore peptide sensing, profiling and sequence assembly

Wang, K., An, X., Gao, X., Ouyang, Y., Wang, Z., Fan, P., Li, K., Xiao, Y., Jia, W., Chen, J., et al. (2026) · Nature Nanotechnology · doi:10.1038/s41565-026-02192-3 · Cited by 1

Nanopore Polyphenol Fingerprinting with Anthocyanin–Catechin Signatures for Tea Quality Grading and Cultivar Discrimination

Fan, P., Li, J., Sun, Y., Zhang, X., & Yu, M. (2026) · Nano Letters · doi:10.1021/acs.nanolett.6c01886 · Cited by 1

Radical-Induced Dissociation for Oligonucleotide Sequencing by TiO2/ZnAl-Layered Double Oxide-Assisted Laser Desorption/Ionization Mass Spectrometry

Zhou, S., Qi, M., Luo, Y., Li, W., Liu, Y., Guo, C., Wei, W., Chen, G., Tu, P., Feng, H., et al. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c02166 · Cited by 1

Nanopore sensitization based on a double loop hybridization chain reaction and G-quadruplex

Li, Y., Yu, C., Wang, Y., Yu, J. Z., Wang, H., & Li, B. (2024) · Chemical Communications · doi:10.1039/d4cc00125g · Cited by 1

Opportunities and challenges of single molecule science

Li, C., Jia, C., & Guo, X. (2023) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2022-1112 · Cited by 1

Nanopores distinguish RNA modifications

Tang, L. (2022) · Nature Methods · doi:10.1038/s41592-022-01614-z

Omics Sciences in Drug Discovery, Safety, and Pharmacokinetics

Giovanni, T., Giannese, F., & Lazarević, D. (2024) · Springer eBooks · doi:10.1007/978-3-030-73317-9_131-1

Omics Sciences in Drug Discovery, Safety, and Pharmacokinetics

Tonon, G., Giannese, F., & Lazarević, D. (2024) · Springer eBooks · doi:10.1007/978-3-031-35529-5_131

Pore lipid modifications modulate MscS nanopore for enhanced single-molecule sensing

Zhao, C., Mou, X., Zhang, Q., Chen, C., Zhu, Y., Hong, L., Liu, H., Wu, J., Geng, J., & Bao, R. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117250

Advances in the application of machine learning in nanomedicine

Zhao, C., Liu, X., Guan, L., Wang, C., & Deng, H. (2025) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/csb-2025-5259

Revealing Single-Amino Acid Recognition and Cleavage Dynamics Using Plasmonic Biosensors

Chang, S., Sheng, X., Deng, Y., Shen, M., Wang, D., Liu, L., Li, W. J., Kong, J., Nie, A., Mu, C., et al. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c04078

Tailoring Vibrio ‐Type Secretin Channel Protein GspD Toward “One‐Take” Dual‐Constriction Nanopore Sensors

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Probing the Identification of Single Modification Sites in Short RNA Strands

Han, Y. K., Zhu, L., Li, D., Li, G., Zhang, Y., Zhang, Y., & Dong, Z. (2025) · Journal of Raman Spectroscopy · doi:10.1002/jrs.70094

Engineering of a Nucleoside 2′-Deoxyribosyltransferase for Efficient Catalysis of 5-Halogenated-2′-Deoxypyrimidine Nucleosides via Active-Site Channel Expansion

Zhou, J., Jiang, Y., He, Y., Ma, L., Yue, X., Zhou, L., Liu, G., & Zheng, X. (2026) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-026-05756-0

Molecular Encoding during Amplification Enables Multiplex Nanopore Profiling of Small Noncoding RNAs

Liu, M., Zhang, H., Guo, S., Du, X., Xiao, X., & Wang, Y. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.6c01314

β-Cyclodextrin-Functionalized Mycobacterium smegmatis Porin A for Steroid Discrimination and Gut Metabolite Monitoring

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Optical and Electrical Characterization of Nanopores in Freestanding Lipid Bilayers Formed on Microelectrode Cavity Arrays

Handyside, M. A., Harvey, J. S., Lee, S., Michael, K. A., Sennese, K. R., Evenson, A., Koeneman, S., Burden, D. L., & Keranen‐Burden, L. M. (2026) · Methods in molecular biology · doi:10.1007/978-1-0716-5527-6_8

Engineering a Monomeric Nanopore Scaffold for Multiplexed Protein Detection

Foster, J. C., & Chen, M. (2026) · Methods in molecular biology · doi:10.1007/978-1-0716-5527-6_6

Nanopore-enabled time-resolved monitoring of catecholamine-related phenylalanine metabolism

Zhang, M., Li, Z., Hao, W., Yi, Y., Zhou, K., Liu, L., & Wu, H. (2026) · Nature Nanotechnology · doi:10.1038/s41565-026-02273-3

Single-Molecule Monitoring of Formaldehyde–Lysine Residue Chemistry using an Engineered MspA Nanopore

Du, X., Cao, Q., Fan, N., & Wang, Y. (2026) · Nano Letters · doi:10.1021/acs.nanolett.6c02512

An engineered nanopore identifies saccharides, amino acids, peptides and ribonucleotides

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A Peptidoglycan-Mimetic Nanopore Receptor Resolves Glycopeptide Antibiotic Recognition and Resistance at the Single-Molecule Level

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A review of analytical techniques for characterization of mRNA drug substance in therapeutics and their suitability as a multi-attribute method

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Nanopore Signatures of High-Molecular-Weight Polysaccharides with Recurring Structural Motifs

Li, W., Xiao, Y., Gao, X., Zhang, P., Huang, S., & Wang, K. (2026) · ACS Nano · doi:10.1021/acsnano.6c07846

Modification Detection using Nanopore Sequencing

Bailey, A. D. (2021) · eScholarship (California Digital Library)

Systematic assessment of diverse RNA modifications using nanopore direct RNA sequencing

Kang, X., Zhang, K., Goyon, A., & Stephenson, W. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag411 · Cited by 9

Computational methods for RNA modification detection from nanopore direct RNA sequencing data

Furlan, M., Delgado-Tejedor, A., Mulroney, L., Pelizzola, M., Novoa, E. M., & Leonardi, T. (2021) · RNA Biology · doi:10.1080/15476286.2021.1978215 · Cited by 111

Direct detection of RNA modifications and structure using single-molecule nanopore sequencing

Stephenson, W., Razaghi, R., Busan, S., Weeks, K. M., Timp, W., & Smibert, P. (2022) · Cell Genomics · doi:10.1016/j.xgen.2022.100097 · Cited by 162

SmartImage: A Machine Learning Method for Nanopore Identifying Chemical Modifications on RNA

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