The DOI matches its Crossref record; 219 of the 219 references it cites were found in a registry or an index.
Engineering the multiscale complexity of vascular networks
Open accessAbstract
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and nutrients through vascular networks that pervade nearly all tissues in the body. Dysregulation of these vascular networks is implicated in many common human diseases such as hypertension, coronary artery disease, diabetes and cancer. Therefore, engineers have sought to create vascular networks within engineered tissues for applications such as regenerative therapies, human disease modelling and pharmacological testing. Yet engineering vascular networks has historically remained difficult, owing to both incomplete understanding of vascular structure and technical limitations for vascular fabrication. This Review highlights the materials advances that have enabled transformative progress in vascular engineering by ushering in new tools for both visualizing and building vasculature. New methods such as bioprinting, organoids and microfluidic systems are discussed, which have enabled the fabrication of 3D vascular topologies at a cellular scale with lumen perfusion. These approaches to vascular engineering are categorized into technology-driven and nature-driven approaches. Finally, the remaining knowledge gaps, emerging frontiers and opportunities for this field are highlighted, including the steps required to replicate the multiscale complexity of vascular networks found in nature.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Langer, R., & Vacanti, J. P. (1993) · Science · doi:10.1126/science.8493529 · Cited by 9,893
Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association
Virani, S. S., Alonso, A., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Delling, F. N., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000757 · Cited by 9,175
3D bioprinting of tissues and organs
Murphy, S. V., & Atala, A. (2014) · Nature Biotechnology · doi:10.1038/nbt.2958 · Cited by 7,034
Geometric Control of Cell Life and Death
Chen, C. S., Mrksich, M., Huang, S., Whitesides, G. M., & Ingber, D. E. (1997) · Science · doi:10.1126/science.276.5317.1425 · Cited by 4,710
Bhatia, S. N., & Ingber, D. E. (2014) · Nature Biotechnology · doi:10.1038/nbt.2989 · Cited by 3,305
Modeling Development and Disease with Organoids
Clevers, H. (2016) · Cell · doi:10.1016/j.cell.2016.05.082 · Cited by 3,196
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
Kang, H.-W., Lee, S. J., Ko, I. K., Kengla, C., Yoo, J. J., & Atala, A. (2016) · Nature Biotechnology · doi:10.1038/nbt.3413 · Cited by 2,622
Molecular regulation of vessel maturation
Jain, R. K. (2003) · Nature Medicine · doi:10.1038/nm0603-685 · Cited by 2,594
Vascularized and functional human liver from an iPSC-derived organ bud transplant
Takebe, T., Sekine, K., Enomura, M., Koike, H., Kimura, M., Ogaeri, T., Zhang, R.-R., Ueno, Y., Zheng, Y.-W., Koike, N., et al. (2013) · Nature · doi:10.1038/nature12271 · Cited by 2,170
Self-citationMonteil, V., Kwon, H., Prado, P., Hagelkrüys, A., Wimmer, R. A., Stahl, M., Leopoldi, A., Garreta, E., Hurtado del Pozo, C., Prosper, F., et al. (2020) · Cell · doi:10.1016/j.cell.2020.04.004 · Cited by 2,122
Cited by
Sorted by citations
Items 101–200 of 271
Tamo, A. K., Doench, I., Roshanbinfar, K., Montembault, A., Serghei, A., Engel, F. B., & Osorio‐Madrazo, A. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.05.014 · Cited by 14
Interfacial Polyelectrolyte Complexation-Inspired Bioprinting of Vascular Constructs
Liu, C., & Tong, Y. W. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c01199 · Cited by 11
Dynamics of endothelial cells migration in nature-mimicking blood vessels
Du, Y., Xu, X., Yu, S., Wang, Y.-R., Liu, Y., Liu, F., Liu, W., Li, X.-L., Luo, H., Jing, G., et al. (2024) · Talanta · doi:10.1016/j.talanta.2024.126415 · Cited by 11
Making sense of scattering: Seeing microstructure through shear waves
Annio, G., Holm, S., Mangin, G., Penney, J., Bacquet, R., Mustapha, R., Darwish, O. I., Wittgenstein, A., Schregel, K., Vilgrain, V., et al. (2024) · Science Advances · doi:10.1126/sciadv.adp3363 · Cited by 11
Application progress of bio-manufacturing technology in kidney organoids
Mao, R., Zhang, J., Qin, H., Liu, Y., Xing, Y., & Zeng, W. (2025) · Biofabrication · doi:10.1088/1758-5090/adb4a1 · Cited by 12
Perfusable cell-laden matrices to guide patterning of vascularization in vivo
Parkhideh, S., Calderon, G. A., Janson, K. D., Mukherjee, S., Mai, A. K., Doerfert, M., Yao, Z., Sazer, D. W., & Omid Veiseh, A. (2022) · Biomaterials Science · doi:10.1039/d2bm01200f · Cited by 11
Moon, B., Li, K., Malic, L., Morton, K. J., Shao, H., Banh, L., Viswanathan, S., Young, E. W. K., & Veres, T. (2024) · Lab on a Chip · doi:10.1039/d4lc00530a · Cited by 11
Guan, H., Zhao, S., Fang, X., Miao, R., Zhang, Y., Zhang, Y., & Tian, J. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118445 · Cited by 11
Glänzer, L., Masalkhi, H. E., Roeth, A. A., Schmitz‐Rode, T., & Slabu, I. (2023) · Cancers · doi:10.3390/cancers15153773 · Cited by 10
Development and application of 3D cardiac tissues derived from human pluripotent stem cells
Ohno, M., Tani, H., & Tohyama, S. (2025) · Drug Metabolism and Pharmacokinetics · doi:10.1016/j.dmpk.2024.101049 · Cited by 9
Research progress on composite nerve guidance conduits with immune-regulatory functions
Zhang, S., Sun, X., Yang, X., Fan, Y., Liang, Y., Li, J., & Ling, J. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1622508 · Cited by 9
Baruch, E., Cohen, R., Silberman, E., Namestnikov, M., Cabilly, I., Shapira, A., & Dvir, T. (2025) · Advanced Materials · doi:10.1002/adma.202512879 · Cited by 9
3D bioprinting of tissues and organs for systemic diseases and localized injuries
Ng, W. K., & Bártolo, P. (2026) · Military Medical Research · doi:10.1016/j.mmr.2026.100006 · Cited by 18
Hierarchy of topological transitions in a network liquid
Neophytou, A., Starr, F. W., Chakrabarti, D., & Sciortino, F. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2406890121 · Cited by 8
3D bioprinting of tumor models and potential applications
Li, H., Qiao, Y., Dai, X., Tian, H., Han, Z., Cheng, S., Gao, P., & Cheng, H. (2024) · Bio-Design and Manufacturing · doi:10.1007/s42242-024-00317-y · Cited by 10
Biomaterials meet organ-on-chips – a perspective on tumor modeling
Monteiro, C. F., Deus, I. A., Custódio, C. A., & Mano, J. F. (2024) · International Materials Reviews · doi:10.1177/09506608241303436 · Cited by 9
Zirjawi, A. S., Xue, P., & Chaudhry, S. H. (2025) · Journal of Materials Research and Technology · doi:10.1016/j.jmrt.2025.01.093 · Cited by 8
Pan, X., Liu, S., Long, M., Peng, R., Hu, L., Liu, Y., & Huang, W. (2025) · Biomaterials Science · doi:10.1039/d5bm00734h · Cited by 8
Rahmani, S., Jafree, D. J., Lee, P. D., Tafforeau, P., Brunet, J., Nandanwar, S., Zhou, Y., Jacob, J., Bellier, A., Ackermann, M., et al. (2025) · npj Imaging · doi:10.1038/s44303-025-00090-2 · Cited by 15
Harnessing the power of bioprinting for the development of next-generation models of thrombosis
Liu, Y., Huang, T., Yap, N. A., Lim, K. S., & Ju, L. A. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.08.040 · Cited by 10
Current Status of Bioprinting Using Polymer Hydrogels for the Production of Vascular Grafts
Matějková, J., Kaňoková, D., & Matějka, R. (2024) · Gels · doi:10.3390/gels11010004 · Cited by 7
Son, J., Kim, D., Choi, J., Eom, S., Skylar‐Scott, M. A., Kim, D. S., & Kang, H. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202503334 · Cited by 7
Next-Gen Stroke Models: The Promise of Assembloids and Organ-on-a-Chip Systems
Lombardozzi, G., Szebényi, K., Giorgi, C., Topi, S., d’Angelo, M., Castelli, V., & Cimini, A. (2025) · Cells · doi:10.3390/cells14241986 · Cited by 7
Ntekoumes, D., & Gerecht, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137416 · Cited by 7
Mapping the blood vasculature in an intact human kidney using hierarchical phase-contrast tomographyPreprint
Rahmani, S., Jafree, D. J., Lee, P. D., Tafforeau, P., Brunet, J., Nandanwar, S., Jacob, J., Bellier, A., Ackermann, M., Jonigk, D. D., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.28.534566 · Cited by 7
Biomechanical and mechanobiological design for bioprinting functional microvasculature
Zhang, D., Liu, J., Liu, X., & Fan, Y. (2025) · Applied Physics Reviews · doi:10.1063/5.0227692 · Cited by 7
Zhao, Y., Khosravi, R., Cheung, K., Shen, K., Wang, Y., Landau, S., Okhovatian, S., Wu, Q., Lu, R. X. Z., Wagner, K. T., et al. (2025) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100075 · Cited by 7
Dai, Y., Zhao, F., Chen, Q., Zeng, B., Gu, W., Zhang, Y., Sun, F., Wang, X., Lin, X., Liu, N., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.08.035 · Cited by 8
Yeo, M., El-Mallah, J. C., Horchler, S., Waldron, O., Asgardoon, M. H., Jikaria, N. R., Dawes, J., Landmesser, M. E., Sun, M., Ozbolat, I. T., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123711 · Cited by 6
Rojek, K. O., Wrzos, A., Żukowski, S., Bogdan, M. J., Lisicki, M., Szymczak, P., & Guzowski, J. (2024) · APL Bioengineering · doi:10.1063/5.0180703 · Cited by 6
Bridging high resolution sub-cellular imaging with physiologically relevant engineered tissues
Kooh, Y. K. G., & Huebsch, N. (2024) · Frontiers in Mechanical Engineering · doi:10.3389/fmech.2024.1481933 · Cited by 7
Geometrically engineered organoid units and their assembly for pre-construction of organ structures
Kadotani, A., Hayase, G., & Yoshino, D. (2024) · APL Bioengineering · doi:10.1063/5.0222866 · Cited by 7
Acoustic holographic assembly of cell-dense tissue constructs
Shi, M., Fischer, P., & Melde, K. (2025) · Biofabrication · doi:10.1088/1758-5090/add49e · Cited by 6
Liu, S., Feng, K., Teng, Z., Zhao, R., Kang, X., Chen, Q., Yuan, Y., Li, X., & Wang, J. (2025) · Materials Horizons · doi:10.1039/d5mh00736d · Cited by 5
Bioprinted platform for parallelized screening of engineered microtissues in vivo
O’Connor, C. E., Zhang, F., Neufeld, A., Prado, O., Simmonds, S. P., Fortin, C. L., Johansson, F., Mene, J., Saxton, S. H., Kopyeva, I., et al. (2025) · Cell stem cell · doi:10.1016/j.stem.2025.03.002 · Cited by 5
Self-citationGao, Y., Xiao, J., Chen, Z., Ma, Y., Liu, X., Yang, D., Leo, H. L., Yu, H., Kong, J., & Guo, Q. (2023) · Biomaterials Science · doi:10.1039/d2bm01632j · Cited by 5
Microphysiological systems inspired by leaf venation
Mao, M., Meng, Z., He, J., & Li, D. (2024) · Trends in biotechnology · doi:10.1016/j.tibtech.2024.03.011 · Cited by 5
Palladino, A., Salerno, A., Crasto, A., Lucini, C., Maruccio, L., D’Angelo, L., Netti, P. A., de Girolamo, P., Cacchioli, A., Attanasio, C., et al. (2022) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2022.152019 · Cited by 5
Regenerative Engineering: Evolution and Its Modern Significance
Shi, Y., Zhang, L., Chen, M., Calle, E. A., & Langer, R. (2025) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-025-00498-7 · Cited by 4
Biomimetic structures for water management in proton exchange membrane fuel cells: A review
Wang, Z., Yang, J., Wang, H., Xiao, N., Li, A., Wang, R., & Ming, W. (2026) · International Journal of Electrochemical Science · doi:10.1016/j.ijoes.2026.101319 · Cited by 4
Advancing multiscale vascular engineering for regeneration and transplantation
Ju, Y., Hsiung, N., Zou, P., Zhao, H., Yang, K., Xiang, X., Feng, Y., Qiao, Z., Wang, B., Sun, Y., et al. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.175126 · Cited by 4
Kim, J. I., Kieu, T. T. T., & Lee, J. (2025) · Biomaterials Research · doi:10.34133/bmr.0185 · Cited by 4
Sono-uncaging for Spatiotemporal Control of Chemical Reactivity
Schrunk, E., Lee, S., Dutka, P., Wu, D. M., & Shapiro, M. G. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c09181 · Cited by 4
Chochola, V., Spustová, K., Lavický, J., Golunova, A. S., Pospíšil, J., Dvořáková, J., Kotelnikov, I., Kandra, M., Streit, L., Szklanny, A. A., et al. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01132 · Cited by 4
Gao, C., Cai, X., Li, J., Jiang, J., Bo, Q. I. A. N., Yang, R., & Xiong, F. (2026) · Burns · doi:10.1016/j.burns.2026.107874 · Cited by 4
Liu, Y., Zhang, Z., Li, H., Prados‐Martin, L., Li, H., Cheng, F., Tu, X., Lim, K. S., Li, W., & Wang, M. (2026) · Advanced Science · doi:10.1002/advs.74917 · Cited by 5
Xu, W., Atik, A. Y., Beker, L., & Koydemir, H. C. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116130 · Cited by 4
Song, J., Zhang, L., Song, B.-Q., & Yang, G. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.141020 · Cited by 2
Wang, J., Yang, X., Xu, M., Liu, H., Liu, L., & Tan, Z. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101033 · Cited by 4
Jeon, O., Park, H., Lee, M. S., & Alsberg, E. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.17.643708 · Cited by 4
Hybrid biofabricated blood vessel for medical devices testing
Portone, A., Ganzerli, F., Petrachi, T., Resca, E., Bergamini, V., Accorsi, L., Ferrari, A., Sbardelatti, S., Rovati, L. L., Mari, G., et al. (2024) · Science and Technology of Advanced Materials · doi:10.1080/14686996.2024.2404382 · Cited by 3
Wang, Z., Miao, X., Wu, X., Wu, Y., Han, T., Su, Y., Liu, P., Zhu, Z., & Xu, R. X. (2024) · Biomaterials Science · doi:10.1039/d4bm00880d · Cited by 3
State of Research on Tissue Engineering with 3D Printing for Breast Reconstruction
Velasquez, G. D. D. S., Tanas, Y., Taraballi, F., Herzog, T., & Spiegel, A. J. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14196737 · Cited by 4
Ahmed, I., Bryan, A. E., Bhuiyan, S. M., Harris, G. M., & Priye, A. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c00814 · Cited by 3
Conjugation of Proangiogenic Peptide to Enhance a Soft Tissue Bioink
Christensen, A. P., & Fisher, J. P. (2025) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.38011 · Cited by 3
Xu, L., Zhao, Y., Zhou, B., Liu, H., Sun, S., Ge, H., Wang, M., Zhou, M., Osuka, A., & Song, J. (2025) · Advanced Materials · doi:10.1002/adma.202516403 · Cited by 3
Demiral, M., Mamedov, A., & Köklü, U. (2026) · Eng—Advances in Engineering · doi:10.3390/eng7050235 · Cited by 3
Lin, Y., Tung, Y., Wong, J.-Y., & Wang, G. (2023) · Materials & Design · doi:10.1016/j.matdes.2023.111707 · Cited by 3
Midekssa, F. S., Davidson, C. D., Wieger, M. E., Kamen, J. L., Hanna, K. M., Jayco, D. K. P., Hu, M. M., Friend, N. E., Putnam, A. J., Helms, A. S., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.02.029 · Cited by 4
Engineered inflammation-induced neurodevelopmental disorders using a neurovascular-unit-on-a-chip
Zou, R., Shi, Z., Li, C., Xu, F., Zheng, X., Du, X., Huang, D., Qiu, B., & Ding, W. (2025) · Bio-Design and Manufacturing · doi:10.1631/bdm.2400107 · Cited by 3
Valchanov, P., Dukov, N. T., Pavlov, S., Kontny, A., & Dikova, T. D. (2023) · Gels · doi:10.3390/gels9070547 · Cited by 3
Marzio, N. D., Tognato, R., Bella, E. D., Giorgis, V. D., Manfredi, M., Cochis, A., Alini, M., & Serra, T. (2024) · Biomaterials and Biosystems · doi:10.1016/j.bbiosy.2024.100094 · Cited by 3
3D Printing of Aqueous Two‐Phase Systems with Linear and Bottlebrush Polyelectrolytes
Jin, Z., Seong, H., Srivastava, S., McGlasson, A., Emrick, T. S., Muthukumar, M., & Russell, T. P. (2024) · Angewandte Chemie · doi:10.1002/ange.202404382 · Cited by 3
A tube-based constitutive model of brain tissue with inner pressure
Liu, W., Yu, Z., Elkhodary, K. I., Xiao, H., Tang, S., Guo, T. F., & Guo, X. (2024) · Journal of the Mechanics and Physics of Solids · doi:10.1016/j.jmps.2024.105993 · Cited by 3
Choi, M., Choi, W., Hwang, P. T. J., Oh, Y., Jun, T., Ryu, D. Y., Kim, N. K., Jang, E. H., Shin, Y. R., Youn, Y.-N., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.142760 · Cited by 3
Monjure, T., Rosero, J., Ruley, J. A., Hernandez, A. J., Kima, P. E., & Porras, A. M. (2024) · GEN Biotechnology · doi:10.1089/genbio.2024.0020 · Cited by 2
Microvascular Regeneration and Perfusion of Partially Decellularized Tracheal Grafts
Sher, A. C., Liu, L., Izem, M., Calyeca, J., Meeker, M. O., & Chiang, T. (2024) · The Laryngoscope · doi:10.1002/lary.31801 · Cited by 2
Reactive Polymers of Intrinsic Microporous Aerogels for Rapid Mustard Gas Detoxification
Si, L., Zhu, J., Tang, P., Newton, M. A. A., Si, Y., Yu, J., Wang, X., & Dai, Z. (2025) · Small · doi:10.1002/smll.202503608 · Cited by 2
Dasgupta, S., Adhikari, J., Das, P., Sarkar, S., Datta, P., Chowdhury, A. R., & Barui, A. (2025) · ACS Applied Bio Materials · doi:10.1021/acsabm.5c00278 · Cited by 2
Palabıyık, A. A., & Palabıyık, E. (2025) · Nutrire · doi:10.1186/s41110-025-00381-z · Cited by 4
Pruett, L. J., Bahlmann, L. C., Ogi, R., Jiao, A., Roy, P., Johnson, M., Trumper, D. L., & Griffith, L. G. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202504936 · Cited by 2
4D force patterning enables spatial control of angiogenesis
Kheiri, S., Shah, J., Chai, P., Venkatesh, S. A., Flynn, R. A., Kamm, R. D., & Raman, R. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2532667123 · Cited by 2
Topological tracks patterned via 3D printing vascularize murine organ-scale constructs
Prado, O., Malkani, S., Johansson, F., Zhang, F., Fasuyi, A., Saxton, S. H., Kinstlinger, I. S., Miller, J. S., & Stevens, K. R. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2026.100369 · Cited by 2
Self-citationToward 4D printed functional soft tissues
Shabazz, A., Fitlin, J., Orozco-Contreras, H., Guo, S., Zhang, L. G., & Fisher, J. P. (2026) · Acta Biomaterialia · doi:10.1016/j.actbio.2026.02.035 · Cited by 4
Huang, Y.-H., Ono, A., & Sudo, R. (2026) · Regenerative Therapy · doi:10.1016/j.reth.2026.101086 · Cited by 2
Wright, C., Surendran, A., Lee, I., Villacres, J. E., Ezerins, A., Curtiss, A., Brown, N., Liu, J., Rothrock, B., Rios, P., et al. (2026) · Device · doi:10.1016/j.device.2026.101106 · Cited by 2
Biofabrication of Vascularized Tissues
Schimelman, J. B., Sun, Y., Lyu, C., Lu, T.-Y., Yao, E. J., Huang, L., Altera, A. K., Xiang, Y., & Chen, S. (2026) · Chemical Reviews · doi:10.1021/acs.chemrev.5c00914 · Cited by 2
Experimental model systems to study vascular aging
Tuna, B. G., Rey, A. B. A., Julve, J., Borrell-Pagés, M., Praet, M. V., Riches‐Suman, K., Roks, A. J. M., Rochfort, K. D., Keles, N. A., Tura-Ceide, O., et al. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103256 · Cited by 2
Jacketed elastomeric tubes for passive self-regulation of pulsatile flow
Jen, N., Hadfield, J., Bessa, G. M., Amabili, M., Nobes, D. S., & Chung, H. (2023) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2023.105994 · Cited by 2
An in vitro human vessel model to study Neisseria meningitidis colonization and vascular damages
Pinon, L., Chabaud, M., Nivoit, P., Wong-Ng, J., Nguyen, T. T., Paul, V., Bouquerel, C., Goussard, S., Smilovici, P., Frachon, E., et al. (2025) · eLife · doi:10.7554/elife.107813.3 · Cited by 1
A soft receiving platform for coaxial bioprinting cell-laden microtubes with uniform wall thickness
Wang, Z., Huang, C., Shi, Z., Liu, H., Han, X., Chen, Z., Li, S., Wang, Z., & Huang, J. S. (2025) · Applied Materials Today · doi:10.1016/j.apmt.2025.102599 · Cited by 2
Sun, A. Y., Lin, C. H., Tatka, J. A., Drake, K., Daily, S., Castellanos, M., Nelson, A., & Olanrewaju, A. O. (2025) · Progress in Additive Manufacturing · doi:10.1007/s40964-025-01081-w · Cited by 2
Netala, V. R., Hou, T., & Zhang, Z. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107171 · Cited by 2
An in vitro human vessel model to study Neisseria meningitidis colonization and vascular damagesPreprint
Pinon, L., Chabaud, M., Nivoit, P., Wong-Ng, J., Nguyen, T. T., Paul, V., Bouquerel, C., Goussard, S., Smilovici, P., Frachon, E., et al. (2025) · eLife · doi:10.7554/elife.107813.2 · Cited by 2
Photopatterned Sacrificial Vascular Architectures for Large Tissue-Scale OxygenationPreprint
Coates, I. A., Kohnke, C. A., Tan, Y. L., Alnasir, D. I., Nguyen, A., Heng, E., Kwan, A. T., Dulay, M. T., Schaar, B. T., Skylar‐Scott, M. A., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.27.708614 · Cited by 2
Aloni, R. (2023) · Progress in botany · doi:10.1007/124_2023_77 · Cited by 1
Injury-on-a-chip for modelling microvascular trauma-induced coagulation
Deal, H. E., Byrnes, E. M., Pandit, S., Sheridan, A. E., Brown, A. C., & Daniele, M. A.-A. (2024) · Lab on a Chip · doi:10.1039/d4lc00471j · Cited by 2
Ren, L., Nguyen, N., Yao, T., Nguyen, K. T., & Yuan, B. (2025) · Journal of Applied Physics · doi:10.1063/5.0235806 · Cited by 1
Saifi, A., Parimita, S., Kumar, A., & Ghosh, P. (2025) · ACS Applied Engineering Materials · doi:10.1021/acsaenm.5c00225 · Cited by 1
Engineering polystyrene microtube-embedded composite hydrogels for tunable vascular morphogenesis
Li, X., Khan, S., Wang, L., Chen, Y., Fang, X., Zhou, Y., & Wang, Y. I. (2025) · Biomedical Materials · doi:10.1088/1748-605x/adebd0 · Cited by 1
A multiscale vascular atlas of blood vessels supplying the urinary bladder of male and female mice
Bowden, L. D., Daglas, M., Osborne, P. B., & Keast, J. R. (2025) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00230.2025 · Cited by 1
Advanced strategies in organoids for metabolic monitoring and metabolic disease modeling
Ma, W., Xu, Y., Gu, Z., & Li, D. (2025) · Nano Research · doi:10.26599/nr.2025.94907988 · Cited by 1
Martorano, A. S., Reggio, C., Almeida, L. O., Scolaro, C., Raucci, L. M. S. D. C., Spriano, S., & de Oliveira, P. T. (2025) · Applied Surface Science Advances · doi:10.1016/j.apsadv.2025.100837 · Cited by 1
Zhang, Q., Xu, L., Zheng, Z., Zhang, Y., Song, P., Gao, J., Zhu, S., Shen, S., Sun, M., Yao, P. Q., et al. (2025) · Small Methods · doi:10.1002/smtd.202500585 · Cited by 1
WITHDRAWN: The Adverse Effects of Persistent Wound Stress on Patients with Type 2 Diabetes
Gao, C., Cai, X., Li, J., Jiang, J., Qian, B., Yang, R., & Xiong, F. (2025) · Burns · doi:10.1016/j.burns.2025.107765 · Cited by 1
RetractedSun, L., Wang, P. J., Lin, X., & Qiu, Y. (2025) · Chinese Journal of Plastic and Reconstructive Surgery · doi:10.1016/j.cjprs.2025.11.003 · Cited by 1
Lv, Q., Zhang, Y., & He, P. (2026) · Biomedical Materials · doi:10.1088/1748-605x/ae3996 · Cited by 2
Jalise, S. Z., Milan, P. B., Kialashaki, E., Ghane, M., Habibi, S., & Mehrabi, A. (2026) · Macromolecular Bioscience · doi:10.1002/mabi.202500453 · Cited by 1
A vascular-on-a-chip system recapitulates endothelial injury following ischemic reperfusion
Liu, Q., Ying, G., Hu, C., Li, H., Liu, R., Yang, C., Du, L., Zhang, H., Zhao, W., Qiao, P., et al. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.176831 · Cited by 1
Active filament dynamics model for the locomotion of C. elegans and soft microrobots
Hu, W., Amar, M. B., Yang, W., Wang, T., & Xu, F. (2026) · Journal of the Mechanics and Physics of Solids · doi:10.1016/j.jmps.2026.106656 · Cited by 1
Metadata
- Authors
- O’Connor, C., Brady, E., Zheng, Y., Moore, E., & Stevens, K. R.
- Affiliations
- University of Washington (US)
- University of Florida (US)
- Corresponding author
- Stevens, Kelly R.
- Venue
- Nature Reviews Materials
- Published
- 2022-05-31
- Volume
- 7
- Issue
- 9
- Pages
- 702-716
- ISSN
- 2058-8437 (ISSN-L)
- PMC
- PMC9154041
- OpenAlex
- W4281687739
- Cited by
- 271
- References
- 219
- Citations by year
- 2026: 66 · 2025: 80 · 2024: 74 · 2023: 41 · 2022: 10
- FWCI
- 4.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Reviews Materials (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation (R01HL141570)
- W. M. Keck Foundation
- American Heart Association
- National Institutes of Health (UG3TR002158)
- National Heart, Lung, and Blood Institute (R01HL141570)
- National Institute of General Medical Sciences (T32GM007266)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK128551)
- National Center for Advancing Translational Sciences
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Keywords
- vascular system, vascular engineering, bioprinting, organoids, microfluidics, engineered tissues, regenerative medicine, disease modeling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
