Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer

Derosa, Lisa, Routy, Bertrand, Thomas, Andrew Maltez, Iebba, Valerio, Zalcman, Gerard, Friard, Sylvie, Mazieres, Julien, Audigier-Valette, Clarisse +35 more·2022·Nature Medicine

Cited by (689)

Items 301–400 of 689

  1. Akkermansia muciniphila Metabolite Inosine Inhibits Castration Resistance in Prostate Cancer
    Yao Yu, Leqian Li, Qishen Yang, Jingwen Xue, Benlin Wang, Ming Xie, Wentai Shangguan, Zhangrui Zhu, Peng Wu · 2024 · Microorganisms
  2. Chemical genetic approaches to dissect microbiota mechanisms in health and disease
    Xinglin Yang, Howard C. Hang · 2024 · Science
  3. Gut metatranscriptomics based de novo assembly reveals microbial signatures predicting immunotherapy outcomes in non-small cell lung cancer
    Dávid Dóra, Peter Kiraly, Csenge Somodi, Balázs Ligeti, Edit Dulka, Gabriella Gálffy, Zoltán Lohinai · 2024 · Journal of Translational Medicine
  4. Gut microbiota affects pancreatic fibrotic progression through immune modulation in chronic pancreatitis
    Lu Liu, Tao Zhang, Yuhang Sui, Guanqun Li, Liwei Liu, Tianqi Lu, Hongtao Tan, Bei Sun, Xina Li, Le Li · 2023 · Microbial Pathogenesis
  5. Exploring the microbiome: Uncovering the link with lung cancer and implications for diagnosis and treatment
    Junqi Yi, Juanjuan Xiang, Jingqun Tang · 2023 · Chinese Medical Journal - Pulmonary and Critical Care Medicine
  6. Gut microbiota in cancer: insights on microbial metabolites and therapeutic strategies
    Yalan Chen, Xibin Wang, Yuwei Ye, Qian Ren · 2023 · Medical Oncology
  7. Metabolic Tumor Volume Assessed by 18F FDG–PET CT Scan as a Predictive Biomarker for Immune Checkpoint Blockers in Advanced NSCLC and Its Biological Correlates
    Filippo Gustavo Dall’Olio, Wael Zrafi, Véronique Roelants, Valentina Ambrosini, Aloÿse Fourquet, Cristina Mitea, Francesco Passiglia, Matteo Bauckneht, G. Bonardel, Nicole Conci et al. · 2024 · Clinical Cancer Research
  8. Narrative Review: Advancing Dysbiosis Treatment in Onco-Hematology with Microbiome-Based Therapeutic Approach
    Salomé Biennier, Mathieu Fontaine, Aurore Duquenoy, C. Schwintner, Joël Doré, Nathalie Corvaia · 2024 · Microorganisms
  9. Huaier enhances the antitumor effects of CDK 4/6 inhibitor by remodeling the immune microenvironment and gut microbiota in breast cancer
    Yifei Wang, Xiaolong Wang, Wenhao Li, Hanwen Huang, C. Di, Qifeng Yang · 2025 · Journal of Ethnopharmacology
  10. Aqueous extract of Sanghuangporus baumii induces autophagy to inhibit cervical carcinoma growth
    Di Wu, Xuemei Yuan, Ruijie Zhou, Wanchao Chen, Wen Li, Zhengpeng Li, Xueyin Li, Rui Zhu, Hualin Wang, Yan Yang · 2023 · Food & Function
  11. Epigenetic phase variation in the gut microbiome enhances bacterial adaptation
    Ni, Mi, Junker, Katerina, Liu, Yujie, Fan, Yu, Li, Yangmei, Qiao, Wanjin, Zhang, Xue-Song, Ksiezarek, Magdalena, Mead, Edward A., Tourancheau, Alan et al. · 2026 · Cell Host & Microbe
  12. The emerging role of microbiota in lung cancer: a new perspective on lung cancer development and treatment
    Chenxi Yan, Yanjie Chen, Yitao Tian, Shaojie Hu, Heng Wang, Xiaoxue Zhang, Qian Chu, Shanshan Huang, Wei Sun · 2025 · Cellular Oncology
  13. Gut microbiota predictive of the efficacy of consolidation immunotherapy and chemoradiotherapy toxicity in lung cancer
    Linfang Wu, Yitong Li, Wenqing Wang, Lei Deng, Hong Ge, Ming Cui, Nan Bi · 2025 · Med
  14. pH-responsive sparfloxacin/Fe3+ nanoparticles eradicate intratumoral bacteria and activate ferroptosis for enhanced antitumor immunotherapy in breast cancer
    Zhiting Sun, Ming Xu, Lu Nie, Changrong Wang, Jing Wu, Weiwei Wang, Shengbin Shi, Huijuan Song · 2025 · Biomaterials
  15. Soluble MAdCAM-1 as a biomarker in metastatic renal cell carcinoma
    Carolina Alves Costa Silva, Marc Machaalani, Renée Maria Saliby, Caiwei Zhong, Wanling Xie, Edoardo Pasolli, Gianmarco Piccinno, Cécile Dalban, Marine Fidelle, Aurélia Meurisse et al. · 2026 · Nature Medicine
  16. Mucin-degrading gut bacteria: context-dependent roles in intestinal homeostasis and disease
    Eunike Tiffany, Kyoung Su Kim, Panida Sittipo, Dong-Woo Lee, Yun Kyung Lee · 2026 · Gut Microbes
  17. Lung cancer, comorbidities, and medication: the infernal trio
    Hélène Pluchart, Sébastien Chanoine, Denis Moro‐Sibilot, CHRISTOS CHOUAID, Gil Frey, Julie Villa, Bruno Degano, Matteo Giaj Levra, Pierrick Bedouch, Anne‐Claire Toffart · 2024 · Frontiers in Pharmacology
  18. Qingfei mixture modulates the immune responses in lung cancer through modulating mTOR signaling and gut microbiota-derived short-chain fatty acids
    Qian Xiang, Zhuo Chen, Xuming Ji, Yongling Ji, Jin Wang, Yuan-Cai Liu, Xia-Cheng Zhou, Qinglin Li, Changyu Li, Aiqin Zhang · 2024 · Heliyon
  19. The Rational Engineered Bacteria Based Biohybrid Living System for Tumor Therapy
    Chen Wang, Qiliner Feng, Si Shi, Yuxuan Qin, Hongli Lu, Peng Zhang, Jie Liu, Baizhu Chen · 2024 · Advanced Healthcare Materials
  20. Gut microbiota and immunity in health and diseases: a review
    Michael Chukwuma Okolie, Great Iruoghene Edo, Irene Ebosereme Ainyanbhor, Agatha Ngukuran Jikah, Patrick Othuke Akpoghelie, Emad A. Yousif, Khalid Zainulabdeen, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Joshua Othuke Orogu et al. · 2024 · Proceedings of the Indian National Science Academy
  21. Gut microbiome and nutrition-related predictors of response to immunotherapy in cancer: making sense of the puzzle
    Cecilia Hes, Robert Thomas Jagoe · 2023 · BJC Reports
  22. Enhancing outcomes in medically inoperable early-stage NSCLC with gut-targeted antibiotics and stereotactic body radiotherapy: results from a randomized pilot study
    Steven Joel Feigenberg, Francesca Costabile, Ceylan Tanes, Kyle L. Bittinger, Roderick O'Connor, Divyansh Agarwal, Giorgos Skoufos, Silavano Salaris, Artemis G. Hatzigeorgiou, Νεκτάριος Κωστόπουλος et al. · 2025 · Journal for ImmunoTherapy of Cancer
  23. The microbial revolution: Akkermansia muciniphila's role in overcoming immunotherapy challenges
    Yujie Shi, Yu Fu, Dong Tang · 2025 · International Immunopharmacology
  24. Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner
    Daniel Peipert, Theresa L. Montgomery, Lucinda C. Toppen, Margaret Frances J. Lee, Matthew Scarborough, Dimitry N. Krementsov · 2025 · Frontiers in Immunology
  25. Microbial metabolite FAD mobilizes adipocyte lipid remodeling to enhance cancer immunotherapy efficacy
    Tianying Tong, Xiaowen Huang, Lingxi Li, Muni Hu, Xiaoqiang Zhu, Beiyao Zhu, Yanru Ma, Lijun Ning, Yi Jiang, Yue Zhang et al. · 2026 · Cell Metabolism
  26. Strain-level genetic heterogeneity and colonization dynamics drive microbiome therapeutic efficacy
    Kai Chen, Yina Liu, Jie Rong, Ningbin Dai, Caihua Xu, Heng Li, Ling Zhong, Baoyan Wang, Zhen Ji, Shichang Xie et al. · 2026 · Cell Host & Microbe
  27. Red Rice Seed Coat Targeting SPHK2 Ameliorated Alcoholic Liver Disease via Restored Intestinal Barrier and Improved Gut Microbiota in Mice
    Yuxu Chen, Zhiye Zhao, Shancheng Guo, Yaxian Li, Haiaolong Yin, Lei Tian, Guiguang Cheng, Ye Li · 2023 · Nutrients
  28. Advances in anti-tumor based on various anaerobic bacteria and their derivatives as drug vehicles
    Daichen Song, Xiaofan Yang, Yanfei Chen, Pingping Hu, Yingying Zhang, Yan Zhang, Ning Liang, Jian Xie, Lili Qiao, Guodong Deng et al. · 2023 · Frontiers in Bioengineering and Biotechnology
  29. Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals
    Yuxin Wang, Tatsuya Morishima, Maiko Sezaki, Ryo Sato, Gaku Nakato, Shinji Fukuda, Kouji Kobiyama, Ken J. Ishii, Yuhua Li, Hitoshi Takizawa · 2023 · EMBO Reports
  30. Circadian lifestyle determinants of immune checkpoint inhibitor efficacy
    Bethan R. Hughes, Sadiq Shanaz, Seline Ismail-Sutton, Nicholas I. Wreglesworth, Christian Peter Subbe, Pasquale F. Innominato · 2023 · Frontiers in Oncology
  31. The Role of Extracellular Vesicles in the Treatment of Prostate Cancer
    Cong Hu, Qi Chen, Tianyang Wu, Xinxing Du, Yanhao Dong, Zehong Peng, Wei Xue, Vijaya Sunkara, Yoon‐Kyoung Cho, Liang Dong · 2024 · Small
  32. Unravelling the prognostic and operative role of intratumoural microbiota in non‐small cell lung cancer: Insights from 16S rRNA and RNA sequencing
    Fuling Mao, Zixuan Hu, Ruifeng Shi, Hongbing Zhang, Zihe Zhang, Li Y, Xuanguang Li, Penghu Gao, Jinhui Li, Minghui Liu et al. · 2025 · Clinical and Translational Medicine
  33. Host-microbiota interactions in genitourinary cancer immunotherapy
    Xiaofeng Xu, Jin‐Long Cui, Wenhua Li, Yangyang Xu, Shuai Yuan, Xian‐Tao Zeng, Bing‐Hui Li · 2025 · Seminars in Cancer Biology
  34. Modulation of oral vaccine efficacy by the gut microbiota
    Yingying Hou, Jinqi Li, Yue Wu · 2025 · npj Vaccines
  35. Immune-based cancer therapies: mechanistic insights, clinical progress, and future directions
    Mahalakshmi Devaraji, Binoy Varghese Cheriyan · 2025 · Journal of the Egyptian National Cancer Institute
  36. Harnessing the Gut Microbiota to Improve Cancer Immunotherapy: Focus on Lung Cancer
    Uni Park, J. Heo, Seung-min Chun, June-Chul Lee, Se-Hoon Lee, Seungwon Lee · 2026 · Immune Network
  37. Long-term survival of patients with advanced non-small cell lung cancer treated using immune checkpoint inhibitors
    Akihiro Tamiya · 2023 · Respiratory Investigation
  38. Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7 th immunorad conference
    Pierre-Antoine Laurent, Fabrice André, Alexandre Bobard, Désirèe Deandreis, Sandra Demaria, Stéphane Depil, Stefan B. Eichmüller, Cristian Fernández-Palomo, Floris Foijer, Lorenzo Galluzzi et al. · 2024 · OncoImmunology
  39. A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy
    Chan Yeong Kim, Dong Jin Park, Beung‐Chul Ahn, Seungbyn Baek, Min Hee Hong, Linh Thanh Nguyen, Sun Ha Hwang, Nayeon Kim, Daniel Podlesny, Askarbek N Orakov et al. · 2024 · Nature Communications
  40. Gut and Intratumoral microbiota: Key to lung Cancer development and immunotherapy
    Junlan Cai, Weiguang Zhang, Shujing Zhu, Tianxin Lin, Renyan Mao, Ningzi Wu, Peipei Zhang, Mingqiang Kang · 2025 · International Immunopharmacology
  41. Immunotherapy response-associated Akkermansia: canary in a coal mine?
    Tina Cascone, Manoj Chelvanambi, Jennifer Ann Wargo · 2022 · Trends in Immunology
  42. Gut microbiome and cancer implications: Potential opportunities for fermented foods
    Sylvia L. Crowder, Heather Jim, Stephanie Hogue, Tiffany L. Carson, Doratha Armenthus Byrd · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  43. Demethylzeylasteral exerts potent efficacy against non-small-cell lung cancer via the P53 signaling pathway
    Linxi Lv, Feng Zhou, Yizhou Quan, Yiwei Fan, Yunjia Bao, Yaning Dou, Hongyan Qu, Xuanxuan Dai, Haiyang Zhao, Suqing Zheng et al. · 2024 · Translational Oncology
  44. Effects of chemotherapy and immunotherapy on microbial diversity in TME and engineered bacterial-mediated tumor therapy
    Heng Zheng, Xianxian Chen, Qiyang Li, Yuqi Liu, Jinzhong Cai · 2023 · Frontiers in Immunology
  45. Leveraging high-resolution omics data for predicting responses and adverse events to immune checkpoint inhibitors
    Angelo Limeta, Francesco Gatto, Markus J. Herrgård, Boyang Ji, Jens Nielsen · 2023 · Computational and Structural Biotechnology Journal
  46. Beyond probiotics: postbiotics sensitize cancer cells to immune checkpoint inhibitors
    Weici Laurence Liu, Zheshun Pi, Wenjun Mao · 2023 · Trends in cancer
  47. Targeting the gut and tumor microbiome in cancer treatment resistance
    Soňa Čierniková, Aneta Ševčíková, Michal Mego · 2024 · American Journal of Physiology-Cell Physiology
  48. Prior antibiotics, proton pump inhibitors, and probiotics in patients with extensive stage small cell lung cancer treated with immune checkpoint blockade: A post‐hoc analysis of the phase I/ III IMpower 133 trial
    Kazuki Takada, Shinkichi Takamori, Mototsugu Shimokawa, David James Pinato, Alessio Cortellini · 2024 · International Journal of Cancer
  49. Neoadjuvant immunotherapy for non-small cell lung cancer: Opportunities and challenges
    Junjie Hu, Jing Zhang, Shiyue Wan, Peng Zhang · 2024 · Chinese Medical Journal - Pulmonary and Critical Care Medicine
  50. Big lessons from the little Akkermansia muciniphila in hepatocellular carcinoma
    Yanguang Yang, Xinli Shi · 2025 · Frontiers in Immunology
  51. Carbon dioxide enhances Akkermansia muciniphila fitness and anti-obesity efficacy in high-fat diet mice
    Xiangfeng Wang, Qian‐Qian Yang, Changping Shi, Yuyang Wang, Dingming Guo, Xuchun Wan, Pengyuan Dong, Qianyao Zhang, Yueyan Hu, Ruilin Zhang et al. · 2025 · The ISME Journal
  52. The double-edged sword: impact of antibiotic use on immunotherapy efficacy in advanced hepatocellular carcinoma
    Yang Li, Ziwei Feng, Canhua Liang, Shaohuan Lu, GuangZhao Wang, Guangyi Meng · 2025 · BMC Gastroenterology
  53. Morphine and metformin impact immunotherapy benefit in patients with NSCLC: Results of the real-world study IFCT-1502 CLINIVO-SNDS
    Élisa Gobbini, Alexandra Langlais, Pascale Missy, Sébastien Chanoine, Benjamin Besse, Pierre-Jean Souquet, Fabrice Barlési, Clarisse Audigier-Valette, Anne-Cécile Métivier, I. Monnet et al. · 2025 · European Journal of Cancer
  54. Gut microbiota in cancer cachexia: a new frontier for research and therapy
    Colleen K. Ardis, Thi Phuong Nam Bui, Max Nieuwdorp · 2025 · Genes & Nutrition
  55. Engineered Akkermansia muciniphila vesicles for targeted pyroptosis and trained immunity to enhance immunotherapy in hepatocellular carcinoma
    Lanxiang Huang, Yuan Rong, Minghui Guo, Min Liu, Fei Long, Wei Zhong, Yue Hu, Xin He, Jiurong He, Diwei Zheng et al. · 2026 · Cell Reports Medicine
  56. Fecal microbiota transplantation for advanced non-small cell lung cancer with secondary PD-1 resistance efficacy prognostic factors and microbiome diversity analysis
    Hongxiang Huang, SuJuan Peng, Yangyang Liu, Li Chen, Fang Wu · 2026 · Journal of Translational Medicine
  57. Biodiversity and biogeography of the multi-kingdom cancer microbiome
    Anders B. Dohlman, Robin Mjelle, Henry M. Wood, Kevin Jiang, Alaina Shumate, Iris Lee, Gianmarco Piccinno, Garazi Serna, Abdul-Rakeem Yakubu, Paolo Giovanni Nuciforo et al. · 2026 · Cell
  58. Harnessing the Gut Microbiota to Potentiate the Efficacy of CAR T Cell Therapy
    Giulia Gabrielli, Roni Shouval, Guido Ghilardi, Marcel R.M. van den Brink, Marco Ruella · 2023 · HemaSphere
  59. Univariable and multivariable Mendelian randomization study identified the key role of gut microbiota in immunotherapeutic toxicity
    Baike Liu, Zheran Liu, Tianxiang Jiang, Xiangshuai Gu, Xiaonan Yin, Zhaolun Cai, Xiaoqiao Zou, Lei Dai, Bo Zhang · 2024 · European journal of medical research
  60. Severe infections in recipients of cancer immunotherapy: what intensivists need to know
    Adrien Joseph, Antoine Lafarge, Asma Mabrouki, Moustafa Abdel-Nabey, Yannick Binois, Romy Younan, Élie Azoulay · 2022 · Current Opinion in Critical Care
  61. Fecal microbiota in patients with a stoma decreases anaerobic bacteria and alters taxonomic and functional diversities
    Shunsuke A. Sakai, Masato Aoshima, Kentaro Sawada, Satoshi Horasawa, Ayumu Yoshikawa, Takao Fujisawa, Shigenori Kadowaki, Tadamichi Denda, Nobuhisa Matsuhashi, Hisateru Yasui et al. · 2022 · Frontiers in Cellular and Infection Microbiology
  62. Harnessing Microbiota to Improve Immunotherapy for Gastrointestinal Cancers
    Goc, Jeremy, Sonnenberg, Gregory F. · 2022 · Cancer Immunology Research
  63. Gut microbial signatures are associated with Lynch syndrome (LS) and cancer history in Druze communities in Israel
    Rawi Naddaf, Shaqed Carasso, Gili Reznick Levi, Erez Hasnis, Amalfi Qarawani, Itay Maza, Tal Gefen, Elizabeth Half, Naama Geva‐Zatorsky · 2023 · Scientific Reports
  64. Microbiome-derived bacterial lipids regulate gene expression of proinflammatory pathway inhibitors in systemic monocytes
    Saki Mihori, Frank C. Nichols, Anthony A. Provatas, Alyssa Matz, Beiyan Zhou, Christopher N. Blesso, Hunter A. Panier, Lauren Daddi, Yanjiao Zhou, Robert Brown Clark · 2024 · Frontiers in Immunology
  65. Probiotic administration aggravates dextran sulfate sodium salt-induced inflammation and intestinal epithelium disruption in weaned pig
    Kunhong Xie, Weidong Cai, Lingjie Li, Bing Yu, Yuheng Luo, Zhiqing Huang, Xiangbing Mao, Jie Yu, Ping Zheng, Hui Yan et al. · 2025 · Animal Microbiome
  66. The worldview of Akkermansia muciniphila, a bibliometric analysis
    Zhao Zhang, Jingyu Wang, Shaoqing Dang, Xingzi Liu, Yuemiao Zhang, Hong Zhang · 2025 · Frontiers in Microbiology
  67. Microbiota-Derived L-SeMet Potentiates CD8+ T Cell Effector Functions and Facilitates Anti-Tumor Responses
    Simiao Fan, Yaxin Li, Shaoyi Huang, Wen Wang, Biyu Zhang, Jiamei Zhang, Xiao-Xiao Jian, Zeng-Qing Song, Min Wu, Hai-Qing Tu et al. · 2025 · International Journal of Molecular Sciences
  68. Host and bacterial urine proteomics might predict treatment outcomes for immunotherapy in advanced non-small cell lung cancer patients
    Dávid Dóra, Péter Revisnyei, Alija Pašíć, Gabriella Gálffy, Edit Dulka, Anna Mihucz, Brigitta Roskó, Sára Szincsák, Anton B. Iliuk, Glen J. Weiss et al. · 2025 · Frontiers in Immunology
  69. Unraveling the Role of the Microbiota in Cancer Immunotherapy: A New Frontier
    Shouliang Wang, Shun Li, Mengli Zhang, Ruihan Liu, Xigang Ye, Siyi Mao, Jinming Yu, Xinhua Xie, Weige Tan · 2025 · Research
  70. Benzodiazepines interfere with the efficacy of pembrolizumab-based cancer immunotherapy. Results of a nationwide cohort study including over 50,000 participants with advanced lung cancer
    Montégut, Léa, Rousseau, Adrien, Ungolo, Cinzia, Derosa, Lisa, Fidelle, Marine, Alves Costa Silva, Carolina, Routy, Bertrand, Zitvogel, Laurence, Besse, Benjamin, Pasolli, Edoardo et al. · 2025 · OncoImmunology
  71. Exploring fecal microbiota signatures associated with immune response and antibiotic impact in NSCLC: insights from metagenomic and machine learning approaches
    Wenjie Han, Yuhang Zhou, Yiwen Wang, Xiaolin Liu, Tao Sun, Junnan Xu · 2025 · Frontiers in Cellular and Infection Microbiology
  72. Bacteriophages, Antibiotics and Probiotics: Exploring the Microbial Battlefield of Colorectal Cancer
    Volovat, Cristian Constantin, Cosovanu, Mihai Andrei, Ostafe, Madalina-Raluca, Augustin, Iolanda Georgiana, Volovat, Constantin, Georgescu, Bogdan, Volovat, Simona Ruxandra · 2025 · International Journal of Molecular Sciences
  73. Concomitant Comedications and Survival With First-Line Pembrolizumab in Advanced Non–Small-Cell Lung Cancer
    Adrien Rousseau, Noémie Simon‐Tillaux, Stefan Michiels, Lisa Derosa, Ariane Laparra, David Planchard, Jordi Remón, Fabrice Barlési, Pernelle Lavaud, Maxime Frélaut et al. · 2025 · JAMA Network Open
  74. Microbiota in drug resistance
    Ru Feng Jia, Chuanxing Xiao, Yonghai Zhang, Li-Yang Hu, Y. Jun-jun, Rui Zuo, Yufei Hu, Yu-hao Xie, Xuelei Ma, Qi Li et al. · 2025 · Drug Resistance Updates
  75. AI-enhanced synergistic chemo-immunotherapy: From mechanistic insights to clinical translation
    Sajid Muhammad, Bing Li, Wenda Zhong, H.L. Siddiqui, Yufen Zhao, Jinhui Wang · 2025 · Critical Reviews in Oncology/Hematology
  76. Microbiome and Heart Failure: A Comprehensive Review of Gut Health and Microbiota-Derived Metabolites in Heart Failure Progression
    Chukwudi Kingsley Orjichukwu, Rita Ogochukwu Orjichukwu, Peter Kanayochukwu Akpunonu, P.C. Okechukwu Ugwu, Somtochukwu Godfrey Nnabuife · 2025 · Medical Sciences
  77. Tumour-infiltrating microplastics disrupt the JAK-STAT-microbiota axis to promote immunotherapy resistance in colorectal cancer
    Zhaohui Jiang, Yongting Liu, Peng Zhang, Jiang Fei, Kailing Wang, Yin Li, Xiang-Yang Zhang, Changjing Cai, 逸鸿 陈, Yinghui Peng et al. · 2026 · Molecular Cancer
  78. Differential impact of proton pump inhibitors and antibiotics on immunotherapy efficacy after chemoradiotherapy in locally advanced non-small-cell lung cancer: a post-hoc analysis of the PACIFIC trial
    Leonardo Brunetti, Valentina Santo, David James Pinato, Fabrizio Citarella, Sarah Orlando, Fabian Acker, Vittoria Colella, Biagio Ricciuti, Jarushka Naidoo, Amin Nassar et al. · 2026 · The Lancet Oncology
  79. Akkermansia muciniphila and herbal medicine in immune-related diseases: current evidence and future perspectives
    Xue Ding, Pengfei Meng, Xiuxia Ma, Jing-Yu Yue, Liangping Li, Liran Xu · 2024 · Frontiers in Microbiomes
  80. Immunotherapy efficacy and toxicity: Reviewing the evidence behind patient implementable strategies
    Marthe Verhaert, Sandrine Aspeslagh · 2024 · European Journal of Cancer
  81. Bugs as drugs: Extended clinical applications and potential translational trends of Akkermansia muciniphila in oncology and comprehensive clinical investigation panorama of therapeutic microbiome modulators in gastric cancer treatment
    Yuning Wang, Peiwen Ma, Yibo Xian, Xianzhi Jiang, Shuhang Wang, Ning Li · 2024 · Pharmacological Research
  82. Targeting microbiome, drug metabolism, and drug delivery in oncology
    Ai Sumiyoshi, Hiroyuki Fujii, Yusuke Okuma · 2023 · Advanced Drug Delivery Reviews
  83. Antibiotic Therapy: The Cornerstone of Iatrogenic Resistance to Immune Checkpoint Inhibitors
    David James Pinato, Alessio Cortellini · 2023 · Journal of Clinical Oncology
  84. Cell Line-Dependent Internalization, Persistence, and Immunomodulatory Effects of Staphylococcus aureus in Triple-Negative Breast Cancer
    Sima Kianpour Rad, Runhao Li, Kenny K. L. Yeo, Clare M. Cooksley, Gohar Shaghayegh, Sarah Vreugde, Fangmeinuo Wu, Yoko Tomita, Timothy Jay Price, Wendy V. Ingman et al. · 2025 · Cancers
  85. The microbiome in head and neck squamous cell carcinoma: Biological drivers, therapeutic interactions, and emerging clinical applications
    A. Di Bello, A Scala, Riccardo Gili, Renato Falcicchia, Antonio Bassolino, Sara Polidori, F D’Auria, G. Tortora, Paolo Bossi, A. Cassano · 2026 · Critical Reviews in Oncology/Hematology
  86. A clinic-responder-derived defined microbial consortium enhances anti-PD-1 immunotherapy efficacy in mice
    Haiyan Zhou, Ruiming Sun, Xiaoqun Nie, Liliang Xia, Hui Dong, Yujie Liu, Shurui Hou, Wenyue Dong, Xiaokuan Zhu, Yaxian Yao et al. · 2026 · Nature Microbiology
  87. Potential role of gut microbes in the efficacy and toxicity of immune checkpoints inhibitors
    Jingxin Ma, Qi Wei, Xin Min Cheng, Jie Zhang, Zhongtao Zhang, Jianrong Su · 2023 · Frontiers in Pharmacology
  88. Revealing the therapeutic properties of gut microbiota: transforming cancer immunotherapy from basic to clinical approaches
    Rudradeep Hazra, Soumyadeep Chattopadhyay, Arijit Mallick, Sakuntala Gayen, Souvik Roy · 2024 · Medical Oncology
  89. Antithetical impacts of deleterious LRP1B mutations in non-squamous and squamous NSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trials
    Jinliang Wang, Wenyong Zhou, Yu Xu, Jianchun Duan, Qiaoxia Zhou, Guoqiang Wang, Leo Li, Chunwei Xu, Wenxian Wang, Shangli Cai et al. · 2024 · Science China Life Sciences
  90. Two microRNAs of plasma-derived small extracellular vesicles as biomarkers for metastatic non-small cell lung cancer
    Nan Geng, Yaopu Qi, Wen‐Wen Qin, Si Li, Hao Jin, Yifang Jiang, Xiuhuan Wang, Shan-na Wei, Ping Wang · 2023 · BMC Pulmonary Medicine
  91. The negative effect of concomitant medications on immunotherapy in non-small cell lung cancer: An umbrella review
    Jixin Chen, Shuqi Chen, Hui Luo, Shunqin Long, Xiaobing Yang, Wenfeng He, Wanyin Wu, Sumei Wang · 2023 · International Immunopharmacology
  92. A multi-cohort phase 1b trial of rituximab in combination with immunotherapy doublets in relapsed/refractory follicular lymphoma
    Reid W. Merryman, Robert Allyn Redd, Arnold S. Freedman, Inhye E. Ahn, Jennifer R. Brown, Jennifer Leigh Crombie, Matthew Steven Davids, David Christopher Fisher, Eric D. Jacobsen, Austin Injae Kim et al. · 2023 · Annals of Hematology
  93. Tackling the Immunotherapy Conundrum: Advances and Challenges for Operable Non-Small-Cell Lung Cancer Treatment
    Fouad Attieh, Antoine Chartouni, Marc Boutros, Antoine Mouawad, Hampig Raphaël Kourié · 2023 · Immunotherapy
  94. Clinical Applications of the Gut Microbiome in Genitourinary Cancers
    Charles B. Nguyen, Ulka N. Vaishampayan · 2024 · American Society of Clinical Oncology Educational Book
  95. Oncolytic Virotherapies and Adjuvant Gut Microbiome Therapeutics to Enhance Efficacy Against Malignant Gliomas
    Natalie M. Meléndez-Vázquez, Candelaria Gomez‐Manzano, Filipa Godoy‐Vitorino · 2024 · Viruses
  96. Characteristics of functional constipation and analysis of intestinal microbiota in children aged 0–4 in Zunyi region
    Shungang Gong, Zhengbo Yu, Yuan Ding, Yue Wang, Xi Li, Shengli Gu · 2025 · BMC Pediatrics
  97. Leveraging gut microbiota for enhanced immune checkpoint blockade in solid tumor therapy
    Jia Hu, Tang Feng, Ling Zhang, Qinghua Zhou, Ling‐Ling Zhu · 2025 · Chinese Medical Journal
  98. Gut microbial diversity is preserved through localised chemo-immunotherapy delivery in a KPC mouse model of pancreatic cancer
    Elahe Minaei, Paul Joyce, Samantha J. Wade, Christopher Brownlee, Chelsea Penney, Marie Ranson, Morteza Aghmesheh, Ronald Sluyter, Kara L. Vine · 2025 · Journal of Controlled Release
  99. The gut microbiome in lung cancer: from pathogenesis to precision therapy
    Miao Kevin Shi, Longfei Wang, Wentao Hu, Zhigang Liang · 2025 · Frontiers in Microbiology
  100. Integrating tumor macroenvironment, microenvironment and mechanobiology with organoid and organ-on-a-chip models for lung cancer immunotherapy
    Yeonhee Park, Da Hyun Kang, Chaeuk Chung · 2025 · Lung Cancer