The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Sustained human outbreak of a new MPXV clade I lineage in eastern Democratic Republic of the Congo
Open accessAbstract
Outbreaks of monkeypox (mpox) have historically resulted from zoonotic spillover of clade I monkeypox virus (MPXV) in Central Africa and clade II MPXV in West Africa. In 2022, subclade IIb caused a global epidemic linked to transmission through sexual contact. Here we describe the epidemiological and genomic features of an mpox outbreak in a mining region in eastern Democratic Republic of the Congo, caused by clade I MPXV. Surveillance data collected between September 2023 and January 2024 identified 241 suspected cases. Genomic analysis demonstrates a distinct clade I lineage divergent from previously circulating strains in the Democratic Republic of the Congo. Of the 108 polymerase chain reaction-confirmed mpox cases, the median age of individuals was 22 years, 51.9% were female and 29% were sex workers, suggesting a potential role for sexual transmission. The predominance of APOBEC3-type mutations and the estimated emergence time around mid-September 2023 imply recent sustained human-to-human transmission.
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IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era
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Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10
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Self-citationThe changing epidemiology of human monkeypox—A potential threat? A systematic review
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Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus
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Self-citationNew nomenclature for mpox (monkeypox) and monkeypox virus clades
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(2024) · doi:10.7554/elife.100545 · Cited by 16
Metadata
- Authors
- Vakaniaki, E. H., Kacita, C., Kinganda-Lusamaki, E., O’Toole, Á., Wawina-Bokalanga, T., Mukadi-Bamuleka, D., Amuri-Aziza, A., Malyamungu-Bubala, N., Mweshi-Kumbana, F., Mutimbwa-Mambo, L., Belesi-Siangoli, F., Mujula, Y., Parker, E., Muswamba-Kayembe, P.-C., Nundu, S. S., Lushima, R. S., Makangara-Cigolo, J.-C., Mulopo-Mukanya, N., Pukuta-Simbu, E., Akil-Bandali, P., Kavunga, H., Abdramane, O., Brosius, I., Bangwen, E., Vercauteren, K., Sam-Agudu, N. A., Mills, E. J., Tshiani-Mbaya, O., Hoff, N. A., Rimoin, A. W., Hensley, L. E., Kindrachuk, J., Baxter, C., de Oliveira, T., Ayouba, A., Peeters, M., Delaporte, E., Ahuka-Mundeke, S., Mohr, E. L., Sullivan, N. J., Muyembe-Tamfum, J.-J., Nachega, J. B., Rambaut, A., Liesenborghs, L., & Mbala-Kingebeni, P.
- Venue
- Nature Medicine
- Published
- 2024-06-13
- Volume
- 30
- Issue
- 10
- Pages
- 2791-2795
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W4399604997
- Cited by
- 404
- References
- 13
- FWCI
- 82.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Vakaniaki, E. H., Kacita, C., Kinganda-Lusamaki, E., O’Toole, Á., Wawina-Bokalanga, T., Mukadi-Bamuleka, D., Amuri-Aziza, A., Malyamungu-Bubala, N., Mweshi-Kumbana, F., Mutimbwa-Mambo, L., Belesi-Siangoli, F., Mujula, Y., Parker, E., Muswamba-Kayembe, P.-C., Nundu, S. S., Lushima, R. S., Makangara-Cigolo, J.-C., Mulopo-Mukanya, N., Pukuta-Simbu, E., . . . Mbala-Kingebeni, P. (2024). Sustained human outbreak of a new MPXV clade I lineage in eastern Democratic Republic of the Congo. Nature Medicine. https://doi.org/10.1038/s41591-024-03130-3
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
