Selective vulnerability in neurodegenerative diseases

WGCNA: an R package for weighted correlation network analysis

Langfelder, P., & Horvath, S. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-559 · Cited by 27,252

Neuropathological stageing of Alzheimer-related changes.

Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123

Staging of brain pathology related to sporadic Parkinson’s disease

Braak, H., Tredici, K. D., Rüb, U., de Vos, R. A. I., Jansen Steur, E. N. H., & Braak, E. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00065-9 · Cited by 10,777

Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases

Lin, M. T., & Beal, M. F. (2006) · Nature · doi:10.1038/nature05292 · Cited by 6,455

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Keren-Shaul, H., Spinrad, A., Weiner, A., Matcovitch-Natan, O., Dvir-Szternfeld, R., Ulland, T. K., David, E., Baruch, K., Lara-Astaiso, D., Toth, B., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.018 · Cited by 5,493

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

Whitehouse, P., Price, D., Struble, R., Clark, A., Coyle, J., & DeLong, M. R. (1982) · Science · doi:10.1126/science.7058341 · Cited by 3,627

SELECTIVE LOSS OF CENTRAL CHOLINERGIC NEURONS IN ALZHEIMER'S DISEASE

DAVIES, P. (1976) · The Lancet · doi:10.1016/s0140-6736(76)91936-x · Cited by 3,565

Alzheimer's disease: cell-specific pathology isolates the hippocampal formation.

Hyman, B. T., Van Hoesen, G. W., Damasio, A. R., & Barnes, C. L. (1984) · Science · doi:10.1126/science.6474172 · Cited by 2,268

Cryo-EM structures of tau filaments from Alzheimer’s disease

Fitzpatrick, A. W. P., Falcon, B., He, S., Murzin, A. G., Murshudov, G., Garringer, H. J., Crowther, R. A., Ghetti, B., Goedert, M., & Scheres, S. H. W. (2017) · Nature · doi:10.1038/nature23002 · Cited by 2,061

Ionic dependence of glutamate neurotoxicity

Choi, D. W. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-02-00369.1987 · Cited by 1,854

EEG/ERP evidence of possible hyperexcitability in older adults with elevated beta-amyloid

Devos, H., Gustafson, K. M., Liao, K., Ahmadnezhad, P., Estes, B. J., Martin, L. E., Mahnken, J. D., Brooks, W. M., & Burns, J. M. (2022) · Translational Neurodegeneration · doi:10.1186/s40035-022-00282-5 · Cited by 19

Hunting for the cause: Evidence for prion-like mechanisms in Huntington’s disease

Donnelly, K. M., Coleman, C. M., Fuller, M. L., Reed, V. L., Smerina, D., Tomlinson, D. S., & Pearce, M. M. P. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.946822 · Cited by 20

Cell competition from development to neurodegeneration

RODRIGUES, M. C., Couceiro, J., & Moreno, E. (2021) · Disease Models & Mechanisms · doi:10.1242/dmm.048926 · Cited by 22

Hypoxia and the Kynurenine Pathway: Implications and Therapeutic Prospects in Alzheimer’s Disease

Adeyemı, O. S., Awakan, O. J., Afolabi, B., Rotimi, D. E., Oluwayemi, E. T., Otuechere, C. A., Ibraheem, O., Elebiyo, T. C., Alejolowo, O. O., & Arowolo, A. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/5522981 · Cited by 20

An Update on the Application of Nano Phytomedicine as an Emerging Therapeutic Tool for Neurodegenerative Diseases

Hussain, M. S., Chaturvedi, V., Goyal, S., Singh, S., & Mir, R. H. (2023) · Current Bioactive Compounds · doi:10.2174/0115734072258656231013085318 · Cited by 20

Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans

Alexander-Floyd, J., Haroon, S., Ying, M., Entezari, A. A., Jaeger, C., Vermulst, M., & Gidalevitz, T. (2020) · BMC Biology · doi:10.1186/s12915-020-0750-5 · Cited by 19

Single-cell anatomical analysis of human hippocampus and entorhinal cortex uncovers early-stage molecular pathology in Alzheimer’s diseasePreprint

Dávila-Velderrain, J., Mathys, H., Mohammadi, S., Ruzicka, B., Jiang, X., Ng, A. P., Bennett, D. A., Tsai, L., & Kellis, M. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.01.450715 · Cited by 21

Identification of region-specific gene isoforms in the human brain using long-read transcriptome sequencing

Shimada, M., Omae, Y., Kakita, A., Gabdulkhaev, R., Hitomi, Y., Miyagawa, T., Honda, M., Fujimoto, A., & Tokunaga, K. (2024) · Science Advances · doi:10.1126/sciadv.adj5279 · Cited by 22

Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease

Homma, H., Tanaka, H., Fujita, K., & Okazawa, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073636 · Cited by 20

Modeling neurodevelopment in a dish with pluripotent stem cells

Imaizumi, K., & Okano, H. (2020) · Development Growth & Differentiation · doi:10.1111/dgd.12699 · Cited by 16

Regional heterogeneity in mitochondrial function underlies region specific vulnerability in human brain ageing: Implications for neurodegeneration

Anusha-Kiran, Y., Mol, P., Dey, G., Bhat, F. A., Chatterjee, O., Deolankar, S. C., Philip, M., Prasad, T. S. K., Bharath, M. M. S., & Mahadevan, A. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.09.027 · Cited by 19

Disease-associated oligodendrocyte signatures are spatiotemporally dysregulated in spinocerebellar ataxia type 3

Schuster, K. H., DiFranco, D. M., Putka, A. F., Mato, J. P., Jarrah, S. I., Stec, N. R., Sundararajan, V. O., & McLoughlin, H. S. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1118429 · Cited by 19

The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration

Fodder, K., de Silva, R., Warner, T. T., & Bettencourt, C. (2023) · Acta Neuropathologica Communications · doi:10.1186/s40478-023-01607-9 · Cited by 22

A Mechanism Underpinning the Bioenergetic Metabolism‐Regulating Function of Gold Nanocatalysts

Wang, Z., Henriques, A., Rouvière, L., Callizot, N., Tan, L., Hotchkin, M. T., Rossignol, R., Mortenson, M. G., Dorfman, A. R., Ho, K. S., et al. (2023) · Small · doi:10.1002/smll.202304082 · Cited by 18

Automated morphometric analysis with SMorph software reveals plasticity induced by antidepressant therapy in hippocampal astrocytes

Sethi, P., Virmani, G., Gupta, K., Thumu, S. C. R., Ramanan, N., & Marathe, S. V. (2021) · Journal of Cell Science · doi:10.1242/jcs.258430 · Cited by 17

Shapeshifter TDP-43: Molecular mechanism of structural polymorphism, aggregation, phase separation and their modulators

Doke, A. A., & Jha, S. K. (2023) · Biophysical Chemistry · doi:10.1016/j.bpc.2023.106972 · Cited by 17

Epigenetics in Neurodegenerative Diseases

van Zundert, B., & Montecino, M. A. (2025) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-75980-2_3 · Cited by 18

Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

Lee, W., Lavery, L. A., Rousseaux, M. W. C., Rutledge, E. B., Jang, Y., Wan, Y., Wu, S., Kim, W., Al‐Ramahi, I., Rath, S., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2020106106 · Cited by 17

Personalised regional modelling predicts tau progression in the human brain

Chaggar, P., Vogel, J. W., Binette, A. P., Thompson, T., Strandberg, O. T., Mattsson, N., Karlsson, L., Stomrud, E., Jbabdi, S., Magon, S., et al. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003241 · Cited by 19

The Proteostasis Network in Proteinopathies

Pytel, D., & Longo, J. F. (2025) · American Journal Of Pathology · doi:10.1016/j.ajpath.2025.07.011 · Cited by 18

Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology

Pan, J., Wang, P.-J., Zhang, J., Knapskog, A., Watne, L. O., Wang, H.-L., Lagartos-Donate, M. J., Lautrup, S., Mao, L.-P., Wang, Q., et al. (2026) · Nature Aging · doi:10.1038/s43587-026-01108-z · Cited by 20

Influence of the anatomical features of different brain regions on the spatial localization of fiber photometry signals

Montinaro, C., Pisanello, M., Bianco, M., Spagnolo, B., Pisano, F., Balena, A., Nuccio, F. D., Lofrumento, D. D., Verri, T., Vittorio, M. D., et al. (2021) · Biomedical Optics Express · doi:10.1364/boe.439848 · Cited by 16

A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C. elegans

Jung, R., Lechler, M. C., Fernández‐Villegas, A., Chung, C. W., Jones, H. C., Choi, Y. H., Thompson, M. A., Rödelsperger, C., Röseler, W., Schierle, G. S. K., et al. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3002284 · Cited by 31

Human‐Derived Induced GABAergic Progenitor Cells Improve Cognitive Function in Mice and Inhibit Astrocyte Activation with Anti‐Inflammatory Exosomes

Chen, C., Lan, Z., Tang, X., Chen, W., Zhou, X. W., Su, H., Su, R., Chen, Z., Chen, H., Guo, Y., et al. (2024) · Annals of Neurology · doi:10.1002/ana.27001 · Cited by 16

Mitochondrial Respiration Changes in R6/2 Huntington’s Disease Model Mice during Aging in a Brain Region Specific Manner

Burtscher, J., Pardo, A. D., Maglione, V., Schwarzer, C., & Squitieri, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155412 · Cited by 16

Neuroprotective Potential of Hesperidin as Therapeutic Agent in the Treatment of Brain Disorders: Preclinical Evidence-based Review

Bansal, K., Singh, V., Singh, S., & Mishra, S. (2023) · Current Molecular Medicine · doi:10.2174/1566524023666230320144722 · Cited by 16

Redox biology in neurodegenerative disorders

Abramov, A. Y. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.06.229 · Cited by 16

Alzheimer's disease

Serrano‐Pozo, A., Escott‐Price, V., Grinberg, L. T., Pascoal, T. A., Suárez‐Calvet, M., Dubois, B., & Sperling, R. A. (2026) · The Lancet · doi:10.1016/s0140-6736(26)00198-4 · Cited by 20

Artificial intelligence in drug discovery — what it is, where we stand and the path forward

Bender, A., Thomas, M. C., Scannell, J. W., Shaywitz, D. A., Ghiandoni, G. M., Greener, J. G., Pruteanu, L.-L., Jacobson, R. D., Handa, K., Hirano, M., et al. (2026) · Nature Reviews Drug Discovery · doi:10.1038/s41573-026-01496-2 · Cited by 23

Decreased 5‐HT1A binding in mild Alzheimer's disease—A positron emission tomography study

Mattsson, P., Cselényi, Z., Andrée, B., Borg, J., Nag, S., Halldin, C., & Farde, L. (2022) · Synapse · doi:10.1002/syn.22235 · Cited by 15

A Concise Review of the Recent Structural Explorations of Chromones as MAO-B Inhibitors: Update from 2017 to 2023

Ipe, R. S., Kumar, S., Benny, F., Jayan, J., Manoharan, A., Sudevan, S. T., George, G., Gahtori, P., Kim, H., & Mathew, B. (2023) · Pharmaceuticals · doi:10.3390/ph16091310 · Cited by 15

Selective vulnerability of parvocellular oxytocin neurons in social dysfunction

Tsurutani, M., Goto, T., Hagihara, M., Irie, S., & Miyamichi, K. (2024) · Nature Communications · doi:10.1038/s41467-024-53092-w · Cited by 15

Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

Kaczmarczyk, L., Bansal, V., Rajput, A., Rahman, R., Krzyżak, W., Degen, J., Poll, S., Fuhrmann, M., Bonn, S., & Jackson, W. S. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000374 · Cited by 13

Differences in topological progression profile among neurodegenerative diseases from imaging data

Garbarino, S., Lorenzi, M., Oxtoby, N. P., Vinke, E. J., Marinescu, R. V., Eshaghi, A., Ikram, M. A., Niessen, W. J., Ciccarelli, O., Barkhof, F., et al. (2019) · eLife · doi:10.7554/elife.49298 · Cited by 16

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease

Coccia, E., & Ahfeldt, T. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02326-5 · Cited by 16

Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices

Gray, A. L. H., Sawaya, M. R., Acharyya, D., Lou, J., Edington, E. M., Best, M. D., Prosser, R. A., Eisenberg, D. S., & Do, T. D. (2021) · Protein Science · doi:10.1002/pro.4268 · Cited by 14

Friend or Foe? The Varied Faces of Homeostatic Synaptic Plasticity in Neurodegenerative Disease

Taylor, H. B. C., & Jeans, A. F. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.782768 · Cited by 18

Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer’s disease

Datta, D., Perone, I., Morozov, Y. M., Arellano, J. I., Duque, A., RAKIC, P. T., van Dyck, C. H., & Arnsten, A. F. T. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad382 · Cited by 16

Molecular and cellular characteristics of cerebrovascular cell types and their contribution to neurodegenerative diseases

García, F., & Heiman, M. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00799-z · Cited by 14

The integrated stress response in the brain: cell type-specific functions in health and neurological disorders

Ho-Tieng, D., Sharma, V. K., Sonenberg, N., Gkogkas, C. G., & Khoutorsky, A. (2025) · Trends in Neurosciences · doi:10.1016/j.tins.2025.08.002 · Cited by 14

Tau polarizes an aging transcriptional signature to excitatory neurons and glia

Wu, T., Deger, J., Ye, H., Guo, C., Dhindsa, J. S., Pekarek, B. T., Al‐Ouran, R., Liu, Z., Al‐Ramahi, I., Botas, J., et al. (2023) · eLife · doi:10.7554/elife.85251 · Cited by 14

Longitudinal in vivo metabolic labeling reveals tissue-specific mitochondrial proteome turnover rates and proteins selectively altered by parkin deficiency

Stauch, K. L., Totusek, S., Trease, A. J., Estrella, L. D., Emanuel, K. M., Fangmeier, A., & Fox, H. S. (2023) · Scientific Reports · doi:10.1038/s41598-023-38484-0 · Cited by 15

Effects and mechanisms of bisphenols exposure on neurodegenerative diseases risk: A systemic review

Xu, Y., Nie, J., Lu, C., Hu, C., Chen, Y., Ma, Y., Huang, Y., & Lu, L. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170670 · Cited by 14

Strong Selectional Forces Fine-Tune CpG Content in Genes Involved in Neurological Disorders as Revealed by Codon Usage Patterns

Khandia, R., Sharma, A., Alqahtani, T., Alqahtani, A., Asiri, Y. I., Alqahtani, S., Alharbi, A. M., & Kamal, M. A. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.887929 · Cited by 14

A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation

Kundra, R., Dobson, C. M., & Vendruscolo, M. (2020) · iScience · doi:10.1016/j.isci.2020.100934 · Cited by 16

Genetic Influences on Hippocampal Subfields

Vilor‐Tejedor, N., Evans, T. E., Adams, H. H. H., Gónzalez‐de‐Echávarri, J. M., Molinuevo, J. L., Guigó, R., Gispert, J. D., & Operto, G. (2021) · Neurology Genetics · doi:10.1212/nxg.0000000000000591 · Cited by 12

Global hippocampal and selective thalamic nuclei atrophy differentiate chronic TBI from Non-TBI

Sandry, J. D., & Dobryakova, E. (2021) · Cortex · doi:10.1016/j.cortex.2021.08.011 · Cited by 15

MAP2 caps tau fibrils and inhibits aggregation

Holden, M. R., Krzesinski, B. J., Weismiller, H. A., Shady, J. R., & Margittai, M. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104891 · Cited by 13

Vesicular dysfunction and pathways to neurodegeneration

Lewis, P. A. (2021) · Essays in Biochemistry · doi:10.1042/ebc20210034 · Cited by 13

Deficient brain GABA metabolism leads to widespread impairments of astrocyte and oligodendrocyte function

Andersen, J. V., Marian, O. C., Qvist, F. L., Westi, E. W., Aldana, B. I., Schousboe, A., Don, A. S., Skotte, N. H., & Wellendorph, P. (2024) · Glia · doi:10.1002/glia.24585 · Cited by 13

Targeting complement C3/C3aR pathway restores rejuvenation factor PF4 and mitigates neurocognitive impairments in age-related perioperative neurocognitive disorders

Wang, J.-L., Ye, C.-H., Teng, Z.-F., Zhou, K., Pan, L.-L., Ouyan, M.-D., Zheng, Z., Meng, L. M., Li, S.-L., Zhang, J., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03103-z · Cited by 13

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

Kara, E., Crimi, A., Wiedmer, A. E., Emmenegger, M., Manzoni, C., Bandrés‐Ciga, S., D’Sa, K., Reynolds, R. H., Botía, J. A., Losa, M., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109189 · Cited by 12

Deficiency of ER Ca2+ sensor STIM1 in AgRP neurons confers protection against dietary obesity

Chen, Z., Pan, S., Yin, K., Zhang, Y., Yuan, X., Wang, S., Yang, S., Shen, Q. X., Tang, Y., Li, J., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109868 · Cited by 15

Clinicopathological heterogeneity of Alzheimer's disease with pure Alzheimer's disease pathology: Cases associated with dementia with Lewy bodies, very early‐onset dementia, and primary progressive aphasia

Kawakatsu, S., Kobayashi, R., Hayashi, H., Morioka, D., Utsunomiya, A., Kabasawa, T., Ohe, R., & Otani, K. (2021) · Neuropathology · doi:10.1111/neup.12765 · Cited by 12

A comprehensive bioinformatic analysis revealed novel MicroRNA biomarkers of Parkinson's disease

Rahimpour, A., Heidarzadehpilehrood, R., Abdollahi, S., Ranjbari, H., Shams, Z., Ghasemi, S. A., Najmaei, S., & Pirhoushiaran, M. (2022) · Cell Biology International · doi:10.1002/cbin.11869 · Cited by 13

Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease

Chhetri, G., Ke, Y., Wang, P., Usman, M., Li, Y., Sapp, E., Wang, J., Ghosh, A., Islam, M. A., Wang, X., et al. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202112073 · Cited by 12

mRNA isoform balance in neuronal development and disease

LaForce, G. R., Philippidou, P., & Schaffer, A. E. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1762 · Cited by 15

A Multi-Scale Computational Model of Excitotoxic Loss of Dopaminergic Cells in Parkinson's Disease

Muddapu, V. R., & Chakravarthy, V. S. (2020) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2020.00034 · Cited by 12

A molecular census of midbrain dopaminergic neurons in Parkinson’s diseasePreprint

Kamath, T., Abdulraouf, A., Burris, S. J., Gazestani, V., Nadaf, N. M., Vanderburg, C. R., & Macosko, E. Z. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.16.448661 · Cited by 13

An astrocyte-microglia MFG-E8 axis promotes synapse engulfment in early amyloid pathology

Sokolova, D., Puletti, F., Ghansah, S. A., Georgiades, T., Zheng, Y., Wu, L., Schepper, S. D., Lange, J., Ferreira, L. S. S., Sierksma, A., et al. (2026) · Neuron · doi:10.1101/2024.08.31.606944 · Cited by 15

Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics

Xia, M., Liu, Q., Zhang, W., Ge, J., & Mei, Z. (2025) · MedComm · doi:10.1002/mco2.70328 · Cited by 15

HnRNP Pathologies in Frontotemporal Lobar Degeneration

Jiang, X., Gatt, A. P., & Lashley, T. (2023) · Cells · doi:10.3390/cells12121633 · Cited by 13

Nuclear translocation of the LINE-1 encoded ORF1 protein alters nuclear envelope integrity in human neurons

Znaidi, R., Massiani-Beaudoin, O., Mailly, P., Monnet, H., Bonnifet, T., The Brainbank Neuro-CEB Neuropathology Network, Joshi, R. L., & Fuchs, J. (2025) · Brain Research · doi:10.1016/j.brainres.2025.149579 · Cited by 14

Using Proteomics to Understand Alzheimer’s Disease Pathogenesis

Drummond, E., & Wısnıewskı, T. (2019) · Codon Publications eBooks · doi:10.15586/alzheimersdisease.2019.ch3 · Cited by 13

Long‐distance regressive signaling in neural development and disease

Pathak, A., Clark, S. A., Bronfman, F. C., Deppmann, C. D., & Carter, B. D. (2020) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.382 · Cited by 12

Differential levels of inflammatory and neuroendocrine markers in the hippocampus and anterior cingulate cortex of bipolar disorder subjects: A post-mortem study

Nascimento, C. F., Nunes, P. V., Suemoto, C. K., Rodriguez, R. D., Leite, R. E. P., Grinberg, L. T., Pasqualucci, C. A., Nitríni, R., Filho, W. J., Brentani, H., et al. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.08.034 · Cited by 13

Carving the senescent phenotype by the chemical reactivity of catecholamines: An integrative review

Golubev, A. G. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101570 · Cited by 12

Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases

Reed, A. L., Mitchell, W., Alexandrescu, A. T., & Alder, N. N. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1263420 · Cited by 13

Cell-type-focused compound screen in human organoids reveals CK1 inhibition protects cone photoreceptors from death

Spirig, S. E., Herrero-Navarro, Á., Utz, L., Arteaga-Moreta, V. J., Raics, Z., Posada-Céspedes, S., Chreng, S., Galuba, O., Galuba, I., Claerr, I., et al. (2026) · Neuron · doi:10.1016/j.neuron.2026.02.024 · Cited by 11

Pre-plaque Aß-Mediated Impairment of Synaptic Depotentiation in a Transgenic Rat Model of Alzheimer’s Disease Amyloidosis

Qi, Y., Klyubin, I. V., Hu, N., Ondrejčák, T., & Rowan, M. J. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00861 · Cited by 12

Introduction for Stem Cell–Based Therapy for Neurodegenerative Diseases

Han, F., & Lu, P. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-4370-8_1 · Cited by 13

SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy

Muñiz, J. A., Facal, C. L., Urrutia, L., Clerici-Delville, R., Damianich, A., Ferrario, J. E., Falasco, G., & Avale, M. E. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.951384 · Cited by 12

Cerebellar Heterogeneity and Selective vulnerability in Spinocerebellar Ataxia Type 1 (SCA1)

Hamel, K. A., Labrada-Moncada, F. E., Sheeler, C. A., Rosa, J. S., Gilliat, S., Zhang, Y., & Cvetanović, M. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106530 · Cited by 11

Neuroprotective gap-junction-mediated bystander transformations in the adult zebrafish spinal cord after injury

Pedroni, A., Dai, Y.-W. E., Lafouasse, L., Chang, W., Srivastava, I., Vecchio, L. D., & Ampatzis, K. (2024) · Nature Communications · doi:10.1038/s41467-024-48729-9 · Cited by 11

Targeting Iron Responsive Elements (IREs) of APP mRNA into Novel Therapeutics to Control the Translation of Amyloid-β Precursor Protein in Alzheimer’s Disease

Khan, M. A. (2024) · Pharmaceuticals · doi:10.3390/ph17121669 · Cited by 11

The etiology and prevention of early‐stage tau pathology in higher cortical circuits: Insights from aging rhesus macaques

Datta, D., & Arnsten, A. F. T. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.14477 · Cited by 11

Neuroprotective Properties of Quinone Reductase 2 Inhibitor M-11, a 2-Mercaptobenzimidazole Derivative

Воронин, М. В., Андреевич, К. И., Зайнуллина, Л. Ф., Логвинов, И. О., Verbovaya, E. R., Антипова, Т. А., Vakhitova, Y. V., & Середенин, С. Б. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222313061 · Cited by 11

Connectome-based biophysics models of Alzheimer’s disease diagnosis and prognosis

Torok, J., Anand, C., Verma, P., & Raj, A. (2022) · Translational research · doi:10.1016/j.trsl.2022.08.008 · Cited by 11

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Quach, T., Stratton, H. J., Khanna, R., Mackey-Alfonso, S. E., Deems, N., Honnorat, J., Meyer, K., & Duchemin, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232214188 · Cited by 12

Somatic copy number variant load in neurons of healthy controls and Alzheimer’s disease patients

Turan, Z. G., Richter, V., Bochmann, J., Parvizi, P., Yapar, E., Işıldak, U., Waterholter, S.-K., Leclère-Turbant, S., Son, Ç. D., Duyckaerts, C. J., et al. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01452-2 · Cited by 12

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Müller, C., Li, P., Wang, Y., Dong, M., Tian, B., & Chen, M. (2022) · Materials Today Nano · doi:10.1016/j.mtnano.2023.100311 · Cited by 11

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Bose, R., Spulber, S. D., & Ceccatelli, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054338 · Cited by 12

Long-Term Dynamic Changes of NMDA Receptors Following an Excitotoxic Challenge

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The brain—from neurodevelopment to neurodegeneration

Abramov, A. Y. (2022) · FEBS Journal · doi:10.1111/febs.16436 · Cited by 11

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Khalid, T., Malik, A., Rasool, N., Kanwal, A., Nawaz, H., & Almas, I. (2025) · RSC Advances · doi:10.1039/d4ra07438f · Cited by 12

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Lee, E. J., Park, D. Y., Han, J. C., & Kee, C. (2025) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2025.101379 · Cited by 13

Matcha and Its Components Control Angiogenic Potential

Ryota, I. W. A. I., Ishii, T., Fukushima, Y., Okamoto, T., Ichihashi, M., Sasaki, Y., & MIZUATNI, K.-I. (2021) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.67.118 · Cited by 15

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Menéndez‐González, M. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13041 · Cited by 12

The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling

Gayen, M., Benoit, M., Fan, Q., Hudobenko, J., & Yan, R. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102532 · Cited by 10

Patterns of structure-function association in normal aging and in Alzheimer's disease: Screening for mild cognitive impairment and dementia with ML regression and classification models

Statsenko, Y. A., Meribout, S., Habuza, T., Almansoori, T. M., Gorkom, K., Gelovani, J. G., & Ljubisavljević, M. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.943566 · Cited by 10

Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions

Ferreira, C., Pinto, M. F., Macedo‐Ribeiro, S., Pereira, P. J. B., Rocha, F. A., & Martins, P. M. (2020) · Physical Chemistry Chemical Physics · doi:10.1039/d0cp02469d · Cited by 10

Tissue-specific safety mechanism results in opposite protein aggregation patterns during agingPreprint

Jung, R., Lechler, M. C., Rödelsperger, C., Röseler, W., Sommer, R. J., & David, D. C. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.04.409771 · Cited by 10

Dysregulation of neuroproteasomes by ApoE isoforms drives endogenous Tau aggregationPreprint

Paradise, V., Sabu, M., Bafia, J., Sharif, N., Nguyen, C., Konrad-Vicario, K., Mukim, R. D., Wang, X., Corjuc, B., Fu, J. M., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.29.518293 · Cited by 10

Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomicsPreprint

Rexach, J. E., Cheng, Y., Chen, L., Polioudakis, D., Lin, L., Mitri, V., Elkins, A. G., Yin, A., Calini, D., Kawaguchi, R., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.29.560245 · Cited by 10

Patterning the cerebral cortex into distinct functional domains during development

Appan, D., Hsu, S.-M., Hsu, W.-H., & Chou, S. (2023) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2023.102698 · Cited by 15

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Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases

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Alzheimer's Disease Selective Vulnerability and Modelling in Transgenic Mice

Götz, J., Nicole, S., Vissel, B., & Ittner, L. M. (2011) · Advances in Alzheimer's disease · doi:10.3233/978-1-60750-733-8-49 · Cited by 1

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Götz, J., Schönrock, N., Vissel, B., & Ittner, L. M. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1143 · Cited by 38

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Catastrophic cliffs: a partial suggestion for selective vulnerability in neurodegenerative diseases

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