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TREM2 deficiency exacerbates cognitive impairment by aggravating α-Synuclein-induced lysosomal dysfunction in Parkinson’s disease

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Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils

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Natural Compounds That Activate the KEAP1/Nrf2 Signaling Pathway as Potential New Drugs in the Treatment of Idiopathic Parkinson’s Disease

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Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation

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Pathological Involvement of Protein Phase Separation and Aggregation in Neurodegenerative Diseases

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⍺-Synuclein Structural Diversity and the Cellular Environment in ⍺-Synuclein Transmission Models and Humans

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Is Multiple System Atrophy a Prion-like Disorder?

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LRRK2 Ablation Attenuates Alpha-Synuclein–Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo

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Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

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Mesoscale connections and gene expression empower whole-brain modeling of α-synuclein spread, aggregation, and decay dynamics

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Infections in the Etiology of Parkinson’s Disease and Synucleinopathies: A Renewed Perspective, Mechanistic Insights, and Therapeutic Implications

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α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

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Oligomeric alpha-synuclein causes early synaptic dysfunction of the corticostriatal pathway associated with non-motor symptoms

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Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils

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Hypoxic stress accelerates the propagation of pathological alpha‐synuclein and degeneration of dopaminergic neurons

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Quantum-dot-labeled synuclein seed assay identifies drugs modulating the experimental prion-like transmission

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Feed-forward metabotropic signaling by Cav1 Ca2+ channels supports pacemaking in pedunculopontine cholinergic neurons

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Behavioral Deficits and Brain α-Synuclein and Phosphorylated Serine-129 α-Synuclein in Male and Female Mice Overexpressing Human α-Synuclein

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Construct, Face, and Predictive Validity of Parkinson’s Disease Rodent Models

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Site-specific seeding of Lewy pathology induces distinct pre-motor cellular and dendritic vulnerabilities in the cortex

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Anisotropic diffusion and traveling waves of toxic proteins in neurodegenerative diseases

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Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity

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Pronounced α-Synuclein Pathology in a Seeding-Based Mouse Model Is Not Sufficient to Induce Mitochondrial Respiration Deficits in the Striatum and Amygdala

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α-Synuclein aggregation decreases cortico-amygdala connectivity and impairs social behavior in mice

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A review of brain injury at multiple time scales and its clinicopathological correlation through in silico modeling

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Targets to Search for New Pharmacological Treatment in Idiopathic Parkinson’s Disease According to the Single-Neuron Degeneration Model

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Magnetic Resonance Imaging Texture of Medial Pulvinar in Dementia with Lewy Bodies

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Neuroanatomical correlates of polygenic risk for Parkinson’s DiseasePreprint

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A network-level transport model of tau progression in the Alzheimer’s brain

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Neuronal ApoE Regulates the Cell-to-Cell Transmission of α-Synuclein

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Synapses do not facilitate prion-like transfer of alpha-synuclein: a quantitative study in reconstructed unidirectional neural networks

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Contrastive machine learning reveals Parkinson’s disease specific features associated with disease severity and progression

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IC100 blocks inflammasome activation induced by α-synuclein aggregates and ASC specks

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Differential pathological dynamics triggered by distinct Parkinson patient–derived α-synuclein extracts in nonhuman primates

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Network spreading and local biological vulnerability in amyotrophic lateral sclerosis

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Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain

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Translating Pathological Brain Activity Primers in Parkinson’s Disease Research

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Striato-cortical functional connectivity changes in mild cognitive impairment with Lewy bodies

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Proteomic Complexity in Parkinson’s Disease: A Redox Signaling Perspective of the Pathophysiology and Progression

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LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons

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Beyond Just Connectivity — Neuronal Activity Drives α‐Synuclein Pathology

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Olfactory Dysfunction as a Clinical Marker of Early Glymphatic Failure in Neurodegenerative Diseases

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Neuromodulation modifies α-synuclein spreading dynamics in vivo and the pattern is predicted by changes in whole-brain function

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Crucial Role of FABP3 in αSyn-Induced Reduction of Septal GABAergic Neurons and Cognitive Decline in Mice

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Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

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Connectivity and vulnerability determine α-synuclein spread

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[Re] Spread of alpha-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis

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The connectome is necessary but not sufficient for the spread of alpha -synuclein pathology in ratsPreprint

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Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

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